EP0807165A4 - RECOMBINANT -g(a)-GALACTOSIDASE ENZYME - Google Patents

RECOMBINANT -g(a)-GALACTOSIDASE ENZYME

Info

Publication number: EP0807165A4
Authority: EP; European Patent Office
Prior art keywords: recombinant; galactosidase enzyme; galactosidase; enzyme
Prior art date: 1995-01-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP96903741A

Other languages

German (de)

French (fr)

Other versions

EP0807165A1 (en

Inventor

Alex Zhu

Jack Goldstein

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

New York Blood Center Inc

Original Assignee

New York Blood Center Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-30

Filing date

1996-01-30

Publication date

1998-07-15

1996-01-30 Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc

1997-11-19 Publication of EP0807165A1 publication Critical patent/EP0807165A1/en

1998-07-15 Publication of EP0807165A4 publication Critical patent/EP0807165A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Mycology (AREA)
Plant Pathology (AREA)
Hematology (AREA)
Cell Biology (AREA)
Developmental Biology & Embryology (AREA)
Immunology (AREA)
Virology (AREA)
Physics & Mathematics (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Enzymes And Modification Thereof (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EP96903741A 1995-01-30 1996-01-30 RECOMBINANT -g(a)-GALACTOSIDASE ENZYME Withdrawn EP0807165A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US38019495A	1995-01-30	1995-01-30
US380194		1995-01-30
PCT/US1996/001212 WO1996023869A1 (en)	1995-01-30	1996-01-30	RECOMBINANT α-GALACTOSIDASE ENZYME

Publications (2)

Publication Number	Publication Date
EP0807165A1 EP0807165A1 (en)	1997-11-19
EP0807165A4 true EP0807165A4 (en)	1998-07-15

Family

ID=23500271

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96903741A Withdrawn EP0807165A4 (en)	1995-01-30	1996-01-30	RECOMBINANT -g(a)-GALACTOSIDASE ENZYME

Country Status (5)

Country	Link
EP (1)	EP0807165A4 (en)
JP (1)	JPH10513057A (en)
AU (1)	AU4772596A (en)
CA (1)	CA2211417A1 (en)
WO (1)	WO1996023869A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6458574B1 (en) *	1996-09-12	2002-10-01	Transkaryotic Therapies, Inc.	Treatment of a α-galactosidase a deficiency
US7767415B2 (en)	2001-09-25	2010-08-03	Velico Medical, Inc.	Compositions and methods for modifying blood cell carbohydrates
CA2696699A1 (en)	2007-08-20	2009-02-26	Protalix Ltd.	Saccharide-containing protein conjugates and uses thereof
US9194011B2 (en)	2009-11-17	2015-11-24	Protalix Ltd.	Stabilized alpha-galactosidase and uses thereof
WO2011061736A1 (en) *	2009-11-17	2011-05-26	Protalix Ltd.	Alkaline alpha galactosidase for the treatment of fabry disease
SMT202000201T1 (en)	2011-01-20	2020-05-08	Protalix Ltd	Alpha-galactosidase compositions
CN114752581B (en) *	2022-04-20	2023-05-26	南京工业大学	A kind of α-galactosidase mutant and its application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1987007641A1 (en) *	1986-06-03	1987-12-17	Unilever Nv	Production of guar alpha-galactosidase by hosts transformed with recombinant dna methods
WO1994009123A1 (en) *	1992-10-22	1994-04-28	The New York Blood Center, Inc.	Recycling of enzymes used to convert sub-type a, b and ab erythrocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0438200B1 (en) *	1990-01-16	2002-07-17	Centro De Ingenieria Genetica Y Biotecnologia	Method for the expression of heterologous genes in the yeast Pichia pastoris, expression vectors and transformed microorganisms
US5330901A (en) *	1991-04-26	1994-07-19	Research Corporation Technologies, Inc.	Expression of human serum albumin in Pichia pastoris

