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EP0348762B1 - Closure for pharmaceutical bottles - Google Patents

Closure for pharmaceutical bottles Download PDF

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Publication number
EP0348762B1
EP0348762B1 EP89111031A EP89111031A EP0348762B1 EP 0348762 B1 EP0348762 B1 EP 0348762B1 EP 89111031 A EP89111031 A EP 89111031A EP 89111031 A EP89111031 A EP 89111031A EP 0348762 B1 EP0348762 B1 EP 0348762B1
Authority
EP
European Patent Office
Prior art keywords
closure
tear
stopper
disc
bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP89111031A
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German (de)
French (fr)
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EP0348762A1 (en
Inventor
Dieter Duschek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wez Kunststoffwerk AG
Original Assignee
Wez Kunststoffwerk AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wez Kunststoffwerk AG filed Critical Wez Kunststoffwerk AG
Priority to AT89111031T priority Critical patent/ATE78779T1/en
Publication of EP0348762A1 publication Critical patent/EP0348762A1/en
Application granted granted Critical
Publication of EP0348762B1 publication Critical patent/EP0348762B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the present invention relates to a closure arrangement for pharmaceutical bottles with a stopper which can be pierced to remove medication from the bottle by means of a hollow needle and which closes the bottle mouth and with a rolled rim ring formed on the bottle around the bottle mouth and the stopper, over the stopper one by one Line of weakness limited closure cap having a tear-off disc that can be removed when the closure is opened.
  • a closure arrangement of the type mentioned is known.
  • This closure arrangement consists of the combination of a cap which is attached to the bottle and a rubber stopper which seals the pharmaceutical bottle.
  • the cap has an upper-side component with an inner and an outer part.
  • the inner and outer parts are connected to each other by breakable bridge parts.
  • the inner part is connected to a lid part which can be pressed away from the bottle by means of thumb pressure in order to break the bridge parts and to detach and remove the inner part of the cap from the outer part.
  • the rubber stopper for inserting a hollow needle is then released under the inner part of the cap.
  • a disadvantage of this closure arrangement is that the lid part has to be removed from the bottle with the thumb, with the fingernail growth site being uncomfortably stressed.
  • the object of the present invention is to provide a closure arrangement of the type mentioned at the outset which is economically advantageous and in which the tear-off disk can be removed safely, conveniently and quickly with one hand.
  • the closure cap is formed in one piece with the tear-off disk made of plastic, that the closure cap is fastened by pressure from the top to the bottom in the axial direction of the bottle when the closure is unopened, so that the pressure on it the sealing cap tears the connection between the sealing cap and the tear-off disc and the tear-off disc can be removed and that there is a spacer between the tear-off disc which is held by the weakening line when the closure is unopened and the stopper underneath, which does not exceed the outline of the tear-off disc.
  • This closure arrangement is economically advantageous because the closure cap and the tear-off disk are produced in one process step, economically advantageously from plastic.
  • the cap can be pressed safely and comfortably with one hand in the direction of the bottle when the cap is not opened.
  • the tear-off disk separates from the closure cap and releases the stopper for the removal of medication in the bottle through a hollow needle that can be pierced through the stopper. There is no risk of injury with this cap.
  • the spacer can advantageously be formed in one piece with the tear-off disk or with the stopper. This measure enables the closure arrangement to consist of only two economically advantageous parts, namely the closure cap and the stopper.
  • the spacer can be formed in one piece with the tear-off washer and the end of the tear-off washer facing the stopper be in tight contact with the stopper when the closure is not opened. This measure ensures that the surface of the stopper intended for the removal of a medicament lying in the bottle remains protected from contamination before the tear-off disk is removed.
  • the spacer can also be formed in one piece with the stopper, and the end of the stopper facing the tear-off disk, when the closure is unopened, bears tightly against the tear-off disk.
  • the closure cap advantageously widens in a funnel shape from the line of weakness in the direction facing away from the bottle.
  • the handling of the sealing cap becomes easier because when pressing the sealing cap the tear-off disc separating from the sealing cap does not prevent pressing.
  • the tear-off disc remains set back in the funnel-shaped part of the sealing cap.
  • the closure cap may have on the inside of its outer jacket region, which extends over the rolled rim ring, an annular latching bead which engages behind the edge of the rolled rim ring facing away from the bottle mouth when the closure is not opened.
  • the snap bead simply holds the unopened cap on the bottle and enables the cap to be easily attached to the bottle.
