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EE04879B1 - Sünteetilised pindaktiivsed peptiidid ja nende kasutamine sünteetilise surfaktandi valmistamiseks - Google Patents

Sünteetilised pindaktiivsed peptiidid ja nende kasutamine sünteetilise surfaktandi valmistamiseks

Info

Publication number
EE04879B1
EE04879B1 EEP200100413A EEP200100413A EE04879B1 EE 04879 B1 EE04879 B1 EE 04879B1 EE P200100413 A EEP200100413 A EE P200100413A EE P200100413 A EEP200100413 A EE P200100413A EE 04879 B1 EE04879 B1 EE 04879B1
Authority
EE
Estonia
Prior art keywords
synthetic surfactants
preparation
surfactants
synthetic
Prior art date
Application number
EEP200100413A
Other languages
English (en)
Inventor
Curstedt Tore
Johansson Jan
J�rnvall Hans
Robertson Bengt
Ventura Paolo
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of EE200100413A publication Critical patent/EE200100413A/et
Publication of EE04879B1 publication Critical patent/EE04879B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200100413A 1999-02-12 2000-02-09 Sünteetilised pindaktiivsed peptiidid ja nende kasutamine sünteetilise surfaktandi valmistamiseks EE04879B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000275A IT1308180B1 (it) 1999-02-12 1999-02-12 Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
PCT/EP2000/001044 WO2000047623A1 (en) 1999-02-12 2000-02-09 Artificial peptides having surface activity and the use thereof in the preparation of artificial surfactant

Publications (2)

Publication Number Publication Date
EE200100413A EE200100413A (et) 2002-12-16
EE04879B1 true EE04879B1 (et) 2007-08-15

Family

ID=11381859

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100413A EE04879B1 (et) 1999-02-12 2000-02-09 Sünteetilised pindaktiivsed peptiidid ja nende kasutamine sünteetilise surfaktandi valmistamiseks

Country Status (33)

Country Link
US (1) US7053044B1 (et)
EP (1) EP1151008B1 (et)
JP (1) JP4754073B2 (et)
KR (1) KR100645145B1 (et)
CN (1) CN1221570C (et)
AR (1) AR022578A1 (et)
AT (1) ATE280181T1 (et)
AU (1) AU758735B2 (et)
BG (1) BG65196B1 (et)
BR (1) BR0009964A (et)
CA (1) CA2362507C (et)
CO (1) CO5241361A1 (et)
CZ (1) CZ301108B6 (et)
DE (1) DE60015082T2 (et)
EA (1) EA004058B1 (et)
EE (1) EE04879B1 (et)
ES (1) ES2228473T3 (et)
GE (1) GEP20032976B (et)
HK (1) HK1042500A1 (et)
HU (1) HU228997B1 (et)
IL (1) IL144842A0 (et)
IT (1) IT1308180B1 (et)
MA (1) MA25381A1 (et)
NO (1) NO20013888L (et)
NZ (1) NZ513451A (et)
PL (1) PL201084B1 (et)
PT (1) PT1151008E (et)
SK (1) SK286428B6 (et)
TR (1) TR200102308T2 (et)
UA (1) UA72751C2 (et)
WO (1) WO2000047623A1 (et)
YU (1) YU57701A (et)
ZA (1) ZA200106530B (et)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
US20030091509A1 (en) * 2000-02-11 2003-05-15 Haefner Dietrich Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases
DE60217060T2 (de) * 2002-03-01 2007-06-21 Chiesi Farmaceutici S.P.A. Pharmazeutische Zusammensetzungen, die Lungensurfactants und ein Polymyxin umfassen und verbesserte Oberflächenspannung-senkende Eigenschaften haben
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CA2507613A1 (en) * 2002-12-09 2004-07-08 Jeffrey A. Whitsett Methods of diagnosis and treatment of interstitial lung disease
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
JP2007504116A (ja) * 2003-08-28 2007-03-01 アルタナ　ファルマ　アクチエンゲゼルシャフト 外科的癒着の治療のためのサーファクタント調剤の使用
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
CA2658478C (en) 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
WO2008044109A1 (en) * 2006-10-13 2008-04-17 Chiesi Farmaceutici S.P.A. Reconstituted surfactants having improved properties
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
US8343912B2 (en) 2008-12-23 2013-01-01 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
EP2475373B1 (en) 2009-09-08 2013-11-13 Chiesi Farmaceutici S.p.A. A therapeutic combination comprising a pulmonary surfactant and antioxidant enzymes
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
NZ701073A (en) * 2012-04-23 2016-04-29 Chiesi Farma Spa Method and system for the administration of a pulmonary surfactant by atomization
KR102122088B1 (ko) 2012-11-21 2020-06-12 키에시 파르마슈티시 엣스. 피. 에이. 재구성된 폐 계면활성제
ES2827948T3 (es) 2015-04-22 2021-05-25 Chiesi Farm Spa Sistema eficaz para la administración de medicamento sincronizada con la respiración a los pulmones
EP3106090A1 (en) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
US11311691B2 (en) 2015-04-28 2022-04-26 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
US20180147262A1 (en) 2015-04-30 2018-05-31 University Of Bremen Novel skin medical and cosmetic care product
KR20190035682A (ko) 2016-07-28 2019-04-03 키에시 파르마슈티시 엣스. 피. 에이. 에어로졸화된 약제의 전달을 위한 방법 및 시스템
MX2019004394A (es) 2016-10-26 2019-07-15 Chiesi Farm Spa Dispositivo para facilitar la administracion de un medicamento al pulmon por un cateter.
RU2757902C2 (ru) 2016-12-22 2021-10-22 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Терапевтическая комбинация для лечения развивающейся bpd, содержащая легочный сурфактант и стероид
WO2019115771A1 (en) 2017-12-15 2019-06-20 Pari Pharma Gmbh Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
MA52353A (fr) 2018-04-23 2021-04-28 Chiesi Farm Spa Combinaison thérapeutique comprenant un tensioactif pulmonaire et un stéroïde pour la prophylaxie de la dbp
EP3666316A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3666315A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3843105A1 (en) 2019-12-23 2021-06-30 PARI Pharma GmbH Control device for aerosol nebulizer system
EP4097128A1 (en) 2020-01-28 2022-12-07 Chiesi Farmaceutici S.p.A. Polypeptides having improved properties
CN114159546B (zh) * 2021-12-20 2024-06-04 北京双鹤润创科技有限公司 新一代合成肺表面活性物质制剂及其临床应用
EP4411745A1 (en) 2023-02-01 2024-08-07 Pari Medical Holding GmbH Medical evaluation method, aerosol nebulizer and medical evaluation system
EP4464354A1 (en) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Method of operating an inhalation device, inhalation device and inhalation device system for providing inhalation process/breath guiding
EP4464236A1 (en) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Method of operating an inhalation device, inhalation device and inhalation device system for providing inhalation process feedback

