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EP0873789A3 - Device with reception means encapsulating materials - Google Patents

Device with reception means encapsulating materials Download PDF

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Publication number
EP0873789A3
EP0873789A3 EP98107137A EP98107137A EP0873789A3 EP 0873789 A3 EP0873789 A3 EP 0873789A3 EP 98107137 A EP98107137 A EP 98107137A EP 98107137 A EP98107137 A EP 98107137A EP 0873789 A3 EP0873789 A3 EP 0873789A3
Authority
EP
European Patent Office
Prior art keywords
cavities
reception means
encapsulating materials
means encapsulating
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98107137A
Other languages
German (de)
French (fr)
Other versions
EP0873789A2 (en
Inventor
Mathias Dipl.-Phys. Roth
Hanns-Erik Dr.-Ing. Endres
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Original Assignee
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV filed Critical Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Publication of EP0873789A2 publication Critical patent/EP0873789A2/en
Publication of EP0873789A3 publication Critical patent/EP0873789A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7135—Opening the seal between the compartments by application of heat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7137—Piercing, perforating or melting membranes or closures which seal the compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Micromachines (AREA)

Abstract

Bei einer Vorrichtung (10) zur getrennten, gekapselten Aufnahme einer Mehrzahl gleicher oder unterschiedlicher Stoffe in einer Mehrzahl von abgeschlossenen Hohlräumen (8, 10) in einer mikromechanisch gefertigten Struktur sind zumindest zwei der Hohlräume (8, 10) durch eine in Mikrosystemtechnik oder Dünnfilmtechnologie implementierte Membran (5) getrennt. Die Vorrichtung (10) weist eine elektrisch betätigbare Heizeinrichtung (7) zum Zerstören der Membran (5), um die zumindest zwei Hohlräume (8, 10) zu verbinden, auf.

Figure 00000001
In a device (10) for the separate, encapsulated holding of a plurality of identical or different substances in a plurality of closed cavities (8, 10) in a micromechanically manufactured structure, at least two of the cavities (8, 10) are implemented by a microsystem technology or thin film technology Separated membrane (5). The device (10) has an electrically actuated heating device (7) for destroying the membrane (5) in order to connect the at least two cavities (8, 10).
Figure 00000001
EP98107137A 1997-04-21 1998-04-20 Device with reception means encapsulating materials Withdrawn EP0873789A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19716683 1997-04-21
DE19716683A DE19716683C1 (en) 1997-04-21 1997-04-21 Miniature encapsulation device for sensitive materials

Publications (2)

Publication Number Publication Date
EP0873789A2 EP0873789A2 (en) 1998-10-28
EP0873789A3 true EP0873789A3 (en) 1999-09-15

Family

ID=7827208

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98107137A Withdrawn EP0873789A3 (en) 1997-04-21 1998-04-20 Device with reception means encapsulating materials

Country Status (2)

