EP1061800A4 - COMPOSITIONS AND METHODS MODULATING VASCULARIZATION - Google Patents

COMPOSITIONS AND METHODS MODULATING VASCULARIZATION

Info

Publication number: EP1061800A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods modulating; vascularization; modulating vascularization; methods
Prior art date: 1998-03-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP99912344A

Other languages

German (de)

French (fr)

Other versions

EP1061800A1 (en

Inventor

Jeffrey M Isner

Takayuki Asahara

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

St Elizabeths Medical Center of Boston Inc

Original Assignee

Caritas St Elizabeth Medical Center of Boston

St Elizabeths Medical Center of Boston Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-09

Filing date

1999-03-09

Publication date

2004-10-06

1999-03-09 Application filed by Caritas St Elizabeth Medical Center of Boston, St Elizabeths Medical Center of Boston Inc filed Critical Caritas St Elizabeth Medical Center of Boston

2000-12-27 Publication of EP1061800A1 publication Critical patent/EP1061800A1/en

2004-10-06 Publication of EP1061800A4 publication Critical patent/EP1061800A4/en

Status Withdrawn legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Cell Biology (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Virology (AREA)
Cardiology (AREA)
Tropical Medicine & Parasitology (AREA)
Microbiology (AREA)
Developmental Biology & Embryology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP99912344A 1998-03-09 1999-03-09 COMPOSITIONS AND METHODS MODULATING VASCULARIZATION Withdrawn EP1061800A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US7726298P	1998-03-09	1998-03-09
US77262P		1998-03-09
PCT/US1999/005130 WO1999045775A1 (en)	1998-03-09	1999-03-09	Compositions and methods for modulating vascularization

Publications (2)

Publication Number	Publication Date
EP1061800A1 EP1061800A1 (en)	2000-12-27
EP1061800A4 true EP1061800A4 (en)	2004-10-06

Family

ID=22137044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP99912344A Withdrawn EP1061800A4 (en)	1998-03-09	1999-03-09	COMPOSITIONS AND METHODS MODULATING VASCULARIZATION

Country Status (5)