  • the closure cap can also have a second, annular bead on the inside of its outer jacket region, which extends over the rolled rim ring. This second bead holds the pressed-in, opened closure cap in this position.
  • the spacer can be formed in one piece with the tear-off disc, the end of the tear-off disc facing the stopper being tight on the stopper when the closure is unopened is present and the distance between the latching bead and the second bead corresponds to the smallest distance between the parts of the closure cap surrounding the tear-off disk and the stopper when the closure is unopened.
  • the spacer can also be formed in one piece with the stopper, the end of the stopper facing the tear-off disc when the closure is unopened Tear-off disc is tight and the distance between the snap-in bead and the second bead corresponds to the smallest distance between the parts of the closure cap surrounding the tear-off disc and the stopper when the closure is unopened.
  • the distance between the latching bead and the second bead can correspond to the width of the rolled edge ring. At this distance between the two beads, the closure cap sits more securely on the bottle when the closure is not opened.
  • FIG. 1 shows a closure arrangement for a pharmaceutical bottle 1, which can be an injection bottle or a transfusion bottle, for example.
  • the bottle 1 is closed by a rubber plug 2 inserted into the bottle mouth.
  • the stopper can be pierced by means of a hollow needle and the medication located in the bottle 1 can be removed from the bottle 1 through the hollow needle.
  • the plug 2 is enveloped and protected on the outside by a sealing cap 3.
  • the closure cap 3 also surrounds a rolled rim ring 4 formed on the bottle 1 around the bottle mouth.
  • the closure cap 3 and the tear-off disc 5 are made of plastic, of polypropylene.
  • the closure cap 3 is fastened so that it can be displaced by pressure on the rolled rim ring 4 in the direction of the bottle 1.
  • the end facing the stopper 2 of the tear-off disk 5, which can be separated by pressure from the closure cap 3 bears tightly against the stopper 2. This measure prevents contamination of the part of the stopper 2 to be pierced before the closure is opened.
  • the annular latching bead 7 holds the cap 3 on the bottle 1 behind the edge of the rolled rim ring 4 facing away from the bottle mouth.
  • the spacer is formed in one piece with the tear-off disk 5 in the arrangement according to FIG.
  • FIGS. 3 and 4 A further closure arrangement with the bottle 1 is shown in FIGS. 3 and 4.
  • a pierceable, rubber stopper 8 also closes the bottle 1.
  • a closure cap 9 surrounds the rolled rim ring 4 and the stopper 8 formed around the bottle mouth.
  • the closure cap 9 is attached by the snap bead 7 which engages behind the rolled rim ring 4 the bottle 1 held.
  • the spacer lying between the tearing disk 10 and the plug 8 when the closure is unopened is formed in one piece with the plug 8.
  • the extension of the stopper 8 serving as a spacer is in close contact with the tear-off disk 10 in FIG. 3 and prevents any contamination of the part of the stopper 8 intended for piercing.
  • the tear-off disk 10 and the closure cap 9 are made in one piece from plastic. According to FIG. 3, the tear-off disk 10 covering the stopper 8 when the closure is unopened is held on the closure cap 9 via the line of weakness 11.
  • the closure caps 3 and 9 shown in FIGS. 1 to 4 expand in a funnel shape from the weakening lines 6 and 11 in the direction facing away from the bottle 1.
  • the sealing caps 3 and 9 have a second, annular bead 12 on the inside of their outer jacket region, which extends over the rolled rim ring 4.
  • the distance between the latching bead 7 and the second bead 12 corresponds in all figures to the smallest distance between the parts of the sealing cap 3 or 9 surrounding the tear-off disk 5 or 10 and the stopper 2 or 8 in the case of an unopened closure according to FIG. 1 or 3 the distance between the latching bead 7 and the second bead 12 the width of the rolled rim ring 4.
  • the closure caps 3, 9 are supported not only on the stopper 2, 8 but also over the second bead 12 on the bottle in the direction of the bottle 1 edge of the rolled rim ring 4 facing the bottle mouth.
  • the bottle 1 After removal of the tear-off disk 5 with one hand, the bottle 1 is available for removing a medicament lying in the bottle 1 by means of a hollow needle.
  • the cap 3 holds the stopper 2 in the bottle mouth because, after the cap 3 is pressed in, the second bead 12 on the one hand engages behind the edge of the rolled rim ring 4 facing away from the bottle mouth and engages there, and on the other hand the parts of the cap 3 surrounding the tear-off disc 5 Line stopper 2.
  • the opening process of the bottle 1 shown in FIG. 3, provided with a closure proceeds in a similar manner. Press in the direction indicated by the arrows 14 in FIG. 4 on the closure cap 9 until the tear-off disk 10 separates from the closure cap 9 at the line of weakness 11.
  • the extension of the plug 8 serving as a spacer then projects through the opening that has become free in the sealing cap 9.
  • the stopper 8 can subsequently be pierced with a hollow needle and the medication lying in the bottle 1 can be removed.
  • the stopper 8 is held in the bottle mouth by the parts of the closure cap 9 which are in contact with it, because the closure cap is in turn held on the bottle 1 by the second bead 12 which is locked behind the rolled rim ring 4.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)

