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EP0587777A4 - CEA-BINDING PROTEINS AND METHODS OF THEIR INSULATION AND USE. - Google Patents

CEA-BINDING PROTEINS AND METHODS OF THEIR INSULATION AND USE.

Info

Publication number
EP0587777A4
EP0587777A4 EP92913689A EP92913689A EP0587777A4 EP 0587777 A4 EP0587777 A4 EP 0587777A4 EP 92913689 A EP92913689 A EP 92913689A EP 92913689 A EP92913689 A EP 92913689A EP 0587777 A4 EP0587777 A4 EP 0587777A4
Authority
EP
European Patent Office
Prior art keywords
cea
insulation
methods
binding proteins
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92913689A
Other languages
German (de)
French (fr)
Other versions
EP0587777A1 (en
Inventor
Peter Thomas
Carol A Toth
Sibusisiwe M Maswoswe
Joseph V Briggman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Beth Israel Deaconess Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/714,386 external-priority patent/US5278290A/en
Priority claimed from US07/708,885 external-priority patent/US5245017A/en
Priority claimed from US07/708,888 external-priority patent/US5281697A/en
Application filed by Beth Israel Deaconess Medical Center Inc filed Critical Beth Israel Deaconess Medical Center Inc
Publication of EP0587777A1 publication Critical patent/EP0587777A1/en
Publication of EP0587777A4 publication Critical patent/EP0587777A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
EP92913689A 1991-05-31 1992-05-22 CEA-BINDING PROTEINS AND METHODS OF THEIR INSULATION AND USE. Withdrawn EP0587777A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US07/714,386 US5278290A (en) 1991-05-31 1991-05-31 Binding protein for CEA and uses thereof
US07/708,885 US5245017A (en) 1991-05-31 1991-05-31 Method for isolating CEA-binding protein
US708888 1991-05-31
US07/708,888 US5281697A (en) 1991-05-31 1991-05-31 CEA-binding protein and uses thereof
US708885 1991-05-31
US714386 1991-05-31

Publications (2)

Publication Number Publication Date
EP0587777A1 EP0587777A1 (en) 1994-03-23
EP0587777A4 true EP0587777A4 (en) 1995-05-10

Family

ID=27418849

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92913689A Withdrawn EP0587777A4 (en) 1991-05-31 1992-05-22 CEA-BINDING PROTEINS AND METHODS OF THEIR INSULATION AND USE.

Country Status (3)

Country Link
EP (1) EP0587777A4 (en)
AU (1) AU2158292A (en)
WO (1) WO1992021364A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774209B1 (en) * 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
EP1565570A4 (en) 2002-11-12 2005-12-28 Becton Dickinson Co Diagnosis of sepsis or sirs using biomarker profiles
CA2605143A1 (en) 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
US8247370B2 (en) 2006-12-04 2012-08-21 Promedior, Inc. Conjoint therapy for treating fibrotic diseases
WO2009009034A2 (en) * 2007-07-06 2009-01-15 Promedior, Inc Methods and compositions useful in the treatment of mucositis
US8497243B2 (en) 2007-07-06 2013-07-30 Promedior, Inc. Methods and compositions useful in the treatment of mucositis
US9884899B2 (en) 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
DK2405929T3 (en) 2009-03-11 2018-08-27 Promedior Inc SAP polypeptide for use in the treatment of autoimmune disorders and graft-versus-host disease
JP5797565B2 (en) 2009-03-11 2015-10-21 プロメディオール， インコーポレイテッド Treatment and diagnosis method for hypersensitive disorder
UA110323C2 (en) 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
CA2765394C (en) 2009-06-17 2020-08-18 Promedior, Inc. Sap variants and their use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732862A (en) * 1983-11-21 1988-03-22 Alberto Bartorelli Determination of CEA binding substance using anti-goat immunoglobulins
WO1989008255A1 (en) * 1988-03-04 1989-09-08 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516081D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
US4892933A (en) * 1988-04-20 1990-01-09 New England Deaconess Hospital Corporation Monoclonal antibody for colorectal carcinoma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732862A (en) * 1983-11-21 1988-03-22 Alberto Bartorelli Determination of CEA binding substance using anti-goat immunoglobulins
WO1989008255A1 (en) * 1988-03-04 1989-09-08 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BARTORELLI A., BIOMEDICINE AND PHARMACOTHERAPY, vol. 41, no. 1, 1987, pages 2 - 5 *
See also references of WO9221364A1 *
THOMAS P., ET AL., FASEB JOURNAL, vol. 2, no. 4, 1988, BETHESDA, MD US, pages A623 *
TOTH C.A., ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 171, no. 2, 1990, DULUTH, MINNESOTA US, pages 633 - 640 *

Also Published As

Publication number Publication date
WO1992021364A1 (en) 1992-12-10
AU2158292A (en) 1993-01-08
EP0587777A1 (en) 1994-03-23

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19961203