EP0640096A4 - Universal coronavirus vaccine. - Google Patents

Universal coronavirus vaccine.

Info

Publication number: EP0640096A4
Authority: EP; European Patent Office
Prior art keywords: universal; coronavirus vaccine; coronavirus; vaccine; universal coronavirus
Prior art date: 1992-05-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93911170A

Other languages

German (de)

French (fr)

Other versions

EP0640096A1 (en

Inventor

Timothy J Miller

Sharon Klepfer

Albert Paul Reed

Elaine V Jones

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-08

Filing date

1993-05-07

Publication date

1997-01-15

1993-05-07 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1995-03-01 Publication of EP0640096A1 publication Critical patent/EP0640096A1/en

1997-01-15 Publication of EP0640096A4 publication Critical patent/EP0640096A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

EP93911170A 1992-05-08 1993-05-07 Universal coronavirus vaccine. Withdrawn EP0640096A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US88217192A	1992-05-08	1992-05-08
US882171		1992-05-08
PCT/US1993/004365 WO1993023421A1 (en)	1992-05-08	1993-05-07	Universal coronavirus vaccine

Publications (2)

Publication Number	Publication Date
EP0640096A1 EP0640096A1 (en)	1995-03-01
EP0640096A4 true EP0640096A4 (en)	1997-01-15

Family

ID=25380027

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP93911185A Withdrawn EP0640097A4 (en)	1992-05-08	1993-05-07	Compositions and methods for vaccination against coronaviruses.
EP93911170A Withdrawn EP0640096A4 (en)	1992-05-08	1993-05-07	Universal coronavirus vaccine.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP93911185A Withdrawn EP0640097A4 (en)	1992-05-08	1993-05-07	Compositions and methods for vaccination against coronaviruses.

Country Status (5)

Country	Link
EP (2)	EP0640097A4 (en)
JP (2)	JPH08501931A (en)
AU (2)	AU678971B2 (en)
CA (2)	CA2135201A1 (en)
WO (2)	WO1993023421A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5612487A (en) *	1991-08-26	1997-03-18	Edible Vaccines, Inc.	Anti-viral vaccines expressed in plants
US6034298A (en) *	1991-08-26	2000-03-07	Prodigene, Inc.	Vaccines expressed in plants
US5484719A (en)	1991-08-26	1996-01-16	Edible Vaccines, Inc.	Vaccines produced and administered through edible plants
CA2135200C (en) *	1992-05-08	2001-03-27	Timothy J. Miller	Canine coronavirus s gene and uses therefor
AU678971B2 (en) *	1992-05-08	1997-06-19	Pfizer Inc.	Compositions and methods for vaccination against coronaviruses
AU721367B2 (en) *	1993-02-26	2000-06-29	Wyeth Holdings Corporation	Canine coronavirus vaccine from feline enteric coronavirus
EP0612532A3 (en) *	1993-02-26	1998-02-04	Solvay Animal Health, Inc.	Canine coronavirus vaccine from feline enteric coronavirus
GB2282601B (en) *	1993-09-16	1998-04-15	Solvay	Antigenically-active proteins/polypeptides and coronavirus vaccines containing the same
FR2724385B1 (en) *	1994-08-29	1996-12-13	Rhone Merieux	FELINE INFECTIOUS PERITONITIS VACCINE.
AU6976296A (en) *	1995-09-15	1997-04-01	John A Howard	Expression cassettes and methods for delivery of animal vaccines
WO1998027433A1 (en) *	1996-12-18	1998-06-25	Engene Biotechnologies, Inc	A specific diagnostic for antibodies to feline infectious peritonitis virus
WO1999025838A1 (en) *	1997-11-14	1999-05-27	University Of Georgia Research Foundation, Inc.	Compositions and methods to prevent turkey enteritis
WO2001009290A2 (en) *	1999-07-30	2001-02-08	Laboratorio Avi-Mex, S.A. De C.V.	Avian infectious bronchitis virus serotype
FR2828405B1 (en) *	2001-08-09	2005-06-24	Virbac Sa	ANTI-CORONAVIRUS VACCINE
WO2005010034A1 (en) *	2003-07-21	2005-02-03	Government Of The United States Of America As Represented By The Sercretary Of The Department Of Health And Human Services National Institutes Of Health	Soluble fragments of the sars-cov spike glycoprotein
US7605135B2 (en) *	2003-11-10	2009-10-20	The University Of Hong Kong	Baicalin as a treatment for SARS infection
ITMI20111182A1 (en)	2011-06-28	2012-12-29	Canio Buonavoglia	VACCINE FOR CORONAVIRUS CANINO
WO2015143335A1 (en) *	2014-03-20	2015-09-24	The University Of North Carolina At Chapel Hill	Methods and compositions for chimeric coronavirus spike proteins
CN113248576A (en) *	2020-02-12	2021-08-13	北京科兴中维生物技术有限公司	Nucleic acid vaccine for coronavirus and preparation method thereof
WO2022020815A1 (en) *	2020-07-24	2022-01-27	Soligenix, Inc.	Antibody/adjuvant compositions and methods of immune response generation against coronaviruses
CN113072626B (en) *	2021-04-25	2023-05-05	龙岩学院	Cat coronavirus S recombinant protein and preparation method thereof
CN113238048B (en) *	2021-05-11	2024-03-15	抗码(苏州)生物科技有限公司	Diagnostic markers and their use in differentiating between new coronavirus infection and new coronavirus inactivated vaccination
CN113861278B (en) *	2021-06-18	2022-08-05	国药中生生物技术研究院有限公司	Novel recombinant coronavirus RBD trimer protein vaccine capable of generating broad-spectrum cross-neutralization activity, and preparation method and application thereof
CN114478716B (en) *	2021-12-28	2024-05-28	梅州市人民医院(梅州市医学科学院)	Polypeptide combination and application thereof in novel coronavirus antibody detection
CN114773487B (en) *	2022-05-31	2024-07-02	湖南大学	Influenza virus and novel coronavirus fusion recombinant protein vaccine immunogen and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991002752A1 (en) *	1989-08-22	1991-03-07	Veterinary Infectious Disease Organization	Bovine coronavirus polypeptides and vaccines
WO1993023422A1 (en) *	1992-05-08	1993-11-25	Smithkline Beecham Corporation	Compositions and methods for vaccination against coronaviruses
WO1993023423A1 (en) *	1992-05-08	1993-11-25	Smithkline Beecham Corporation	Canine coronavirus s gene and uses therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0264979A1 (en) *	1986-09-05	1988-04-27	Duphar International Research B.V	New antigenically active proteins and peptides, and feline infectious peritonitis virus (FIPV) vaccines
CA2005291C (en) *	1988-12-30	1999-01-26	Beverly Dale	Feline infectious peritonitis virus diagnostic tools
NZ240558A (en) *	1990-11-14	1994-11-25	Smithkline Beecham Corp	Recombinant feline coronavirus s proteins useful in diagnosis and vaccination against feline peritonitis virus disease

