EE200200087A - Kompositsioon hepatotsellulaarse kartsinoomi raviks - Google Patents

Kompositsioon hepatotsellulaarse kartsinoomi raviks

Info

Publication number: EE200200087A
Authority: EE; Estonia
Prior art keywords: hepatocellular carcinoma; treatment; composition; docetaxel; mum
Prior art date: 1999-08-31

Application number

EEP200200087A

Other languages

English (en)

Inventor

Chi Chin-Wen

Lin Heng-Liang

Liu Tsung-Yun

Lui Wing-Yiu

Chau Gar-Yang

Original Assignee

Aventis Pharma S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-31

Filing date

2000-08-29

Publication date

2003-04-15

2000-08-29 Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.

2003-04-15 Publication of EE200200087A publication Critical patent/EE200200087A/et

2009-02-16 Publication of EE05124B1 publication Critical patent/EE05124B1/et

Links

206010073071 hepatocellular carcinoma Diseases 0.000 title abstract 3
231100000844 hepatocellular carcinoma Toxicity 0.000 title abstract 3
ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 2
229960003668 docetaxel Drugs 0.000 abstract 2
229930012538 Paclitaxel Natural products 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

EEP200200087A 1999-08-31 2000-08-29 Toimeainena dotsetakseeli v?i selle hdraati sisaldava kompositsiooni kasutamine EE05124B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9920548.6A GB9920548D0 (en)	1999-08-31	1999-08-31	Treatment of hepatocellular carcinoma
PCT/EP2000/008782 WO2001015675A2 (en)	1999-08-31	2000-08-29	Use of docetaxel for treating hepatocellular carcinoma

Publications (2)

Publication Number	Publication Date
EE200200087A true EE200200087A (et)	2003-04-15
EE05124B1 EE05124B1 (et)	2009-02-16

Family

ID=10860081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200087A EE05124B1 (et)	1999-08-31	2000-08-29	Toimeainena dotsetakseeli v?i selle hdraati sisaldava kompositsiooni kasutamine

Country Status (34)

Country	Link
US (2)	US20030158249A1 (et)
EP (1)	EP1214061B1 (et)
JP (1)	JP4866522B2 (et)
KR (1)	KR100670416B1 (et)
CN (1)	CN1174748C (et)
AT (1)	ATE269700T1 (et)
AU (1)	AU777583B2 (et)
BG (1)	BG65913B1 (et)
BR (1)	BR0013625A (et)
CA (1)	CA2382294C (et)
CZ (1)	CZ301378B6 (et)
DE (1)	DE60011794T2 (et)
DK (1)	DK1214061T3 (et)
EA (1)	EA004804B1 (et)
EE (1)	EE05124B1 (et)
ES (1)	ES2218223T3 (et)
GB (1)	GB9920548D0 (et)
HK (1)	HK1048944B (et)
HR (1)	HRP20020171A2 (et)
HU (1)	HU228861B1 (et)
IL (2)	IL147489A0 (et)
ME (1)	MEP7809A (et)
MX (1)	MXPA02002041A (et)
NO (1)	NO328527B1 (et)
NZ (1)	NZ517604A (et)
PL (1)	PL212612B1 (et)
PT (1)	PT1214061E (et)
RS (1)	RS50148B (et)
SI (1)	SI1214061T1 (et)
SK (1)	SK286378B6 (et)
TW (1)	TW589180B (et)
UA (1)	UA72927C2 (et)
WO (1)	WO2001015675A2 (et)
ZA (1)	ZA200201408B (et)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1268619C (zh)	2003-05-08	2006-08-09	上海迪赛诺化学制药有限公司	多烯紫杉醇三水化合物的制备方法
EP1694660B1 (en) *	2003-12-12	2009-04-08	Quiral Quimica Do Brasil	Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions
US7449196B2 (en) *	2004-07-09	2008-11-11	Robert Sabin	Anti tumor compositions and methods of use
JP5368093B2 (ja)	2005-08-31	2013-12-18	アブラクシスバイオサイエンス，エルエルシー	増大した安定性を有する難水溶性薬剤の組成物および調製の方法
SI3311805T1 (sl) *	2005-08-31	2020-07-31	Abraxis Bioscience, Llc	Sestave, ki zajemajo slabo vodotopne farmacevtske učinkovine in antimikrobna sredstva
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
US20080081051A1 (en) *	2006-09-28	2008-04-03	Robert Sabin	Method of manufacturing anti-tumor and anti-viral compositions
CN102014918A (zh) *	2007-04-20	2011-04-13	太阳医药工业有限公司	由微量沉淀产生的药学组合物
FR2917088B1 (fr) *	2007-06-08	2009-09-04	Aventis Pharma Sa	Dissolution directe du docetaxel dans un solvant dans le polysorbate 80
US8541360B2 (en) *	2008-11-19	2013-09-24	Ben Venue Laboratories, Inc.	Parenteral formulations comprising sugar-based esters and ethers
LT2552438T (lt)	2010-03-26	2016-09-26	Abraxis Bioscience, Llc	Hepatoceliulinės karcinomos gydymo būdai
BR112012028037A2 (pt) *	2010-05-03	2016-08-02	Teikoku Pharma Usa Inc	formulação de pró-emulsão líquida de taxano não aquosa, métodos para administrar um taxano a um paciente e para fabricar uma formulação de pró-emulsão de taxano, composição de emulsão de taxano, e, kit
US8842114B1 (en)	2011-04-29	2014-09-23	Nvidia Corporation	System, method, and computer program product for adjusting a depth of displayed objects within a region of a display
JO3685B1 (ar)	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
EP3258913A1 (en) *	2015-02-17	2017-12-27	Mallinckrodt Nuclear Medicine LLC	Modified docetaxel liposome formulations and uses thereof

