EG19674A - Antiviral tetrahydroimidazol (1,4) denzodiazepin -2-thiones - Google Patents

Antiviral tetrahydroimidazol (1,4) denzodiazepin -2-thiones

Info

Publication number: EG19674A
Authority: EG; Egypt
Prior art keywords: denzodiazepin; tetrahydroimidazol; thiones; antiviral; antiviral tetrahydroimidazol
Prior art date: 1989-02-23

Application number

EG11190A

Other languages

English (en)

Inventor

Michael J Kukla

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1990-02-21

Publication date

1996-06-30

1989-02-23 Priority claimed from GB898904108A external-priority patent/GB8904108D0/en

1989-09-08 Priority claimed from GB898920354A external-priority patent/GB8920354D0/en

1990-02-21 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1996-06-30 Application granted granted Critical

1996-06-30 Publication of EG19674A publication Critical patent/EG19674A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EG11190A 1989-02-23 1990-02-21 Antiviral tetrahydroimidazol (1,4) denzodiazepin -2-thiones EG19674A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB898904108A GB8904108D0 (en)	1989-02-23	1989-02-23	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
GB898920354A GB8920354D0 (en)	1989-09-08	1989-09-08	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
US40662689A	1989-09-13	1989-09-13

Publications (1)

Publication Number	Publication Date
EG19674A true EG19674A (en)	1996-06-30

Family

ID=27264337

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG11190A EG19674A (en)	1989-02-23	1990-02-21	Antiviral tetrahydroimidazol (1,4) denzodiazepin -2-thiones

Country Status (28)

Country	Link
EP (1)	EP0384522B1 (sh)
JP (1)	JP2588624B2 (sh)
AP (1)	AP139A (sh)
AT (1)	ATE84534T1 (sh)
AU (1)	AU617926B2 (sh)
CA (1)	CA2010639C (sh)
CY (1)	CY1868A (sh)
DE (1)	DE69000743T2 (sh)
DK (1)	DK0384522T3 (sh)
EG (1)	EG19674A (sh)
ES (1)	ES2046671T3 (sh)
FI (1)	FI92830C (sh)
GR (1)	GR3006855T3 (sh)
HK (1)	HK114995A (sh)
HU (2)	HU204831B (sh)
IE (1)	IE63155B1 (sh)
IL (1)	IL93136A (sh)
JO (1)	JO1610B1 (sh)
LV (1)	LV5782B4 (sh)
MA (1)	MA21748A1 (sh)
MY (1)	MY106231A (sh)
NO (1)	NO173503C (sh)
NZ (1)	NZ232548A (sh)
OA (1)	OA09196A (sh)
PH (1)	PH27113A (sh)
PT (1)	PT93227B (sh)
TN (1)	TNSN90021A1 (sh)
YU (1)	YU47219B (sh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8806449D0 (en) *	1988-03-18	1988-04-20	Janssen Pharmaceutica Nv	Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
NZ235137A (en) *	1989-09-13	1992-02-25	Janssen Pharmaceutica Nv	Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
NZ238664A (en) *	1990-07-06	1992-12-23	Janssen Pharmaceutica Nv	Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
DE4036552C1 (sh) *	1990-11-16	1992-02-06	Boehringer Mannheim Gmbh, 6800 Mannheim, De
DE4103803A1 (de) *	1991-02-08	1992-08-13	Boehringer Mannheim Gmbh	Neue 4,5,6,7-tetrahydro-imidazo-(4,5,ljk)(1,4)- benzodiazepin-2-(1h)-thione, verfahren zu ihrer herstellung sowie arzneimittel und zwischenprodukte zur herstellung dieser verbindungen
GB9109557D0 (en) *	1991-05-02	1991-06-26	Wellcome Found	Chemical compounds
ES2083668T5 (es) *	1991-05-16	2001-06-16	Glaxo Group Ltd	Combinaciones antiviricas que contienen analogos de nucleosido.
US5593993A (en) *	1991-08-02	1997-01-14	Medivir Ab	Method for inhibition of HIV related viruses
IL102548A (en) *	1991-08-02	1998-08-16	Medivir Ab	Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds
US5463049A (en) *	1991-09-24	1995-10-31	Janssen Pharmaceutica N.V.	Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones
ATE184787T1 (de) *	1992-05-13	1999-10-15	Wellcome Found	Therapeutische kombinationen
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
GR920100326A (el) *	1992-07-21	1994-03-31	Medivir Ag	Ενώσεις και μέ?οδοι αναστολής του HIV και των σχετικών ιών.
US5519021A (en) *	1992-08-07	1996-05-21	Merck & Co., Inc.	Benzoxazinones as inhibitors of HIV reverse transcriptase
DE19946289A1 (de) *	1999-09-28	2001-03-29	Basf Ag	Benzodiazepin-Derivate, deren Herstellung und Anwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4075206A (en) *	1977-02-25	1978-02-21	Eli Lilly And Company	Substituted pyrroloquinoxalinones and diones
FR2534257A1 (fr) *	1982-10-12	1984-04-13	Roussel Uclaf	Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
GB8333581D0 (en) *	1983-12-16	1984-01-25	Wyeth John & Brother Ltd	Heterocyclic compounds
GB8806449D0 (en) *	1988-03-18	1988-04-20	Janssen Pharmaceutica Nv	Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