Country Link
EP (1) EP0873789A3 (en)
DE (1) DE19716683C1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070590B1 (en) 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
DE19858443A1 (en) * 1998-12-17 2000-07-06 Inst Mikrotechnik Mainz Gmbh Method for dispensing a fluid, fluidic component and device for handling such components
WO2001012157A1 (en) 1999-08-18 2001-02-22 Microchips, Inc. Thermally-activated microchip chemical delivery devices
CA2393603C (en) 1999-12-10 2010-09-21 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
AU5289001A (en) 2000-03-02 2001-09-12 Microchips Inc Microfabricated devices for the storage and selective exposure of chemicals and devices
US7226442B2 (en) 2000-10-10 2007-06-05 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
AU2002241834B2 (en) 2001-01-09 2006-11-09 Microchips, Inc. Flexible microchip devices for opthalmic and other applications
AU2002326304A1 (en) 2001-05-31 2002-12-16 Massachusetts Institute Of Technology Microchip devices with improved reservoir opening
US7318912B2 (en) * 2001-06-07 2008-01-15 Nanostream, Inc. Microfluidic systems and methods for combining discrete fluid volumes
CA2451953A1 (en) 2001-06-28 2003-04-24 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
DE10133013C2 (en) * 2001-07-06 2003-07-03 Karlsruhe Forschzent Closure for cavities or feedthroughs
JP4436258B2 (en) 2002-08-16 2010-03-24 マイクロチップス・インコーポレーテッド Controlled release device and method
AU2003278766A1 (en) 2002-09-04 2004-03-29 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
AU2003278881A1 (en) 2002-09-23 2004-04-08 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
US7599737B2 (en) 2002-10-04 2009-10-06 Microchips, Inc. Medical device for neural stimulation and controlled drug delivery
AU2003279842A1 (en) 2002-10-04 2004-05-04 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
US7332348B2 (en) 2003-02-28 2008-02-19 Applera Corporation Sample substrate having a divided sample chamber and method of loading thereof
US8095197B2 (en) 2003-11-03 2012-01-10 Microchips, Inc. Medical device for sensing glucose
WO2006015299A2 (en) 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
DE102004041941B4 (en) * 2004-08-30 2007-01-11 P.A.L.M. Microlaser Technologies Ag Method for obtaining biological objects with a recording unit
SG157362A1 (en) 2004-11-04 2009-12-29 Microchips Inc Compression and cold weld sealing methods and devices
US7413846B2 (en) 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
AU2006208131A1 (en) 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
SE529165C2 (en) * 2005-10-04 2007-05-22 Nanospace Ab A micromechanical high pressure isolation valve system
CN112337516B (en) * 2020-09-18 2022-04-29 东莞东阳光医疗智能器件研发有限公司 Air pressure balance microfluidic chip and control method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198135A (en) * 1979-04-04 1980-04-15 Polaroid Corporation Method and apparatus for releasing processing fluid from a fluid applicator by application of thermal energy
DE3520416A1 (en) * 1985-06-07 1986-12-11 Erno Raumfahrttechnik Gmbh Device for the controllable opening of a partition
US5262127A (en) * 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
WO1994025862A1 (en) * 1993-05-04 1994-11-10 Washington State University Research Foundation Biosensor substrate for mounting bilayer lipid membrane containing a receptor
WO1997021090A1 (en) * 1995-12-05 1997-06-12 Gamera Bioscience Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
DE19610293C1 (en) * 1996-03-15 1997-07-31 Fraunhofer Ges Forschung Electronically-breakable microencapsulation system for sensitive materials
FR2744803A1 (en) * 1996-02-12 1997-08-14 Bio Merieux METHOD AND DEVICE FOR PROCESSING AN ANALYSIS CARD

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3818614A1 (en) * 1988-06-01 1989-12-07 Messerschmitt Boelkow Blohm Microcontainer
DE3915920A1 (en) * 1989-05-16 1990-11-22 Messerschmitt Boelkow Blohm Micro-mechanical structures for storing and testing substances - e.g. for disease diagnosis, is made of inert material, e.g. glass, and has defined pattern of depressions, cavities, etc.
DE3919042A1 (en) * 1989-06-10 1990-12-13 Bodenseewerk Perkin Elmer Co METHOD AND DEVICE FOR ANALYZING SOLID SUBSTANCES ON MERCURY

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198135A (en) * 1979-04-04 1980-04-15 Polaroid Corporation Method and apparatus for releasing processing fluid from a fluid applicator by application of thermal energy
DE3520416A1 (en) * 1985-06-07 1986-12-11 Erno Raumfahrttechnik Gmbh Device for the controllable opening of a partition
US5262127A (en) * 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
WO1994025862A1 (en) * 1993-05-04 1994-11-10 Washington State University Research Foundation Biosensor substrate for mounting bilayer lipid membrane containing a receptor
WO1997021090A1 (en) * 1995-12-05 1997-06-12 Gamera Bioscience Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
FR2744803A1 (en) * 1996-02-12 1997-08-14 Bio Merieux METHOD AND DEVICE FOR PROCESSING AN ANALYSIS CARD
DE19610293C1 (en) * 1996-03-15 1997-07-31 Fraunhofer Ges Forschung Electronically-breakable microencapsulation system for sensitive materials

Also Published As

Publication number Publication date
EP0873789A2 (en) 1998-10-28
DE19716683C1 (en) 1998-06-04

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