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EP0804167A4 - - Google Patents

Info

Publication number
EP0804167A4
EP0804167A4 EP93915443A EP93915443A EP0804167A4 EP 0804167 A4 EP0804167 A4 EP 0804167A4 EP 93915443 A EP93915443 A EP 93915443A EP 93915443 A EP93915443 A EP 93915443A EP 0804167 A4 EP0804167 A4 EP 0804167A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93915443A
Other versions
EP0804167A1 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of EP0804167A1 publication Critical patent/EP0804167A1/en
Publication of EP0804167A4 publication Critical patent/EP0804167A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP93915443A 1992-06-26 1993-06-22 Spheronization process using charged resins Withdrawn EP0804167A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/906,226 US5350584A (en) 1992-06-26 1992-06-26 Spheronization process using charged resins
US906226 1992-06-26
PCT/US1993/005941 WO1994000111A1 (en) 1992-06-26 1993-06-22 Spheronization process using charged resins

Publications (2)

Publication Number Publication Date
EP0804167A1 EP0804167A1 (en) 1997-11-05
EP0804167A4 true EP0804167A4 (en) 1997-11-05

Family

ID=25422115

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93915443A Withdrawn EP0804167A1 (en) 1992-06-26 1993-06-22 Spheronization process using charged resins

Country Status (9)

Country Link
US (1) US5350584A (en)
EP (1) EP0804167A1 (en)
JP (1) JP2793042B2 (en)
CN (1) CN1081877A (en)
AU (1) AU4542393A (en)
CA (1) CA2136435A1 (en)
TW (1) TW242115B (en)
WO (1) WO1994000111A1 (en)
YU (1) YU41993A (en)

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GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
GB9505032D0 (en) * 1995-03-13 1995-05-03 Westminster Lab Ltd Improvements in or relating to organic compositions
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
JPH11514382A (en) * 1995-11-02 1999-12-07 メルク フロスト カナダ アンド カンパニー New wet granulation method
WO1998025590A2 (en) * 1996-12-12 1998-06-18 Dds Drug Delivery Service Gesellschaft Zur Förderung Der Forschung In Pharmazeutischer Technologie Und Biopharmazie Mbh Preparation in form of a matrix material-auxiliary agent compound containing optionally an active substance
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
US5916595A (en) * 1997-12-12 1999-06-29 Andrx Pharmaceutials, Inc. HMG co-reductase inhibitor
US20040029962A1 (en) * 1997-12-12 2004-02-12 Chih-Ming Chen HMG-COA reductase inhibitor extended release formulation
US8679534B2 (en) * 1997-12-12 2014-03-25 Andrx Labs, Llc HMG-CoA reductase inhibitor extended release formulation
IT1298574B1 (en) * 1998-02-06 2000-01-12 Vectorpharma Int PHARMACEUTICAL COMPOSITIONS IN THE FORM OF POLYMER-BASED MICROPARTICLES OBTAINED BY EXTRUSION AND SPHERONIZATION
US7122207B2 (en) 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA69413C2 (en) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Enteric coated pharmaceutical composition, pharmaceutical composition in form of spheroid beads, method for manufacturing pharmaceutical composition
UA73092C2 (en) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Tablets with enteric coating and method for their manufacture
DE19855440A1 (en) * 1998-12-01 2000-06-08 Basf Ag Process for the production of solid dosage forms by melt extrusion
DE19918325A1 (en) 1999-04-22 2000-10-26 Euro Celtique Sa Extruded drug dosage form, e.g. granulate for tableting, comprising an active agent in a polysaccharide-containing matrix, giving a release profile which is controllable by extrusion conditions and/or the inclusion of additives
JP2003522127A (en) * 1999-07-29 2003-07-22 ロクセニ ラボラトリーズ インコーポレイテッド Opioid sustained release formulation
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US6764694B1 (en) * 1999-08-31 2004-07-20 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
DE10008506A1 (en) * 2000-02-24 2001-09-13 Bayer Ag Process for the preparation of pharmaceutical dosage forms
USRE44578E1 (en) 2000-04-10 2013-11-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
DK2382970T3 (en) * 2000-04-10 2013-03-25 Teva Pharma STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPHENIC ACIDS
CA2542968C (en) * 2003-10-20 2013-06-04 Framework Therapeutics, L.L.C. Zeolite molecular sieves for the removal of toxins
US7387793B2 (en) * 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
DE102005042875A1 (en) * 2004-12-23 2006-09-21 Grünenthal GmbH Fast-release dosage forms for antibiotics
US8318230B2 (en) * 2005-05-02 2012-11-27 Henkel Ag & Co. Kgaa Use of debranched starch in extrusion-spheronization pharmaceutical pellets
CA2578626C (en) 2005-06-27 2011-07-19 Biovail Laboratories International S.R.L. Modified-release formulations of a bupropion salt
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
BRPI0918499A2 (en) * 2008-09-02 2015-12-01 Usv Ltd cross-linked polymers
WO2012042314A1 (en) 2010-10-02 2012-04-05 Link Research & Grants Corporation Treatment of tinnitus and related auditory dysfunctions
WO2012064266A1 (en) 2010-11-04 2012-05-18 Albireo Ab Ibat inhibitors for the treatment of liver diseases
US20120308895A1 (en) 2011-05-31 2012-12-06 General Electric Company Electrode compositions useful for energy storage devices and other applications; and related devices and processes
CN106659726A (en) 2014-06-25 2017-05-10 Ea制药株式会社 Solid preparation, and method for preventing or reducing discoloration thereof
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
ES2784446T3 (en) * 2016-02-09 2020-09-25 Albireo Ab Cholestyramine microgranules and methods for their preparation
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
WO2019032027A1 (en) * 2017-08-09 2019-02-14 Albireo Ab Cholestyramine pellets, oral cholestyramine formulations and use thereof
JP2020530448A (en) 2017-08-09 2020-10-22 アルビレオ・アクチボラグ Cholestyramine granules, oral cholestyramine preparations, and their use
CN107552777A (en) * 2017-09-05 2018-01-09 昆山玛冀电子有限公司 A kind of powder particle composition and production technology for inductance production
AU2018360383A1 (en) 2017-11-02 2020-05-21 Natureceuticals Sdn. Bhd. Extract of orthosiphon stamineus, formulations, and uses thereof
TW202015699A (en) 2018-06-05 2020-05-01 瑞典商艾爾比瑞歐公司 Benzothia(di)azepine compounds and their use as bile acid modulators
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
HUE070725T2 (en) 2018-06-20 2025-06-28 Albireo Ab Crystal modifications of odevixibat
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
CA3127568A1 (en) 2019-02-06 2020-08-13 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
JP7665620B2 (en) 2019-12-04 2025-04-21 アルビレオ・アクチボラグ Benzothiadiazepine compounds and their use as bile acid modulators - Patents.com
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
AU2020397448A1 (en) 2019-12-04 2022-05-26 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
JP7696898B2 (en) 2019-12-04 2025-06-23 アルビレオ・アクチボラグ Benzothia(di)azepine compounds and their use as bile acid modulators - Patents.com
CN114761080B (en) 2019-12-04 2024-07-23 阿尔比里奥公司 Benzothia(di)azepine compounds and their use as bile acid regulators
CA3186857A1 (en) 2020-08-03 2022-02-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
EP4243831A1 (en) 2020-11-12 2023-09-20 Albireo AB Odevixibat for treating progressive familial intrahepatic cholestasis (pfic)
CN116583504A (en) 2020-12-04 2023-08-11 阿尔比里奥公司 Benzothiazepine compounds and their use as bile acid modulators

