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EP0300740A3 - Monoclonal antibodies to complement c5a - Google Patents

Monoclonal antibodies to complement c5a Download PDF

Info

Publication number
EP0300740A3
EP0300740A3 EP88306612A EP88306612A EP0300740A3 EP 0300740 A3 EP0300740 A3 EP 0300740A3 EP 88306612 A EP88306612 A EP 88306612A EP 88306612 A EP88306612 A EP 88306612A EP 0300740 A3 EP0300740 A3 EP 0300740A3
Authority
EP
European Patent Office
Prior art keywords
cells
monoclonal antibodies
antibodies
complement
spleen cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP88306612A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0300740A2 (en
Inventor
Ole-Jan Iversen
Kare Bergh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CEFEM AS
Original Assignee
CEFEM AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CEFEM AS filed Critical CEFEM AS
Publication of EP0300740A2 publication Critical patent/EP0300740A2/en
Publication of EP0300740A3 publication Critical patent/EP0300740A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP88306612A 1987-07-20 1988-07-20 Monoclonal antibodies to complement c5a Withdrawn EP0300740A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO873017A NO162210C (no) 1987-07-20 1987-07-20 Monoklonale antistoffer mot c5a for in-vitro anvendelse ved immunologiske kvantitative teknikker eller ved isolering av c5a.
NO873017 1987-07-20

Publications (2)

Publication Number Publication Date
EP0300740A2 EP0300740A2 (en) 1989-01-25
EP0300740A3 true EP0300740A3 (en) 1990-02-07

Family

ID=19890107

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88306612A Withdrawn EP0300740A3 (en) 1987-07-20 1988-07-20 Monoclonal antibodies to complement c5a

Country Status (4)

Country Link
EP (1) EP0300740A3 (no)
DK (1) DK402888A (no)
FI (1) FI883424L (no)
NO (1) NO162210C (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3924924A1 (de) * 1989-07-27 1991-02-07 Goetze Otto Verfahren zum nachweis und/oder der quantitativen bestimmung von komplementpeptid c5a und/oder c5adesarg
DE4118770A1 (de) * 1991-06-07 1992-12-10 Progen Biotechnik Gmbh Verfahren zur herstellung von antikoerpern gegen instabile antigene, antikoerper gegen die aktive form der anaphylatoxine und diese herstellende zellinien und verwendung der antikoerper
DE19913707A1 (de) * 1999-03-26 2000-10-05 Privates Inst Bioserv Gmbh Immunadsorber zur Sepsistherapie
JP2006507834A (ja) 2002-12-02 2006-03-09 レジステンティア ファーマシューティカルズ アーベー 自己ｃ５アミノ酸セグメントおよび非自己アミノ酸セグメントを含むポリペプチドを用いて炎症状態を治療するための方法及び材料
US20080255344A1 (en) * 2004-10-20 2008-10-16 Hans-Werner Heinrich Immuno-Adsorbers For Treatment of Inflammations
CA2766565A1 (en) * 2009-06-23 2010-12-29 Alexion Pharmaceuticals, Inc. Bispecific antibodies that bind to complement proteins

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097440A1 (en) * 1982-06-14 1984-01-04 The Upjohn Company Method and kit for removing and assaying complement system fragments
EP0245993A2 (en) * 1986-04-28 1987-11-19 Cetus Oncology Corporation Monoclonal antibodies against C5A and DES-ARG74-C5A, their production and use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097440A1 (en) * 1982-06-14 1984-01-04 The Upjohn Company Method and kit for removing and assaying complement system fragments
EP0245993A2 (en) * 1986-04-28 1987-11-19 Cetus Oncology Corporation Monoclonal antibodies against C5A and DES-ARG74-C5A, their production and use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Clinical Research, Vol. 35, No. 1, February 1987, page 140A, J.W. LARRICK et al.: "Neutralizing anti-human C5a monoclonal antibodies", whole Abstract. *
Complement, Vol. 3, No. 1, 1986, pages 25-39, S. Karger AG, Basel, CH; M. SCHULZE et al.: "A sensitive ELISA for the quantitation of human C5a in blood plasma using a monoclonal antibody", whole article. *

Also Published As

Publication number Publication date
FI883424A0 (fi) 1988-07-19
NO162210B (no) 1989-08-14
DK402888A (da) 1989-01-21
NO873017L (no) 1989-01-23
DK402888D0 (da) 1988-07-19
NO873017D0 (no) 1987-07-20
FI883424L (fi) 1989-01-21
EP0300740A2 (en) 1989-01-25
NO162210C (no) 1989-11-22

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