EP0386002A4 - Gene transfer for drug resistance - Google Patents

Gene transfer for drug resistance

Info

Publication number: EP0386002A4
Authority: EP; European Patent Office
Prior art keywords: gene transfer; drug resistance; drug; resistance; gene
Prior art date: 1987-05-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19880906678

Other versions

EP0386002A1 (en

Inventor

Stephen Barnard Howell

Inder Verma

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Research Development Foundation

Original Assignee

Clayton Foundation for Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-28

Filing date

1988-05-26

Publication date

1990-09-26

1988-05-26 Application filed by Clayton Foundation for Research filed Critical Clayton Foundation for Research

1990-09-12 Publication of EP0386002A1 publication Critical patent/EP0386002A1/en

1990-09-26 Publication of EP0386002A4 publication Critical patent/EP0386002A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Immunology (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

EP19880906678 1987-05-28 1988-05-26 Gene transfer for drug resistance Withdrawn EP0386002A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878712528A GB8712528D0 (en)	1987-05-28	1987-05-28	Gene transfer
GB8712528		1987-05-28

Publications (2)

Publication Number	Publication Date
EP0386002A1 EP0386002A1 (en)	1990-09-12
EP0386002A4 true EP0386002A4 (en)	1990-09-26

Family

ID=10618026

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP19880906678 Withdrawn EP0386002A4 (en)	1987-05-28	1988-05-26	Gene transfer for drug resistance
EP19880304759 Pending EP0293193A3 (en)	1987-05-28	1988-05-26	Gene transfer for drug resistance

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
EP19880304759 Pending EP0293193A3 (en)	1987-05-28	1988-05-26	Gene transfer for drug resistance

Country Status (11)

Country	Link
EP (2)	EP0386002A4 (en)
JP (1)	JPH02503512A (en)
AU (1)	AU618749B2 (en)
DK (1)	DK34489A (en)
FI (1)	FI894851A0 (en)
GB (1)	GB8712528D0 (en)
IL (1)	IL86532A0 (en)
NZ (1)	NZ224802A (en)
PT (1)	PT87597B (en)
WO (1)	WO1988009383A1 (en)
ZA (1)	ZA883804B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8919607D0 (en) *	1989-08-30	1989-10-11	Wellcome Found	Novel entities for cancer therapy
US6337209B1 (en)	1992-02-26	2002-01-08	Glaxo Wellcome Inc.	Molecular constructs containing a carcinoembryonic antigen regulatory sequence
US6770274B1 (en) *	1990-09-14	2004-08-03	The General Hospital Corporation	Viral mutant HSV mediated destruction of neoplastic cells
CA2051289C (en) *	1990-09-14	2002-11-26	Robert L. Martuza	Viral mediated destruction of neoplastic cells
US6555370B1 (en)	1990-11-13	2003-04-29	Immunex Corporation	Bifunctional selectable fusion genes
AU650085B2 (en) *	1990-11-13	1994-06-09	Immunex Corporation	Bifunctional selectable fusion genes
DE4444949C1 (en) *	1994-12-16	1996-11-21	Deutsches Krebsforsch	Vectors and viruses for gene therapy
US9023031B2 (en)	1997-08-13	2015-05-05	Verathon Inc.	Noninvasive devices, methods, and systems for modifying tissues
US7306591B2 (en)	2000-10-02	2007-12-11	Novasys Medical, Inc.	Apparatus and methods for treating female urinary incontinence

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986000922A1 (en) *	1984-07-30	1986-02-13	The Salk Institute For Biological Studies	Retroviral gene transfer vectors

1987
- 1987-05-28 GB GB878712528A patent/GB8712528D0/en active Pending
1988
- 1988-05-26 NZ NZ224802A patent/NZ224802A/en unknown
- 1988-05-26 EP EP19880906678 patent/EP0386002A4/en not_active Withdrawn
- 1988-05-26 AU AU21253/88A patent/AU618749B2/en not_active Ceased
- 1988-05-26 EP EP19880304759 patent/EP0293193A3/en active Pending
- 1988-05-26 JP JP88506309A patent/JPH02503512A/en active Pending
- 1988-05-26 WO PCT/US1988/001817 patent/WO1988009383A1/en not_active Application Discontinuation
- 1988-05-27 ZA ZA883804A patent/ZA883804B/en unknown
- 1988-05-27 PT PT87597A patent/PT87597B/en not_active IP Right Cessation
- 1988-05-27 IL IL86532A patent/IL86532A0/en unknown
1989
- 1989-01-26 DK DK034489A patent/DK34489A/en not_active Application Discontinuation
- 1989-10-13 FI FI894851A patent/FI894851A0/en not_active IP Right Cessation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986000922A1 (en) *	1984-07-30	1986-02-13	The Salk Institute For Biological Studies	Retroviral gene transfer vectors