Country	Link
EP (1)	EP1061800A4 (en)
JP (2)	JP2002506008A (en)
AU (1)	AU766238B2 (en)
CA (1)	CA2322559C (en)
WO (1)	WO1999045775A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2810249A1 (en) *	2000-06-05	2001-12-13	The Trustees Of Columbia University In The City Of New York	Identification and use of human bone marrow-derived endothelial progenitor cell to improve myocardial function after ischemic injury
WO2001098344A2 (en) *	2000-06-16	2001-12-27	Curis, Inc.	Angiogenesis-modulating compositions and uses
AU2001284695A1 (en)	2000-07-31	2002-02-13	New York Medical College	Methods and compositions for the repair and/or regeneration of damaged myocardium
US7862810B2 (en)	2000-07-31	2011-01-04	New York Medical College	Methods and compositions for the repair and/or regeneration of damaged myocardium
US7547674B2 (en) *	2001-06-06	2009-06-16	New York Medical College	Methods and compositions for the repair and/or regeneration of damaged myocardium
CA2421966A1 (en) *	2000-09-13	2003-03-11	Chugai Seiyaku Kabushiki Kaisha	Remedies for ischemic diseases
JP2004512124A (en) *	2000-10-30	2004-04-22	チルドレンズ　メディカル　センター　コーポレーション	Tissue-engineered vascular structure
CA2467557A1 (en) *	2001-11-19	2003-05-30	Kyowa Hakko Kogyo Co., Ltd.	Agent which mobilizes multipotential stem cells from tissues to peripheral blood
JPWO2003059375A1 (en) *	2002-01-17	2005-05-19	株式会社カルディオ	Tissue regeneration combination therapy
KR100562824B1 (en)	2002-03-20	2006-03-23	주식회사 바이로메드	Hybrid hepatocyte growth factor gene that expresses two genes of hepatocyte growth factor with high gene expression efficiency
US20030199464A1 (en)	2002-04-23	2003-10-23	Silviu Itescu	Regeneration of endogenous myocardial tissue by induction of neovascularization
KR20050042162A (en) *	2002-08-16	2005-05-04	쉐링 악티엔게젤샤프트	Gene therapy for critical limb ischemia with wild type or mutant enos
US20040037811A1 (en) *	2002-08-22	2004-02-26	The Cleveland Clinic Foundation	Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy
AU2008200822A1 (en) *	2002-08-22	2008-03-13	The Cleveland Clinic Foundation	Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy
CN100366257C (en) *	2002-08-22	2008-02-06	克里夫兰诊所基金会	Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy
CA2509618A1 (en) *	2002-12-13	2004-07-01	Hisayoshi Fujiwara	Pharmaceutical compositions for treating non-ischemic heart failure
US7695723B2 (en) *	2002-12-31	2010-04-13	Sygnis Bioscience Gmbh & Co. Kg	Methods of treating neurological conditions with hematopoietic growth factors
TW200605910A (en) *	2004-04-30	2006-02-16	Orbus Medical Technologies Inc	Medical device with coating for capturing genetically-altered cells and methods for using same
EP1803464A4 (en) *	2004-09-17	2009-09-09	Cellgentech Inc	External preparation for treating skin ulcer
WO2006075587A1 (en) *	2005-01-11	2006-07-20	National University Corporation Nagoya University	Csf-containing remedy to be administered in low dose
JPWO2006093172A1 (en) *	2005-02-28	2008-08-07	財団法人先端医療振興財団	In vitro amplification of adult stem cells
AU2008232739B2 (en)	2007-03-30	2014-03-27	The Cleveland Clinic Foundation	Method of treating ischemic disorders
CA2743184A1 (en)	2007-11-09	2009-05-14	New York Medical College	Methods and compositions for the repair and/or regeneration of damaged myocardium using cytokines and variants thereof
US8512696B2 (en)	2007-11-30	2013-08-20	Autologous, Llc	Methods of isolating non-senescent cardiac stem cells and uses thereof
WO2009073594A1 (en)	2007-11-30	2009-06-11	New York Medical College	Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
AU2008334058B2 (en)	2007-11-30	2014-07-10	New York Medical College	Compositions comprising vascular and myocyte progenitor cells and methods of their use
AU2008338525B2 (en)	2007-12-14	2015-04-02	Juventas Therapeutics, Inc.	Compositions and methods of promoting wound healing
US20090258932A1 (en)	2008-04-09	2009-10-15	Viromed Co., Ltd.	Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA
EP2473196B1 (en)	2009-08-28	2017-05-31	The Cleveland Clinic Foundation	Sdf-1 delivery for treating ischemic tissue
WO2012148200A2 (en) *	2011-04-26	2012-11-01	아주대학교 산학협력단	Composition for aiding surgical procedures for treating ischemic vascular diseases
KR101609690B1 (en) *	2011-04-26	2016-04-06	아주대학교산학협력단	Surgical or Procedural Sub-composition for Treating Ischemic Vascular Disease
KR101336386B1 (en) *	2011-06-17	2013-12-04	전북대학교병원	Revellent lymph blood vessel
RU2639582C2 (en)	2013-10-22	2017-12-21	Виромед Ко., Лтд.	Composition for prevention or treatment of amyotrophic lateral sclerosis using two or more hepatocytes growth factor isophorms
US11744858B2 (en)	2015-03-18	2023-09-05	Foundation For Biomedical Research And Innovation At Kobe	Medicine for treatment and/or prevention of ischemic diseases, method for improving angiogenesis-promoting activity of cells, or method for producing medicine
CN112088017B (en)	2018-07-19	2023-11-21	赫利世弥斯株式会社	Freeze-dried pharmaceutical composition for naked deoxyribonucleic acid gene therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998019712A1 (en) *	1996-11-08	1998-05-14	St. Elizabeth's Medical Center Of Boston, Inc.	Methods for regulating angiogenesis

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US4808042A (en) *	1982-06-11	1989-02-28	Electro-Plasma, Inc.	Powder feeder
US4879282A (en) *	1987-03-17	1989-11-07	Saliba Jr Michael J	Medical application for heparin and related molecules
US4808402A (en) *	1987-05-29	1989-02-28	Northwestern University	Method and compositions for modulating neovascularization
US5880090A (en) *	1997-09-19	1999-03-09	The Hope Heart Institute	Treatment of vascular graft implants with G-CSF

1999
- 1999-03-09 JP JP2000535201A patent/JP2002506008A/en not_active Withdrawn
- 1999-03-09 EP EP99912344A patent/EP1061800A4/en not_active Withdrawn
- 1999-03-09 CA CA2322559A patent/CA2322559C/en not_active Expired - Fee Related
- 1999-03-09 AU AU30737/99A patent/AU766238B2/en not_active Ceased
- 1999-03-09 WO PCT/US1999/005130 patent/WO1999045775A1/en active IP Right Grant
2010
- 2010-07-12 JP JP2010157554A patent/JP2010265301A/en active Pending

