EP0079346A1 - Temperature regulator for human scalp - Google Patents
Temperature regulator for human scalpInfo
- Publication number
- EP0079346A1 EP0079346A1 EP82901489A EP82901489A EP0079346A1 EP 0079346 A1 EP0079346 A1 EP 0079346A1 EP 82901489 A EP82901489 A EP 82901489A EP 82901489 A EP82901489 A EP 82901489A EP 0079346 A1 EP0079346 A1 EP 0079346A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cap
- cavity
- fluid
- inlets
- outlets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004761 scalp Anatomy 0.000 title claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 17
- 238000011282 treatment Methods 0.000 claims abstract description 17
- 238000002512 chemotherapy Methods 0.000 claims abstract description 15
- 210000003128 head Anatomy 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 6
- 230000003658 preventing hair loss Effects 0.000 claims abstract description 6
- 239000012530 fluid Substances 0.000 claims description 21
- 230000002631 hypothermal effect Effects 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 210000004209 hair Anatomy 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 239000003814 drug Substances 0.000 description 8
- 230000003676 hair loss Effects 0.000 description 6
- 208000024963 hair loss Diseases 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- MWWSFMDVAYGXBV-RUELKSSGSA-N Doxorubicin hydrochloride Chemical compound Cl.O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 MWWSFMDVAYGXBV-RUELKSSGSA-N 0.000 description 3
- 229960002918 doxorubicin hydrochloride Drugs 0.000 description 3
- 210000003780 hair follicle Anatomy 0.000 description 3
- 231100000360 alopecia Toxicity 0.000 description 2
- 230000004700 cellular uptake Effects 0.000 description 2
- 208000020401 Depressive disease Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010047139 Vasoconstriction Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000003762 total hair loss Effects 0.000 description 1
- 230000025033 vasoconstriction Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/10—Cooling bags, e.g. ice-bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
- A61F2007/0002—Head or parts thereof
- A61F2007/0008—Scalp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
Definitions
- the present invention relates to a method and apparatus for preventing hair loss, in patients undergoing chemo-therapy treatment, with scalp hypothermia..
- the present invention seeks to ameliorate these disadvantages or at the very least to provide a choice of preventive measures.
- the method aspect of the present invention provides a 3 5 method of preventing hair-loss in patients undergoing chemo-therapy treatment with scalp hypothermia which comprises positioning a cap formed of flexible impervious material on the head of a patient so as to cover the patient's hair, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and circulating a fluid through said cavity to maintain the patient's scalp temperature to between 0°C and 5°C for a period of between 40 and 120 minutes.
- the apparatus aspect of the present invention provides an apparatus comprising a cap formed of flexible impervious material, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and having a vent tube connected to one outlet to permit the evacuation -of air from said cavity and to prevent a syphoning effect occurring in the outlet.
- the cavity is filled with an externally temperature regulated fluid admitted to the cavity via five inlet ports and, after circulating throughout the said cavity, the said ' fluid is removed via 10 outlet ports to a water/ice reservoir where it is cooled and returned to the cap by means of a known pump.
- the circulating fluid reduces the temperature for as long as scalp hypothermia is required.
- the cap device of the present invention effectively restricts the flow of blood to the hair follicles through constricting the blood vessels by reducing the temperature thereof and by applying pressure thereto by means of the fluid-filled cap.
- scalp hypothermia is critical to ensure that no drugs reach or are taken up by the hair follicles.
- the temperature of the scalp should be reduced ten minutes 5 prior to beginning chemo-therapy treatment and scalp hypothermia maintained for preferably 90 minutes. These times are presently used; however, it is to be understood that the present invention encompasses such variations in time of use and temperature of fluid used as may be 10 required through the use of drugs other than doxorubicin hydrochloride in chemo-therapy treatment.
- the preferred embodiment of the present invention is adapted to be suspended from a hook above the patients' head to relieve 15 the weight of the fluid-filled cap.
