EE9800451A - Novel imidazotriazolopyrimidines, their preparation and their use as therapeutic substances - Google Patents

Novel imidazotriazolopyrimidines, their preparation and their use as therapeutic substances

Info

Publication number: EE9800451A
Authority: EE; Estonia
Prior art keywords: imidazotriazolopyrimidines; novel; preparation; therapeutic substances; therapeutic
Prior art date: 1996-07-20

Application number

EE9800451A

Other languages

Estonian (et)

Inventor

K�fner-M�hl Ulrike

Kummer Werner

Pohl Gerald

Gaida Wolfram

Lehr Erich

Mierau Joachim

Weiser Thomas

Original Assignee

Boehringer Ingelheim Pharma Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-20

Filing date

1997-07-17

Publication date

1999-06-15

1997-07-17 Application filed by Boehringer Ingelheim Pharma Kg filed Critical Boehringer Ingelheim Pharma Kg

1998-06-26 Priority claimed from CA002242097A external-priority patent/CA2242097C/en

1999-06-15 Publication of EE9800451A publication Critical patent/EE9800451A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EE9800451A 1996-07-20 1997-07-17 Novel imidazotriazolopyrimidines, their preparation and their use as therapeutic substances EE9800451A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19629378A DE19629378A1 (en)	1996-07-20	1996-07-20	New triazolopurines, process for their preparation and their use as medicaments
PCT/EP1997/003841 WO1998003511A1 (en)	1996-07-20	1997-07-17	New triazolopurines, method of preparing them and their use as drugs
CA002242097A CA2242097C (en)	1996-07-20	1998-06-26	Imidazotriazolopyrimidines, process for preparing them and their use as pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
EE9800451A true EE9800451A (en)	1999-06-15

Family

ID=32963000

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800451A EE9800451A (en)	1996-07-20	1997-07-17	Novel imidazotriazolopyrimidines, their preparation and their use as therapeutic substances

Country Status (25)

Country	Link
EP (2)	EP0880524B1 (en)
JP (1)	JP3020281B2 (en)
CN (1)	CN1219936A (en)
AT (1)	ATE191913T1 (en)
AU (1)	AU3695597A (en)
BG (1)	BG102707A (en)
BR (1)	BR9710747A (en)
CA (1)	CA2256736A1 (en)
CZ (1)	CZ265498A3 (en)
DE (2)	DE19629378A1 (en)
DK (1)	DK0880524T3 (en)
EE (1)	EE9800451A (en)
ES (1)	ES2147453T3 (en)
GR (1)	GR3033842T3 (en)
HR (1)	HRP970395A2 (en)
HU (1)	HUP9902311A3 (en)
ID (1)	ID19106A (en)
IL (1)	IL126453A0 (en)
NO (1)	NO983860L (en)
PL (1)	PL328824A1 (en)
PT (1)	PT880524E (en)
SK (1)	SK114498A3 (en)
TR (1)	TR199801659T2 (en)
WO (1)	WO1998003511A1 (en)
ZA (1)	ZA976331B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19826843A1 (en) *	1998-06-16	1999-12-23	Boehringer Ingelheim Pharma	Novel imidazotriazolopyrimidines, process for their preparation and their use as medicaments
US6492377B1 (en)	1998-06-25	2002-12-10	Boehringer Ingelheim Pharma Kg	Imidazotriazolopyrimidines with adenosine-antagonistic activity
WO2000012511A1 (en) *	1998-08-27	2000-03-09	Boehringer Ingelheim Pharma Kg	Imidazotriazolopyrimidines
US7329668B2 (en)	2003-02-25	2008-02-12	Bristol-Myers Squibb Company	Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
US7071333B2 (en)	2003-07-30	2006-07-04	Bristol-Myers Squibb Company	Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
BRPI0713619A2 (en)	2006-06-23	2013-01-15	Incyte Corp	compound or prodrug or pharmaceutically acceptable salt thereof, composition, and use of the compound.
MX2020008949A (en)	2018-02-27	2021-01-08	Incyte Corp	Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors.
JP7391046B2 (en)	2018-05-18	2023-12-04	インサイト・コーポレイション	Fused pyrimidine derivatives as A2A/A2B inhibitors
IL279829B2 (en)	2018-07-05	2025-05-01	Incyte Holdings Corp	Fused pyrazine derivatives as a2a / a2b inhibitors
JOP20210116A1 (en)	2018-11-30	2023-01-30	Merck Sharp & Dohme	9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use
TWI829857B (en)	2019-01-29	2024-01-21	美商英塞特公司	Pyrazolopyridines and triazolopyridines as a2a / a2b inhibitors
CN112778311B (en) *	2019-11-01	2024-06-04	上海翰森生物医药科技有限公司	Nitrogen-containing cyclic derivative inhibitor, preparation method and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA902282B (en) *	1989-03-29	1990-12-28	Merrell Dow Pharma	Selective adenosine receptor compounds
IT1264901B1 (en) *	1993-06-29	1996-10-17	Schering Plough S P A	HETEROCYCLIC ANALOGUES OF 1,2,4-TRIAZOLE(15-C)PYRIMIDINES WITH ANTAGONIST ACTIVITY FOR THE ADENOSINE A2 RECEPTOR
JPH083169A (en) *	1994-06-15	1996-01-09	Yamasa Shoyu Co Ltd	4-Methyl-1H- [1,2,4] triazolo [1,5-a] purin-9 (4H) -ones

