EE9900075A - 7α- (-aminoalkyl) oestratrienes, process for their preparation, pharmaceutical preparations containing 7α- (-aminoalkyl) oestratrienes and their use in the manufacture of medicaments - Google Patents

7α- (-aminoalkyl) oestratrienes, process for their preparation, pharmaceutical preparations containing 7α- (-aminoalkyl) oestratrienes and their use in the manufacture of medicaments

Info

Publication number: EE9900075A
Authority: EE; Estonia
Prior art keywords: oestratrienes; aminoalkyl; medicaments; manufacture; preparation
Prior art date: 1996-08-20

Application number

EEP199900075A

Other languages

Estonian (et)

Other versions

EE04021B1 (en

Inventor

Bohlmann Rolf

Bittler Dieter

Heindl Josef

Heinrich Nikolaus

Hofmeister Helmut

K�nzer Hermann

Sauer Gerhard

Hegele-Hartung Christa

Lichtner Rosemarie

Nishino Yukishige

Parczyk Karsten

Schneider Martin

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-20

Filing date

1997-08-20

Publication date

1999-10-15

1997-08-20 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

1999-10-15 Publication of EE9900075A publication Critical patent/EE9900075A/en

2003-04-15 Publication of EE04021B1 publication Critical patent/EE04021B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EEP199900075A 1996-08-20 1997-08-20 7α- (-aminoalkyl) oestratrienes, process for their preparation, pharmaceutical preparations containing 7α- (-aminoalkyl) oestratrienes and their use in the manufacture of medicaments EE04021B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19635525A DE19635525A1 (en)	1996-08-20	1996-08-20	New 7-alpha-(xi-aminoalkyl)- oestratriene derivatives
PCT/EP1997/004517 WO1998007740A1 (en)	1996-08-20	1997-08-20	7α-(κ-AMINOALKYL)ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7α-(κ-AMINOALKYL)ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS

Publications (2)

Publication Number	Publication Date
EE9900075A true EE9900075A (en)	1999-10-15
EE04021B1 EE04021B1 (en)	2003-04-15

Family

ID=7804367

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900075A EE04021B1 (en)	1996-08-20	1997-08-20	7α- (-aminoalkyl) oestratrienes, process for their preparation, pharmaceutical preparations containing 7α- (-aminoalkyl) oestratrienes and their use in the manufacture of medicaments

Country Status (29)

Country	Link
EP (1)	EP0920441B1 (en)
JP (1)	JP2001503024A (en)
KR (1)	KR20000068261A (en)
CN (1)	CN1231670A (en)
AR (1)	AR009278A1 (en)
AT (1)	ATE231882T1 (en)
AU (1)	AU728843B2 (en)
BG (1)	BG62972B1 (en)
BR (1)	BR9711328A (en)
CA (1)	CA2263708A1 (en)
CZ (1)	CZ57999A3 (en)
DE (2)	DE19635525A1 (en)
DK (1)	DK0920441T3 (en)
EA (1)	EA001577B1 (en)
EE (1)	EE04021B1 (en)
ES (1)	ES2191857T3 (en)
HU (1)	HUP9903106A3 (en)
IL (1)	IL128601A (en)
IS (1)	IS4976A (en)
NO (1)	NO315655B1 (en)
NZ (1)	NZ334277A (en)
PL (1)	PL186309B1 (en)
PT (1)	PT920441E (en)
SK (1)	SK18899A3 (en)
TR (1)	TR199900432T2 (en)
TW (1)	TW552267B (en)
UA (1)	UA50792C2 (en)
WO (1)	WO1998007740A1 (en)
ZA (1)	ZA977482B (en)

