EP0677063A4 - A NEW CLASS OF RPTPases: YOUR STRUCTURAL DOMAINS AND LIGANDS. - Google Patents

A NEW CLASS OF RPTPases: YOUR STRUCTURAL DOMAINS AND LIGANDS.

Info

Publication number: EP0677063A4
Authority: EP; European Patent Office
Prior art keywords: rptpases; ligands; new class; structural domains; domains
Prior art date: 1992-10-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93924934A

Other languages

German (de)

French (fr)

Other versions

EP0677063A1 (en

Inventor

Joseph Schlessinger

Gilad Barnea

Martin H Grumet

Richard U Margolis

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

New York University Langone Medical Center

Original Assignee

New York University Langone Medical Center

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-15

Filing date

1993-10-14

Publication date

1997-05-21

1993-10-14 Application filed by New York University Langone Medical Center filed Critical New York University Langone Medical Center

1995-10-18 Publication of EP0677063A1 publication Critical patent/EP0677063A1/en

1997-05-21 Publication of EP0677063A4 publication Critical patent/EP0677063A4/en

Status Withdrawn legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4725—Proteoglycans, e.g. aggreccan
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Hematology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Urology & Nephrology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
General Engineering & Computer Science (AREA)
Cell Biology (AREA)
Biophysics (AREA)
Toxicology (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)

EP93924934A 1992-10-15 1993-10-14 A NEW CLASS OF RPTPases: YOUR STRUCTURAL DOMAINS AND LIGANDS. Withdrawn EP0677063A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US96123592A	1992-10-15	1992-10-15
PCT/US1993/009838 WO1994009037A1 (en)	1992-10-15	1993-10-14	A NEW CLASS OF RPTPases: THEIR STRUCTURAL DOMAINS AND LIGANDS
US961235		1997-10-30

Publications (2)

Publication Number	Publication Date
EP0677063A1 EP0677063A1 (en)	1995-10-18
EP0677063A4 true EP0677063A4 (en)	1997-05-21

Family

ID=25504220

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93924934A Withdrawn EP0677063A4 (en)	1992-10-15	1993-10-14	A NEW CLASS OF RPTPases: YOUR STRUCTURAL DOMAINS AND LIGANDS.

Country Status (6)

Country	Link
EP (1)	EP0677063A4 (en)
JP (1)	JPH08502487A (en)
AU (1)	AU5443394A (en)
CA (1)	CA2147167A1 (en)
NZ (1)	NZ257713A (en)
WO (1)	WO1994009037A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6682905B1 (en)	1990-07-11	2004-01-27	New York University	Receptor-type phosphotyrosine phosphatase-alpha
US20050032087A1 (en)	1990-07-11	2005-02-10	New York University	Novel receptor-type phosphotyrosine phosphatase-alpha
US5604094A (en) *	1990-07-11	1997-02-18	New York University	Receptor-type phosphotyrosine phosphatase-β
US5766922A (en) *	1995-05-26	1998-06-16	Sugen, Inc.	Functional ligands for the axonal cell rcognition molecule contactin
AU3371099A (en) *	1998-03-30	1999-10-18	President And Fellows Of Harvard College	Regulation of glycosaminoglycan synthesis, methods and reagents related thereto
EP3796977A4 (en) *	2018-05-17	2022-03-02	The Board of Trustees of the Leland Stanford Junior University	Receptor inhibition by phosphatase recruitment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0538401B1 (en) *	1990-07-11	1999-07-28	New York University	Novel receptor-type phosphotyrosine phosphatase

1993
- 1993-10-14 EP EP93924934A patent/EP0677063A4/en not_active Withdrawn
- 1993-10-14 JP JP6510272A patent/JPH08502487A/en active Pending
- 1993-10-14 CA CA002147167A patent/CA2147167A1/en not_active Abandoned
- 1993-10-14 WO PCT/US1993/009838 patent/WO1994009037A1/en not_active Application Discontinuation
- 1993-10-14 AU AU54433/94A patent/AU5443394A/en not_active Abandoned
- 1993-10-14 NZ NZ257713A patent/NZ257713A/en unknown

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
G. BARNEA ET AL.: "Identification of a carbonic anhydrase-like domain in the extracellular region of RPTPgamma defines a new subfamily of receptor tyrosine phosphatases", MOLECULAR AND CELLULAR BIOLOGY, vol. 13, no. 3, March 1993 (1993-03-01), WASHINGTON US, pages 1497 - 1506, XP000645723 *
J.B. LEVY ET AL.: "The cloning of a receptor-type Protein Tyrosine Phosphatase expressed in the central nervous system", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 14, 15 May 1993 (1993-05-15), MD US, pages 10573 - 10581, XP002027169 *
MARTIN GRUMET ET AL.: "Functional characterization of Chondroitin Sulfate Proteoglycans of brain: Interactions with neurons and neural cell adhesion molecules", THE JOURNAL OF CELL BIOLOGY, vol. 120, no. 3, February 1993 (1993-02-01), pages 815 - 824, XP000645732 *
NEIL X. KRUEGER ET AL.: "A human transmembrane protein-tyrosine-phosphatase gamma, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 89, no. 16, 15 August 1992 (1992-08-15), WASHINGTON US, pages 7417 - 7421, XP002027168 *
See also references of WO9409037A1 *

Also Published As

Publication number	Publication date
JPH08502487A (en)	1996-03-19
EP0677063A1 (en)	1995-10-18
NZ257713A (en)	1996-10-28
CA2147167A1 (en)	1994-04-28
AU5443394A (en)	1994-05-09
WO1994009037A1 (en)	1994-04-28

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Legal Events

Date	Code	Title	Description
1995-09-01	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-10-18	17P	Request for examination filed	Effective date: 19950512
1995-10-18	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1997-05-21	A4	Supplementary search report drawn up and despatched	Effective date: 19970407
1997-05-21	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-09-24	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1999-11-10	18D	Application deemed to be withdrawn	Effective date: 19990501