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EE200100324A - Meetod aktiivse lümfotoksiin-beeta retseptori immunoglobuliinsete kimäärsete valkude kõrgtasemel ekspressiooniks ja puhastamiseks - Google Patents

Meetod aktiivse lümfotoksiin-beeta retseptori immunoglobuliinsete kimäärsete valkude kõrgtasemel ekspressiooniks ja puhastamiseks

Info

Publication number
EE200100324A
EE200100324A EEP200100324A EEP200100324A EE200100324A EE 200100324 A EE200100324 A EE 200100324A EE P200100324 A EEP200100324 A EE P200100324A EE P200100324 A EEP200100324 A EE P200100324A EE 200100324 A EE200100324 A EE 200100324A
Authority
EE
Estonia
Prior art keywords
purification
level expression
chimeric proteins
beta receptor
lymphotoxin beta
Prior art date
Application number
EEP200100324A
Other languages
English (en)
Inventor
L. Browning Jeffrey
Miatkowski Konrad
Meier Werner
Original Assignee
Biogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22345666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE200100324(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen, Inc. filed Critical Biogen, Inc.
Publication of EE200100324A publication Critical patent/EE200100324A/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
EEP200100324A 1998-12-17 1999-12-16 Meetod aktiivse lümfotoksiin-beeta retseptori immunoglobuliinsete kimäärsete valkude kõrgtasemel ekspressiooniks ja puhastamiseks EE200100324A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11275298P 1998-12-17 1998-12-17
PCT/US1999/029873 WO2000036092A2 (en) 1998-12-17 1999-12-16 METHOD FOR THE HIGH LEVEL EXPRESSION OF ACTIVE LYMPHOTOXIN-β RECEPTOR IMMUNOGLOBULIN CHIMERIC PROTEINS AND THEIR PURIFICATION

Publications (1)

Publication Number Publication Date
EE200100324A true EE200100324A (et) 2002-10-15

Family

ID=22345666

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100324A EE200100324A (et) 1998-12-17 1999-12-16 Meetod aktiivse lümfotoksiin-beeta retseptori immunoglobuliinsete kimäärsete valkude kõrgtasemel ekspressiooniks ja puhastamiseks

Country Status (27)

Country Link
US (3) US7585946B2 (et)
EP (3) EP1141248B1 (et)
JP (4) JP4878676B2 (et)
KR (3) KR20070091227A (et)
CN (2) CN100387708C (et)
AT (1) ATE536372T1 (et)
AU (2) AU777232B2 (et)
BR (1) BR9916325B1 (et)
CA (1) CA2354539A1 (et)
CY (1) CY1117003T1 (et)
CZ (1) CZ20012156A3 (et)
DK (2) DK1141248T3 (et)
EA (1) EA005270B1 (et)
EE (1) EE200100324A (et)
ES (1) ES2554482T5 (et)
HK (2) HK1038244A1 (et)
HU (1) HUP0200064A2 (et)
IL (3) IL143670A0 (et)
IS (1) IS5959A (et)
NO (1) NO20012991L (et)
NZ (3) NZ538599A (et)
PT (1) PT2374872E (et)
SG (1) SG123531A1 (et)
SI (1) SI2374872T2 (et)
SK (1) SK8552001A3 (et)
TR (2) TR200504220T2 (et)
WO (1) WO2000036092A2 (et)

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Also Published As

Publication number Publication date
JP2013116118A (ja) 2013-06-13
IL143670A0 (en) 2002-04-21
CN101289512A (zh) 2008-10-22
SI2374872T2 (sl) 2019-05-31
JP5777171B2 (ja) 2015-09-09
JP4878676B2 (ja) 2012-02-15
WO2000036092A2 (en) 2000-06-22
CN1333819A (zh) 2002-01-30
KR20070091227A (ko) 2007-09-07
ATE536372T1 (de) 2011-12-15
EA200100670A1 (ru) 2001-12-24
NO20012991L (no) 2001-08-17
SI2374872T1 (sl) 2016-03-31
TR200504220T2 (tr) 2007-04-24
IL205698A (en) 2015-11-30
SG123531A1 (en) 2006-07-26
EP2374872B1 (en) 2015-11-25
US20100136625A1 (en) 2010-06-03
CA2354539A1 (en) 2000-06-22
DK2374872T3 (en) 2015-12-14
HUP0200064A2 (en) 2002-05-29
US7585946B2 (en) 2009-09-08
ES2554482T5 (es) 2019-07-18
NZ538599A (en) 2007-11-30
CZ20012156A3 (cs) 2001-09-12
JP2010158252A (ja) 2010-07-22
NZ549623A (en) 2008-05-30
EP1141248A2 (en) 2001-10-10
WO2000036092A9 (en) 2002-08-22
JP2003517277A (ja) 2003-05-27
AU2005200042B2 (en) 2008-05-01
EP1141248B1 (en) 2011-12-07
US20020039580A1 (en) 2002-04-04
CY1117003T1 (el) 2017-04-05
DK1141248T3 (da) 2012-03-12
EP2374872B2 (en) 2019-02-20
HK1223398A1 (zh) 2017-07-28
IL229738A0 (en) 2014-01-30
DK2374872T4 (en) 2019-04-23
NZ529276A (en) 2005-03-24
KR20020013482A (ko) 2002-02-20
TR200101703T2 (tr) 2002-05-21
JP2014239697A (ja) 2014-12-25
BR9916325A (pt) 2001-10-02
KR100732934B1 (ko) 2007-06-29
US8709759B2 (en) 2014-04-29
AU777232B2 (en) 2004-10-07
AU2005200042A1 (en) 2005-02-03
EP2374872A3 (en) 2011-10-19
PT2374872E (pt) 2015-12-09
CN100387708C (zh) 2008-05-14
ES2554482T3 (es) 2015-12-21
KR20060084860A (ko) 2006-07-25
US8283138B2 (en) 2012-10-09
SK8552001A3 (en) 2001-12-03
EP2374872A2 (en) 2011-10-12
NO20012991D0 (no) 2001-06-15
EA005270B1 (ru) 2004-12-30
PL348816A1 (en) 2002-06-17
IS5959A (is) 2001-05-31
US20130196376A1 (en) 2013-08-01
EP3006563A1 (en) 2016-04-13
AU2364400A (en) 2000-07-03
BR9916325B1 (pt) 2011-06-28
HK1038244A1 (en) 2002-03-08
WO2000036092A3 (en) 2000-11-23

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