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DK0733645T3 (da) * 1993-12-08 2003-07-14 Mitsubishi Pharma Corp Syntetisk peptid, lungeoverfladeaktivt stof indeholdende dette og præparat mod respiratory distress syndrome
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante

Also Published As

Publication number Publication date
CA2362507C (en) 2012-01-03
CZ301108B6 (cs) 2009-11-11
HUP0200141A3 (en) 2002-09-30
CO5241361A1 (es) 2003-01-31
PL201084B1 (pl) 2009-03-31
UA72751C2 (en) 2005-04-15
SK11442001A3 (sk) 2001-12-03
CA2362507A1 (en) 2000-08-17
PL349785A1 (en) 2002-09-09
AU758735B2 (en) 2003-03-27
IL144842A0 (en) 2002-06-30
DE60015082D1 (de) 2004-11-25
CN1221570C (zh) 2005-10-05
TR200102308T2 (tr) 2002-04-22
HU228997B1 (en) 2013-07-29
EP1151008B1 (en) 2004-10-20
NZ513451A (en) 2003-05-30
KR20010101904A (ko) 2001-11-15
NO20013888D0 (no) 2001-08-09
GEP20032976B (en) 2003-05-27
AR022578A1 (es) 2002-09-04
WO2000047623A1 (en) 2000-08-17
EP1151008A1 (en) 2001-11-07
JP2002541062A (ja) 2002-12-03
ES2228473T3 (es) 2005-04-16
HUP0200141A2 (en) 2002-06-29
HK1042500A1 (en) 2002-08-16
YU57701A (sh) 2003-07-07
SK286428B6 (sk) 2008-09-05
ATE280181T1 (de) 2004-11-15
EA200100749A1 (ru) 2002-02-28
AU3279300A (en) 2000-08-29
KR100645145B1 (ko) 2006-11-10
JP4754073B2 (ja) 2011-08-24
US7053044B1 (en) 2006-05-30
BR0009964A (pt) 2002-04-09
BG65196B1 (bg) 2007-06-29
MA25381A1 (fr) 2002-04-01
PT1151008E (pt) 2005-01-31
ITMI990275A1 (it) 2000-08-12
CZ20012876A3 (cs) 2002-06-12
DE60015082T2 (de) 2006-02-09
ZA200106530B (en) 2002-10-14
EA004058B1 (ru) 2003-12-25
EE200100413A (et) 2002-12-16
IT1308180B1 (it) 2001-12-07
NO20013888L (no) 2001-08-09
CN1340060A (zh) 2002-03-13
BG105764A (en) 2002-03-29

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231