Family Cites Families (20)

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Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5543154A (en) *	1991-12-27	1996-08-06	Merck & Co., Inc.	Controlled release nifedipine delivery device
DK0680320T3 (da) *	1993-01-19	1999-10-25	Warner Lambert Co	Stabilt oralt CI-981-præparat og fremgangsmåde til fremstilling deraf
US5846945A (en) *	1993-02-16	1998-12-08	Onyx Pharmaceuticals, Inc.	Cytopathic viruses for therapy and prophylaxis of neoplasia
US5436243A (en) *	1993-11-17	1995-07-25	Research Triangle Institute Duke University	Aminoanthraquinone derivatives to combat multidrug resistance
FR2718963B1 (fr) *	1994-04-25	1996-05-24	Rhone Poulenc Rorer Sa	Nouvelle composition pharmaceutique à base de taxoïdes.
FR2722191B1 (fr) *	1994-07-08	1996-08-23	Rhone Poulenc Rorer Sa	Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
US6245805B1 (en) *	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US5968972A (en)	1995-10-26	1999-10-19	Baker Norton Pharmaceuticals, Inc.	Method for increasing the oral bioactivity of pharmaceutical agents
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
AU741439B2 (en) *	1996-12-30	2001-11-29	Battelle Memorial Institute	Formulation and method for treating neoplasms by inhalation
US6503893B2 (en) *	1996-12-30	2003-01-07	Bone Care International, Inc.	Method of treating hyperproliferative diseases using active vitamin D analogues
KR100789008B1 (ko) *	1997-06-27	2007-12-26	아브락시스 바이오사이언스 인크.	신규 약물 제제
DE69811689T2 (de) *	1997-09-18	2003-12-18	Janssen Pharmaceutica N.V., Beerse	Kondensierte imidazolderivate zur erhöhung der oralen bioverfügbarkeit von pharmazeutika
AU1289899A (en) *	1997-10-31	1999-05-24	Arch Development Corporation	Methods and compositions for regulation of 5-alpha reductase activity
UA73092C2 (uk) *	1998-07-17	2005-06-15	Брістол-Майерс Сквібб Компані	Таблетка з ентеросолюбільним покриттям і спосіб її приготування
BR9916518A (pt) *	1998-12-23	2002-01-29	Searle & Co	Método para tratar ou prevenir um distúrbio de neoplasia em um mamìfero em necessidade de tal tratamento ou prevenção, e, combinação compreendendo um inibidor de ciclooxigenase-2 e um ou mais agentes anti-neoplásticos
GB9909925D0 (en) *	1999-04-29	1999-06-30	Pharmacia & Upjohn Spa	Combined preparations comprising anthracycline derivatives
TW200745026A (en) *	2005-12-13	2007-12-16	Teva Pharma	Crystal form of atorvastatin hemi-calcium and processes for preparation thereof

