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EP0562943B1 - Zweikammerpackung - Google Patents

Zweikammerpackung Download PDF

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Publication number
EP0562943B1
EP0562943B1 EP19930400738 EP93400738A EP0562943B1 EP 0562943 B1 EP0562943 B1 EP 0562943B1 EP 19930400738 EP19930400738 EP 19930400738 EP 93400738 A EP93400738 A EP 93400738A EP 0562943 B1 EP0562943 B1 EP 0562943B1
Authority
EP
European Patent Office
Prior art keywords
packaging according
capsule
cutting element
punch
packaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19930400738
Other languages
English (en)
French (fr)
Other versions
EP0562943A1 (de
Inventor
Alain Behar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
S O F A B
Silgan Dispensing Systems Le Treport SAS
Original Assignee
S O F A B
Sofab SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S O F A B, Sofab SA filed Critical S O F A B
Publication of EP0562943A1 publication Critical patent/EP0562943A1/de
Application granted granted Critical
Publication of EP0562943B1 publication Critical patent/EP0562943B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0078—Arrangements for separately storing several components

Definitions

  • extemporaneous drugs can be prepared by this route, for example mixing the active component and its vector or liquid support medium.
  • the shutter will be perforated, for example, using the syringe needle to inject the liquid, mix and allow any reactions to take place, then re-aspirate the product.
  • Patent publication FR-A-2 658 487 proposes receptacles with two opposite compartments which are separated by a tearable membrane and showing two external necks of opposite axial openings opposite, one constituting a mouthpiece carrying a pump, the other receiving a push plug carrying a membrane cutting member.
  • the subject of the invention is a device which is both simpler and safer.
  • This device is essentially built around a vial or socket forming a single barrel with two opposite necks, the mouth of one still carrying a pump, but that of the other receiving a capsule with an internal cutting member such as cited above.
  • Pump and capsule sealed on the barrel, the assembly is in the form of a compact cartridge of generally cylindrical appearance containing the two components of the product, capable of being kept upright both in its initial state and after shearing, mixing and successive uses. Its filling phases are independent and simple, its use requires no complicated handling and it easily constitutes a complete aseptic packaging.
  • a tubular segment 1 made of glass, having at its ends two identical rings, respectively 1a and 1b , forms the barrel intended to contain a liquid component and which receives at its upper part a pump 2 of a suitable known model with its pick-up tube 2a , and at its lower part a powder capsule 3 , of also known model, closed by a cover 4 which a punch 5 makes it possible to break by means of its blade 5a , without lose the external seal.
  • the operating button of the lower punch 5 permanently receives a cover 7 capable of serving as a base and carrier if necessary a safety ring 7a , which could be made inviolable.
  • the pump carries a conventional head 8 equipped for example with a spray nozzle 9 which itself serves as a cover in the manner of the base 7 , if necessary wearing like it a safety ring 8 a .
  • the conditioner preferably receives the barrel equipped with the pump and sets up solvent then powder capsule and pellet, the head 8 having advantageously been mounted in advance. The whole operation is done upside down and can be performed under the requisite aseptic conditions.
  • the user just needs to press the rear button of the punch 5 to pierce the seal 4 and release the powder within the solvent by inverting and agitating the device if necessary.
  • the cartridge is then used like a normal bottle fitted with a pump.
  • This device makes it possible, for example, to prepare a solution of a powder component at the time of use and to withdraw this solution by means of a pump, while minimizing the number of manipulations.
  • the device is entirely made of synthetic materials, with the possible exception of the spring of the pump 12 .
  • the latter is assembled and closed by fitting a flange 16a onto the pump body then mounted likewise on the barrel 11 .
  • the dispensing head for example provided with a nasal tip, is here delivered separately; in other cases it could obviously be placed under the cover 18 .
  • the lower opening of the barrel receives the capsule 13 , which has an internal cylindrical well 13a closed by a cover 14 and which the punch 15 closes.
  • the capsule 13 retained by a fitted collar 16b , forms the bottom of the reservoir and its profile laterally spreads the end of the intake tube 12a .
  • the collar 16b carries a tamper-evident cover 17 , the belt of which is retained by breakable bridges 17a along its heel 17b ; here, as we can see, the cover is independent of the punch 15 .
  • This punch which slides in sealed manner in the well 13a , has a blade 15a of an upper edge oblique to the tear line of the cover and which provides a cavity of volume adapted to that of the powder. Its depression (dashed lines) cuts the cover and releases the powder, the bottom of the cavity reaching substantially at that of the reservoir initially formed in the barrel by the capsule; the existence of at least one groove 15b then creates a lower passage which eliminates the dead volumes at the end of use of the product.
  • the punch here carries a rear button which, after detaching the cover 17 , would protrude from the heel of the cartridge to facilitate its initial maneuver, then disappearing so as not to compromise stability in the standing position between two successive uses.
  • the bridges 17a being placed towards the inside of the well 13a , it is possible to break them by driving in, then directly driving the punch 15 , which thus comes clearly back on the heel 17b , because the cover 17 does not fall only later.
  • the tear-off rim of the cover is sufficient in practice to retain the punch after the first use, but it is possible to provide auxiliary stop means in extreme positions 13b such as simple complementary reliefs in profile, however, which can be removed from the mold during manufacture and then interlocked with the mounting.
  • punch 15 and cover 17 are carriers of indented grooves 19 and the stop means 13b comprise a helical ramp; a rotational force on the cover 17 thus causes the punch 15 to rise.
  • the ramp would also be capable of making a bayonet to lock the punch in abutment in its high position on a shoulder such as 13c , thus obtaining a more perfect and safer seal.