Description

Die vorliegende Erfindung betrifft eine Verschlussanordnung für pharmazeutische Flaschen mit einem zur Entnahme von Medikamenten aus der Flasche mittels einer Hohlnadel durchstechbaren, die Flaschenmündung verschliessenden Stopfen und mit einer einen an der Flasche um die Flaschenmündung angeformten Rollrandring und den Stopfen umhüllenden, über dem Stopfen eine durch eine Schwächungslinie begrenzte, bei der Oeffnung des Verschlusses entfernbare Abrisscheibe aufweisenden Verschlusskappe.The present invention relates to a closure arrangement for pharmaceutical bottles with a stopper which can be pierced to remove medication from the bottle by means of a hollow needle and which closes the bottle mouth and with a rolled rim ring formed on the bottle around the bottle mouth and the stopper, over the stopper one by one Line of weakness limited closure cap having a tear-off disc that can be removed when the closure is opened.

Aus der DE-PS 1.207.043 ist eine Verschlussanordnung der eingangs erwähnten Art bekannt. Diese Verschlussanordnung besteht aus der Kombination aus einer Kappe, die auf der Flasche befestigt ist und aus einem die pharmazeutische Flasche durchstechbar verschliessenden Gummistopfen. Die Kappe weist einen oberseitigen Bauteil mit einem inneren und mit einem äusseren Teil auf. Die inneren und äusseren Teile sind durch zerbrechbare Brückenteile miteinander verbunden. Der innere Teil ist mit einem Deckelteil vebunden, der vermittels Daumendruck von der Flasche weggedrückt werden kann, um dabei die Brückenteile zu zerbrechen und den inneren Teil der Kappe von dem äusseren Teil zu lösen und zu entfernen. Unter dem inneren Teil der Kappe wird danach der Gummistopfen für das Einstechen einer Hohlnadel frei. Ein Nachteil dieser Verschlussanordnung besteht darin, dass der Deckelteil von der Flasche mit dem Daumen entfernt werden muss, wobei die Fingernagelanwuchsstelle unangenehm beansprucht wird. An den aus Metall bestehenden Bruchstellen der Brückenteile besteht ausserdem Verletzungsgefahr. Ein weiterer Nachteil wirtschaftlicher Natur ist dadurch gegeben, dass für die Verschlussanordnung zu viele Teile verwendet werden müssen, nämlich ein auf die Flasche aufbördelbarer Teil, ein damit verbundener Deckelteil und ein Gummistopfen. Für die Aufbördelung der Kappe auf die Flasche und für die Verbindung des inneren Teiles mit dem Deckelteil benötigt man aufwendige Spezialeinrichtungen. Die Herstellungskosten der aus Metall bestehenden Kappenteile sind auch verhältnismässig hoch.From DE-PS 1.207.043 a closure arrangement of the type mentioned is known. This closure arrangement consists of the combination of a cap which is attached to the bottle and a rubber stopper which seals the pharmaceutical bottle. The cap has an upper-side component with an inner and an outer part. The inner and outer parts are connected to each other by breakable bridge parts. The inner part is connected to a lid part which can be pressed away from the bottle by means of thumb pressure in order to break the bridge parts and to detach and remove the inner part of the cap from the outer part. The rubber stopper for inserting a hollow needle is then released under the inner part of the cap. A disadvantage of this closure arrangement is that the lid part has to be removed from the bottle with the thumb, with the fingernail growth site being uncomfortably stressed. There is also a risk of injury at the metal break points of the bridge parts. Another disadvantage of an economic nature is that too many parts have to be used for the closure arrangement, namely a part that can be flanged onto the bottle, a lid part connected to it and a rubber stopper. For the flanging of the cap onto the bottle and for the connection of the inner part with the lid part, complex special equipment is required. The manufacturing costs of the cap parts made of metal are also relatively high.

Aufgabe der vorliegenden Erfindung ist es, eine Verschlussanordnung der eingangs erwähnten Art zu schaffen, die wirtschaftlich vorteilhaft ist und bei welcher die Abrisscheibe mit einer Hand ungefährlich, bequem und schnell entfernt werden kann.The object of the present invention is to provide a closure arrangement of the type mentioned at the outset which is economically advantageous and in which the tear-off disk can be removed safely, conveniently and quickly with one hand.

Die gestellte Aufgabe ist dadurch gelöst, dass die Verschlusskappe mit der Abrisscheibe aus Kunststoff einstückig ausgebildet ist, dass die Verschlusskappe bei ungeöffnetem Verschluss am Rollrandring der Flasche in axialer Richtung der Flasche von oben nach unten durch Druck verschiebbar befestigt ist, so dass durch den Druck auf die verschlusskappe die Verbindung zwischen der verschlusskappe und der Abrisscheibe reisst und die Abrisscheibe entfernt werden kann und dass zwischen der an der Verschlusskappe bei ungeöffnetem Verschluss über die Schwächungslinie festgehaltene Abrisscheibe und dem darunter liegenden Stopfen ein die Umrisslinie der Abrisscheibe nicht überschreitendes Distanzstück vorhanden ist. Diese Verschlussanordnung ist wirtschaftlich vorteilhaft, denn die Verschlusskappe wird mit der Abrisscheibe in einem Verfahrensschritt, wirtschaftlich vorteilhaft aus Kunststoff hergestellt. Die Verschlusskappe kann bei ungeöffnetem Verschluss auf der Flasche in Richtung der Flasche ungefährlich und bequem mit einer Hand gedrückt werden. Die Abrisscheibe trennt sich dabei von der Verschlusskappe und gibt den Stopfen für die Entnahme eines in der Flasche befindlichen Medikamentes durch eine durch den Stopfen durchstechbare Hohlnadel frei. Eine Verletzungsgefahr besteht bei dieser Verschlusskappe nicht.The object is achieved in that the closure cap is formed in one piece with the tear-off disk made of plastic, that the closure cap is fastened by pressure from the top to the bottom in the axial direction of the bottle when the closure is unopened, so that the pressure on it the sealing cap tears the connection between the sealing cap and the tear-off disc and the tear-off disc can be removed and that there is a spacer between the tear-off disc which is held by the weakening line when the closure is unopened and the stopper underneath, which does not exceed the outline of the tear-off disc. This closure arrangement is economically advantageous because the closure cap and the tear-off disk are produced in one process step, economically advantageously from plastic. The cap can be pressed safely and comfortably with one hand in the direction of the bottle when the cap is not opened. The tear-off disk separates from the closure cap and releases the stopper for the removal of medication in the bottle through a hollow needle that can be pierced through the stopper. There is no risk of injury with this cap.

