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EP0312725B1 - Tropferflasche und Verfahren zu ihrer Herstellung - Google Patents

Tropferflasche und Verfahren zu ihrer Herstellung Download PDF

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Publication number
EP0312725B1
EP0312725B1 EP88113054A EP88113054A EP0312725B1 EP 0312725 B1 EP0312725 B1 EP 0312725B1 EP 88113054 A EP88113054 A EP 88113054A EP 88113054 A EP88113054 A EP 88113054A EP 0312725 B1 EP0312725 B1 EP 0312725B1
Authority
EP
European Patent Office
Prior art keywords
bottle
dropper
section
closure part
discharge direction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP88113054A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0312725A3 (en
EP0312725A2 (de
Inventor
Bernd Dipl.-Ing. Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0312725A2 publication Critical patent/EP0312725A2/de
Publication of EP0312725A3 publication Critical patent/EP0312725A3/de
Application granted granted Critical
Publication of EP0312725B1 publication Critical patent/EP0312725B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers

Definitions

  • the invention relates to a dropper bottle, which has the features of the upper handle of claim 1, and a method for its production.
  • the head of the blow-molded bottle is provided with a calibrated seat, into which an injection molded dropper insert is inserted.
  • a dropper is embedded in the bottle head, which was used in a known manner (DE-OS 30 33 821) instead of a rubber stopper in the bottle head before the latter was formed.
  • a dropper bottle of the type mentioned at the outset is also known (US Pat. No. 2,097,912), the neck of which is designed as a dropper.
  • the channel bounded by the inner wall of the neck initially tapers slightly in the outflow direction, has a constant diameter in a central section and then widens towards the drip edge with a cone angle of more than 90 °.
  • the drop section that widens conically in the outflow direction and an outer conical surface that forms the drip edge together with this conical surface are responsible for the drop formation, the large cone angle of the end section counteracting the surface tension of the liquid and ensuring a uniform supply of liquid to the drip edge.
  • the invention has for its object to provide a dropper bottle that can be easily manufactured and filled sterile, easy to handle when dropping the liquid contained in it reliably keeps the drop size constant and can still be produced inexpensively.
  • the invention is also based on the object of specifying a method for producing such a dropper bottle.
  • Such a dropper bottle because it consists of a heat-sealable plastic and the dropper can be molded together with the bottle, can be as inexpensive as a bottle without a dropper be manufactured and filled sterile.
  • the shape of the channel of the dropper also ensures that the liquid is dispensed in drops of the same size in every inclined position of the dropper bottle. Handling is therefore completely unproblematic.
  • the dropper has a shape according to claim 2.
  • a closure part is advantageously formed on the dropper, since on the one hand the bottle is closed at the earliest possible time and on the other hand there is no danger that the bottle will be opened unintentionally.
  • a predetermined breaking point is preferably provided between the closure part and the bottle neck, as is known per se (US Pat. No. 4,655,355).
  • the closure part is designed according to claim 5, it can be easily broken off with the aid of a closure cap, the predetermined breaking point being able to be designed in such a way that no sharp edges arise. It is also advantageous that no additional tools have to be available to open the bottle.
  • the object of the invention is achieved by the features of claim 6.
  • Both the production of the bottle from a tube made of heat-sealable plastic and the formation of a dropper from a calibrated part of the bottle head are inexpensive work steps.
  • the bottle can be filled between the individual steps used to shape the bottle and its head, so that the method according to the invention allows a sterile container to be produced, filled, molded on and closed in a single operation without additional Parts are needed.
  • a dropper bottle serving as an ampoule for a liquid medicament has, as shown in FIG. 1, a cylindrical bottle body 1, the bottom of which is slightly curved inwards.
  • the bottle head connects centrally to the bottle body 1 with a first cylindrical section 2.
  • a second cylindrical section 3 with a larger diameter which is provided with an external thread 4.
  • a stop bar 5 running parallel to the longitudinal axis of the bottle head is provided.
  • a brake web not shown, is arranged, the length of which, however, is only equal to half the pitch of the external thread 4.
  • the second cylindrical section 3 merges into a third section 6 of the bottle head, the diameter of which is only about half as large as that of the first cylindrical section 2.
  • This third section 6 forms a truncated cone-shaped zone following a cylindrical ring zone, which is against the Free end of the bottle head tapers and forms part of a dropper designated as a whole with 7.
  • the dropper 7, which is formed in one piece with the bottle head, has, following the third section 6, a conical section 8 which widens towards the free end. Not only the outer surface, but also the inner surface of the conical section 8 have a cone angle of about 10 °.
  • the formed by the inner circumferential surface of the conical section 8, calibrated channel 8 ', where it opens into the interior 6' of the third section 6, has a diameter of 0.3 mm in the embodiment.
  • the other end, which is followed by a short inner cone 9 with a cone angle of 60 °, has a diameter of 1.5 mm in the exemplary embodiment.
  • the conical section can also have other dimensions because it is adapted to the desired drop formation in the liquid.
  • connection zone between the closure part 10 and the drop 7 is chosen to be so thin that there is a predetermined breaking point along which the closure part 10 can be separated from the dropper 7 by a rotary movement without sharp edges occurring .
  • a cap 11 which is also made of plastic, is placed on the bottle head and is provided with an internal thread which engages in the external thread 4 of the second cylindrical section 3.
  • the cap 11 tapers in connection with the cylindrical section having the internal thread against the end section comprising the closure part 10, which lies against the outer surface of the closure part 10 and is thereby connected to the closure part 10 in a rotationally fixed manner.
  • the closure part 10 is therefore separated from the dropper 7.
  • the cap can also be designed such that it normally covers the closure part 10. You can then separate the closure part 10 from the dropper 7 by reversely attaching the cap 11 to the closure part 11.
  • the cap in this case has a recess 12 in its end wall, the cross-section of which is adapted to the outer contour of the closure part 10 and overlaps the cap 11 like a ring spanner.
  • the entire bottle is made from an extruded tube made of a heat-sealable plastic.
  • the hose is first made with the help of two Lower mold halves of a device for producing, filling and closing bottles of the bottle body 1 are formed.
  • the first cylindrical section 2 and the second cylindrical section 3 of the head part obtain their final shape with the aid of one jaw each of two head mold halves.
  • the liquid is poured into the bottle body in the desired amount by means of a filling mandrel from which a calibration mandrel protrudes.
  • the mandrel is withdrawn to such an extent that the calibration mandrel lies in the interior of that section of the tube from which the dropper 7 is formed with the aid of calibration jaws which are now moved against one another and thereby form the dropper 7 together with the calibration mandrel.
  • the calibration mandrel is pulled out of the upper end of the hose, then the closure part 10 is formed by means of mold jaws in the head mold halves, thereby closing the bottle and finally fitting the cap 11.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP88113054A 1987-10-23 1988-08-11 Tropferflasche und Verfahren zu ihrer Herstellung Expired - Lifetime EP0312725B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873735909 DE3735909A1 (de) 1987-10-23 1987-10-23 Tropferflasche und verfahren zu ihrer herstellung
DE3735909 1987-10-23