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092993A2 (en) * 1982-04-23 1983-11-02 A/S Alfred Benzon Composition for investigating alimentary functions
EP0368682A1 (en) * 1988-11-11 1990-05-16 Euroceltique S.A. Pharmaceutical ion exchange resin composition

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GB717840A (en) * 1951-09-22 1954-11-03 Ici Ltd Water-dispersible solid compositions
US3131121A (en) * 1960-10-31 1964-04-28 Hoffmann La Roche Highly acidic cation exchange resin containing amprotropine cations
CA1236023A (en) * 1984-07-18 1988-05-03 Yegnaswami Raghunathan Controlled release pharmaceutical preparations
US4663364A (en) * 1984-09-05 1987-05-05 Kao Corporation Biocidal fine powder, its manufacturing method and a suspension for agricultural use containing the above powder
US4976949A (en) * 1985-10-25 1990-12-11 The University Of Michigan Controlled release dosage form
ATE71293T1 (en) * 1986-09-18 1992-01-15 London Pharmacy Innovation DRUG FORMULATION.
US4808413A (en) * 1987-04-28 1989-02-28 E. R. Squibb & Sons, Inc. Pharmaceutical compositions in the form of beadlets and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092993A2 (en) * 1982-04-23 1983-11-02 A/S Alfred Benzon Composition for investigating alimentary functions
EP0368682A1 (en) * 1988-11-11 1990-05-16 Euroceltique S.A. Pharmaceutical ion exchange resin composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9400111A1 *

Also Published As

Publication number Publication date
CN1081877A (en) 1994-02-16
EP0804167A1 (en) 1997-11-05
YU41993A (en) 1997-01-08
JPH07508280A (en) 1995-09-14
CA2136435A1 (en) 1994-01-06
WO1994000111A1 (en) 1994-01-06
JP2793042B2 (en) 1998-09-03
TW242115B (en) 1995-03-01
AU4542393A (en) 1994-01-24
US5350584A (en) 1994-09-27

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950126

A4 Supplementary search report drawn up and despatched

Effective date: 19961021

AK Designated contracting states

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20000107