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EP0105834A3 - Method and apparatus for transferring a fluid sample to microlitre and millilitre aggregates - Google Patents

Method and apparatus for transferring a fluid sample to microlitre and millilitre aggregates Download PDF

Info

Publication number
EP0105834A3
EP0105834A3 EP83810382A EP83810382A EP0105834A3 EP 0105834 A3 EP0105834 A3 EP 0105834A3 EP 83810382 A EP83810382 A EP 83810382A EP 83810382 A EP83810382 A EP 83810382A EP 0105834 A3 EP0105834 A3 EP 0105834A3
Authority
EP
European Patent Office
Prior art keywords
transition
millilitre
microlitre
aggregates
transferring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP83810382A
Other languages
German (de)
French (fr)
Other versions
EP0105834A2 (en
Inventor
Rudolf Oberli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GREINER INSTRUMENTS AG
Original Assignee
Greiner Electronic AG
GREINER INSTRUMENTS AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greiner Electronic AG, GREINER INSTRUMENTS AG filed Critical Greiner Electronic AG
Publication of EP0105834A2 publication Critical patent/EP0105834A2/en
Publication of EP0105834A3 publication Critical patent/EP0105834A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

In einer Kolbenspritze (1) sitzt im Uebergang (8) zwi­ schen Zylinder (2) und Kanüle (4) ein ferromagnetischer Profilkörper (9) mit vielfältigen Funktionen: Beim Einsaugen einer Flüssigkeit verhindert er Turbulenzen im Uebergang (8) und die damit verbundene Bildung von Gasblasen; beim Ausstossen hilft er, Schmutz im Uebergang (8) nach unten wegzuspülen; dazwischen wirkt er durch von aussen veran­ lasste Vertikalbewegungen als Magnetrührer. In a plunger syringe (1) sits in the transition (8) between rule cylinder (2) and cannula (4) a ferromagnetic Profile body (9) with various functions: when sucking in of a liquid, it prevents turbulence in the transition (8) and the associated formation of gas bubbles; at the It helps eject, dirt in the transition (8) down wash away; in between he works through from outside read vertical movements as a magnetic stirrer.

Diese Funktionen werden unterstützt durch eine schräg ansteigende Kolgenstirnfläche (13), im Zusammenwirken mit einer seitlichen Oeffnung (5), welche mit einer Entsorgungs­ einrichtung in Verbindung steht. These functions are supported by an oblique increasing face area (13), in cooperation with a side opening (5), which with a disposal facility is connected.

Hauptanwendung: Schnelles, blasenfreies und daher mengengenaues Uebertragen flüssiger Proben, z.B. Blutplas­ ma, in mehrere Prozessgefässe von Analyseautomaten. Main application: Fast, bubble-free and therefore precise transfer of liquid samples, e.g. Blood plasma ma, in several process vessels of automatic analyzers.

EP83810382A 1982-09-07 1983-08-25 Method and apparatus for transferring a fluid sample to microlitre and millilitre aggregates Withdrawn EP0105834A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH5307/82 1982-09-07
CH530782 1982-09-07

Publications (2)

Publication Number Publication Date
EP0105834A2 EP0105834A2 (en) 1984-04-18
EP0105834A3 true EP0105834A3 (en) 1984-10-10

Family

ID=4291396

Family Applications (1)

Application Number Title Priority Date Filing Date
EP83810382A Withdrawn EP0105834A3 (en) 1982-09-07 1983-08-25 Method and apparatus for transferring a fluid sample to microlitre and millilitre aggregates

Country Status (3)

Country Link
US (1) US4526046A (en)
EP (1) EP0105834A3 (en)
JP (1) JPS5965722A (en)

Families Citing this family (36)