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AR015500A1 (en) *	1997-12-23	2001-05-02	Schering Ag	11 BETA-HALOGEN-STRATRIENS REPLACED IN 7 ALPHA, PROCEDURE FOR PREPARING PHARMACEUTICAL PREPARATIONS THAT CONTAIN SUCH 11 BETA-HALOGEN-STRATRIENS REPLACED IN 7 ALPHA, AS WELL AS USED IN THE PREPARATION OF MEDICINES.
US6054446A (en) *	1997-12-24	2000-04-25	Sri International	Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6548491B2 (en)	1997-12-24	2003-04-15	Sri International	Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6503896B1 (en)	1997-12-24	2003-01-07	Sri International	Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
DE19807791A1 (en) *	1998-02-19	1999-08-26	Schering Ag	Combination preparation of estrogen with 7-aminoalkyl-estratriene antiestrogen, useful in hormone replacement therapy, e.g. for treatment osteoporosis, Alzheimer's disease and hot flushes
DE19833786A1 (en) *	1998-07-18	2000-01-20	Schering Ag	New diphenyl-benzocycloheptene derivatives, are tissue-selective estrogens and antiestrogens useful e.g. for treating osteoporosis or hormone-dependent tumors or in hormone replacement therapy
DE19842123C1 (en) *	1998-09-05	2000-07-13	Schering Ag	11beta-fluoro-7alpha- (14,14,15,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl) estra-1,3,5 (10) - triene-3,17beta-diol as crystalline solvate
DE19906159A1 (en) *	1999-02-09	2000-08-10	Schering Ag	16-hydroxyestratrienes as selectively active estrogens
AU6913700A (en) *	1999-08-18	2001-03-13	Schering Aktiengesellschaft	Piperidine and pyrrolidine derivatives displaying neuronal activity
GB0000313D0 (en) *	2000-01-10	2000-03-01	Astrazeneca Uk Ltd	Formulation
DE10019171A1 (en) *	2000-04-07	2001-10-18	Schering Ag	Compositions for use as penetration enhancers in transdermal formulations for highly lipophilic active ingredients
AU2006202187B2 (en) *	2001-11-27	2008-11-06	Bayer Schering Pharma Aktiengesellschaft	17alpah-alkyl-17beta-oxy-estratrienes and intermediate products for their production, uses thereof and pharmaceutical preparations
DE10159217A1 (en) *	2001-11-27	2003-06-05	Schering Ag	17alpha-alkyl-17ß-oxy-estratrienes and intermediates for their preparation, use of 17alpha-alkyl-17ß-oxy-estratriene for the preparation of medicaments and pharmaceutical preparations
US20040242551A1 (en) *	2003-05-28	2004-12-02	Schering Ag	Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
EP1771462B1 (en) *	2004-07-27	2010-09-29	Sicor Inc.	A process for the preparation of 7-alpha-alkylated 19-norsteroids
CN101312944B (en)	2005-11-22	2013-03-06	住友化学株式会社	Organic sulfur compounds and use thereof as arthropodicides
DE102007023614A1 (en)	2007-05-21	2008-11-27	Bayer Schering Pharma Aktiengesellschaft	New amide compounds used for treatment of gynecological diseases e.g. endometriosis, for female fertility control and female hormone replacement therapy, has general formula
DE102007049630A1 (en)	2007-10-11	2009-10-29	Bayer Schering Pharma Aktiengesellschaft	New amide compounds used for therapy and/or prophylaxis of gynecological diseases e.g. endometriosis, for female fertility control and female hormone replacement therapy
TW200904329A (en)	2007-05-18	2009-02-01	Sumitomo Chemical Co	Organic sulfur compound and its use for controlling harmful arthropod
JP2009001551A (en)	2007-05-18	2009-01-08	Sumitomo Chemical Co Ltd	Organic sulfur compounds and their use for controlling harmful arthropods
JP5298631B2 (en)	2007-05-18	2013-09-25	住友化学株式会社	Organic sulfur compounds and their use for controlling harmful arthropods
DE102007032800A1 (en)	2007-07-10	2009-01-15	Bayer Schering Pharma Aktiengesellschaft	Nonsteroidal progesterone receptor modulators
EA022760B1 (en)	2007-10-16	2016-02-29	Репрос Терапьютикс Инк.	Use of trans-clomiphene for prevention or treatment of type 2 diabetes in men
DE102007058747A1 (en)	2007-12-05	2009-06-10	Bayer Schering Pharma Aktiengesellschaft	Nonsteroidal progesterone receptor modulators
EP2070941A1 (en)	2007-12-14	2009-06-17	Bayer Schering Pharma Aktiengesellschaft	Stereoselective synthesis of selective estrogen receptor down-regulators
EP2070909A1 (en)	2007-12-15	2009-06-17	Bayer Schering Pharma AG	Non-steroidal progesterone receptor modulators
DE102008057230A1 (en)	2008-11-11	2010-05-12	Bayer Schering Pharma Aktiengesellschaft	Synergistic pharmaceutical combination with an estrogen receptor antagonist and a progestin
JP5212350B2 (en) *	2008-12-24	2013-06-19	住友化学株式会社	Halogen-containing organic sulfur compounds and uses thereof
EP2258375A1 (en)	2009-06-04	2010-12-08	Bayer Schering Pharma Aktiengesellschaft	17B-alkyl-17alpha-oxy-estratrienes
DE102009034367A1 (en)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-benzylidene derivatives, process for their preparation and their use for the treatment of diseases
DE102009034366A1 (en)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-methyleneoxyalkylene aryl derivatives, process for their preparation and their use for the treatment of diseases
DE102009034362A1 (en)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-aryl derivatives, process for their preparation and their use for the treatment of diseases
DE102009034368A1 (en)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-acyloxyalkylenephenyl derivatives, process for their preparation and their use for the treatment of diseases
DE102009034525A1 (en)	2009-07-21	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-aryl derivatives, process for their preparation and their use for the treatment of diseases
DE102009034526A1 (en)	2009-07-21	2011-02-10	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluoroethyl-estra-4,9 (10) -diene-11-ethynylphenyl derivatives, process for their preparation and their use for the treatment of diseases
WO2011092127A1 (en)	2010-01-26	2011-08-04	Bayer Schering Pharma Aktiengesellschaft	14,17-bridged estratriene derivatives comprising heterocyclic bioisosteres for the phenolic a-ring
