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EP0237259A3 - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
EP0237259A3
EP0237259A3 EP87301870A EP87301870A EP0237259A3 EP 0237259 A3 EP0237259 A3 EP 0237259A3 EP 87301870 A EP87301870 A EP 87301870A EP 87301870 A EP87301870 A EP 87301870A EP 0237259 A3 EP0237259 A3 EP 0237259A3
Authority
EP
European Patent Office
Prior art keywords
detector
path
mass spectrometer
analyzer
quadrupole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP87301870A
Other languages
German (de)
French (fr)
Other versions
EP0237259A2 (en
Inventor
John Edward Philip Syka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Finnigan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finnigan Corp filed Critical Finnigan Corp
Publication of EP0237259A2 publication Critical patent/EP0237259A2/en
Publication of EP0237259A3 publication Critical patent/EP0237259A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/421Mass filters, i.e. deviating unwanted ions without trapping
    • H01J49/4215Quadrupole mass filters
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

A mass spectrometer includes an ion source (11) for projecting ions along a predetermined path, a detector (31, 32, 33) offset from said path, a quadrupole ion filter or analyzer (26) disposed adjacent said detector (31, 32, 33) to provide its output to the detector, and quadrupole means (36) for directing ions away from said path into said ion filter and analyzer (26). Such a spectrometer produces relatively low noise levels.
EP87301870A 1986-03-07 1987-03-04 Mass spectrometer Withdrawn EP0237259A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83760086A 1986-03-07 1986-03-07
US837600 1986-03-07

Publications (2)

Publication Number Publication Date
EP0237259A2 EP0237259A2 (en) 1987-09-16
EP0237259A3 true EP0237259A3 (en) 1989-04-05

Family

ID=25274923

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87301870A Withdrawn EP0237259A3 (en) 1986-03-07 1987-03-04 Mass spectrometer

Country Status (3)

Country Link
EP (1) EP0237259A3 (en)
JP (1) JPS62264546A (en)
CA (1) CA1249381A (en)

Families Citing this family (57)