1999
- 1999-08-31 GB GBGB9920548.6A patent/GB9920548D0/en not_active Ceased
- 1999-09-22 TW TW088115041A patent/TW589180B/zh not_active IP Right Cessation
2000
- 2000-08-29 HU HU0203197A patent/HU228861B1/hu not_active IP Right Cessation
- 2000-08-29 NZ NZ517604A patent/NZ517604A/en not_active IP Right Cessation
- 2000-08-29 HR HR20020171A patent/HRP20020171A2/hr not_active Application Discontinuation
- 2000-08-29 ES ES00964144T patent/ES2218223T3/es not_active Expired - Lifetime
- 2000-08-29 RS YUP-114/02A patent/RS50148B/sr unknown
- 2000-08-29 CZ CZ20020739A patent/CZ301378B6/cs not_active IP Right Cessation
- 2000-08-29 PT PT00964144T patent/PT1214061E/pt unknown
- 2000-08-29 EE EEP200200087A patent/EE05124B1/et not_active IP Right Cessation
- 2000-08-29 KR KR1020027002446A patent/KR100670416B1/ko not_active Expired - Fee Related
- 2000-08-29 SI SI200030478T patent/SI1214061T1/xx unknown
- 2000-08-29 DE DE60011794T patent/DE60011794T2/de not_active Expired - Lifetime
- 2000-08-29 PL PL353198A patent/PL212612B1/pl unknown
- 2000-08-29 CA CA002382294A patent/CA2382294C/en not_active Expired - Fee Related
- 2000-08-29 CN CNB008114501A patent/CN1174748C/zh not_active Expired - Fee Related
- 2000-08-29 EA EA200200313A patent/EA004804B1/ru not_active IP Right Cessation
- 2000-08-29 DK DK00964144T patent/DK1214061T3/da active
- 2000-08-29 IL IL14748900A patent/IL147489A0/xx active IP Right Grant
- 2000-08-29 SK SK271-2002A patent/SK286378B6/sk not_active IP Right Cessation
- 2000-08-29 UA UA2002021546A patent/UA72927C2/uk unknown
- 2000-08-29 AU AU75168/00A patent/AU777583B2/en not_active Ceased
- 2000-08-29 AT AT00964144T patent/ATE269700T1/de active
- 2000-08-29 EP EP00964144A patent/EP1214061B1/en not_active Expired - Lifetime
- 2000-08-29 BR BR0013625-5A patent/BR0013625A/pt not_active Application Discontinuation
- 2000-08-29 MX MXPA02002041A patent/MXPA02002041A/es active IP Right Grant
- 2000-08-29 HK HK03101197.6A patent/HK1048944B/zh not_active IP Right Cessation
- 2000-08-29 WO PCT/EP2000/008782 patent/WO2001015675A2/en active IP Right Grant
- 2000-08-29 JP JP2001519889A patent/JP4866522B2/ja not_active Expired - Fee Related
- 2000-08-29 ME MEP-78/09A patent/MEP7809A/xx unknown
2002
- 2002-01-06 IL IL147489A patent/IL147489A/en not_active IP Right Cessation
- 2002-02-19 ZA ZA200201408A patent/ZA200201408B/xx unknown
- 2002-02-20 NO NO20020829A patent/NO328527B1/no not_active IP Right Cessation
- 2002-02-27 US US10/083,565 patent/US20030158249A1/en not_active Abandoned
- 2002-02-28 BG BG106460A patent/BG65913B1/bg unknown
2007
- 2007-06-12 US US11/761,512 patent/US20080045584A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2001015675A3 (en)	2001-09-20
HUP0203197A2 (hu)	2003-01-28
KR20020060166A (ko)	2002-07-16
EA200200313A1 (ru)	2002-08-29
ES2218223T3 (es)	2004-11-16
NZ517604A (en)	2004-04-30
JP4866522B2 (ja)	2012-02-01
US20080045584A1 (en)	2008-02-21
CA2382294C (en)	2008-06-03
SK2712002A3 (en)	2002-07-02
DE60011794T2 (de)	2005-07-14
UA72927C2 (uk)	2005-05-16
BG65913B1 (bg)	2010-05-31
TW589180B (en)	2004-06-01
EA004804B1 (ru)	2004-08-26
YU11402A (sh)	2005-07-19
HU228861B1 (hu)	2013-06-28
GB9920548D0 (en)	1999-11-03
CA2382294A1 (en)	2001-03-08
ME00624B (me)	2011-12-20
DK1214061T3 (da)	2004-11-01
EE05124B1 (et)	2009-02-16
EP1214061B1 (en)	2004-06-23
CN1372466A (zh)	2002-10-02
RS50148B (sr)	2009-05-06
HK1048944B (zh)	2005-04-22
HK1048944A1 (en)	2003-04-25
NO328527B1 (no)	2010-03-08
CN1174748C (zh)	2004-11-10
CZ301378B6 (cs)	2010-02-03
MXPA02002041A (es)	2002-08-20
PL353198A1 (en)	2003-11-03
MEP7809A (en)	2011-12-20
SI1214061T1 (en)	2004-12-31
ATE269700T1 (de)	2004-07-15
AU7516800A (en)	2001-03-26
EP1214061A2 (en)	2002-06-19
BG106460A (bg)	2002-09-30
BR0013625A (pt)	2002-05-14
IL147489A (en)	2006-06-11
AU777583B2 (en)	2004-10-21
SK286378B6 (sk)	2008-08-05
CZ2002739A3 (cs)	2002-06-12
NO20020829L (no)	2002-02-20
US20030158249A1 (en)	2003-08-21
DE60011794D1 (de)	2004-07-29
PT1214061E (pt)	2004-09-30
HUP0203197A3 (en)	2005-01-28
ZA200201408B (en)	2003-07-30
IL147489A0 (en)	2002-08-14
PL212612B1 (pl)	2012-10-31
NO20020829D0 (no)	2002-02-20
HRP20020171A2 (en)	2004-02-29
KR100670416B1 (ko)	2007-01-17
WO2001015675A2 (en)	2001-03-08
JP2003508427A (ja)	2003-03-04