Landscapes

  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Package Specialized In Special Use (AREA)

Claims (12)

  1. Verpackung zum Aufbewahren und späteren Vermischen zweier Komponenten und Aufnehmen des so entstandenen Produkts, welche aus einem Zylinder (1) mit zwei äußeren Hälsen besteht, die einander gegenüberliegende axiale Öffnungen formen, wovon eine eine Pumpe (2) tragende Öffnung bildet und die andere eine eine der Komponenten enthaltende Kapsel (3) aufnimmt und ein Zerstörungselement (5) trägt, das mit einem Druckknopf ausgestattet und dicht angebracht ist, wobei der so an beiden Enden verschlossene Zylinder die zweite Komponente aufnimmt.
  2. Verpackung nach Anspruch 1, dadurch gekennzeichnet, daß sie eine Patrone bildet, die in der Lage ist, sowohl in ihrem Originalzustand als auch nach der ersten Anwendung stehend aufbewahrt zu werden.
  3. Verpackung nach Anspruch 1, dadurch gekennzeichnet, daß sie mindestens auf der Kapsel einen Sicherungsring (7a, 8a, 17a) trägt.
  4. Verpackung nach den Ansprüchen 2 und 3, dadurch gekennzeichnet, daß der Sicherungsring unzerstörbar ist.
  5. Verpackung nach Anspruch 2, dadurch gekennzeichnet, daß der Druckknopf des Zerstörungselements dauerhaft eine Kappe (7) trägt, die als Boden dienen kann.
  6. Verpackung nach Anspruch 4, dadurch gekennzeichnet, daß der Druckknopf des Zerstörungselements (15) von einer Kappe (17) bedeckt wird, die entlang einer Bruchlinie auf einem Ansatz (17b) der Patrone festgehalten wird.
  7. Verpackung nach Anspruch 2, dadurch gekennzeichnet, daß das Zerstörungselement einen Stempel (15) bildet, der einen unteren Knopf trägt, der durch Eindrücken hinter einem Ansatz (17b) der Patrone verschwindet.
  8. Verpackung nach den Ansprüchen 4 und 5, dadurch gekennzeichnet, daß die Kappe (17) des Zerstörungselements , von diesem unabhängig ist und nach ihrem Eindrücken entfernt wird.
  9. Verpackung nach Anspruch 1, dadurch gekennzeichnet, daß die Pumpe mit einem Ansaugschlauch (12a) versehen ist, während die Kapsel den Behälterboden bildet und das Profil dieser Kapsel seitlich vom Ende des Schlauchs abweicht.
  10. Verpackung nach Anspruch 1, dadurch gekennzeichnet, daß das Zerstörungselement einen Stempel (15) mit Schneide bildet, der einen Hohlraum einschließt, dessen Boden sich nach Betätigung etwa in Höhe des ursprünglich im Zylinder von der Kapsel gebildeten befindet, wobei durch einen unteren Durchgang (15b) am Schluß der Anwendung des Produkts keine Totvolumina entstehen.
  11. Verpackung nach Anspruch 10, dadurch gekennzeichnet, daß Mittel (13b) zum Halten in den äußersten Positionen den in oberer Position im Anschlag befindlichen Stempel verriegeln.
  12. Verpackung nach einem der Ansprüche 1 bis 11, dadurch gekennzeichnet, daß sie vollständig durch Steckverbindungen zusammengebaut ist.
EP19930400738 1992-03-23 1993-03-22 Zweikammerpackung Expired - Lifetime EP0562943B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9203436A FR2688759B1 (fr) 1992-03-23 1992-03-23 Conditionnement double.
FR9203436 1992-03-23

Publications (2)

Publication Number Publication Date
EP0562943A1 EP0562943A1 (de) 1993-09-29
EP0562943B1 true EP0562943B1 (de) 1996-09-25

Family

ID=9427938

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19930400738 Expired - Lifetime EP0562943B1 (de) 1992-03-23 1993-03-22 Zweikammerpackung

Country Status (3)

Country Link
EP (1) EP0562943B1 (de)
DE (1) DE69304968T2 (de)
FR (1) FR2688759B1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0821975A1 (de) * 1996-07-31 1998-02-04 Novartis AG (Novartis SA) (Novartis Inc.) Dosiervorrichtung für fliessfähige Stoffe
DE19749514A1 (de) * 1997-11-08 1999-05-12 Pfeiffer Erich Gmbh & Co Kg Verfahren zum Ausbringen von wenigstens zwei verschiedenen Medien und Spender dafür
US6745763B2 (en) * 1998-10-27 2004-06-08 Garth T. Webb Vaporizing device for administering sterile medication
US6382204B1 (en) 1999-10-14 2002-05-07 Becton Dickinson And Company Drug delivery system including holder and drug container
CN106395078A (zh) * 2016-10-17 2017-02-15 无锡市日升化工有限公司 一种具有高效率防沉降功能的液体储存桶

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3760986A (en) * 1970-08-19 1973-09-25 Schuyler Dev Corp Dispensing bottles with pump means for simultaneous dispensing
GB2220930A (en) * 1988-06-07 1990-01-24 Fisons Plc Introducing additive into a container
FR2658487B1 (fr) * 1990-02-21 1993-12-24 Valois Dispositif pour nebuliser un medicament constitue d'un melange a former au moment de l'emission.

Also Published As

Publication number Publication date
DE69304968T2 (de) 1997-03-27
FR2688759A1 (fr) 1993-09-24
EP0562943A1 (de) 1993-09-29
DE69304968D1 (de) 1996-10-31
FR2688759B1 (fr) 1994-06-10

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