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EP0413721A4 - Human gm-csf variants - Google Patents

Human gm-csf variants

Info

Publication number
EP0413721A4
EP0413721A4 EP19890905045 EP89905045A EP0413721A4 EP 0413721 A4 EP0413721 A4 EP 0413721A4 EP 19890905045 EP19890905045 EP 19890905045 EP 89905045 A EP89905045 A EP 89905045A EP 0413721 A4 EP0413721 A4 EP 0413721A4
Authority
EP
European Patent Office
Prior art keywords
human
csf variants
csf
variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890905045
Other versions
EP0413721A1 (en
Inventor
Mathew Alexander Vadas
Angel Francisco Lopez
Mary Frances Shannon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medvet Science Pty Ltd
Original Assignee
Medvet Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medvet Science Pty Ltd filed Critical Medvet Science Pty Ltd
Publication of EP0413721A1 publication Critical patent/EP0413721A1/en
Publication of EP0413721A4 publication Critical patent/EP0413721A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19890905045 1988-04-21 1989-04-21 Human gm-csf variants Withdrawn EP0413721A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPI784888 1988-04-21
AU7848/88 1988-04-21
AUPI994388 1988-08-19
AU9943/88 1988-08-19

Publications (2)

Publication Number Publication Date
EP0413721A1 EP0413721A1 (en) 1991-02-27
EP0413721A4 true EP0413721A4 (en) 1991-11-13

Family

ID=25643468

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890905045 Withdrawn EP0413721A4 (en) 1988-04-21 1989-04-21 Human gm-csf variants

Country Status (4)

Country Link
EP (1) EP0413721A4 (en)
JP (1) JPH03503897A (en)
AU (1) AU615550B2 (en)
WO (1) WO1989010403A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2060699A1 (en) * 1991-02-11 1992-08-12 Isia Bursuker Gm-csf inhibiting oligopeptides
SG52238A1 (en) * 1993-07-28 1998-09-28 Medvet Science Pty Ltd Haemopoietic growth factor antagonists
US6465616B1 (en) 1994-04-08 2002-10-15 Bresagen Limited Interleukin-5 antagonist
AUPN378095A0 (en) * 1995-06-23 1995-07-20 Bresagen Limited Haemopoietic growth factor antagonists and uses therefor
AU703052B2 (en) * 1995-06-23 1999-03-11 Bresagen Limited Haemopoietic growth factor antagonists and uses therefor
US11267859B2 (en) 2017-06-09 2022-03-08 The Regents Of The University Of Colorado, A Body Corporate GM-CSF mimetics and methods of making and using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
ZA858833B (en) * 1984-11-20 1986-06-25 Schering Biotech Corp Cdna clones coding for polypeptides exhibiting human granulocyte macrophage and eosinophil cellular growth factor activity
US5391485A (en) * 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
AU606585B2 (en) * 1985-10-03 1991-02-14 Biogen, Inc. Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells
DE3545568A1 (en) * 1985-12-21 1987-07-16 Hoechst Ag GM-CSF-PROTEIN, ITS DERIVATIVES, PRODUCTION OF SUCH PROTEINS AND THEIR USE
JPH01502196A (en) * 1987-02-06 1989-08-03 ジェネテイックス・インスティテュート・インコーポレイテッド Colony stimulating factor with reduced carbohydrate content
EP0299746B1 (en) * 1987-07-16 1992-08-26 Schering Corporation Purification of gm-csf
AU626530B2 (en) * 1987-07-17 1992-08-06 Schering Biotech Corporation Human granulocyte-macrophage colony stimulating factor and muteins thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Journal of Immunology, Vol. 141, No. 3, August 1, 1988, USA, pages 881-889; IAN CLARK-LEWIS et al.: "Structure-functions studies of human granulocyte-macrophage colony stimulating factor", Abstract; figures 2,5,6; table II. *
Lymphokine Research, Vol. 6, No. 1, 1987, New York, USA, A.F. LOPEZ et al.: "Biological properties of recombinant and chemically-synthesized human granulocyte-macrophage colony-stimulating-factor(GM-CSF)", Abstract No. 1322. *
See also references of WO8910403A1 *

Also Published As

Publication number Publication date
JPH03503897A (en) 1991-08-29
EP0413721A1 (en) 1991-02-27
WO1989010403A1 (en) 1989-11-02
AU615550B2 (en) 1991-10-03
AU3549489A (en) 1989-11-24

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19901017

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19910924

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STAA Information on the status of an ep patent application or granted ep patent

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18W Application withdrawn

Withdrawal date: 19920610