EP0730466A4 - Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites - Google Patents
Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoitesInfo
- Publication number
- EP0730466A4 EP0730466A4 EP94928067A EP94928067A EP0730466A4 EP 0730466 A4 EP0730466 A4 EP 0730466A4 EP 94928067 A EP94928067 A EP 94928067A EP 94928067 A EP94928067 A EP 94928067A EP 0730466 A4 EP0730466 A4 EP 0730466A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- inhibiting hepatocyte
- hepatocyte invasion
- sporozoites
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000003494 hepatocyte Anatomy 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000009545 invasion Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 210000003046 sporozoite Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11969493A | 1993-09-10 | 1993-09-10 | |
US119694 | 1993-09-10 | ||
PCT/US1994/010186 WO1995007094A1 (en) | 1993-09-10 | 1994-09-09 | Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0730466A1 EP0730466A1 (en) | 1996-09-11 |
EP0730466A4 true EP0730466A4 (en) | 1999-04-14 |
Family
ID=22385814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94928067A Withdrawn EP0730466A4 (en) | 1993-09-10 | 1994-09-09 | Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0730466A4 (en) |
AU (1) | AU7724894A (en) |
CA (1) | CA2171562A1 (en) |
WO (1) | WO1995007094A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9266930B1 (en) | 1993-03-05 | 2016-02-23 | Epimmune Inc. | Inducing cellular immune responses to Plasmodium falciparum using peptide and nucleic acid compositions |
FR2840220A1 (en) * | 2002-05-28 | 2003-12-05 | Univ Paris Curie | METHOD FOR THE PROPHYLACTIC TREATMENT OF MALARIA, OR PROCESS FOR THE PREPARATION OF A MEDICAMENT FOR THE PROPHYLACTIC TREATMENT OF MALARIA |
AU2004309380B2 (en) | 2003-12-19 | 2010-04-29 | Seattle Biomedical Research Institute | Live genetically attenuated malaria vaccine |
US8168166B2 (en) | 2003-12-19 | 2012-05-01 | Seattle Biomedical Research Institute | Live genetically attenuated malaria vaccine |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0432965A1 (en) * | 1989-12-08 | 1991-06-19 | Smithkline Beecham Corporation | Malaria vaccine |
EP0517182A1 (en) * | 1991-06-03 | 1992-12-09 | Mitsubishi Chemical Corporation | Hepatocyte-growth agent |
WO1993003057A1 (en) * | 1991-07-31 | 1993-02-18 | Institut Pasteur | Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions |
WO1993002704A1 (en) * | 1991-07-31 | 1993-02-18 | Institut Pasteur | Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum |
EP0578342A2 (en) * | 1992-05-14 | 1994-01-12 | W.R. Grace & Co.-Conn. | Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor |
WO1994006464A1 (en) * | 1992-09-17 | 1994-03-31 | New York University | Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites |
-
1994
- 1994-09-09 WO PCT/US1994/010186 patent/WO1995007094A1/en not_active Application Discontinuation
- 1994-09-09 EP EP94928067A patent/EP0730466A4/en not_active Withdrawn
- 1994-09-09 AU AU77248/94A patent/AU7724894A/en not_active Abandoned
- 1994-09-09 CA CA002171562A patent/CA2171562A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0432965A1 (en) * | 1989-12-08 | 1991-06-19 | Smithkline Beecham Corporation | Malaria vaccine |
EP0517182A1 (en) * | 1991-06-03 | 1992-12-09 | Mitsubishi Chemical Corporation | Hepatocyte-growth agent |
WO1993003057A1 (en) * | 1991-07-31 | 1993-02-18 | Institut Pasteur | Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions |
WO1993002704A1 (en) * | 1991-07-31 | 1993-02-18 | Institut Pasteur | Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum |
EP0578342A2 (en) * | 1992-05-14 | 1994-01-12 | W.R. Grace & Co.-Conn. | Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor |
WO1994006464A1 (en) * | 1992-09-17 | 1994-03-31 | New York University | Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites |
Non-Patent Citations (3)
Title |
---|
CERAMI, CARLA ET AL: "The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites", CELL (CAMBRIDGE, MASS.) (1992), 70(6), 1021-33 CODEN: CELLB5;ISSN: 0092-8674, 1992, XP002090186 * |
See also references of WO9507094A1 * |
SINNIS, PHOTINI ET AL: "Structural and functional properties of region II-plus of the malaria circumsporozoite protein", J. EXP. MED. (1994), 180(1), 297-306 CODEN: JEMEAV;ISSN: 0022-1007, 1994, XP002090187 * |
Also Published As
Publication number | Publication date |
---|---|
AU7724894A (en) | 1995-03-27 |
EP0730466A1 (en) | 1996-09-11 |
WO1995007094A1 (en) | 1995-03-16 |
CA2171562A1 (en) | 1995-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19960410 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE CH DE DK ES FR GB IT LI NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19990225 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): BE CH DE DK ES FR GB IT LI NL SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20000331 |