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US4711766A (en) * 1984-07-09 1987-12-08 Standard Oil Company (Indiana) Apparatus for mixing cracking catalyst with a fluid hydrocarbon
US4836037A (en) * 1986-12-16 1989-06-06 Ciba-Geigy Corporation Sample metering valve for a sample preparation system
JP2594635B2 (en) * 1987-03-02 1997-03-26 アイオノード・プロプライアタリイ・リミテツド Mixing device and method
JP2648944B2 (en) * 1988-10-20 1997-09-03 東亜医用電子株式会社 Fluid circuit unit
JP2839560B2 (en) * 1989-07-10 1998-12-16 株式会社日立製作所 Particle suspension mixing device, particle suspension mixing method, and particle measuring device
GB2249171A (en) * 1990-10-25 1992-04-29 N Proizv Ob Biolog Priborostro Liquid sampling
US5627522A (en) * 1992-03-27 1997-05-06 Abbott Laboratories Automated liquid level sensing system
US5960160A (en) * 1992-03-27 1999-09-28 Abbott Laboratories Liquid heater assembly with a pair temperature controlled electric heating elements and a coiled tube therebetween
US5536471A (en) * 1992-03-27 1996-07-16 Abbott Laboratories Syringe with bubble flushing
US5635364A (en) * 1992-03-27 1997-06-03 Abbott Laboratories Assay verification control for an automated analytical system
US5610069A (en) * 1992-03-27 1997-03-11 Abbott Laboratories Apparatus and method for washing clinical apparatus
US5540890A (en) * 1992-03-27 1996-07-30 Abbott Laboratories Capped-closure for a container
US5578494A (en) * 1992-03-27 1996-11-26 Abbott Laboratories Cap actuator for opening and closing a container
US5605665A (en) * 1992-03-27 1997-02-25 Abbott Laboratories Reaction vessel
US6190617B1 (en) 1992-03-27 2001-02-20 Abbott Laboratories Sample container segment assembly
CA2132959C (en) * 1992-03-27 2006-01-24 Apparao Tayi Automated continuous and random access analytical system and components thereof
US5575978A (en) * 1992-03-27 1996-11-19 Abbott Laboratories Sample container segment assembly
US5507410A (en) * 1992-03-27 1996-04-16 Abbott Laboratories Meia cartridge feeder
US5646049A (en) * 1992-03-27 1997-07-08 Abbott Laboratories Scheduling operation of an automated analytical system
US5376313A (en) * 1992-03-27 1994-12-27 Abbott Laboratories Injection molding a plastic assay cuvette having low birefringence
DE4315363C1 (en) * 1993-05-08 1994-10-20 Kernforschungsz Karlsruhe Mixing chamber
JP3115501B2 (en) 1994-06-15 2000-12-11 プレシジョン・システム・サイエンス株式会社 Method for controlling desorption of magnetic material using dispenser and various devices processed by this method
DE4423878A1 (en) * 1994-07-07 1996-01-11 Boehringer Mannheim Gmbh Device and method for separating magnetic microparticles
CN1114831C (en) * 1995-03-20 2003-07-16 准确系统科学株式会社 Method and apparatus for liquid treatment utlizing dispenser
US6759014B2 (en) * 2001-01-26 2004-07-06 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6913934B2 (en) * 1998-08-13 2005-07-05 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6296452B1 (en) 2000-04-28 2001-10-02 Agilent Technologies, Inc. Microfluidic pumping
ATE370799T1 (en) * 2000-05-01 2007-09-15 Fujifilm Corp DEVICE FOR DISPENSING A FLUID
US7335513B2 (en) * 2001-01-26 2008-02-26 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
EP1494814A1 (en) 2002-04-12 2005-01-12 Instrumentation Laboratory Company Immunoassay probe
US7396512B2 (en) 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
FR2972646B1 (en) * 2011-03-14 2015-02-27 Total Sa MIXING A MULTIPHASE FLUID
US9333471B2 (en) * 2012-04-11 2016-05-10 STAT—Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
DE102016225209A1 (en) * 2016-12-15 2018-06-21 Hamilton Bonaduz Ag Pipetting device for improved pulse-like liquid pipetting
CN115155687B (en) * 2022-09-06 2022-11-08 广州达安基因股份有限公司 Quantitative sample adding device and microfluidic detection equipment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2156083A1 (en) * 1971-11-11 1973-05-17 Matti Reunanen METHOD AND DEVICE FOR DOSING OR DEPARTMENT AND IMPLEMENTATION OR REAGENT INCUBATION AND REACTION MIXTURE SAMPLING
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US3972683A (en) * 1974-06-07 1976-08-03 Hycel, Inc. Fluid transfer apparatus
US3985165A (en) * 1975-07-11 1976-10-12 G. D. Searle & Co. Dosing apparatus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US620066A (en) * 1899-02-21 Paul weissgerber
US2129502A (en) * 1935-09-20 1938-09-06 Chicago Television & Res Lab I Liquid distribution apparatus
US3622279A (en) * 1968-06-14 1971-11-23 Hycel Inc Automatic chemical testing apparatus
US3716338A (en) * 1968-06-14 1973-02-13 Hycel Inc Sample fluid dispensing apparatus for chemical testing apparatus
US3864979A (en) * 1973-03-30 1975-02-11 Becton Dickinson Co Blood sedimentation tube barrier
DE2848535C2 (en) * 1978-11-09 1982-12-02 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blood collection device
DK143719C (en) * 1979-01-03 1982-03-08 Radiometer As PROCEDURE FOR BREATHING A LIQUIDIZING PUMP PUMP AND PUMP PUMP WITH AN ARRANGEMENT FOR USE IN EXERCISE THE PROCEDURE
JPS58129366A (en) * 1982-01-29 1983-08-02 Olympus Optical Co Ltd Distributive injection

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2156083A1 (en) * 1971-11-11 1973-05-17 Matti Reunanen METHOD AND DEVICE FOR DOSING OR DEPARTMENT AND IMPLEMENTATION OR REAGENT INCUBATION AND REACTION MIXTURE SAMPLING
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US3972683A (en) * 1974-06-07 1976-08-03 Hycel, Inc. Fluid transfer apparatus
US3985165A (en) * 1975-07-11 1976-10-12 G. D. Searle & Co. Dosing apparatus

Also Published As

Publication number Publication date
US4526046A (en) 1985-07-02
JPS5965722A (en) 1984-04-14
EP0105834A2 (en) 1984-04-18

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

PUAL Search report despatched

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AK Designated contracting states

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19850329

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GREINER INSTRUMENTS AG

17Q First examination report despatched

Effective date: 19860703

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19861114

RIN1 Information on inventor provided before grant (corrected)

Inventor name: OBERLI, RUDOLF