EP0964694A4 - Mucin-mediated immunomodulation - Google Patents

Mucin-mediated immunomodulation

Info

Publication number: EP0964694A4
Authority: EP; European Patent Office
Prior art keywords: mucin; mediated immunomodulation; immunomodulation; mediated
Prior art date: 1996-10-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP97946409A

Other languages

German (de)

French (fr)

Other versions

EP0964694A1 (en

Inventor

Jianlin Gong

Donald Kufe

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dana Farber Cancer Institute Inc

Original Assignee

Dana Farber Cancer Institute Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-25

Filing date

1997-10-24

Publication date

2000-09-13

1997-10-24 Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc

1999-12-22 Publication of EP0964694A1 publication Critical patent/EP0964694A1/en

2000-09-13 Publication of EP0964694A4 publication Critical patent/EP0964694A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4727—Mucins, e.g. human intestinal mucin
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Marine Sciences & Fisheries (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP97946409A 1996-10-25 1997-10-24 Mucin-mediated immunomodulation Withdrawn EP0964694A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US738262		1991-07-31
US73826296A	1996-10-25	1996-10-25
PCT/US1997/019784 WO1998017300A1 (en)	1996-10-25	1997-10-24	Mucin-mediated immunomodulation

Publications (2)

Publication Number	Publication Date
EP0964694A1 EP0964694A1 (en)	1999-12-22
EP0964694A4 true EP0964694A4 (en)	2000-09-13

Family

ID=24967271

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP97946409A Withdrawn EP0964694A4 (en)	1996-10-25	1997-10-24	Mucin-mediated immunomodulation

Country Status (4)

Country	Link
EP (1)	EP0964694A4 (en)
JP (1)	JP2001502907A (en)
CA (1)	CA2269349A1 (en)
WO (1)	WO1998017300A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998010783A1 (en) *	1996-09-10	1998-03-19	Biomira Inc.	Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions
CA2286873C (en)	1997-04-15	2010-07-13	Dana-Farber Cancer Institute, Inc.	Dendritic cell hybrids
US20050169898A1 (en)	1997-04-15	2005-08-04	Jianlin Gong	Cell fusions and methods of making and using the same
GB9904695D0 (en) *	1999-03-01	1999-04-21	Imp Cancer Res Tech	Peptide
US8031190B2 (en)	2004-05-03	2011-10-04	Microsoft Corporation	Translating two-dimensional user input on three-dimensional scene

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988005054A1 (en) *	1987-01-07	1988-07-14	Imperial Cancer Research Technology Limited	Probe
WO1995003825A1 (en) *	1993-07-30	1995-02-09	Finn Olivera J	Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
WO1998010783A1 (en) *	1996-09-10	1998-03-19	Biomira Inc.	Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions

1997
- 1997-10-24 JP JP10519748A patent/JP2001502907A/en active Pending
- 1997-10-24 EP EP97946409A patent/EP0964694A4/en not_active Withdrawn
- 1997-10-24 CA CA002269349A patent/CA2269349A1/en not_active Abandoned
- 1997-10-24 WO PCT/US1997/019784 patent/WO1998017300A1/en not_active Application Discontinuation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988005054A1 (en) *	1987-01-07	1988-07-14	Imperial Cancer Research Technology Limited	Probe
WO1995003825A1 (en) *	1993-07-30	1995-02-09	Finn Olivera J	Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
WO1998010783A1 (en) *	1996-09-10	1998-03-19	Biomira Inc.	Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ATCC catalog (web page: www.atcc.org): MDCK cells and A-375 cells MDCK cells, A-375 cells and HBL-100 cells (www.biotech.ist.unige.it) *
DENTON G ET AL: "INDUCTION OF ANTIBODY RESPONSES TO BREAST CARCINOMA ASSOCIATED MUCINS USING SYNTHETIC PEPTIDE CONSTRUCTS AS IMMUNOGENS", CANCER LETTERS,US,NEW YORK, NY, vol. 70, no. 3, 16 July 1993 (1993-07-16), pages 143 - 150, XP002035983, ISSN: 0304-3835 *
GRAHAM R A ET AL: "The polymorphic epithelial mucin: potential as an immunogen for a cancer vaccine", CANCER IMMUNOLOGY AND IMMUNOTHERAPY,DE,BERLIN, vol. 2, no. 42, 1 January 1996 (1996-01-01), pages 71 - 80, XP002075466, ISSN: 0340-7004 *
HILKENS J ET AL: "Is episialin/MUC1 involved in breast cancer progression?", CANCER LETTERS, vol. 90, no. 1, 1995, pages 27 - 33, XP000915262, ISSN: 0304-3835 *
PEAT N ET AL: "TISSUE-SPECIFIC EXPRESSION OF A HUMAN POLYMORPHIC EPITHELIAL MUCIN MUC1 IN TRANSGENIC MICE", CANCER RESEARCH, vol. 52, no. 7, 1992, pages 1954 - 1960, XP000915268, ISSN: 0008-5472 *
REDDISH MARK A ET AL: "Pre-immunotherapy serum CA27.29 (MUC-1) mucin level and CD69+ lymphocytes correlate with effects of Theratope sialyl-Tn-KLH cancer vaccine in active specific immunotherapy.", CANCER IMMUNOLOGY IMMUNOTHERAPY, vol. 42, no. 5, 1996, pages 303 - 309, XP000914873, ISSN: 0340-7004 *
See also references of WO9817300A1 *
VAN DE WIEL-VAN KEMENADE ELLY ET AL: "Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction.", JOURNAL OF IMMUNOLOGY, vol. 151, no. 2, 1993, pages 767 - 776, XP002141253, ISSN: 0022-1767 *

Also Published As

Publication number	Publication date
JP2001502907A (en)	2001-03-06
WO1998017300A1 (en)	1998-04-30
CA2269349A1 (en)	1998-04-30
EP0964694A1 (en)	1999-12-22

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Legal Events

Date	Code	Title	Description
1999-11-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-12-22	17P	Request for examination filed	Effective date: 19990525
1999-12-22	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): CH DE GB LI
2000-09-06	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 61K 38/00 A, 7A 61K 38/17 B, 7C 07K 14/47 B, 7C 07K 16/18 B
2000-09-13	A4	Supplementary search report drawn up and despatched	Effective date: 20000727
2000-09-13	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): CH DE GB LI
2001-04-04	17Q	First examination report despatched	Effective date: 20010214
2002-10-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2002-12-11	18D	Application deemed to be withdrawn	Effective date: 20020604