EP0644933A4 - Constitutive and inducible epidermal vector systems. - Google Patents

Constitutive and inducible epidermal vector systems.

Info

Publication number: EP0644933A4
Authority: EP; European Patent Office
Prior art keywords: constitutive; vector systems; inducible; inducible epidermal; epidermal vector
Prior art date: 1992-04-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93910875A

Other languages

German (de)

French (fr)

Other versions

EP0644933A1 (en

Inventor

Dennis R Roop

Joseph A Rothnagel

David A Greenhalgh

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Baylor College of Medicine

Original Assignee

Baylor College of Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-30

Filing date

1993-04-28

Publication date

1997-06-25

1993-04-28 Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine

1995-03-29 Publication of EP0644933A1 publication Critical patent/EP0644933A1/en

1997-06-25 Publication of EP0644933A4 publication Critical patent/EP0644933A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/32—Vector systems having a special element relevant for transcription being an silencer not forming part of the promoter region
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Eye Examination Apparatus (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Superconductors And Manufacturing Methods Therefor (AREA)

EP93910875A 1992-04-30 1993-04-28 Constitutive and inducible epidermal vector systems. Withdrawn EP0644933A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US87628692A	1992-04-30	1992-04-30
US876286		1992-04-30
PCT/US1993/003993 WO1993022431A1 (en)	1992-04-30	1993-04-28	Constitutive and inducible epidermal vector systems

Publications (2)

Publication Number	Publication Date
EP0644933A1 EP0644933A1 (en)	1995-03-29
EP0644933A4 true EP0644933A4 (en)	1997-06-25

Family

ID=25367356

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93910875A Withdrawn EP0644933A4 (en)	1992-04-30	1993-04-28	Constitutive and inducible epidermal vector systems.

Country Status (5)

Country	Link
EP (1)	EP0644933A4 (en)
JP (1)	JPH08501202A (en)
AU (1)	AU669713B2 (en)
CA (1)	CA2134670A1 (en)
WO (1)	WO1993022431A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2152753B1 (en) *	1993-03-29	2001-09-01	Ct Investig Energeticas Ciemat	TRANSGENIC ANIMALS FOR THE DETERMINATION OF AGENTS THAT STIMULATE OR REPRESSE EPIDERMIC HYPERPROLIFERATION AND HAIR GROWTH
AUPM746694A0 (en) *	1994-08-15	1994-09-08	Garvan Institute Of Medical Research	Expression vector
US6187993B1 (en) *	1995-02-25	2001-02-13	Imperial Cancer Research Technology Limited	Transgenic animals as model of psoriasis
US6147056A (en) *	1995-06-06	2000-11-14	Trustees Of Boston University	Use of locally applied DNA fragments
US20030032610A1 (en)	1996-06-03	2003-02-13	Gilchrest Barbara A.	Method to inhibit cell growth using oligonucleotides
US5955059A (en) *	1995-06-06	1999-09-21	Trustees Of Boston University	Use of locally applied DNA fragments
US7094766B1 (en)	1995-06-06	2006-08-22	Trustees Of Boston University	Use of locally applied DNA fragments
GB2324960A (en) *	1997-05-09	1998-11-11	Univ Manchester	Delivery of naked DNA for wound healing
AU2001251115A1 (en)	2000-03-31	2001-10-15	Trustees Of Boston University	Use of locally applied dna fragments
US11135269B2 (en)	2013-12-11	2021-10-05	The General Hospital Corporation	Use of mullerian inhibiting substance (MIS) proteins for contraception and ovarian reserve preservation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4863899A (en) *	1983-05-09	1989-09-05	Todaro George J	Biologically active polypeptides
ATE79138T1 (en) *	1985-04-04	1992-08-15	Univ Georgetown	TYPE-SPECIFIC PAPILLOMAVIRUS DNA SEQUENCES AND PEPTIDES.
US4806523A (en) *	1985-08-06	1989-02-21	Collagen Corporation	Method of treating inflammation
US4816464A (en) *	1987-06-22	1989-03-28	American Home Products Corporation	10-Substituted benzo[b][1,6]naphthyridines as inhibitors of interleukin 1
US5024841A (en) *	1988-06-30	1991-06-18	Collagen Corporation	Collagen wound healing matrices and process for their production
JPH02109966A (en) *	1988-10-20	1990-04-23	Kirin Brewery Co Ltd	Radial flow packed bed-type bioreactor
US5087617A (en) *	1989-02-15	1992-02-11	Board Of Regents, The University Of Texas System	Methods and compositions for treatment of cancer using oligonucleotides