1996
- 1996-01-30 EP EP96903741A patent/EP0807165A4/en not_active Withdrawn
- 1996-01-30 AU AU47725/96A patent/AU4772596A/en not_active Abandoned
- 1996-01-30 WO PCT/US1996/001212 patent/WO1996023869A1/en not_active Ceased
- 1996-01-30 JP JP8523663A patent/JPH10513057A/en not_active Ceased
- 1996-01-30 CA CA002211417A patent/CA2211417A1/en not_active Abandoned

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1987007641A1 (en) *	1986-06-03	1987-12-17	Unilever Nv	Production of guar alpha-galactosidase by hosts transformed with recombinant dna methods
WO1994009123A1 (en) *	1992-10-22	1994-04-28	The New York Blood Center, Inc.	Recycling of enzymes used to convert sub-type a, b and ab erythrocytes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO9623869A1 *
ZHU A ET AL: "Cloning and functional expression of a cDNA encoding coffee bean alpha-galactosidase.", GENE, MAR 25 1994, 140 (2) P227-31, NETHERLANDS, XP002062116 *
ZHU, ALEX GOLDSTEIN, JACK: "High-level expression and purification of coffee bean alpha-galactosidase produced in the yeast Pichia pastoris.", ARCH BIOCHEM BIOPHYS, DEC 1 1995, 324 (1) P65-70, UNITED STATES, XP002062117 *

Also Published As

Publication number	Publication date
EP0807165A1 (en)	1997-11-19
WO1996023869A1 (en)	1996-08-08
JPH10513057A (en)	1998-12-15
CA2211417A1 (en)	1996-08-08
AU4772596A (en)	1996-08-21

Publication	Publication Date	Title
GB2300796B (en)	1998-07-08	A falsie
GB2310195B (en)	1999-10-27	A tapeline
GB2297489B (en)	1998-10-07	A tooth-cleaner
EP0807165A4 (en)	1998-07-15	RECOMBINANT -g(a)-GALACTOSIDASE ENZYME
GB2299970B (en)	1998-04-01	A publication
GB2297894B (en)	1998-03-04	A falsie
GB9717959D0 (en)	1997-10-29	A holdall
AU129370S (en)	1997-03-10	A gameboard
AU126915S (en)	1996-06-03	A teatowel
GB9519300D0 (en)	1995-11-22	A depth-finder
ZA965287B (en)	1997-07-11	A weight-belt
AU126914S (en)	1996-06-03	A teatowel
GB9504971D0 (en)	1995-04-26	A sackbarrow
AU127143S (en)	1996-06-28	A puzzle
GB9506072D0 (en)	1995-05-10	A puzzle
ZA964739B (en)	1997-01-08	A puzzle
GB9510523D0 (en)	1995-07-19	A game
GB9611238D0 (en)	1996-07-31	A game
GB9521617D0 (en)	1996-01-03	A game
GB9516094D0 (en)	1995-10-04	A game
GB9507867D0 (en)	1995-05-31	A game
AU128488S (en)	1996-10-28	A can
AU128917S (en)	1996-12-16	A member
AU129445S (en)	1997-03-18	A figure
AUPN330195A0 (en)	1995-06-22	A puzzle

Legal Events

Date	Code	Title	Description
1997-10-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1997-11-19	17P	Request for examination filed	Effective date: 19970827
1997-11-19	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1998-06-03	RHK1	Main classification (correction)	Ipc: C12N 15/56
1998-07-15	A4	Supplementary search report drawn up and despatched	Effective date: 19980529
1998-07-15	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-12-29	RTI1	Title (correction)	Free format text: RECOMBINANT ALPHA-GALACTOSIDASE ENZYME
2001-08-22	17Q	First examination report despatched	Effective date: 20010709
2004-01-09	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2004-02-25	18D	Application deemed to be withdrawn	Effective date: 20030812