1993
- 1993-05-07 AU AU42410/93A patent/AU678971B2/en not_active Ceased
- 1993-05-07 EP EP93911185A patent/EP0640097A4/en not_active Withdrawn
- 1993-05-07 WO PCT/US1993/004365 patent/WO1993023421A1/en not_active Application Discontinuation
- 1993-05-07 EP EP93911170A patent/EP0640096A4/en not_active Withdrawn
- 1993-05-07 JP JP6503668A patent/JPH08501931A/en active Pending
- 1993-05-07 AU AU42404/93A patent/AU678970B2/en not_active Ceased
- 1993-05-07 CA CA002135201A patent/CA2135201A1/en not_active Abandoned
- 1993-05-07 CA CA002134898A patent/CA2134898A1/en not_active Abandoned
- 1993-05-07 WO PCT/US1993/004384 patent/WO1993023422A1/en not_active Application Discontinuation
- 1993-05-07 JP JP6503657A patent/JPH07508176A/en active Pending

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991002752A1 (en) *	1989-08-22	1991-03-07	Veterinary Infectious Disease Organization	Bovine coronavirus polypeptides and vaccines
WO1993023422A1 (en) *	1992-05-08	1993-11-25	Smithkline Beecham Corporation	Compositions and methods for vaccination against coronaviruses
WO1993023423A1 (en) *	1992-05-08	1993-11-25	Smithkline Beecham Corporation	Canine coronavirus s gene and uses therefor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J.G. WESSELING ET AL: "Nucleotide sequence and expression of the spike (S) gene of canine coronavirrus and comparison with the S proteins of feline and porcine coronaviruses", JOURNAL OF GENERAL VIROLOGY, vol. 75, 1994, pages 1789 - 1794, XP002015276 *
P. BRITTON: "Coronavirus motif", NATURE, vol. 353, 1990, pages 394 - 394, XP002016107 *
See also references of WO9323421A1 *

Also Published As

Publication number	Publication date
WO1993023421A1 (en)	1993-11-25
WO1993023422A1 (en)	1993-11-25
CA2134898A1 (en)	1993-11-25
JPH08501931A (en)	1996-03-05
AU4240493A (en)	1993-12-13
EP0640096A1 (en)	1995-03-01
JPH07508176A (en)	1995-09-14
AU4241093A (en)	1993-12-13
AU678971B2 (en)	1997-06-19
CA2135201A1 (en)	1993-11-25
EP0640097A4 (en)	1997-01-15
AU678970B2 (en)	1997-06-19
EP0640097A1 (en)	1995-03-01

Publication	Publication Date	Title
EP0640096A4 (en)	1997-01-15	Universal coronavirus vaccine.
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GB9325496D0 (en)	1994-02-16	Vaccines
EP0595970A4 (en)	1995-05-31	Improved vaccine.
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GB9215233D0 (en)	1992-09-02	Vaccines
GB9322702D0 (en)	1993-12-22	Vaccines
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GB9214871D0 (en)	1992-08-26	Vaccines
AU4970193A (en)	1994-03-15	IPNV vaccine
ZA948729B (en)	1995-07-10	Vaccines
ZA939564B (en)	1994-08-15	Vaccines.
ZA957482B (en)	1997-03-06	Vaccine
EP0662782A4 (en)	1995-10-25	Pp14-based therapy.
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EP0603542A3 (en)	1995-11-22	Releasable plug coupling.
ZA924670B (en)	1993-03-31	Ccv vaccine
GB9323820D0 (en)	1994-01-05	Vaccine
ZA933541B (en)	1994-06-21	Vaccines
EP0604923A3 (en)	1994-12-28	Sleeve.
GB9419969D0 (en)	1994-11-16	Vaccine
GR3017505T3 (en)	1995-12-31	N-Alkyl-3-phenyl-3-(2-alkylthiophenoxy)propylamines.
HU275U (en)	1994-04-28	Universal claw-coupling

Legal Events

Date	Code	Title	Description
1995-01-13	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-03-01	17P	Request for examination filed	Effective date: 19941122
1995-03-01	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1996-06-05	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: PFIZER INC.
1997-01-15	A4	Supplementary search report drawn up and despatched	Effective date: 19961126
1997-01-15	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-10-20	17Q	First examination report despatched	Effective date: 19990901
2001-01-12	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2001-02-28	18D	Application deemed to be withdrawn	Effective date: 20000905