DE102010007722A1 (en)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesterone receptor antagonist
DE102010007719A1 (en)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesterone receptor antagonist
US11576891B2 (en)	2010-06-16	2023-02-14	Endorecherche, Inc.	Methods of treating or preventing estrogen-related diseases
DE102010030538A1 (en)	2010-06-25	2011-12-29	Bayer Schering Pharma Aktiengesellschaft	6,7-Dihydro-5H-benzo [7] annulene derivatives, process for their preparation, pharmaceutical preparations containing them and their use for the preparation of medicaments
DE102011004899A1 (en)	2011-03-01	2012-09-06	Bayer Pharma Aktiengesellschaft	New 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl-derivatives are progesterone receptor antagonists useful to treat and prevent e.g. uterine fibroids, endometriosis, heavy menstrual bleeding and meningioma
HUE062616T2 (en)	2011-09-08	2023-11-28	Sage Therapeutics Inc	Neuroactive steroids, preparations and their applications
DE102011087987A1 (en)	2011-12-08	2013-06-13	Bayer Intellectual Property Gmbh	6,7-Dihydro-5H-benzo [7] annulene derivatives, process for their preparation, pharmaceutical preparations containing them and their use for the preparation of medicaments
AU2013225869B2 (en)	2012-02-29	2017-06-08	Repros Therapeutics Inc.	Combination therapy for treating androgen deficiency
JP6255082B2 (en)	2013-03-13	2017-12-27	セージセラピューティクス，インコーポレイテッド	Nerve stimulating steroids and methods of use thereof
DK2983671T3 (en)	2013-04-11	2019-02-18	Bayer Pharma AG	DOSAGE FORM FOR PROGESTERON RECEPTOR ANAGONIST
US20160060288A1 (en) *	2013-04-18	2016-03-03	Xi'anlibang Pharmaceutical Technology Co., Ltd.	Ester derivatives of 7-alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-estra-1,3,5(10)-triene-3,17beta-diol having anticancer activity and preparation method thereof
JP6628745B2 (en)	2014-06-18	2020-01-15	セージセラピューティクス，インコーポレイテッド	Oxysterols and methods of using same
JP7048505B2 (en)	2015-11-10	2022-04-05	パラクリンセラピューティクスエービー	Treatment of ER-negative breast cancer with PDGF-CC inhibitors and antiestrogens
CN114272249A (en)	2016-04-01	2022-04-05	萨奇治疗股份有限公司	Oxysterol and methods of use thereof
US10752653B2 (en)	2016-05-06	2020-08-25	Sage Therapeutics, Inc.	Oxysterols and methods of use thereof
DK3481846T3 (en)	2016-07-07	2021-08-16	Sage Therapeutics Inc	11-SUBSTITUTED 24-HYDROXYSTEROLS FOR USE IN THE TREATMENT OF NMDA-RELATED CONDITIONS
NZ752193A (en)	2016-09-30	2024-11-29	Sage Therapeutics Inc	C7 substituted oxysterols and methods as nmda modulators
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1996
- 1996-08-20 DE DE19635525A patent/DE19635525A1/en not_active Withdrawn
1997
- 1997-08-20 TW TW086111927A patent/TW552267B/en active
- 1997-08-20 IL IL12860197A patent/IL128601A/en not_active IP Right Cessation
- 1997-08-20 CN CN97198245A patent/CN1231670A/en active Pending
- 1997-08-20 EA EA199900210A patent/EA001577B1/en not_active IP Right Cessation
- 1997-08-20 EE EEP199900075A patent/EE04021B1/en not_active IP Right Cessation
- 1997-08-20 AT AT97943814T patent/ATE231882T1/en not_active IP Right Cessation
- 1997-08-20 ES ES97943814T patent/ES2191857T3/en not_active Expired - Lifetime
- 1997-08-20 DK DK97943814T patent/DK0920441T3/en active
- 1997-08-20 PL PL97331863A patent/PL186309B1/en not_active IP Right Cessation
- 1997-08-20 AR ARP970103779A patent/AR009278A1/en not_active Application Discontinuation
- 1997-08-20 PT PT97943814T patent/PT920441E/en unknown
- 1997-08-20 KR KR1019997001396A patent/KR20000068261A/en not_active Application Discontinuation
- 1997-08-20 BR BR9711328A patent/BR9711328A/en unknown
- 1997-08-20 TR TR1999/00432T patent/TR199900432T2/en unknown
- 1997-08-20 CA CA002263708A patent/CA2263708A1/en not_active Abandoned
- 1997-08-20 JP JP10510412A patent/JP2001503024A/en not_active Ceased
- 1997-08-20 HU HU9903106A patent/HUP9903106A3/en unknown
- 1997-08-20 NZ NZ334277A patent/NZ334277A/en unknown
- 1997-08-20 SK SK188-99A patent/SK18899A3/en unknown
- 1997-08-20 UA UA99031552A patent/UA50792C2/en unknown
- 1997-08-20 AU AU45520/97A patent/AU728843B2/en not_active Ceased
- 1997-08-20 EP EP97943814A patent/EP0920441B1/en not_active Expired - Lifetime
- 1997-08-20 ZA ZA9707482A patent/ZA977482B/en unknown
- 1997-08-20 DE DE59709239T patent/DE59709239D1/en not_active Expired - Fee Related
- 1997-08-20 CZ CZ99579A patent/CZ57999A3/en unknown
- 1997-08-20 WO PCT/EP1997/004517 patent/WO1998007740A1/en not_active Application Discontinuation
1999
- 1999-02-11 IS IS4976A patent/IS4976A/en unknown
- 1999-02-16 BG BG103185A patent/BG62972B1/en unknown
- 1999-02-19 NO NO19990793A patent/NO315655B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IS4976A (en)	1999-02-11
AU728843B2 (en)	2001-01-18
HUP9903106A3 (en)	2000-05-29
EA199900210A1 (en)	1999-08-26
ATE231882T1 (en)	2003-02-15
ES2191857T3 (en)	2003-09-16
NO315655B1 (en)	2003-10-06
NO990793L (en)	1999-04-20
EP0920441B1 (en)	2003-01-29
EE04021B1 (en)	2003-04-15
SK18899A3 (en)	1999-08-06
AR009278A1 (en)	2000-04-12
HUP9903106A2 (en)	2000-03-28
JP2001503024A (en)	2001-03-06
IL128601A (en)	2003-07-31
KR20000068261A (en)	2000-11-25
PL186309B1 (en)	2003-12-31
UA50792C2 (en)	2002-11-15
EA001577B1 (en)	2001-06-25
WO1998007740A1 (en)	1998-02-26
PL331863A1 (en)	1999-08-16
NO990793D0 (en)	1999-02-19
DE19635525A1 (en)	1998-02-26
PT920441E (en)	2003-06-30
CA2263708A1 (en)	1998-02-26
CZ57999A3 (en)	1999-08-11
EP0920441A1 (en)	1999-06-09
BR9711328A (en)	1999-08-17
TW552267B (en)	2003-09-11
BG62972B1 (en)	2000-12-29
AU4552097A (en)	1998-03-06
DK0920441T3 (en)	2003-05-26
IL128601A0 (en)	2000-01-31
NZ334277A (en)	2000-10-27
DE59709239D1 (en)	2003-03-06
BG103185A (en)	1999-11-30
CN1231670A (en)	1999-10-13
TR199900432T2 (en)	1999-04-21
ZA977482B (en)	1998-02-23

