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EP0250403A1 - Derives de l-dopa, leur preparation et compositions pharmaceutiques les contenant - Google Patents

Derives de l-dopa, leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
EP0250403A1
EP0250403A1 EP86900721A EP86900721A EP0250403A1 EP 0250403 A1 EP0250403 A1 EP 0250403A1 EP 86900721 A EP86900721 A EP 86900721A EP 86900721 A EP86900721 A EP 86900721A EP 0250403 A1 EP0250403 A1 EP 0250403A1
Authority
EP
European Patent Office
Prior art keywords
dopa
derivative
glycerol
residue
acyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP86900721A
Other languages
German (de)
English (en)
French (fr)
Inventor
Pierre Dumont
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Catholique de Louvain UCL
Original Assignee
Universite Catholique de Louvain UCL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Catholique de Louvain UCL filed Critical Universite Catholique de Louvain UCL
Publication of EP0250403A1 publication Critical patent/EP0250403A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP86900721A 1985-02-04 1986-01-27 Derives de l-dopa, leur preparation et compositions pharmaceutiques les contenant Withdrawn EP0250403A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU85757A LU85757A1 (fr) 1985-02-04 1985-02-04 Derives nouveaux de la l-dopa,procedes pour leur preparation et compositions pharmaceutiques concernant de tels composes
LU85757 1985-02-04

Publications (1)

Publication Number Publication Date
EP0250403A1 true EP0250403A1 (fr) 1988-01-07

Family

ID=19730402

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86900721A Withdrawn EP0250403A1 (fr) 1985-02-04 1986-01-27 Derives de l-dopa, leur preparation et compositions pharmaceutiques les contenant

Country Status (7)

Country Link
EP (1) EP0250403A1 (xx)
JP (1) JPS63501498A (xx)
DK (1) DK437586A (xx)
FI (1) FI871270A7 (xx)
LU (1) LU85757A1 (xx)
NO (1) NO863944L (xx)
WO (1) WO1986004579A1 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19631189A1 (de) * 1996-08-02 1998-02-05 Max Delbrueck Centrum Neuartige kationische Amphiphile für den liposomalen Gentransfer
US7323585B2 (en) 2004-06-04 2008-01-29 Xenoport, Inc. Levodopa prodrugs, and compositions and uses thereof
RU2365580C2 (ru) 2004-06-04 2009-08-27 Ксенопорт, Инк. Пролекарства леводопа, композиции на их основе и их применения
ZA200805511B (en) 2005-12-05 2010-02-24 Xenoport Inc Levodopa prodrug mesylate, compositions thereof, and uses thereof
EP2125702A1 (en) 2006-12-21 2009-12-02 Xenoport, Inc. Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
US7829592B2 (en) 2006-12-21 2010-11-09 Xenoport, Inc. Catechol protected levodopa diester prodrugs, compositions, and methods of use
US8399513B2 (en) 2008-10-20 2013-03-19 Xenoport, Inc. Levodopa prodrug mesylate hydrate
JP2012505885A (ja) 2008-10-20 2012-03-08 ゼノポート，インコーポレーテッド レボドパエステルプロドラッグを合成する方法
GB0904300D0 (en) * 2009-03-12 2009-04-22 Amarin Neuroscience Ltd Essential fatty acid compounds
RU2537137C2 (ru) 2009-11-09 2014-12-27 Ксенопорт, Инк. Фармацевтические композиции и пероральные дозированные формы пролекарства леводопы и способы применения
JP2013043885A (ja) * 2011-08-26 2013-03-04 Kansai Bunri Sogo Gakuen デヒドロアミノ酸含有グリセロール誘導体
JP2018514516A (ja) * 2015-03-30 2018-06-07 ベルリレム ゲーエムベーハー 水溶性ｌ‐ドーパエステル
CA3115162A1 (en) * 2018-10-08 2020-04-16 Cellix Bio Private Limited Compositions and methods for the treatment of parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7605911L (sv) * 1975-06-11 1976-12-12 Merck & Co Inc Forbettrat forfarande for framstellning av estrar av alfa-metyl-3,4-dihydroxifenylalanin
FR2365341A1 (fr) * 1976-09-28 1978-04-21 Synthelabo Derives de l'acide l-(phenyl-3 amino-2 propionyloxy)-2 acetique
GR72800B (xx) * 1979-12-17 1983-12-05 Merck & Co Inc
US4360533A (en) * 1981-12-14 1982-11-23 Merck & Co., Inc. Glyceryl ester of 1-methyl-2-(3,4-dihydroxyphenyl)alanine

Also Published As

Publication number Publication date
DK437586D0 (da) 1986-09-12
WO1986004579A1 (fr) 1986-08-14
NO863944L (no) 1986-12-01
NO863944D0 (no) 1986-10-03
FI871270A0 (fi) 1987-03-23
DK437586A (da) 1986-09-12
LU85757A1 (fr) 1986-09-02
JPS63501498A (ja) 1988-06-09
FI871270A7 (fi) 1987-03-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19861210

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI NL SE

17Q First examination report despatched

Effective date: 19880819

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19881230

RIN1 Information on inventor provided before grant (corrected)

Inventor name: DUMONT, PIERRE