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, vol. 83, 1987, abstract no. 85881, Biological Abstracts, Inc., Philadelphia, PA, US; S.M.W. CHANG et al.: "Construction of a defective retrovirus containing the human hypoxanthine phosphoribosyltransferase complementary DNA and its expression in cultured cells and mouse bone marrow", & MOL. CELL. BIOL. 7(2): 854-863, 1987 *
BIOTECHNOLOGY, vol. 3, no. 3, August 1985, pages 689-693, New York, US; D. McCORMICK: "Human gene therapy: The first round" *
MOL. BIOL. MED., vol. 4, 1987, pages 157-168, Academic Press, Inc., London, GB; S.B. HOWELL et al.: "Gene therapy for thioguanine-resistant human leukemia" *
MOLECULAR AND CELLULAR BIOLOGY, vol. 7, no. 5, May 1987, pages 1797-1806, American Society for microbiology; R.A. BOSSELMAN et al.: "Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: Expression of moloney murine leukemia virus structural genes via the metallothionein promoter" *
See also references of WO8809383A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 259, no. 12, 25th June 1984, pages 7842-7849, the American Society of Biological Chemists, Inc., US; R.C. WILLIS et al.: "Partial phenotypic correction of human lesch-nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector" *

Also Published As

Publication number	Publication date
ZA883804B (en)	1990-08-29
EP0293193A3 (en)	1990-09-12
NZ224802A (en)	1991-01-29
PT87597B (en)	1992-09-30
FI894851A0 (en)	1989-10-13
IL86532A0 (en)	1988-11-15
DK34489D0 (en)	1989-01-26
GB8712528D0 (en)	1987-07-01
JPH02503512A (en)	1990-10-25
EP0386002A1 (en)	1990-09-12
PT87597A (en)	1988-06-01
EP0293193A2 (en)	1988-11-30
AU2125388A (en)	1988-12-21
AU618749B2 (en)	1992-01-09
DK34489A (en)	1989-01-26
WO1988009383A1 (en)	1988-12-01

Publication	Publication Date	Title
AU101237S (en)	1988-09-08	Transfer cannula
CS403391A3 (en)	1992-08-12	Pharmaceutical
EP0313363A3 (en)	1989-10-11	Transfer device
IL86378A0 (en)	1988-11-15	Phosphinothricin-resistant gene
GB8828289D0 (en)	1989-01-05	Patient transfer arrangement
GB2202340B (en)	1990-05-23	Heat-sensitive transfer material
JPS6479146A (en)	1989-03-24	Drug composition
ZA883804B (en)	1990-08-29	Gene transfer for drug resistance
GB8820127D0 (en)	1988-09-28	Heat-sensitive transfer material
GB8725177D0 (en)	1987-12-02	Transfer seat
IE881614L (en)	1988-11-28	Gene transfer for drug resistance
GB2215233B (en)	1992-01-08	Mass transfer trays
GB8727015D0 (en)	1987-12-23	Patient transfer device
GB2212415B (en)	1991-12-18	Mass transfer trays
GB8726581D0 (en)	1987-12-16	Dna sequence
ZA884700B (en)	1989-03-29	Nucleic acid derivatives
JPS6430589A (en)	1989-02-01	Phosphinoslicin resistant gene
GB8802786D0 (en)	1988-03-09	Fluid transfer means
EP0306946A3 (en)	1990-06-13	Pressure-sensitive transfer member
GB8704055D0 (en)	1987-03-25	Patient transfer system
GB8717908D0 (en)	1987-09-03	Data transfer
GB8706595D0 (en)	1987-04-23	Rapid information transfer
RO101663B1 (en)	1992-05-07	Anti-hemorroidal medication
GB8719414D0 (en)	1987-09-23	Dna sequence
EG18297A (en)	1992-10-30	New drug preparation

Legal Events

Date	Code	Title	Description
1990-07-28	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1990-09-12	17P	Request for examination filed	Effective date: 19891021
1990-09-12	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1990-09-26	A4	Supplementary search report drawn up and despatched	Effective date: 19900809
1990-09-26	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1990-11-07	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: RESEARCH DEVELOPMENT FOUNDATION
1991-11-06	XX	Miscellaneous (additional remarks)	Free format text: VERBUNDEN MIT 88304759.9/0293193 (EUROPAEISCHE ANMELDENUMMER/VEROEFFENTLICHUNGSNUMMER) DURCH ENTSCHEIDUNG VOM 23.09.91.
1992-02-26	17Q	First examination report despatched	Effective date: 19920114
1992-12-09	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1993-01-27	18D	Application deemed to be withdrawn	Effective date: 19920725