1990
- 1990-01-23 IL IL9313690A patent/IL93136A/en not_active IP Right Cessation
- 1990-02-06 MY MYPI90000182A patent/MY106231A/en unknown
- 1990-02-14 NZ NZ232548A patent/NZ232548A/en unknown
- 1990-02-16 AT AT90200348T patent/ATE84534T1/de not_active IP Right Cessation
- 1990-02-16 DE DE9090200348T patent/DE69000743T2/de not_active Expired - Fee Related
- 1990-02-16 ES ES199090200348T patent/ES2046671T3/es not_active Expired - Lifetime
- 1990-02-16 EP EP90200348A patent/EP0384522B1/en not_active Expired - Lifetime
- 1990-02-16 DK DK90200348.2T patent/DK0384522T3/da active
- 1990-02-19 MA MA22010A patent/MA21748A1/fr unknown
- 1990-02-20 YU YU33490A patent/YU47219B/sh unknown
- 1990-02-20 JO JO19901610A patent/JO1610B1/en active
- 1990-02-21 EG EG11190A patent/EG19674A/xx active
- 1990-02-21 AP APAP/P/1990/000166A patent/AP139A/en active
- 1990-02-22 PT PT93227A patent/PT93227B/pt not_active IP Right Cessation
- 1990-02-22 JP JP2039883A patent/JP2588624B2/ja not_active Expired - Fee Related
- 1990-02-22 NO NO900848A patent/NO173503C/no unknown
- 1990-02-22 IE IE65090A patent/IE63155B1/en not_active IP Right Cessation
- 1990-02-22 TN TNTNSN90021A patent/TNSN90021A1/fr unknown
- 1990-02-22 CA CA002010639A patent/CA2010639C/en not_active Expired - Fee Related
- 1990-02-22 AU AU50038/90A patent/AU617926B2/en not_active Ceased
- 1990-02-22 FI FI900897A patent/FI92830C/fi not_active IP Right Cessation
- 1990-02-22 HU HU90896A patent/HU204831B/hu not_active IP Right Cessation
- 1990-02-23 PH PH40105A patent/PH27113A/en unknown
- 1990-02-23 OA OA59740A patent/OA09196A/xx unknown
1993
- 1993-01-21 GR GR930400107T patent/GR3006855T3/el unknown
1995
- 1995-06-28 HU HU95P/P00504P patent/HU211250A9/hu unknown
- 1995-07-13 HK HK114995A patent/HK114995A/xx not_active IP Right Cessation
1996
- 1996-04-05 CY CY186896A patent/CY1868A/xx unknown
- 1996-06-18 LV LV960193A patent/LV5782B4/xx unknown