- Figure 1 is a schematic view of the cap in position on ' a patient ' .
- the cap' 20 identified generally by the reference (1) is formed of an inner lining (2) and an outer lining (3) formed of any suitable impervious material, for example flexible rubber.
- the peripheries of the linings are sealed together as indicated at (4) , thereby forming a cavity (5) within the 25 cap.
- the cap as illustrated is provided with a number of inlets and outlets to the cavity (5) .
- These inlets comprise tubes (6) , (7) , (8) and (9) connected to ports (10) , (11) and (12) located in the forehead region and , 30 right temple region of cap.
- ports (10) , (11) and (12) located in the forehead region and , 30 right temple region of cap.
- ports _ (13) and (14) are two further ports _ (13) and (14) (not shown) in the left temple region of the cap which mirror ports (11) and (12) respectively.
- outlets comprise tubes (15) , (16) , (17) , (18) , (19) and (20) connected to ports (21) and (22) and (23) , 35 (24) , (25) and (26) located in the upper front region, the crown region and the lower rear region of the cap respectively.
- outlet port (21) are important as they directly affect the pressure of the fluid inside the cap.
- the pressure gradient between the cap and the water/ice reservoir alters whenever the cap is worn at different heights by different patients.
- the height of port (21) marked (A) in the drawing directly affects the internal pressure of the fluid within the cavity. Increasing the dimension (A) increases the internal pressure and decreasing the dimension A correspondingly decreases the internal pressure. Preferred dimensions of (A) are 3.5cm * and of B are 1cm..
- vent tube (27 with stopper (28) .
- This vent tube acts ' initially to evacuate air from the said cavity whilst the cavity is filling with fluid via said inlets and later acts to permit air to enter outlet tube 15 thereby overcoming any syphoning effect caused by the fluid exiting from outlet port (21) .
- the said inlet tubes converge and join a common single inlet pipe (29) which is connected to an immersible pump immersed in the water/ice reservoir.
- the immersible pump and the water/ice reservoir are known and are not shown in the drawing for reason of clarity.
- the said outlet tubes also converge and join a common single outlet pipe (30) which discharges into said water/ice reservoir.
- An optional feature of the invention is an attachment means (31) arid strap (32) by which the cap can be suspended from a hook above the patient to thereby alleviate the ft weight of the cap when it is filled with fluid.
- This 5 attachment means is particularly advantageous when the patient is elderly or weak.
- Example 2 20 Female aged 53. Hair condition medium sparse 400mm length. Previously undergone chemo-therapy treatment with accompanying total loss of hair on that previous occasion. Method of invention as for Example 1 except total time of treatment 70 minutes. (Same chemical mixture as with 25 previous chemo-therapy treatment.)
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Procede et appareil empechant les chutes de cheveux chez des sujets soumis a un traitement de chimiotherapie. Le procede consiste a placer un bonnet (1) sur la tete d'un sujet et a faire circuler au travers d'une cavite (5) un liquide froid pour reduire et maintenir la temperature du cuir chevelu du sujet entre 0 C et 5 C pendant une periode de 40 a 120 minutes. Le bonnet (1) consiste en un materiau impermeable flexible et possede une doublure interieure (2) et une doublure exterieure (3) scellees ensemble a leurs peripheries formant ainsi une cavite (5) ayant des orifices d'entree (10)- (14) et des orifices de sortie (21)- (26) pour permettre au liquide froid de circuler.Method and apparatus for preventing hair loss in subjects undergoing chemotherapy treatment. The method consists in placing a cap (1) on the head of a subject and in circulating through a cavity (5) a cold liquid to reduce and maintain the temperature of the scalp of the subject between 0 C and 5 C for a period of 40 to 120 minutes. The cap (1) consists of a flexible waterproof material and has an inner lining (2) and an outer lining (3) sealed together at their peripheries thus forming a cavity (5) having inlet openings (10) - (14 ) and outlet openings (21) - (26) to allow cold liquid to circulate.
