EA202092349A1 - LACTITOL AND ORAL DOSAGE FORM FOR NON-ALCOHOLIC FATTY LIVER DISEASE - Google Patents
LACTITOL AND ORAL DOSAGE FORM FOR NON-ALCOHOLIC FATTY LIVER DISEASEInfo
- Publication number
- EA202092349A1 EA202092349A1 EA202092349A EA202092349A EA202092349A1 EA 202092349 A1 EA202092349 A1 EA 202092349A1 EA 202092349 A EA202092349 A EA 202092349A EA 202092349 A EA202092349 A EA 202092349A EA 202092349 A1 EA202092349 A1 EA 202092349A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- liver disease
- fatty liver
- alcoholic fatty
- lactitol
- dosage form
- Prior art date
Links
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 title abstract 3
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 title abstract 2
- 229960003451 lactitol Drugs 0.000 title abstract 2
- 235000010448 lactitol Nutrition 0.000 title abstract 2
- 239000000832 lactitol Substances 0.000 title abstract 2
- 239000006186 oral dosage form Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относится к области фармацевтической промышленности, а именно к применению лактитола в терапевтически эффективном количестве, предпочтительно в дозировке 1-20 г в сутки, для лечения и профилактики неалкогольной жировой болезни печени у млекопитающего, нуждающегося в этом. Изобретение обеспечивает расширение арсенала средств, эффективных в отношении терапии и профилактики неалкогольной жировой болезни печени.The invention relates to the pharmaceutical industry, namely to the use of lactitol in a therapeutically effective amount, preferably at a dosage of 1-20 g per day, for the treatment and prevention of non-alcoholic fatty liver disease in a mammal in need of it. EFFECT: invention provides an extension of the arsenal of agents effective for the treatment and prevention of non-alcoholic fatty liver disease.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2018111985A RU2692243C1 (en) | 2018-04-03 | 2018-04-03 | Using lactitol and an oral dosage form for treating and preventing non-alcoholic fatty liver disease |
PCT/RU2019/000157 WO2019194703A1 (en) | 2018-04-03 | 2019-03-13 | Lactitol and an oral pharmaceutical form for non-alcoholic fatty liver disease |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202092349A1 true EA202092349A1 (en) | 2020-12-22 |
Family
ID=67038280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202092349A EA202092349A1 (en) | 2018-04-03 | 2019-03-13 | LACTITOL AND ORAL DOSAGE FORM FOR NON-ALCOHOLIC FATTY LIVER DISEASE |
Country Status (5)
Country | Link |
---|---|
KR (1) | KR102569081B1 (en) |
CN (1) | CN111936148B (en) |
EA (1) | EA202092349A1 (en) |
RU (1) | RU2692243C1 (en) |
WO (1) | WO2019194703A1 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2113998B (en) * | 1982-02-05 | 1985-08-29 | Cv Chemie Combinatie Amsterdam | Lactitol for the treatment of liver disease |
WO2002039832A1 (en) * | 2000-11-17 | 2002-05-23 | Purac Biochem B.V. | Use of lactitol for improving intestinal microflora |
-
2018
- 2018-04-03 RU RU2018111985A patent/RU2692243C1/en active
-
2019
- 2019-03-13 CN CN201980023588.3A patent/CN111936148B/en active Active
- 2019-03-13 WO PCT/RU2019/000157 patent/WO2019194703A1/en active Application Filing
- 2019-03-13 EA EA202092349A patent/EA202092349A1/en unknown
- 2019-03-13 KR KR1020207031617A patent/KR102569081B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN111936148A (en) | 2020-11-13 |
KR20200140326A (en) | 2020-12-15 |
CN111936148B (en) | 2023-07-14 |
RU2692243C1 (en) | 2019-06-24 |
KR102569081B1 (en) | 2023-08-23 |
WO2019194703A1 (en) | 2019-10-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2021004431A (en) | Novel processes. | |
EA202090871A1 (en) | INHIBITION OF UBIKVITIN-SPECIFIC PEPTIDASE 30 | |
MX393855B (en) | COMBINATION THERAPY INCLUDING A RAF INHIBITOR AND TRAMETINIB | |
MA34474B1 (en) | AGONISTS OF GPR40 | |
MX2017010982A (en) | Use of pridopidine to improve cognitive function and for treating alzheimer's disease. | |
EA201691454A1 (en) | COMPOSITIONS OF PRIDOPIDININE MODIFIED SHIPPING | |
PH12015500375A1 (en) | Nep inhibitors for treating diseases characterized by atrial enlargemenet or remodeling | |
EA201300471A1 (en) | SUBSTITUTED 6-AMINONICOTINAMIDES AS KCNQ2 / 3 MODULATORS | |
RU2014111069A (en) | DOSAGE FORMS OF HISTONDIACETYLASE INHIBITOR IN COMBINATION WITH BENDAMUTIN AND THEIR APPLICATION | |
MA40768A (en) | MONO OR DI-SUBSTITUTE INDOLE DERIVATIVES AS DENGUE VIRUS REPLICATION INHIBITORS | |
BR112018005905A2 (en) | ? compound, pharmaceutical composition, methods to prevent or treat a disease or condition, organ damage, hepatotoxicity and fatty liver, and, use of a compound? | |
EA202090276A1 (en) | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ANEMIA | |
RU2018136872A (en) | COMPOSITIONS CONTAINING 15-OH EPA AND WAYS OF THEIR APPLICATION | |
EA201691555A1 (en) | METHODS OF TREATMENT AND PREVENTION OF KIDNEY DISEASES AND LIVER FATIAL DYSTROPHIES | |
PH12020551118A1 (en) | Modified lipidated relaxin b chain peptides and their therapeutic use | |
MA43052B1 (en) | Human Plasma Kallikrein Inhibitors | |
MA53010B1 (en) | FORMULATIONS OF AN AXL/MER INHIBITOR | |
PH12019500618A1 (en) | Pharmaceutical composition and method for treatment of non-alcoholic fatty liver disease | |
EA202192199A1 (en) | COMPOSITIONS CONTAINING CINNAMIC ACID AND METHODS OF THEIR APPLICATION | |
EA202190429A1 (en) | Bioavailable oral dosage forms | |
MX395613B (en) | ZINC-AND-PGA COMPOSITIONS AND METHODS FOR TREATING CANCER. | |
MA41985B1 (en) | Composition for cleansing the colon and treating gastrointestinal disorders | |
MA49839B1 (en) | Bicyclic histone deacetylase inhibitors | |
EA202090666A1 (en) | APPLICATION OF BENZOATE-CONTAINING COMPOSITION FOR TREATMENT OF GLYCINE ENCEPHALOPATHY | |
MA39448A1 (en) | (R) -pirlindole and its pharmaceutically acceptable salts for medical use |