EP0748333A4 - Antithrombotic agents - Google Patents

Antithrombotic agents

Info

Publication number: EP0748333A4
Authority: EP; European Patent Office
Prior art keywords: antithrombotic agents; antithrombotic; agents
Prior art date: 1994-03-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP95911134A

Other languages

German (de)

French (fr)

Other versions

EP0748333A1 (en

Inventor

Aaron Leigh Schacht

Robert Theodore Shuman

Gerald Floyd Smith

James Howard Wikel

Michael Robert Wiley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-04

Filing date

1995-03-03

Publication date

2000-05-10

1994-10-05 Priority claimed from US08/318,600 external-priority patent/US5602101A/en

1995-03-03 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1996-12-18 Publication of EP0748333A1 publication Critical patent/EP0748333A1/en

2000-05-10 Publication of EP0748333A4 publication Critical patent/EP0748333A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

EP95911134A 1994-03-04 1995-03-03 Antithrombotic agents Withdrawn EP0748333A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US20650094A	1994-03-04	1994-03-04
US206500		1994-03-04
US318600		1994-10-05
US08/318,600 US5602101A (en)	1994-03-04	1994-10-05	Antithrombotic agents
PCT/US1995/002627 WO1995023809A1 (en)	1994-03-04	1995-03-03	Antithrombotic agents

Publications (2)

Publication Number	Publication Date
EP0748333A1 EP0748333A1 (en)	1996-12-18
EP0748333A4 true EP0748333A4 (en)	2000-05-10

Family

ID=26901406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP95911134A Withdrawn EP0748333A4 (en)	1994-03-04	1995-03-03	Antithrombotic agents

Country Status (5)

Country	Link
EP (1)	EP0748333A4 (en)
JP (1)	JPH09509943A (en)
AU (1)	AU1884395A (en)
CA (1)	CA2184188A1 (en)
WO (1)	WO1995023809A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7655796A (en) *	1995-11-30	1997-06-19	C & C Research Laboratories	Sulfamide derivatives
DE19549118C2 (en) *	1995-12-29	2000-07-13	Thomas W Stief	Hemostasis activation inhibitor and method for inhibiting hemostasis activation in blood or other biological fluids
IL147696A0 (en) *	2001-01-25	2002-08-14	Pfizer Prod Inc	Combination therapy
MXPA04001534A (en) *	2001-08-21	2004-11-22	Ivax Drug Res Inst Ltd	Peptide arginals and methods for treating disseminated intravascular coagulation.
WO2004022549A1 (en) *	2002-09-09	2004-03-18	Ono Pharmaceutical Co., Ltd.	Process for producing 4-methyl-1,3-thiazol-2-ylsulfonyl halide

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0479489A2 (en) *	1990-09-28	1992-04-08	Eli Lilly And Company	Tripeptide antithrombotic agents
EP0526877A2 (en) *	1991-08-06	1993-02-10	Bristol-Myers Squibb Company	Peptide aldehydes as antithrombotic agents
EP0542525A2 (en) *	1991-11-12	1993-05-19	Eli Lilly And Company	Antithrombotic agents
US5250660A (en) *	1991-11-12	1993-10-05	Eli Lilly And Company	Peptide purification process
EP0643073A1 (en) *	1993-09-14	1995-03-15	Eli Lilly And Company	Tripeptide antithrombotic agents

1995
- 1995-03-03 CA CA002184188A patent/CA2184188A1/en not_active Abandoned
- 1995-03-03 JP JP7523040A patent/JPH09509943A/en active Pending
- 1995-03-03 AU AU18843/95A patent/AU1884395A/en not_active Abandoned
- 1995-03-03 EP EP95911134A patent/EP0748333A4/en not_active Withdrawn
- 1995-03-03 WO PCT/US1995/002627 patent/WO1995023809A1/en active Search and Examination

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0479489A2 (en) *	1990-09-28	1992-04-08	Eli Lilly And Company	Tripeptide antithrombotic agents
EP0526877A2 (en) *	1991-08-06	1993-02-10	Bristol-Myers Squibb Company	Peptide aldehydes as antithrombotic agents
EP0542525A2 (en) *	1991-11-12	1993-05-19	Eli Lilly And Company	Antithrombotic agents
US5250660A (en) *	1991-11-12	1993-10-05	Eli Lilly And Company	Peptide purification process
EP0643073A1 (en) *	1993-09-14	1995-03-15	Eli Lilly And Company	Tripeptide antithrombotic agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9523809A1 *

Also Published As

Publication number	Publication date
EP0748333A1 (en)	1996-12-18
WO1995023809A1 (en)	1995-09-08
CA2184188A1 (en)	1995-09-08
AU1884395A (en)	1995-09-18
JPH09509943A (en)	1997-10-07

Publication	Publication Date	Title
IL133621A0 (en)	2001-04-30	Antithrombotic agents
IL133625A0 (en)	2001-04-30	Antithrombotic agents
GB9420657D0 (en)	1994-11-30	Contrast agents
DE59503739D1 (en)	1998-10-29	Polymer-sensor
DE69502271D1 (en)	1998-06-04	Afterabtrennung
DE69429543D1 (en)	2002-01-31	Koagulationszange
ZA951232B (en)	1996-01-22	Contrast agents
DE59503634D1 (en)	1998-10-22	Friercontainer
GB9504331D0 (en)	1995-04-19	Antithrombotic agents
ZA951618B (en)	1996-08-27	Antithrombotic agents
DE59509661D1 (en)	2001-11-08	Heterocyclylbenzonitrile
EP0748333A4 (en)	2000-05-10	Antithrombotic agents
AU122938S (en)	1995-03-06	Breadbox
EP0980367A4 (en)	2003-03-19	Antithrombotic agents
ZA955734B (en)	1996-05-29	Fitting
ZA951615B (en)	1996-08-27	Antithrombotic agents
EP0973517A4 (en)	2002-07-24	Antithrombotic agents
DE59508136D1 (en)	2000-05-11	Phenylthio-oxazolin-derivate
GB2286644A8 (en)	1995-09-18	Connection
EP0993300A4 (en)	2002-07-31	Antithrombotic agents
DE59510739D1 (en)	2003-08-07	N-cyanoaryl-stickstoffheterocyclen
DE69502834D1 (en)	1998-07-09	Vinylperfluorcyclopropanpolymere
DE59503452D1 (en)	1998-10-08	Piezoresistiver widerstand
GB9425739D0 (en)	1995-02-22	Immunopotentiary agents
CA73835S (en)	1994-01-27	Air-purifier

Legal Events

Date	Code	Title	Description
1996-11-01	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-12-18	17P	Request for examination filed	Effective date: 19960830
1996-12-18	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1996-12-18	AX	Request for extension of the european patent	Free format text: LT PAYMENT 960830;SI PAYMENT 960830
2000-05-10	A4	Supplementary search report drawn up and despatched	Effective date: 20000328
2000-05-10	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
2004-01-21	17Q	First examination report despatched	Effective date: 20031209
2004-02-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2004-04-07	18D	Application deemed to be withdrawn	Effective date: 20031001