EP0904538A4 - Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies - Google Patents

Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Info

Publication number: EP0904538A4
Authority: EP; European Patent Office
Prior art keywords: atherosclerosis; diagnosis; treatment; cholesterol antibodies; cholesterol
Prior art date: 1995-12-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP96944237A

Other languages

German (de)

French (fr)

Other versions

EP0904538A1 (en

Inventor

Jan Dijkstra

Glenn M Swartz Jr

Jacinta Aniagolu

Carol A Nacy

Shawn J Green

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Casi Pharmaceuticals Inc

Original Assignee

Entremed Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-05

Filing date

1996-12-05

Publication date

2001-04-11

1996-12-05 Application filed by Entremed Inc filed Critical Entremed Inc

1999-03-31 Publication of EP0904538A1 publication Critical patent/EP0904538A1/en

2001-04-11 Publication of EP0904538A4 publication Critical patent/EP0904538A4/en

Status Ceased legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/323—Arteriosclerosis, Stenosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Investigating Or Analysing Biological Materials (AREA)

EP96944237A 1995-12-05 1996-12-05 Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies Ceased EP0904538A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US759569		1985-07-26
US820395P	1995-12-05	1995-12-05
US8203P		1995-12-05
US75956996A	1996-12-04	1996-12-04
PCT/US1996/019381 WO1997021099A1 (en)	1995-12-05	1996-12-05	Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Publications (2)

Publication Number	Publication Date
EP0904538A1 EP0904538A1 (en)	1999-03-31
EP0904538A4 true EP0904538A4 (en)	2001-04-11

Family

ID=26677928

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96944237A Ceased EP0904538A4 (en)	1995-12-05	1996-12-05	Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Country Status (5)

Country	Link
EP (1)	EP0904538A4 (en)
JP (1)	JP2002504225A (en)
AU (1)	AU713531B2 (en)
CA (1)	CA2239092A1 (en)
WO (1)	WO1997021099A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6492185B1 (en) *	1998-01-16	2002-12-10	Abbott Laboratories	Immunoassay for detection of very low density lipoprotein and antibodies useful therefor
AUPR458201A0 (en)	2001-04-23	2001-05-24	Commonwealth Scientific And Industrial Research Organisation	Fluid properties evaluation
WO2005023830A2 (en) *	2003-09-05	2005-03-17	The Scripps Research Institute	Ozonation products of cholesterol for the treatment and prevention of atherosclerosis and/or cardiovascular diseases
EP1668026A1 (en) *	2003-09-05	2006-06-14	The Scripps Research Institute	Detection of cholesterol ozonation products
CA2465427A1 (en) *	2004-04-28	2005-10-28	Imi International Medical Innovations Inc.	Direct assay of cholesterol in skin samples removed by tape stripping

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993018067A1 (en) *	1992-03-06	1993-09-16	Abbott Laboratories	Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
WO1994023302A1 (en) *	1993-04-07	1994-10-13	The Australian National University	Immunological assay of oxidatively modified human low density lipoproteins in plasma
EP0621284A1 (en) *	1992-08-14	1994-10-26	Shino-Test Corporation	PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994000592A1 (en) *	1992-06-26	1994-01-06	Exocell, Inc.	Monoclonal antibodies against glycated low density lipoprotein

1996
- 1996-12-05 EP EP96944237A patent/EP0904538A4/en not_active Ceased
- 1996-12-05 WO PCT/US1996/019381 patent/WO1997021099A1/en not_active Application Discontinuation
- 1996-12-05 JP JP52142997A patent/JP2002504225A/en active Pending
- 1996-12-05 CA CA 2239092 patent/CA2239092A1/en not_active Abandoned
- 1996-12-05 AU AU14097/97A patent/AU713531B2/en not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993018067A1 (en) *	1992-03-06	1993-09-16	Abbott Laboratories	Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
EP0621284A1 (en) *	1992-08-14	1994-10-26	Shino-Test Corporation	PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES
WO1994023302A1 (en) *	1993-04-07	1994-10-13	The Australian National University	Immunological assay of oxidatively modified human low density lipoproteins in plasma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9721099A1 *
SWARTZ GM ET AL: "Antibodies to cholesterol", PROC. NATL. ACAD. SCI., vol. 85, March 1988 (1988-03-01), USA, pages 1902 - 1906, XP000942042 *

Also Published As

Publication number	Publication date
AU713531B2 (en)	1999-12-02
WO1997021099A1 (en)	1997-06-12
JP2002504225A (en)	2002-02-05
CA2239092A1 (en)	1997-06-12
AU1409797A (en)	1997-06-27
EP0904538A1 (en)	1999-03-31

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Legal Events

Date	Code	Title	Description
1999-02-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-03-31	17P	Request for examination filed	Effective date: 19980612
1999-03-31	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): DE FR GB IT
2001-04-11	A4	Supplementary search report drawn up and despatched	Effective date: 20010228
2001-04-11	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): DE FR GB IT
2001-04-11	RIC1	Information provided on ipc code assigned before grant	Free format text: 7G 01N 33/53 A, 7G 01N 33/92 B
2001-08-29	17Q	First examination report despatched	Effective date: 20010713
2002-01-16	RTI1	Title (correction)	Free format text: METHOD OF DIAGNOSIS OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES
2002-01-30	RTI1	Title (correction)	Free format text: METHOD OF DIAGNOSIS OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES
2002-02-11	GRAG	Despatch of communication of intention to grant	Free format text: ORIGINAL CODE: EPIDOS AGRA
2002-02-13	RTI1	Title (correction)	Free format text: METHOD OF DIAGNOSIS OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES
2002-03-06	RTI1	Title (correction)	Free format text: METHOD OF DIAGNOSIS OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES
2002-03-13	RTI1	Title (correction)	Free format text: METHOD OF DIAGNOSIS OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES
2002-11-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2003-01-02	18R	Application refused	Effective date: 20020809