Description
mPΕRX∑mE ΗBGULASOR POR HUMAN SCALP The present invention relates to a method and apparatus for preventing hair loss, in patients undergoing chemo-therapy treatment, with scalp hypothermia..
-4f In the treatment of cancer patients by cherao-therapy 5 the use of the drug doxorubicin hydrochloride is known to cause alopecia, i.e. hair loss, in patients. The psychological impact of this drug-induced side effect in some instances leads patients to refuse chemo-therapy and in other instances results in acute depression in patients 10 undergoing chemo-therapy treatment.
Several methods are presently in use to alleviate the drug-induced alopecia with scalp hypothermia, ranging from simply covering the patients1 head in bags of crushed ice held in place by means of bandages, to caps containing 15 packs of ice or chemical coolants. All of these known methods suffer from some disadvantages inter alia: they have poor temperature distribution, they are cumbersome in use, they have limited effective cooling life, they provide less than 100% effective scalp cover; with the result that 20 no known method is completely satisfactory.
The present invention seeks to ameliorate these disadvantages or at the very least to provide a choice of preventive measures.
Two advantages are understood to accrue from scalp 25 hypothermia: firstly the vasoconstriction induced by temperature fall should act to reduce the drug quantities 'reaching the hair follicles, and secondly cellular uptake of the drug should be reduced (like many other drugs, doxorubicin hydrochloride requires temperature-dependant
-B0 metabollic processes for cellular uptake) . /_ According to the present invention there is provided a method and apparatus for preventing hair loss in patients undergoing chemo-therapy treatment.
The method aspect of the present invention provides a 35 method of preventing hair-loss in patients undergoing chemo-therapy treatment with scalp hypothermia which
comprises positioning a cap formed of flexible impervious material on the head of a patient so as to cover the patient's hair, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and circulating a fluid through said cavity to maintain the patient's scalp temperature to between 0°C and 5°C for a period of between 40 and 120 minutes.
The apparatus aspect of the present invention provides an apparatus comprising a cap formed of flexible impervious material, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and having a vent tube connected to one outlet to permit the evacuation -of air from said cavity and to prevent a syphoning effect occurring in the outlet.
In one preferred embodiment of the invention, the cavity is filled with an externally temperature regulated fluid admitted to the cavity via five inlet ports and, after circulating throughout the said cavity, the said 'fluid is removed via 10 outlet ports to a water/ice reservoir where it is cooled and returned to the cap by means of a known pump. The circulating fluid reduces the temperature for as long as scalp hypothermia is required. The cap device of the present invention effectively restricts the flow of blood to the hair follicles through constricting the blood vessels by reducing the temperature thereof and by applying pressure thereto by means of the fluid-filled cap.
-βURfcAϋ-
It -has been found that the duration of scalp hypothermia is critical to ensure that no drugs reach or are taken up by the hair follicles. Preferably the temperature of the scalp should be reduced ten minutes 5 prior to beginning chemo-therapy treatment and scalp hypothermia maintained for preferably 90 minutes. These times are presently used; however, it is to be understood that the present invention encompasses such variations in time of use and temperature of fluid used as may be 10 required through the use of drugs other than doxorubicin hydrochloride in chemo-therapy treatment.
For patients that are elderly or weak the preferred embodiment of the present invention is adapted to be suspended from a hook above the patients' head to relieve 15 the weight of the fluid-filled cap.
The invention will now be further described with reference to the preferred embodiment and to the . accompanying drawing, in which: Figure 1 is a schematic view of the cap in position on' a patient'. The cap' 20 identified generally by the reference (1) is formed of an inner lining (2) and an outer lining (3) formed of any suitable impervious material, for example flexible rubber. The peripheries of the linings are sealed together as indicated at (4) , thereby forming a cavity (5) within the 25 cap.