Das Distanzstück kann vorteilhafterweise mit der Abrisscheibe oder mit dem Stopfen einstückig ausgebildet sein. Diese Massnahme ermöglicht, dass die Verschlussanordnung nur aus zwei wirtschaftlich vorteilhaften Teilen besteht, nämlich aus der Verschlusskappe und aus dem Stopfen.The spacer can advantageously be formed in one piece with the tear-off disk or with the stopper. This measure enables the closure arrangement to consist of only two economically advantageous parts, namely the closure cap and the stopper.

Das Distanzstück kann mit der Abrisscheibe einstückig ausgebildet sein und dabei das dem Stopfen zugekehrte Ende der Abrisscheibe bei ungeöffnetem Verschluss am Stopfen dicht anstehen. Diese Massnahme sichert, dass die für die Entnahme eines in der Flasche liegenden Medikamentes vorgesehene Oberfläche des Stopfens vor Entfernung der Abrisscheibe vor Verunreinigungen geschützt bleibt.The spacer can be formed in one piece with the tear-off washer and the end of the tear-off washer facing the stopper be in tight contact with the stopper when the closure is not opened. This measure ensures that the surface of the stopper intended for the removal of a medicament lying in the bottle remains protected from contamination before the tear-off disk is removed.

Das Distanzstück kann aber auch mit dem Stopfen einstückig ausgebildet sein und dabei das der Abrisscheibe zugekehrte Ende des Stopfens bei ungeöffnetem Verschluss an der Abrisscheibe dicht anstehten. Bei dieser Anordnung wird das Eindringen von Verunreinigungen zur für die Entnahme des in der Flasche liegenden Medikamentes mittels Hohlnadel vorgesehenen Oberfläche des Stopfens vor Entfernung der Abrisscheibe verhindert.However, the spacer can also be formed in one piece with the stopper, and the end of the stopper facing the tear-off disk, when the closure is unopened, bears tightly against the tear-off disk. With this arrangement, the penetration of contaminants to the surface of the stopper provided for the removal of the medication lying in the bottle by means of a hollow needle is prevented before the tear-off disk is removed.

Vorteilhafterweise erweitert sich die Verschlusskappe in der der Flasche abgekehrten Richtung von der Schwächungslinie aus trichterförmig. Die Handhabung der Verschlusskappe wird dadurch einfacher, weil beim Drücken auf die Verschlusskappe die sich von der Verschlusskappe trennende Abrisscheibe das Drücken nicht hindert. Die Abrisscheibe bleibt im trichterförmigen Teil der Verschlusskappe zurückversetzt.The closure cap advantageously widens in a funnel shape from the line of weakness in the direction facing away from the bottle. The handling of the sealing cap becomes easier because when pressing the sealing cap the tear-off disc separating from the sealing cap does not prevent pressing. The tear-off disc remains set back in the funnel-shaped part of the sealing cap.

Die Verschlusskappe kann an der Innenseite ihres äusseren, über den Rollrandring reichenden Mantelbereiches einen bei ungeöffnetem Verschluss hinter der der Flaschenmündung abgekehrten Kante des Rollrandringes greifenden, ringförmigen Einrastwulst aufweisen. Der Einrastwulst hält so die ungeöffnete Verschlusskappe einfacherweise an der Flasche und ermöglicht ein einfaches Anbringen der Verschlusskappe auf die Flasche.The closure cap may have on the inside of its outer jacket region, which extends over the rolled rim ring, an annular latching bead which engages behind the edge of the rolled rim ring facing away from the bottle mouth when the closure is not opened. The snap bead simply holds the unopened cap on the bottle and enables the cap to be easily attached to the bottle.

Die Verschlusskappe kann an der Innenseite ihres äusseren, über den Rollrandring reichenden Mantelbereiches auch einen zweiten, ringförmigen Wulst aufweisen. Dieser zweite Wulst hält die eingedrückte, geöffnete Verschlusskappe in dieser Stellung.The closure cap can also have a second, annular bead on the inside of its outer jacket region, which extends over the rolled rim ring. This second bead holds the pressed-in, opened closure cap in this position.

Um den Stopfen sowohl bei ungeöffnetem als auch bei geöffnetem Verschluss durch die die Abrisscheibe umgebenden Teile der Verschlusskappe in der Flaschenmündung halten zu können, kann das Distanzstück mit der Abrisscheibe einstückig ausgebildet sein, wobei das dem Stopfen zugekehrte Ende der Abrisscheibe bei ungeöffnetem Verschluss am Stopfen dicht ansteht und der Abstand zwischen dem Einrastwulst und dem zweiten Wulst der kleinsten Distanz zwischen den die Abrisscheibe umgebenden Teilen der Verschlusskappe und dem Stopfen bei ungeöffnetem Verschluss entspricht.In order to be able to hold the stopper in the bottle mouth both when the closure is open and when it is open by the parts of the closure cap surrounding the tear-off disc, the spacer can be formed in one piece with the tear-off disc, the end of the tear-off disc facing the stopper being tight on the stopper when the closure is unopened is present and the distance between the latching bead and the second bead corresponds to the smallest distance between the parts of the closure cap surrounding the tear-off disk and the stopper when the closure is unopened.