Publication	Publication Date	Title
EE9900075A (en)	1999-10-15	7α- (-aminoalkyl) oestratrienes, process for their preparation, pharmaceutical preparations containing 7α- (-aminoalkyl) oestratrienes and their use in the manufacture of medicaments
EE9700145A (en)	1998-02-16	Cycloalkanepyridines, their method of preparation, their use in the manufacture of medicinal products and medicinal products containing these compounds
EE9700153A (en)	1998-02-16	Heterocycle-fused pyridines, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
EE04273B1 (en)	2004-04-15	Benzocycloheptenes, process for their preparation, pharmaceutical preparations containing them and their use in the manufacture of medicaments
EE9700060A (en)	1997-10-15	2-Aryl-substituted pyridines, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
EE9700019A (en)	1997-08-15	2-Oxo- and 2-thio-1,2-dihydroquinolinyloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
EE200000380A (en)	2001-12-17	11β-halogeno-7 (alpha) substituted estratrienes, processes for the preparation of pharmaceutical preparations containing these 11β-halo-7 (alpha) substituted estratrienes, and their use in the manufacture of medicaments
EE9700020A (en)	1997-08-15	Heteroatom-containing cyclopentanepyridyloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
EE9700031A (en)	1997-08-15	Pyrido-linked thienyl and furanyloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds
EE9700044A (en)	1997-08-15	Heteroaryloxazolidinones, process for their preparation, use in the manufacture of medicaments and medicaments containing these compounds.
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Date	Code	Title	Description
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2005-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20040820