The cap as illustrated is provided with a number of inlets and outlets to the cavity (5) . These inlets comprise tubes (6) , (7) , (8) and (9) connected to ports (10) , (11) and (12) located in the forehead region and , 30 right temple region of cap. There are two further ports _ (13) and (14) (not shown) in the left temple region of the cap which mirror ports (11) and (12) respectively.
These outlets comprise tubes (15) , (16) , (17) , (18) , (19) and (20) connected to ports (21) and (22) and (23) , 35 (24) , (25) and (26) located in the upper front region, the crown region and the lower rear region of the cap
respectively. There are four additional tubes and four additional ports (not shown) which are mirrored by outlet tubes (17)-(20) and outlet ports (23)-(26) respectively.
It has been discovered that the dimensions of outlet port (21) are important as they directly affect the pressure of the fluid inside the cap. The pressure gradient between the cap and the water/ice reservoir alters whenever the cap is worn at different heights by different patients. In order to minimise these changes in pressure, it is important to ensure that the internal diameter of port (21) marked (B) in the drawing is large enough to remove at least one half of the fluid circulating within the cavity at any given time.
The height of port (21) marked (A) in the drawing, directly affects the internal pressure of the fluid within the cavity. Increasing the dimension (A) increases the internal pressure and decreasing the dimension A correspondingly decreases the internal pressure. Preferred dimensions of (A) are 3.5cm*and of B are 1cm..
Also shown in the drawing is a vent tube (27 with stopper (28) . This vent tube, without stopper, acts ' initially to evacuate air from the said cavity whilst the cavity is filling with fluid via said inlets and later acts to permit air to enter outlet tube 15 thereby overcoming any syphoning effect caused by the fluid exiting from outlet port (21) .
The said inlet tubes converge and join a common single inlet pipe (29) which is connected to an immersible pump immersed in the water/ice reservoir. The immersible pump and the water/ice reservoir are known and are not shown in the drawing for reason of clarity. The said outlet tubes also converge and join a common single outlet pipe (30) which discharges into said water/ice reservoir.
The left side of the cap is identical to the right side and for clarity only the right-hand side has now been discussed.
An optional feature of the invention is an attachment means (31) arid strap (32) by which the cap can be suspended from a hook above the patient to thereby alleviate the ft weight of the cap when it is filled with fluid. This 5 attachment means is particularly advantageous when the patient is elderly or weak.
The apparatus and method of the present invention has been used on actual patients undergoing chemo-therapy treatment as set out in the following examples: 10 Example 1:
Female aged 62. Hair medium length of approximately 125 mm. Previously undergone two chemo-therapy treatments with total loss of hair on both occasions. Cap of present invention positioned on head 10 minutes prior to beginning 15 chemo-therapy treatment (with same chemical mixture) . Temperature of fluid maintained at 1. °C. Scalp hypothermia continued for total time of 60 minutes. On follow up of patient - no detectable hair loss. Example 2: 20 Female aged 53. Hair condition medium sparse 400mm length. Previously undergone chemo-therapy treatment with accompanying total loss of hair on that previous occasion. Method of invention as for Example 1 except total time of treatment 70 minutes. (Same chemical mixture as with 25 previous chemo-therapy treatment.)
On follow up of patient - no detectable hair loss. Example 3:
Female aged 62. Hair thick and curly. Previously experienced total hair loss with same chemical mixture. 3 Method of invention as for Example 1 except total time of f 4 treatment 80 minutes. On follow up of patient - no detectable hair loss.
'BϋKtATT
Claims
1. A method of preventing hair loss in patients undergoing chemo-therapy treatment with scalp hypothermia which comprises positioning a cap formed of flexible impervious material on the head of a patient so as to cover the patient's hair, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and circulating a fluid through said cavity to maintain the patient's scalp temperature to between 0°C and 5°C for a period of between 40 and 120 minutes.