Um den Stopfen sowohl bei ungeöffnetem als auch bei geöffnetem Verschluss durch die die Abrisscheibe umgebenden Teile der Verschlusskappe in der Flaschenmündung halten zu können, kann das Distanzstück auch mit dem Stopfen einstückig ausgebildet sein, wobei das der Abrisscheibe zugekehrte Ende des Stopfens bei ungeöffnetem Verschluss an der Abrisscheibe dicht ansteht und der Abstand zwischen dem Einrastwulst und dem zweiten Wulst der kleinsten Distanz zwischen den die Abrisscheibe umgebenden Teilen der Verschlusskappe und dem Stopfen bei ungeöffnetem Verschluss entspricht.In order to be able to hold the stopper in the bottle mouth both when the closure is open and when it is open, by means of the parts of the closure cap surrounding the tear-off disc, the spacer can also be formed in one piece with the stopper, the end of the stopper facing the tear-off disc when the closure is unopened Tear-off disc is tight and the distance between the snap-in bead and the second bead corresponds to the smallest distance between the parts of the closure cap surrounding the tear-off disc and the stopper when the closure is unopened.

Der Abstand zwischen dem Einrastwulst und dem zweiten Wulst kann der Breite des Rollrandringes entsprechen. Bei diesem Abstand der beiden Wulste sitzt die Verschlusskappe bei ungeöffnetem Verschluss sicherer auf der Flasche.The distance between the latching bead and the second bead can correspond to the width of the rolled edge ring. At this distance between the two beads, the closure cap sits more securely on the bottle when the closure is not opened.

Im folgenden werden anhand der beiliegenden Zeichnungen Ausführungsbeispiele der Erfindung näher beschrieben. Es zeigen

  • Fig.1 eine pharmazeutische Flasche teilweise im Schnitt mit ungeöffnetem Verschluss und
  • Fig.2 mit geöffnetem Verschluss,
  • Fig.3 eine weitere pharmazeutische Flasche teilweise in Schnitt mit ungeöffnetem Verschluss und
  • Fig.4 mit geöffnetem Verschluss.
Exemplary embodiments of the invention are described in more detail below with reference to the accompanying drawings. Show it
  • 1 shows a pharmaceutical bottle, partly in section, with an unopened closure and
  • Fig. 2 with the closure open,
  • 3 shows another pharmaceutical bottle, partly in section, with an unopened closure and
  • Fig. 4 with the closure open.

Figur 1 zeigt eine Verschlussanordnung für eine pharmazeutische Flasche 1, die beispielsweise eine Injektionsflasche oder eine Transfusionsflasche sein kann. Die Flasche 1 ist durch einen in die Flaschenmündung eingesetzten Stopfen 2 aus Gummi verschlossen. Der Stopfen kann vermittels einer Hohlnadel durchgestochen und das in der Flasche 1 befindliche Medikament durch die Hohlnadel aus der Flasche 1 entnommen werden. Der Stopfen 2 wird aussen durch eine Verschlusskappe 3 umhüllt und geschützt. Die Verschlusskappe 3 umgibt aber auch einen an der Flasche 1 um die Flaschenmündung angeformten Rollrandring 4. Ueber den Stopfen 2 befindet sich eine Abrisscheibe 5, die vor der Oeffnung des Verschlusses über eine Schwächungslinie 6 mit der Verschlusskappe 3 einstückig zusammenhängt. Die Verschlusskappe 3 und die Abrisscheibe 5 bestehen aus Kunststoff, aus Polypropylen.FIG. 1 shows a closure arrangement for a pharmaceutical bottle 1, which can be an injection bottle or a transfusion bottle, for example. The bottle 1 is closed by a rubber plug 2 inserted into the bottle mouth. The stopper can be pierced by means of a hollow needle and the medication located in the bottle 1 can be removed from the bottle 1 through the hollow needle. The plug 2 is enveloped and protected on the outside by a sealing cap 3. However, the closure cap 3 also surrounds a rolled rim ring 4 formed on the bottle 1 around the bottle mouth. Above the stopper 2 there is a tear-off disc 5, which is integrally connected to the closure cap 3 via a weakening line 6 before the closure is opened. The closure cap 3 and the tear-off disc 5 are made of plastic, of polypropylene.

Die Verschlusskappe 3 ist bei ungeöffnetem Verschluss nach Fig.1 am Rollrandring 4 in Richtung der Flasche 1 durch Druck verschiebbar befestigt. Oben steht das dem Stopfen 2 zugekehrte Ende der von der Verschlusskappe 3 durch Druck trennbare Abrisscheibe 5 am Stopfen 2 dicht an. Durch diese Massnahme wird vor der Oeffnung des Verschlusses die Verunreinigung des zum Durchstechen vorgesehenen Teiles des Stopfens 2 verhindert. In der der Flasche abgekehrten Richtung hält der ringförmige Einrastwulst 7 hinter der der Flaschenmündung abgekehrten Kante des Rollrandringes 4 die Verschlusskappe 3 an der Flasche 1 fest.In the case of an unopened closure according to FIG. 1, the closure cap 3 is fastened so that it can be displaced by pressure on the rolled rim ring 4 in the direction of the bottle 1. At the top, the end facing the stopper 2 of the tear-off disk 5, which can be separated by pressure from the closure cap 3, bears tightly against the stopper 2. This measure prevents contamination of the part of the stopper 2 to be pierced before the closure is opened. In the direction facing away from the bottle, the annular latching bead 7 holds the cap 3 on the bottle 1 behind the edge of the rolled rim ring 4 facing away from the bottle mouth.

