EP0904069A4 - Pla2 inhibitors of angiogenesis - Google Patents

Pla2 inhibitors of angiogenesis

Info

Publication number: EP0904069A4
Authority: EP; European Patent Office
Prior art keywords: angiogenesis; pla2 inhibitors; pla2; inhibitors
Prior art date: 1996-03-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP97917625A

Other languages

German (de)

French (fr)

Other versions

EP0904069A1 (en

Inventor

Jeffrey A Jackson

James D Winkler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-26

Filing date

1997-03-26

Publication date

2006-08-23

1997-03-26 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1999-03-31 Publication of EP0904069A1 publication Critical patent/EP0904069A1/en

2006-08-23 Publication of EP0904069A4 publication Critical patent/EP0904069A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP97917625A 1996-03-26 1997-03-26 Pla2 inhibitors of angiogenesis Withdrawn EP0904069A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1424496P	1996-03-26	1996-03-26
US14244P		1996-03-26
PCT/US1997/004876 WO1997035567A1 (en)	1996-03-26	1997-03-26	Pla2 inhibitors of angiogenesis

Publications (2)

Publication Number	Publication Date
EP0904069A1 EP0904069A1 (en)	1999-03-31
EP0904069A4 true EP0904069A4 (en)	2006-08-23

Family

ID=21764322

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP97917625A Withdrawn EP0904069A4 (en)	1996-03-26	1997-03-26	Pla2 inhibitors of angiogenesis

Country Status (3)

Country	Link
EP (1)	EP0904069A4 (en)
JP (1)	JP2000507946A (en)
WO (1)	WO1997035567A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6482802B1 (en)	1998-05-11	2002-11-19	Endowment For Research In Human Biology, Inc.	Use of neomycin for treating angiogenesis-related diseases
AUPS282602A0 (en)	2002-06-07	2002-06-27	Garvan Institute Of Medical Research	Method of inhibiting cell proliferation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995000649A1 (en) *	1993-06-25	1995-01-05	Smithkline Beecham Plc	Lipoprotein associated phospholipase a2, inhibitors thereof and use of the same in diagnosis and therapy
WO1995033461A1 (en) *	1994-06-02	1995-12-14	Smithkline Beecham Corporation	Anti-inflammatory compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1600840A (en) *	1978-05-30	1981-10-21	Wellcome Found	Diphenylether derivatives useful as flukicidal agents

1997
- 1997-03-26 JP JP9534590A patent/JP2000507946A/en not_active Ceased
- 1997-03-26 EP EP97917625A patent/EP0904069A4/en not_active Withdrawn
- 1997-03-26 WO PCT/US1997/004876 patent/WO1997035567A1/en active Application Filing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995000649A1 (en) *	1993-06-25	1995-01-05	Smithkline Beecham Plc	Lipoprotein associated phospholipase a2, inhibitors thereof and use of the same in diagnosis and therapy
WO1995033461A1 (en) *	1994-06-02	1995-12-14	Smithkline Beecham Corporation	Anti-inflammatory compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9735567A1 *

Also Published As

Publication number	Publication date
WO1997035567A1 (en)	1997-10-02
EP0904069A1 (en)	1999-03-31
JP2000507946A (en)	2000-06-27

Publication	Publication Date	Title
PL334846A1 (en)	2000-03-27	Sulphamidic inhibitors of metaloproteases
PL331856A1 (en)	1999-08-16	Heterocyclic inhibitors of metaloprotease
EP0984692A4 (en)	2001-02-21	Novel angiogenesis inhibitors
EP1017682A4 (en)	2000-11-08	Novel angiogenesis inhibitors
AP9701054A0 (en)	1997-10-31	Inhibitors of cycteine protease
PL327569A1 (en)	1998-12-21	Promedications of thrombosin inhibitors
PL329875A1 (en)	1999-04-12	Derivatives of carbolin
PL329195A1 (en)	1999-03-15	Derivatives of 6-phenylpyridol-2-amine
HU9603475D0 (en)	1997-02-28	Inhibitors of interlaukin-1beta converting enzyme
PL331338A1 (en)	1999-07-05	Thiosulphonamidic metaloprotease inhibitors
HUP9902099A3 (en)	2001-10-29	Methods and compositions useful for inhibition of angiogenesis
AU1740900A (en)	2000-06-13	Method of inhibiting angiogenesis
PL331838A1 (en)	1999-08-02	1,3-diheterocyclic inhibitors of metaloproteases
AU1271297A (en)	1997-12-09	Inhibitor of ceramidase
PL333918A1 (en)	2000-01-31	Derivatives of 6-phenylpyryidil-2-amine useful as nos inhibitors
PL316669A1 (en)	1997-04-28	Angiogenesis inhibitors
PL327998A1 (en)	1999-01-04	Novel derivatives of 19-nor-pregnene
EP1005343A4 (en)	2000-06-07	Use of csaid?tm compounds as inhibitors of angiogenesis
PL326863A1 (en)	1998-10-26	Thrombine inhibitors
PL334975A1 (en)	2000-03-27	Application of gasto-intestinal lipase inhibitors
PL331920A1 (en)	1999-08-16	Spirocyclic inhibitors of metaloproteases
PL328665A1 (en)	1999-02-15	Inhibitors of serinic protease
PL331803A1 (en)	1999-08-02	Bidonoric metaloprotease inhibitors
PL337725A1 (en)	2000-08-28	Inhibitors of proteases
AU2277597A (en)	1997-09-10	New inhibitors of sh2-mediated processes

Legal Events

Date	Code	Title	Description
1999-02-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-03-31	17P	Request for examination filed	Effective date: 19980929
1999-03-31	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE CH DE ES FR GB IT LI NL
2006-08-23	A4	Supplementary search report drawn up and despatched	Effective date: 20060725
2007-03-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-04-25	18D	Application deemed to be withdrawn	Effective date: 19971229