2. A method as claimed in claim 1 wherein said treatment is continued for a period of 60 to 90 minutes.
3. A method as claimed in claims 1 or 2 wherein said fluid is a water/ice mixture.
4. A cap used for scalp hypothermia said cap being formed of flexible impervious material, said cap being formed of an inner and an outer lining sealed together around their peripheries and thereby forming a cavity within said cap, said cavity being provided with at least two inlets and two outlets so spaced from each other as to permit fluid admitted to said cavity to circulate there throughout and having a vent tube connected to one outlet to permit the evacuation of air from said cavity and to prevent a syphoning effect occurring in the outlet.
5. A cap as claimed in claim 4 wherein the front outlet port is larger than the rear outlet ports said front outlet port being of diameter 1cm and height 3.5cm and capable of removing at least one half of the volume of fluid circulating within said cavity at any given time.
6. A cap as claimed in claims 4 and 5 wherein said inlets are connected to a common source of supply and said outlets are connected to a common discharge member.
7. A cap as claimed in claim 6 wherein the cap is provided with 5 inlets and 10 outlets.
8. A cap substantially as described with reference to the
A accompanying drawing.
9. A method of preventing hair loss in patients undergoing chemo-therapy substantially as hereinbefore described with reference to the accompanying drawing.
_
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU9014/81 | 1981-05-25 | ||
| AUPE901481 | 1981-05-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0079346A1 true EP0079346A1 (en) | 1983-05-25 |
| EP0079346A4 EP0079346A4 (en) | 1985-02-28 |
Family
ID=3769080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19820901489 Withdrawn EP0079346A4 (en) | 1981-05-25 | 1982-05-25 | Temperature regulator for human scalp. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0079346A4 (en) |
| JP (1) | JPS58500790A (en) |
| AU (1) | AU8412082A (en) |
| WO (1) | WO1982004184A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4566455A (en) * | 1984-03-27 | 1986-01-28 | H. Mervin Hughes, II | Skin temperature control |
| US5342411A (en) * | 1988-04-16 | 1994-08-30 | Greater Glasgow Health Board | Scalp cooling device |
| GB8809029D0 (en) * | 1988-04-16 | 1988-05-18 | Scalp cooling apparatus | |
| NL193581C (en) * | 1990-03-30 | 2000-03-02 | Leuven K U Res & Dev | Hood designed for cooling the head. |
| US6277143B1 (en) | 1991-05-22 | 2001-08-21 | Life Science Holdings, Inc. | Brain cooling apparatus and method for cooling the brain |
| US6030412A (en) * | 1991-05-22 | 2000-02-29 | Life Science Holdings, Inc. | Apparatus and method for cooling the brain, brain stem and associated neurologic tissues |
| US5261399A (en) * | 1991-05-22 | 1993-11-16 | Klatz Ronald M | Brain cooling device and method for performing the same |
| SE506911C2 (en) * | 1996-10-17 | 1998-03-02 | Yvonne Olofsson | Device for controlled scalp tempering |
| US9119705B2 (en) | 1998-06-08 | 2015-09-01 | Thermotek, Inc. | Method and system for thermal and compression therapy relative to the prevention of deep vein thrombosis |
| US6312453B1 (en) | 1998-07-16 | 2001-11-06 | Olympic Medical Corp. | Device for cooling infant's brain |
| AU8828498A (en) | 1998-08-14 | 2000-03-06 | Life Science Holdings, Inc. | Apparatus and method for cooling the brain, brain stem and associated neurologic tissues |