Zwischen der an der Verschlusskappe 3 bei ungeöffnetem Verschluss über die Schwächungslinie 6 festgehaltene Abrisscheibe 5 und dem darunter liegenden Stopfen 2 ist ein die Umrisslinie der Abrisscheibe 5 nicht überschreitendes Distanzstück vorhanden. Das Distanzstück darf die Umrisslinie der Abrisscheibe 5 nicht überschreiten, damit das Distanzstück durch die nach Entfernung der Abrisscheibe 5 in der Verschlusskappe 3 entstehende Oeffnung durchschlüpfen kann. Das Distanzstück ist in der Anordnung nach Fig.1 mit der Abrisscheibe 5 einstückig ausgebildet.Between the tear-off plate 5 held on the closure cap 3 when the closure is unopened via the weakening line 6 and the stopper 2 underneath there is a spacer which does not exceed the outline of the tear-off plate 5. The spacer must not exceed the outline of the tear-off wheel 5, so that the spacer can be replaced by the The tear-off disk 5 can slip through the opening formed in the closure cap 3. The spacer is formed in one piece with the tear-off disk 5 in the arrangement according to FIG.

In den Figuren 3 und 4 ist eine weitere Verschlussanordnung mit der Flasche 1 dargestellt. Bei dieser Anordnung veschliesst auch ein durchstechbarer, aus Gummi bestehender Stopfen 8 die Flasche 1. Eine Verschlusskappe 9 umgibt bei ungeöffnetem Verschluss den um die Flaschenmündung angeformten Rollrandring 4 und den Stopfen 8. Die Verschlusskappe 9 ist durch den hinter den Rollrandring 4 greifenden Einrastwulst 7 an der Flasche 1 festgehalten. Bei dieser Anordnung ist das bei ungeöffnetem Verschluss zwischen der Abrisscheibe 10 und dem Stopfen 8 liegende Distanzstück mit dem Stopfen 8 einstückig ausgebildet. Es wäre aber auch möglich das Distanzstück teils mit der Abrisscheibe, teils mit dem Stopfen einstückig, oder von beiden unabhängig zu gestalten. Der als Distanzstück dienende Fortsatz des Stopfens 8 steht in Fig.3 an der Abrisscheibe 10 dicht an und verhindert eine allfällige Verunreinigung des zum Durchstechen vorgesehenen Teiles des Stopfens 8. Die Abrisscheibe 10 und die Verschlusskappe 9 sind einstückig aus Kunststoff hergestellt. Die den Stopfen 8 bei ungeöffnetem Verschluss abdeckende Abrisscheibe 10 ist nach Fig.3 an der Verschlusskappe 9 über die Schwächungslinie 11 festgehalten.A further closure arrangement with the bottle 1 is shown in FIGS. 3 and 4. In this arrangement, a pierceable, rubber stopper 8 also closes the bottle 1. When the closure is unopened, a closure cap 9 surrounds the rolled rim ring 4 and the stopper 8 formed around the bottle mouth. The closure cap 9 is attached by the snap bead 7 which engages behind the rolled rim ring 4 the bottle 1 held. In this arrangement, the spacer lying between the tearing disk 10 and the plug 8 when the closure is unopened is formed in one piece with the plug 8. However, it would also be possible to design the spacer partly in one piece with the tear-off disk, partly with the plug, or independently of both. The extension of the stopper 8 serving as a spacer is in close contact with the tear-off disk 10 in FIG. 3 and prevents any contamination of the part of the stopper 8 intended for piercing. The tear-off disk 10 and the closure cap 9 are made in one piece from plastic. According to FIG. 3, the tear-off disk 10 covering the stopper 8 when the closure is unopened is held on the closure cap 9 via the line of weakness 11.