Publications (3)

Publication Number Publication Date
EP0312725A2 EP0312725A2 (de) 1989-04-26
EP0312725A3 EP0312725A3 (en) 1990-03-21
EP0312725B1 true EP0312725B1 (de) 1991-05-08

Family

ID=6338937

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88113054A Expired - Lifetime EP0312725B1 (de) 1987-10-23 1988-08-11 Tropferflasche und Verfahren zu ihrer Herstellung

Country Status (8)

Country Link
US (1) US5076474A (es)
EP (1) EP0312725B1 (es)
JP (1) JPH01146552A (es)
CA (1) CA1333063C (es)
DE (1) DE3735909A1 (es)
ES (1) ES2022554B3 (es)
IN (1) IN170233B (es)
MX (1) MX172829B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886175A (en) * 1989-04-10 1989-12-12 Merck & Co., Inc. Bottle and cap closure system
DE69010597T2 (de) * 1989-09-08 1995-01-26 Merck & Co Inc Tropferspitze für Flüssigkeiten.
FR2653746A1 (fr) * 1989-10-26 1991-05-03 Merck Sharp & Dohme Ensemble de conditionnement sterile permettant de distribuer un liquide par gouttage, et procede de fabrication d'un tel ensemble.
FR2653752A1 (fr) * 1989-10-26 1991-05-03 Merck Sharp & Dohme Ensemble de conditionnement sterile permettant de distribuer un liquide par gouttage, et procede de fabrication d'un tel ensemble.
US5427275A (en) * 1992-09-26 1995-06-27 Hansen; Bernd Dispenser cap with piercer
DE4232305C1 (de) * 1992-09-26 1994-03-31 Bernd Hansen Kappe für Behältnisse, insbesondere Flaschen
US5221017A (en) * 1992-10-13 1993-06-22 Wheaton Holding, Inc. Controlled dropper tip closure
US5358151A (en) * 1993-05-21 1994-10-25 Universal Container Corporation Liquid dropper dispenser
JPH07329994A (ja) * 1994-06-10 1995-12-19 Yoshida Kogyo Kk <Ykk> 多連式並列チューブ及びその製造方法
US5464133A (en) * 1994-09-06 1995-11-07 Drummond; James T. Liquid container having a remotely cleavable seal
US5582330A (en) * 1994-12-28 1996-12-10 Allergan, Inc. Specific volume dispenser
US6571790B1 (en) * 1997-05-12 2003-06-03 Robert E. Weinstein Method and device for organizing and coordinating the combined use of liquid medications for continuous nebulization for the treatment of respiratory disorders
US5918783A (en) * 1997-06-26 1999-07-06 Courtaulds Packaging, Inc. Thermoplastic squeeze tube with self-sealing dispensing orifice
EP1125857B1 (en) * 1999-06-24 2004-01-14 Tuboplast Hispania, S.A. Tube package with tamper-proof cap
KR100544221B1 (ko) 1999-08-17 2006-01-23 산텐 세이야꾸 가부시키가이샤 개구 점안 용기의 제조 방법
US6875201B1 (en) * 1999-08-17 2005-04-05 Santen Pharmaceutical Co., Ltd. Recessed part forming instillation container
MXPA02012127A (es) 2000-06-07 2003-06-06 Loctite R & D Ltd Una instalacion de tobera con una cubierta de desenganche reemplazable, un contenedor que tiene una instalacion de tobera y empaquetamiento para el mismo.
JP4744679B2 (ja) * 2000-08-29 2011-08-10 ライオン株式会社 容器
JP3922910B2 (ja) 2001-10-31 2007-05-30 参天製薬株式会社 段差部を備えた点眼容器
ITMO20020204A1 (it) * 2002-07-16 2004-01-16 Lameplast Spa Recipiente per la confezione di prodotti fluidi o pastosi, particolarmente cosmetici, medicinali e simili
US7114403B2 (en) * 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
WO2005008216A2 (en) * 2003-07-11 2005-01-27 Oakville Hong Kong Co., Limited Sanitary fluid collection, application and storage device and methods of use of same
JP4889498B2 (ja) * 2003-11-14 2012-03-07 アレル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング サンプルの高速分析および保存装置、ならびに使用方法
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
WO2008014709A1 (fr) 2006-07-26 2008-02-07 Abon Biopharm (Hangzhou) Co., Ltd. Dispositif d'analyse d'un échantillon biologique
US20140151322A1 (en) * 2011-04-14 2014-06-05 Sentiss Pharma Private Limited Closure cap for bottle container
US9039985B2 (en) 2011-06-06 2015-05-26 Mks Instruments, Inc. Ozone generator
EP3034428B1 (de) * 2014-12-19 2017-07-19 SHB GmbH Dosierkappe für eine Dosierflasche
CN209321474U (zh) * 2018-11-20 2019-08-30 邹亮 一种精华滴管瓶