1993
- 1993-04-28 WO PCT/US1993/003993 patent/WO1993022431A1/en not_active Application Discontinuation
- 1993-04-28 AU AU42213/93A patent/AU669713B2/en not_active Ceased
- 1993-04-28 JP JP5519487A patent/JPH08501202A/en active Pending
- 1993-04-28 EP EP93910875A patent/EP0644933A4/en not_active Withdrawn
- 1993-04-28 CA CA002134670A patent/CA2134670A1/en not_active Abandoned

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
PNAS, vol. 81, 1984, WASHINGTON US, pages 5709 - 5713 *
ROTHNAGEL J A ET AL: "A KERATIN K6 TRANSGENE IS EXPRESSED CORRECTLY DURING DEVELOPMENT DIFFERENTIATION AND HYPERPROLIFERATION", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 100, no. 4, 28 April 1993 (1993-04-28), pages 499, XP000613621 *
ROTHNAGEL J A ET AL: "TARGETING GENE EXPRESSION TO THE EPIDERMIS OF TRANSGENIC MICE: POTENTIAL APPLICATIONS TO GENETIC SKIN DISORDERS", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 95, November 1990 (1990-11-01), pages 59S - 61S, XP000612194 *
ROTHNALGEL J A ET AL: "CHARACTERIZATION OF KERATIN K6 GENE EXPRESSION USING TRANSGENIC MICE", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 101, no. 3, September 1993 (1993-09-01), pages 427, XP000613629 *
See also references of WO9322431A1 *

Also Published As

Publication number	Publication date
AU4221393A (en)	1993-11-29
WO1993022431A1 (en)	1993-11-11
EP0644933A1 (en)	1995-03-29
JPH08501202A (en)	1996-02-13
AU669713B2 (en)	1996-06-20
CA2134670A1 (en)	1993-11-11

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GB9404819D0 (en)	1994-04-27	Multitask control system
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EP0625693A3 (en)	1996-03-27	Vertical reference and attitude system.
EP0608546A3 (en)	1995-09-27	Glia activating factor (gaf), antibodies against it and their uses.
GB9321055D0 (en)	1993-12-01	Mooring systems
EP0644933A4 (en)	1997-06-25	Constitutive and inducible epidermal vector systems.
GB2274230B (en)	1996-05-15	Communication systems
PL308148A1 (en)	1995-07-24	Latching system
GB2393056B (en)	2004-09-01	Tracking systems
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ZA941376B (en)	1994-09-27	Antenna system
GB2266108B (en)	1995-07-05	Diverter system
GB9312729D0 (en)	1993-08-04	Antenna system

Legal Events

Date	Code	Title	Description
1995-02-10	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-03-29	17P	Request for examination filed	Effective date: 19941129
1995-03-29	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1997-02-12	RHK1	Main classification (correction)	Ipc: C12N 15/85
1997-03-12	RHK1	Main classification (correction)	Ipc: C12N 15/00
1997-06-25	A4	Supplementary search report drawn up and despatched	Effective date: 19970506
1997-06-25	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
2000-02-02	17Q	First examination report despatched	Effective date: 19991220
2002-02-08	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2002-03-27	18D	Application deemed to be withdrawn	Effective date: 20010807