| US7008445B2 (en) | 2002-04-29 | 2006-03-07 | Medcool, Inc. | Method and device for rapidly inducing hypothermia |
| US7052509B2 (en) | 2002-04-29 | 2006-05-30 | Medcool, Inc. | Method and device for rapidly inducing and then maintaining hypothermia |
| EP1581154A4 (en) * | 2002-12-12 | 2007-10-03 | Medcool Inc | Method and device for rapidly inducing and then maintaining hypothermia |
| US8128672B2 (en) | 2006-05-09 | 2012-03-06 | Thermotek, Inc. | Wound care method and system with one or both of vacuum-light therapy and thermally augmented oxygenation |
| US8574278B2 (en) | 2006-05-09 | 2013-11-05 | Thermotek, Inc. | Wound care method and system with one or both of vacuum-light therapy and thermally augmented oxygenation |
| US10765785B2 (en) | 2004-07-19 | 2020-09-08 | Thermotek, Inc. | Wound care and infusion method and system utilizing a therapeutic agent |
| US10016583B2 (en) | 2013-03-11 | 2018-07-10 | Thermotek, Inc. | Wound care and infusion method and system utilizing a thermally-treated therapeutic agent |
| US9101463B2 (en) * | 2007-02-15 | 2015-08-11 | Dignitana Ab | Head cooler |
| US10512587B2 (en) | 2011-07-27 | 2019-12-24 | Thermotek, Inc. | Method and apparatus for scalp thermal treatment |
| CN104224433A (en) * | 2014-09-24 | 2014-12-24 | 河南科技大学第一附属医院 | Medical ice cap |
| US10478637B2 (en) | 2015-04-30 | 2019-11-19 | Hair Science Systems Llc | System and method for limiting chemotherapy-induced alopecia |
| BR202017017374Y1 (en) * | 2017-08-14 | 2022-09-27 | Gianmaria Cominato Filho | DISPOSITION APPLIED IN CAP FOR THE COOLING OF HAIR LEATHER |
| CN113041015B (en) * | 2021-03-01 | 2022-05-24 | 中南大学湘雅医院 | Clinical head cooling device for neurosurgery |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1388621A (en) * | 1919-09-08 | 1921-08-23 | Umbsen Mfg Corp | Device for treating the eyes |
| US1529464A (en) * | 1922-07-01 | 1925-03-10 | John L Cox | Medical belt or bandage |
| US1896953A (en) * | 1931-05-18 | 1933-02-07 | Hassell Cecil Starke | Electric ice cap |
| US1991784A (en) * | 1932-07-28 | 1935-02-19 | Charles A Bohemier | Refrigerant applicator |
| GB446788A (en) * | 1934-05-08 | 1936-05-06 | S N I M Sa | Improvements relating to surgical cooling or heating appliances |
| GB455283A (en) * | 1935-04-15 | 1936-10-15 | James Le Gallais Thelland | Improvements in cooling means for wearing apparel and wrappers of fabric material |
| GB460358A (en) * | 1936-08-12 | 1937-01-26 | Edward Pomeranz | Improvements relating to surgical head-cooling devices |
| US2250325A (en) * | 1938-10-12 | 1941-07-22 | Eugene L Barnes | Thermal device |
| US3606890A (en) * | 1969-07-09 | 1971-09-21 | Walter Gilbert | Beauty treatment apparatus |
| US4138743A (en) * | 1975-02-25 | 1979-02-13 | Acurex Corporation | Liquid cooled helmet |
| US4059852A (en) * | 1976-05-24 | 1977-11-29 | Crane Stanley J | Inflatable suit for cyclists |
| US4259961A (en) * | 1979-01-24 | 1981-04-07 | Hood Iii Andrew G | Cooling pad |
-
1981
- 1981-05-25 AU AU84120/82A patent/AU8412082A/en not_active Abandoned
-
1982
- 1982-05-25 JP JP57501560A patent/JPS58500790A/en active Pending
- 1982-05-25 EP EP19820901489 patent/EP0079346A4/en not_active Withdrawn
- 1982-05-25 WO PCT/AU1982/000082 patent/WO1982004184A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1982004184A1 (en) | 1982-12-09 |
| JPS58500790A (en) | 1983-05-19 |
| AU8412082A (en) | 1982-12-02 |
| EP0079346A4 (en) | 1985-02-28 |
Similar Documents
| Publication | Publication Date | Title |
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