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998019712A1 (en) *	1996-11-08	1998-05-14	St. Elizabeth's Medical Center Of Boston, Inc.	Methods for regulating angiogenesis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ASAHARA TAKAYUKI ET AL: "Vasculogenesis, developed by endothelial progenitor cells, has significant role in neovascularization in severe ischemia", CIRCULATION, vol. 96, no. 8 SUPPL., 21 October 1997 (1997-10-21), & 70TH SCIENTIFIC SESSIONS OF THE AMERICAN HEART ASSOCIATION; ORLANDO, FLORIDA, USA; NOVEMBER 9-12, 1997, pages I415 - I416, XP008033796, ISSN: 0009-7322 *
FLAMME INGO ET AL: "Induction of vasculogenesis and hematopoiesis in vitro", DEVELOPMENT (CAMBRIDGE), vol. 116, no. 2, 1992, pages 435 - 439, XP002291992, ISSN: 0950-1991 *
KALKA C ET AL: "Angiogenese und Vaskulogenese", HERZ, URBAN UND VOGEL, MUENCHEN, DE, vol. 25, no. 6, 2000, pages 611 - 622, XP002971995, ISSN: 0340-9937 *
See also references of WO9945775A1 *

Also Published As

Publication number	Publication date
WO1999045775A1 (en)	1999-09-16
JP2010265301A (en)	2010-11-25
CA2322559A1 (en)	1999-09-16
CA2322559C (en)	2012-07-17
AU3073799A (en)	1999-09-27
EP1061800A1 (en)	2000-12-27
JP2002506008A (en)	2002-02-26
AU766238B2 (en)	2003-10-09

Publication	Publication Date	Title
EP1061800A4 (en)	2004-10-06	COMPOSITIONS AND METHODS MODULATING VASCULARIZATION
DE69918233D1 (en)	2004-07-29	POLYMOLIC ACID COMPOSITION AND FILM MADE THEREOF
FR2781666B1 (en)	2000-09-08	SOLID COSMETIC COMPOSITION AND USES THEREOF
NO20005913D0 (en)	2000-11-22	Medicinal Composition
FI974141A7 (en)	1999-05-06	Utilizing the content of the message
ID26926A (en)	2001-02-22	SHAMPO COMPOSITION FORM MODE
ID26186A (en)	2000-12-07	SAMPO COMPOSITION
ID28694A (en)	2001-06-28	SAMPO COMPOSITION
DE69923810D1 (en)	2005-03-31	Hemostatic agent
DK0945132T3 (en)	2004-10-04	Ibuprofen composition
ID27415A (en)	2001-04-05	PHARMACEUTICAL COMPOSITION
ID29430A (en)	2001-08-30	HERBISIDE COMPOSITION
ATE367845T1 (en)	2007-08-15	FRAGRANCE COMPOSITIONS
ID28965A (en)	2001-07-19	AZABISIKLOALKANA AS CCR5 MODULATOR
FR2776187B1 (en)	2000-05-05	SOLID DEODORANT COMPOSITION
NO20006488D0 (en)	2000-12-19	Composition and application
ID29262A (en)	2001-08-16	PHARMACEUTICAL COMPOSITION
DK1112003T3 (en)	2003-08-04	New composition and application
DE69942892D1 (en)	2010-12-09	GAS-CREATING COMPOSITION
ID17774A (en)	1998-01-29	ANTITROMBOSIS PHARMACY COMPOSITION
ID28752A (en)	2001-06-28	SANITATION METHODS AND COMPOSITIONS
DE69930841D1 (en)	2006-05-24	DEODORANT COMPOSITION
NO20000425D0 (en)	2000-01-27	Collagen type I and type III adhesive compositions
FR2778317B1 (en)	2000-07-21	SWEETENING COMPOSITION AND USES THEREOF
DE69905519D1 (en)	2003-04-03	Block copolymer and composition containing the block copolymer

Legal Events

Date	Code	Title	Description
2000-11-10	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-12-27	17P	Request for examination filed	Effective date: 20001009
2000-12-27	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2003-11-26	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: CARITAS ST. ELIZABETH'S MEDICAL CENTER OF BOSTON,
2004-09-29	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 35/28 B Ipc: 7A 61K 35/14 B Ipc: 7A 61K 38/19 B Ipc: 7A 61K 38/18 B Ipc: 7C 12Q 1/00 B Ipc: 7A 01N 37/18 A
2004-10-06	A4	Supplementary search report drawn up and despatched	Effective date: 20040823
2006-11-02	17Q	First examination report despatched	Effective date: 20060926
2016-09-16	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2016-10-19	18D	Application deemed to be withdrawn	Effective date: 20160503