1996
- 1996-07-20 DE DE19629378A patent/DE19629378A1/en not_active Withdrawn
1997
- 1997-07-17 DK DK97933683T patent/DK0880524T3/en active
- 1997-07-17 BR BR9710747A patent/BR9710747A/en unknown
- 1997-07-17 EP EP97933683A patent/EP0880524B1/en not_active Expired - Lifetime
- 1997-07-17 EE EE9800451A patent/EE9800451A/en unknown
- 1997-07-17 SK SK1144-98A patent/SK114498A3/en unknown
- 1997-07-17 AU AU36955/97A patent/AU3695597A/en not_active Abandoned
- 1997-07-17 IL IL12645397A patent/IL126453A0/en unknown
- 1997-07-17 PT PT97933683T patent/PT880524E/en unknown
- 1997-07-17 ES ES97933683T patent/ES2147453T3/en not_active Expired - Lifetime
- 1997-07-17 CA CA002256736A patent/CA2256736A1/en not_active Abandoned
- 1997-07-17 WO PCT/EP1997/003841 patent/WO1998003511A1/en not_active Ceased
- 1997-07-17 ZA ZA976331A patent/ZA976331B/en unknown
- 1997-07-17 HU HU9902311A patent/HUP9902311A3/en unknown
- 1997-07-17 DE DE59701467T patent/DE59701467D1/en not_active Expired - Lifetime
- 1997-07-17 TR TR1998/01659T patent/TR199801659T2/en unknown
- 1997-07-17 AT AT97933683T patent/ATE191913T1/en active
- 1997-07-17 CZ CZ982654A patent/CZ265498A3/en unknown
- 1997-07-17 CN CN97194506A patent/CN1219936A/en active Pending
- 1997-07-17 EP EP99119410A patent/EP0978517A3/en not_active Withdrawn
- 1997-07-17 PL PL97328824A patent/PL328824A1/en unknown
- 1997-07-17 JP JP10505626A patent/JP3020281B2/en not_active Expired - Fee Related
- 1997-07-18 HR HR19629378.2A patent/HRP970395A2/en not_active Application Discontinuation
- 1997-07-18 ID IDP972495A patent/ID19106A/en unknown
1998
- 1998-08-20 BG BG102707A patent/BG102707A/en unknown
- 1998-08-21 NO NO983860A patent/NO983860L/en not_active Application Discontinuation
2000
- 2000-06-30 GR GR20000401543T patent/GR3033842T3/en unknown

Also Published As

Publication number	Publication date
EP0978517A3 (en)	2003-11-12
JP2000501420A (en)	2000-02-08
ZA976331B (en)	1999-01-25
DK0880524T3 (en)	2000-07-17
EP0880524A1 (en)	1998-12-02
ID19106A (en)	1998-06-18
SK114498A3 (en)	1999-02-11
BG102707A (en)	1999-09-30
IL126453A0 (en)	1999-08-17
CZ265498A3 (en)	1998-12-16
DE59701467D1 (en)	2000-05-25
DE19629378A1 (en)	1998-01-29
GR3033842T3 (en)	2000-10-31
CN1219936A (en)	1999-06-16
PT880524E (en)	2000-07-31
NO983860L (en)	1998-10-21
EP0880524B1 (en)	2000-04-19
NO983860D0 (en)	1998-08-21
ES2147453T3 (en)	2000-09-01
PL328824A1 (en)	1999-02-15
ATE191913T1 (en)	2000-05-15
BR9710747A (en)	1999-08-17
HUP9902311A3 (en)	2000-06-28
TR199801659T2 (en)	1998-12-21
CA2256736A1 (en)	1998-01-29
HRP970395A2 (en)	1998-08-31
AU3695597A (en)	1998-02-10
EP0978517A2 (en)	2000-02-09
JP3020281B2 (en)	2000-03-15
HUP9902311A2 (en)	1999-10-28
WO1998003511A1 (en)	1998-01-29

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