Die in den Figuren 1 bis 4 dargestellten Verschlusskappen 3 und 9 erweitern sich von den Schwächungslinien 6 und 11 aus in der der Flasche 1 abgekehrten Richtung trichterförmig. Die Verschlusskappen 3 und 9 weisen an der Innenseite ihres äusseren, über den Rollrandring 4 reichenden Mantelbereiches einen zweiten, ringförmigen Wulst 12 auf. Der Abstand zwischen dem Einrastwulst 7 und dem zweiten Wulst 12 entspricht in allen Figuren der kleinsten Distanz zwischen den die Abrisscheibe 5 oder 10 umgebenden Teilen der Verschlusskappe 3 oder 9 und dem Stopfen 2 oder 8 bei ungeöffnetem Verschluss nach Fig.1 oder 3. Ausserdem entspricht der Abstand zwischen dem Einrastwulst 7 und dem zweiten Wulst 12 der Breite des Rollrandringes 4. Die Verschlusskappen 3, 9 stützen sich bei ungeöffnetem Verschluss in Richtung der Flasche 1 nicht nur an den Stopfen 2, 8, sondern auch über den zweiten Wulst 12 an der der Flaschenmündung zugekehrten Kante des Rollrandringes 4 ab.The closure caps 3 and 9 shown in FIGS. 1 to 4 expand in a funnel shape from the weakening lines 6 and 11 in the direction facing away from the bottle 1. The sealing caps 3 and 9 have a second, annular bead 12 on the inside of their outer jacket region, which extends over the rolled rim ring 4. The distance between the latching bead 7 and the second bead 12 corresponds in all figures to the smallest distance between the parts of the sealing cap 3 or 9 surrounding the tear-off disk 5 or 10 and the stopper 2 or 8 in the case of an unopened closure according to FIG. 1 or 3 the distance between the latching bead 7 and the second bead 12 the width of the rolled rim ring 4. The closure caps 3, 9 are supported not only on the stopper 2, 8 but also over the second bead 12 on the bottle in the direction of the bottle 1 edge of the rolled rim ring 4 facing the bottle mouth.

Die Funktionsweise der dargestellten Verschlussanordnungen wird nachfolgend beschrieben. Will man den Stopfen 2 der in Fig.1 dargestellten Flasche mit ungeöffnetem Verschluss für das Einstechen einer nicht dargestellten Hohlnadel freilegen, so drückt man mit dem Daumen auf die Verschlusskappe 3, wie es durch die Pfeile 13 in Fig.2 angedeutet ist. Man kann aber die Verschlusskappe 3 auch gegen einen festen Gegenstand drücken, während dem man die Flasche in einer Hand hält. Wenn der Druck genügend hoch ist, reisst die Verbindung zwischen der Verschlusskappe 3 und der Abrisscheibe 5 der Schwächungslinie 6 entlang. Die Abrisscheibe 5 gelangt danach in die trichterförmige Erweiterung der Verschlusskappe 3 und steht an der aus der Richtung der Pfeile 13 anliegenden Druckfläche höchstens nach ihrer Trennung von der Verschlusskappe 3 an. Nach Entfernung der Abrisscheibe 5 mit einer Hand steht die Flasche 1 zur Entnahme eines in der Flasche 1 liegenden Medikamentes mittels Hohlnadel zur Verfügung. Die Verschlusskappe 3 hält dabei den Stopfen 2 in der Flaschenmündung fest, weil nach dem Hineindrücken der Verschlusskappe 3 einerseits der zweite Wulst 12 hinter der der Flaschenmündung abgekehrten Kante des Rollrandringes 4 greift und dort einrastet und anderseits die die Abrisscheibe 5 umgebenden Teile der Verschlusskappe 3 am Stopfen 2 anstehen.The mode of operation of the closure arrangements shown is described below. If you want the stopper 2 of the bottle shown in Figure 1 with an unopened closure for the insertion of a hollow needle, not shown expose, press with your thumb on the cap 3, as indicated by the arrows 13 in Fig.2. But you can also press the cap 3 against a solid object while holding the bottle in one hand. If the pressure is sufficiently high, the connection between the closure cap 3 and the tear-off disk 5 tears along the weakening line 6. The tear-off disc 5 then reaches the funnel-shaped extension of the closure cap 3 and is in contact with the pressure surface lying in the direction of the arrows 13, at most after its separation from the closure cap 3. After removal of the tear-off disk 5 with one hand, the bottle 1 is available for removing a medicament lying in the bottle 1 by means of a hollow needle. The cap 3 holds the stopper 2 in the bottle mouth because, after the cap 3 is pressed in, the second bead 12 on the one hand engages behind the edge of the rolled rim ring 4 facing away from the bottle mouth and engages there, and on the other hand the parts of the cap 3 surrounding the tear-off disc 5 Line stopper 2.

Der Oeffnungsvorgang der in Fig.3 dargestellten, mit Verschluss versehenen Flasche 1 läuft ähnlich ab. Man drückt in der durch die Pfeile 14 in Fig.4 angedeuteten Richtung auf die Verschlusskappe 9, bis sich die Abrisscheibe 10 bei der Schwächungslinie 11 von der Verschlusskappe 9 trennt. Der als Distanzstück dienende Fortsatz des Stopfens 8 ragt danach durch die in der Verschlusskappe 9 frei gewordene Oeffnung. Der Stopfen 8 kann nachher mit einer Hohlnadel durchgestochen und das in der Flasche 1 liegende Medikament entnommen werden. Der Stopfen 8 wird dabei durch die daran anstehenden Teile der Verschlusskappe 9 in der Flaschenmündung festgehalten, weil die Verschlusskappe ihrerseits durch den hinter dem Rollrandring 4 eingerasteten zweiten Wulst 12 an der Flasche 1 gehalten ist.The opening process of the bottle 1 shown in FIG. 3, provided with a closure, proceeds in a similar manner. Press in the direction indicated by the arrows 14 in FIG. 4 on the closure cap 9 until the tear-off disk 10 separates from the closure cap 9 at the line of weakness 11. The extension of the plug 8 serving as a spacer then projects through the opening that has become free in the sealing cap 9. The stopper 8 can subsequently be pierced with a hollow needle and the medication lying in the bottle 1 can be removed. The stopper 8 is held in the bottle mouth by the parts of the closure cap 9 which are in contact with it, because the closure cap is in turn held on the bottle 1 by the second bead 12 which is locked behind the rolled rim ring 4.