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH18751A (de) * 1899-04-12 1900-03-15 Von Maggi S Nahrungsmitteln A Flasche
US2097912A (en) * 1934-06-08 1937-11-02 Merck & Co Inc Bottle neck construction
US2295865A (en) * 1940-11-18 1942-09-15 Rentschler Erwin Container spout
US2800253A (en) * 1952-10-07 1957-07-23 Henderson Edward Drop dispenser and container
US2987223A (en) * 1957-06-06 1961-06-06 Plax Corp Dropper plug
CH347763A (fr) * 1957-08-23 1960-07-15 Neopac Ag Récipient d'une seule pièce en matériau malléable
US3488803A (en) * 1966-06-20 1970-01-13 Beloit Corp System for manufacture of plastic articles
US3777949A (en) * 1969-09-29 1973-12-11 Arias M Chiquiari Improved single dose disposable container and accessories
US3731848A (en) * 1970-04-03 1973-05-08 Shionogi & Co Compartmentalized container
JPS5257510Y2 (es) * 1972-04-06 1977-12-27
JPS4924556U (es) * 1972-05-31 1974-03-02
DE2446564A1 (de) * 1974-09-30 1976-04-08 Barnes Hind Diagnostics Inc Tropfbehaelter mit abbrechbarem verschluss
JPS53136944U (es) * 1977-03-31 1978-10-30
FR2407141A1 (fr) * 1977-10-28 1979-05-25 Cebal Dispositif d'inviolabilite pour recipient dont le goulot est ferme par une capsule vissee
US4358028A (en) * 1980-06-26 1982-11-09 Mercantile & Technical Promotions Inc. Single dose disposable container
DE3033821C2 (de) * 1980-09-09 1982-09-09 Gerhard 7166 Sulzbach-Laufen Hansen Verfahren und Vorrichtung zum Herstellen eines Behälters aus einem heißsiegelbaren Kunststoffschlauch und durch das Verfahren und mittels der Vorrichtung hergestellter Behälter
GB2124992B (en) * 1982-08-03 1986-05-21 Schering Prebbles Ltd Receptacles for releasing medicines at different rates
US4655355A (en) * 1984-12-24 1987-04-07 Baxter Travenol Laboratories, Inc. Container including inner closure with opening permitting free liquid flow
DE8504383U1 (de) * 1985-02-16 1985-03-28 Bayer Ag, 5090 Leverkusen Tubenfoermiger Behaelter
SE458986B (sv) * 1985-03-29 1989-05-29 Draco Ab Dosfoerpackning

Also Published As

Publication number Publication date
JPH01146552A (ja) 1989-06-08
JPH045462B2 (es) 1992-01-31
CA1333063C (en) 1994-11-15
US5076474A (en) 1991-12-31
EP0312725A3 (en) 1990-03-21
IN170233B (es) 1992-02-29
ES2022554B3 (es) 1991-12-01
DE3735909C2 (es) 1991-09-05
MX172829B (es) 1994-01-17
EP0312725A2 (de) 1989-04-26
DE3735909A1 (de) 1989-05-03

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