Publication	Publication Date	Title
EE200200087A (et)	2003-04-15	Kompositsioon hepatotsellulaarse kartsinoomi raviks
BR0312573A (pt)	2005-04-26	Derivados de fenil-[4-(3-fenil-1h-pirazol-4-il)-pirimidin-2-il]-amina
NO20034204D0 (no)	2003-09-22	Farmasöytiske kombinasjoner til behandling av kreft
MXPA05012323A (es)	2006-01-30	Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
DE60236541D1 (de)	2010-07-08	Inhibitoren von 11-beta-hydroxysteroiddehydrogenase typ 1
GB0223038D0 (en)	2002-11-13	Therapeutic compounds
PL1968573T3 (pl)	2011-07-29	Zastosowanie pochodnych benzo-skondensowanych heterocyklicznych sulfamidów do leczenia manii i zaburzenia afektywnego dwubiegunowego
GB0225474D0 (en)	2002-12-11	Therapeutic agents
ATE408601T1 (de)	2008-10-15	Fredericamycin-derivate
DE60336664D1 (de)	2011-05-19	Nichtnukleosidische reverse-transkriptase-hemmer
BRPI0508700A (pt)	2007-08-07	uso de sns-595, composição farmacêutica, e, pó liofilizado
SE9903759D0 (sv)	1999-10-18	Pharmaceutically active compounds
ATE478662T1 (de)	2010-09-15	Arzneilösungen enthaltend modafinilverbindungen
NO20032597D0 (no)	2003-06-06	Anvendelse av SARP-1 for behandlingen og/eller forebyggingen av skleroderma
SE0000303D0 (sv)	2000-01-31	Novel compounds
SE0203817D0 (sv)	2002-12-20	New composition
EA200700979A1 (ru)	2007-10-26	Пероральные твердые лекарственные формы, содержащие низкую дозу эстрадиола
DE60023321D1 (de)	2006-03-02	Zusammensetzung gegen Coccidiose
AU2016219620A1 (en)	2016-09-15	Compositions and methods useful for treatment of respiratory illness
UA95094C2 (ru)	2011-07-11	Применение бензоконденсированных гетероциклических сульфамидных производных для лечения маниакального синдрома и биполярного расстройства
TW200505836A (en)	2005-02-16	Cyclic sulfonamides for inhibition of gamma-secretase

Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2016-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20150829