Claims (10)

1. Closure arrangement for pharmaceutical bottles (1) with a stopper (2, 8) which closes the bottle mouth and may be pierced by means of a hollow needle for extracting medicaments from the bottle (1) and with a closure cap (3, 9) enclosing a welt ring (4), formed at the bottle (1) around the bottle mouth, and the stopper (2, 8), said closure cap (3, 9) comprising above the stopper (2, 8) a tear-off disc (5, 10) limited by a weakening line (6, 11) and removable upon opening the closure, characterised in that the closure cap (3, 9) is formed of plastics material in one piece with the tear-off disc (5, 10), that the closure cap (3, 9) with the closure in the unopened condition is mounted at the welt ring (4) of the bottle (1) so as to be displaceable by pressure in the axial direction of the bottle (1) from the top downwards, so that due to the pressure on the closure cap (3, 9) the connection between the closure cap (3, 9) and the tear-off disc (5, 10) breaks and the tear-off disc (5, 10) may be removed, and that a spacer is provided between the tear-off disc (5, 10) retained by means of the weakening line (6, 11) at the closure cap (3, 9), with the closure unopened, and the stopper (2, 8) located there below, said spacer not extending beyond the outline of the tear-off disc (5, 10).
2. Closure arrangement according to claim 1, characterised in that the spacer is formed in one piece with the tear-off disc (5) or with the stopper (8).
3. Closure arrangement according to claim 2, characterised in that the spacer is formed in one piece with the tear-off disc (5) and that the end of the tear-off disc (5) facing the stopper (2) sealingly engages with the stopper (2) when the closure is unopened.
4. Closure arrangement according to claim 2, characterised in that the spacer is formed in one piece with the stopper (8) and that the end of the stopper (8) facing the tear-off disc (10) sealingly engages with the tear-off disc (10) when the closure is unopened.
5. Closure arrangement according to any one of claims 1 to 4, characterised in that the closure cap (3, 9) widens in a funnel-shaped manner starting from the weakening line (6, 11) in the direction away from the bottle (1).
6. Closure arrangement according to any one of claims 1 to 5, characterised in that the closure cap (3, 9) comprises at the inner side of its outer jacket region, which extends beyond the welt ring (4), an annular latching bead (7) which, with the closure unopened, engages behind the edge of the welt ring (4), said edge being remote from the bottle mouth.
7. Closure arrangement according to any one of claims 1 to 6, characterised in that the closure cap (3, 9) comprises, at the inner side of its outer jacket region which extends beyond the welt ring (4), a second, annular bead (12).
8. Closure arrangement according to claims 6 and 7, characterised in that the spacer is formed in one piece with the tear-off disc (5), that the end of the tear-off disc (5) facing the stopper (2) sealingly engages with the stopper (2) when the closure is unopened, and that the spacing between the latching bead (7) and the second bead (12) corresponds to the shortest distance between the portions of the closure cap (3) surrounding the tear-off disc (5) and the stopper (2) when the closure is unopened.
9. Closure arrangement according to claims 6 and 7, characterised in that the spacer is formed in one piece with the stopper (8), that the end of the stopper (8) facing the tear-off disc (10) sealingly engages with the tear-off disc 110) when the closure is unopened, and that the spacing between the latching bead (7) and the second bead (12) corresponds to the shortest distance between the portions of the closure cap (3) surrounding the tear-off disc (10) and the stopper (8) when the closure is unopened.
10. Closure arrangement according to claims 6 and 7 or according to one of claims 8 to 9, characterised in that the spacing between the latching bead (7) and the second bead (12) corresponds to the width of the welt ring (4).
EP89111031A 1988-06-28 1989-06-17 Closure for pharmaceutical bottles Expired - Lifetime EP0348762B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT89111031T ATE78779T1 (en) 1988-06-28 1989-06-17 CAP ASSEMBLY FOR PHARMACEUTICAL BOTTLES.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3821674 1988-06-28
DE3821674 1988-06-28
DE3902672 1989-01-30
DE3902672A DE3902672A1 (en) 1988-06-28 1989-01-30 LOCKING ARRANGEMENT FOR PHARMACEUTICAL BOTTLES

Publications (2)

Publication Number Publication Date
EP0348762A1 EP0348762A1 (en) 1990-01-03
EP0348762B1 true EP0348762B1 (en) 1992-07-29

Family

ID=25869514

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89111031A Expired - Lifetime EP0348762B1 (en) 1988-06-28 1989-06-17 Closure for pharmaceutical bottles

Country Status (5)

Country Link
US (1) US5125921A (en)
EP (1) EP0348762B1 (en)
DE (2) DE3902672A1 (en)
DK (1) DK33890A (en)
WO (1) WO1990000141A1 (en)

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Also Published As

Publication number Publication date
DK33890D0 (en) 1990-02-08
DE3902672A1 (en) 1990-02-08
DE58901934D1 (en) 1992-09-03
DK33890A (en) 1990-02-08
WO1990000141A1 (en) 1990-01-11
EP0348762A1 (en) 1990-01-03
US5125921A (en) 1992-06-30

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