Also Published As

Publication number	Publication date
NO900848D0 (no)	1990-02-22
IL93136A (en)	1995-01-24
FI92830C (fi)	1995-01-10
CA2010639C (en)	2001-04-17
IE900650L (en)	1990-08-23
ES2046671T3 (es)	1994-02-01
EP0384522B1 (en)	1993-01-13
OA09196A (en)	1992-06-30
CA2010639A1 (en)	1990-08-23
FI900897A0 (fi)	1990-02-22
HU900896D0 (en)	1990-05-28
NZ232548A (en)	1991-03-26
AP9000166A0 (en)	1990-04-30
PT93227B (pt)	1996-01-31
IE63155B1 (en)	1995-03-22
GR3006855T3 (sh)	1993-06-30
YU47219B (sh)	1995-01-31
EP0384522A1 (en)	1990-08-29
YU33490A (sh)	1992-09-07
MY106231A (en)	1995-04-29
DK0384522T3 (da)	1993-04-19
IL93136A0 (en)	1990-11-05
PH27113A (en)	1993-03-16
DE69000743T2 (de)	1993-05-13
HUT54158A (en)	1991-01-28
MA21748A1 (fr)	1990-10-01
FI92830B (fi)	1994-09-30
ATE84534T1 (de)	1993-01-15
HK114995A (en)	1995-07-21
PT93227A (pt)	1990-08-31
AU5003890A (en)	1990-08-30
JPH02270876A (ja)	1990-11-05
HU211250A9 (en)	1995-11-28
NO173503C (no)	1993-12-22
NO173503B (no)	1993-09-13
AU617926B2 (en)	1991-12-05
AP139A (en)	1991-10-15
TNSN90021A1 (fr)	1991-03-05
JO1610B1 (en)	1990-07-01
DE69000743D1 (de)	1993-02-25
LV5782A4 (lv)	1996-12-20
NO900848L (no)	1990-08-24
CY1868A (en)	1996-04-05
HU204831B (en)	1992-02-28
LV5782B4 (lv)	1997-06-20
JP2588624B2 (ja)	1997-03-05

Publication	Publication Date	Title
AP9000163A0 (en)	1990-04-30	Substituted:1,3 oxathiolanes with antiviral properties
EG19674A (en)	1996-06-30	Antiviral tetrahydroimidazol (1,4) denzodiazepin -2-thiones
EP0391187A3 (en)	1990-11-14	Substituted 4-amino-5-alkylthio-1,2,4-triazol-3-ones
IL94148A0 (en)	1991-01-31	N-sulfenyl-and n-sulfinyl-n,n'-diacylhydrazides
GB8911158D0 (en)	1989-07-05	Antiviral pyridazinamines
AP9000205A0 (en)	1990-10-31	Antiviral tetrahydroimidazo(1,4)benzodia-zepines
ZA90301B (en)	1991-03-27	8,9-annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
ZA895454B (en)	1990-04-25	2,2-dihalogenocy-clopropyl-hydroxy-ethyltriazoles
ZA901366B (en)	1991-10-30	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
GB8920354D0 (en)	1989-10-25	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
GB8904962D0 (en)	1989-04-12	Antiviral uses
ZA891059B (en)	1989-10-25	1-aminomethyl-3-(2,4-difluoro-3-chlorophenyl)-4-cyano-pyrroles
GB8922397D0 (en)	1989-11-22	Antiviral pentofuranosides
IE891279L (en)	1989-10-21	3,4-dihydroxy-2-pyrrolidinones
CS491889A1 (en)	1990-08-14	1,2,3,6-tetra-0-acetyl-4-0-(2,3,4-tri-0-acetyl-beta-d-xylopyranozyl)-beta-d-glucopyranose
CS382889A1 (en)	1990-12-13	8,10-disubstituted 6,8-dimethylergolines
IE891569L (en)	1989-11-16	2, 6-diaminopyridines
CS634386A1 (en)	1987-07-16	X 2 (2 benzotiazolyl) 1,3 indandiony
IE890468L (en)	1989-08-16	2', 3' - dideoxy-2',2'-difluoronucleosides
CS8900223A1 (en)	1990-10-12	1,6-dioxa-9,9,10,11,11-pentamethyl-10-azaspiro (6,5) dodec-3-ene
CS632786A1 (en)	1987-06-11	N (2,6 dichlorfenyl) benziminofenylether
CS632886A1 (en)	1988-06-15	N (2,6 dichlorfenyl) benzimidoylchlorid
CS857186A1 (en)	1987-09-17	Zpusob pripravy 1 tricyklo (3,3,1,13,7) dekankarboxylove kyseliny
GB8906474D0 (en)	1989-05-04	Antiviral compounds
GB8903927D0 (en)	1989-04-05	Antiviral compounds