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GB8826966D0 (en) * 1988-11-18 1988-12-21 Vg Instr Group Plc Gas analyzer
DE3905631A1 (en) * 1989-02-23 1990-08-30 Finnigan Mat Gmbh METHOD FOR THE MASS SPECTROSCOPIC EXAMINATION OF ISOTOPES AND ISOTOPE MASS SPECTROMETERS
FR2648230B1 (en) * 1989-06-12 1991-09-20 Centre Nat Rech Scient METHOD AND DEVICE FOR ANALYZING A SAMPLE BY MASS SPECTROMETRY WITH GOOD ION TRANSMISSION EFFICIENCY
GB9110960D0 (en) * 1991-05-21 1991-07-10 Logicflit Limited Mass spectrometer
JP3620120B2 (en) * 1995-10-27 2005-02-16 株式会社日立製作所 Method and apparatus for mass spectrometry of solutions
US5663560A (en) * 1993-09-20 1997-09-02 Hitachi, Ltd. Method and apparatus for mass analysis of solution sample
JP3367719B2 (en) * 1993-09-20 2003-01-20 株式会社日立製作所 Mass spectrometer and electrostatic lens
US5672868A (en) * 1996-02-16 1997-09-30 Varian Associates, Inc. Mass spectrometer system and method for transporting and analyzing ions
DE19628093B4 (en) * 1996-07-12 2006-09-21 Deutsches Zentrum für Luft- und Raumfahrt e.V. Method and device for detecting sample molecules
DE19629134C1 (en) * 1996-07-19 1997-12-11 Bruker Franzen Analytik Gmbh Device for transferring ions and measuring method carried out with the same
JPH1097838A (en) * 1996-07-30 1998-04-14 Yokogawa Analytical Syst Kk Mass-spectrometer for inductively coupled plasma
US6028308A (en) * 1996-11-18 2000-02-22 Mds Inc. Resolving RF mass spectrometer
WO1998052209A1 (en) * 1997-05-12 1998-11-19 Mds Inc. Rf-only mass spectrometer with auxiliary excitation
AU4326599A (en) * 1998-05-29 1999-12-13 Analytica Of Branford, Inc. Mass spectrometry with multipole ion guides
GB2341270A (en) * 1998-09-02 2000-03-08 Shimadzu Corp Mass spectrometer having ion lens composed of plurality of virtual rods comprising plurality of electrodes
GB9820210D0 (en) 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
US6911650B1 (en) * 1999-08-13 2005-06-28 Bruker Daltonics, Inc. Method and apparatus for multiple frequency multipole
AUPR465101A0 (en) * 2001-04-27 2001-05-24 Varian Australia Pty Ltd "Mass spectrometer"
AU778228B2 (en) * 2001-04-27 2004-11-25 Agilent Technologies Australia (M) Pty Ltd Mass spectrometer including a quadrupole mass analyser arrangement
GB0210930D0 (en) * 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
US6891157B2 (en) * 2002-05-31 2005-05-10 Micromass Uk Limited Mass spectrometer
GB0220571D0 (en) * 2002-09-04 2002-10-09 Micromass Ltd Mass spectrometer
US7429730B2 (en) 2003-11-25 2008-09-30 Syft Technologies Limited SIFT-MS instruments
US7465919B1 (en) * 2006-03-22 2008-12-16 Itt Manufacturing Enterprises, Inc. Ion detection system with neutral noise suppression
US8507850B2 (en) 2007-05-31 2013-08-13 Perkinelmer Health Sciences, Inc. Multipole ion guide interface for reduced background noise in mass spectrometry
CA2699682C (en) * 2007-09-19 2017-05-30 Dh Technologies Development Pte. Ltd. Collision cell for mass spectrometer
JP4978700B2 (en) * 2008-01-30 2012-07-18 株式会社島津製作所 MS / MS mass spectrometer
WO2009095952A1 (en) 2008-01-30 2009-08-06 Shimadzu Corporation Ms/ms mass spectrometer
DE202010017766U1 (en) * 2009-11-17 2012-07-11 Bruker Daltonik Gmbh Use of gas flows in mass spectrometers
JP5686566B2 (en) * 2010-10-08 2015-03-18 株式会社日立ハイテクノロジーズ Mass spectrometer
AU2012225760A1 (en) 2011-03-04 2013-09-19 Perkinelmer Health Sciences, Inc. Electrostatic lenses and systems including the same
US8796638B2 (en) 2011-06-08 2014-08-05 Mks Instruments, Inc. Mass spectrometry for a gas analysis with a two-stage charged particle deflector lens between a charged particle source and a charged particle analyzer both offset from a central axis of the deflector lens
US8450681B2 (en) 2011-06-08 2013-05-28 Mks Instruments, Inc. Mass spectrometry for gas analysis in which both a charged particle source and a charged particle analyzer are offset from an axis of a deflector lens, resulting in reduced baseline signal offsets
US8796620B2 (en) 2011-06-08 2014-08-05 Mks Instruments, Inc. Mass spectrometry for gas analysis with a one-stage charged particle deflector lens between a charged particle source and a charged particle analyzer both offset from a central axis of the deflector lens
CN103650101B (en) * 2011-06-28 2016-06-29 株式会社岛津制作所 Triple quadrupole type quality analysis apparatus
EP2770523A4 (en) * 2011-10-20 2015-05-27 Shimadzu Corp Mass spectrometer
JP6237896B2 (en) * 2014-05-14 2017-11-29 株式会社島津製作所 Mass spectrometer
GB201507363D0 (en) 2015-04-30 2015-06-17 Micromass Uk Ltd And Leco Corp Multi-reflecting TOF mass spectrometer
GB201520134D0 (en) 2015-11-16 2015-12-30 Micromass Uk Ltd And Leco Corp Imaging mass spectrometer
GB201520130D0 (en) 2015-11-16 2015-12-30 Micromass Uk Ltd And Leco Corp Imaging mass spectrometer
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
EP3662502A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Printed circuit ion mirror with compensation
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
WO2019030471A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Ion guide within pulsed converters
EP3662501A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Ion mirror for multi-reflecting mass spectrometers
WO2019030477A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Accelerator for multi-pass mass spectrometers
US11205568B2 (en) 2017-08-06 2021-12-21 Micromass Uk Limited Ion injection into multi-pass mass spectrometers
US10636645B2 (en) * 2018-04-20 2020-04-28 Perkinelmer Health Sciences Canada, Inc. Dual chamber electron impact and chemical ionization source
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201812329D0 (en) * 2018-07-27 2018-09-12 Verenchikov Anatoly Improved ion transfer interace for orthogonal TOF MS
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3410997A (en) * 1964-09-08 1968-11-12 Bell & Howell Co Multipole mass filter
US3473020A (en) * 1967-06-19 1969-10-14 Bell & Howell Co Mass analyzer having series aligned curvilinear and rectilinear analyzer sections
US3487207A (en) * 1967-04-13 1969-12-30 Us Air Force Instrument for varying the angle of incidence between ion beams and a spectrometer
US4234791A (en) * 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
GB2129607A (en) * 1982-10-16 1984-05-16 Finnigan Mat Gmbh Hybrid mass spectrometer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3410997A (en) * 1964-09-08 1968-11-12 Bell & Howell Co Multipole mass filter
US3487207A (en) * 1967-04-13 1969-12-30 Us Air Force Instrument for varying the angle of incidence between ion beams and a spectrometer
US3473020A (en) * 1967-06-19 1969-10-14 Bell & Howell Co Mass analyzer having series aligned curvilinear and rectilinear analyzer sections
US4234791A (en) * 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
GB2129607A (en) * 1982-10-16 1984-05-16 Finnigan Mat Gmbh Hybrid mass spectrometer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF APPLIED PHYSICS, vol. 40, no. 8, July 1969, pages 3127-3134; D.A. CHURCH: "Storage-ring ion trap derived from the linear quadrupole radio-frequency mass filter" *

Also Published As

Publication number Publication date
EP0237259A2 (en) 1987-09-16
CA1249381A (en) 1989-01-24
JPS62264546A (en) 1987-11-17

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Inventor name: SYKA, JOHN EDWARD PHILIP