EA202092110A1 - AMINO ACID COMPOUNDS AND METHODS OF APPLICATION - Google Patents
AMINO ACID COMPOUNDS AND METHODS OF APPLICATIONInfo
- Publication number
- EA202092110A1 EA202092110A1 EA202092110A EA202092110A EA202092110A1 EA 202092110 A1 EA202092110 A1 EA 202092110A1 EA 202092110 A EA202092110 A EA 202092110A EA 202092110 A EA202092110 A EA 202092110A EA 202092110 A1 EA202092110 A1 EA 202092110A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- methods
- application
- amino acid
- acid compounds
- formula
- Prior art date
Links
- -1 AMINO ACID COMPOUNDS Chemical class 0.000 title 1
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000036971 interstitial lung disease 2 Diseases 0.000 abstract 2
- 201000004071 non-specific interstitial pneumonia Diseases 0.000 abstract 2
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 102000006495 integrins Human genes 0.000 abstract 1
- 108010044426 integrins Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Данное изобретение относится к соединениям формулы (А) и формулы (I)или к их солям, где R1, R2, R10, R11, R12, R13, R14, R15, R16, q и р являются такими, как описано в данном документе. Соединения формулы (A), формулы (I) и их фармацевтические композиции являются ингибиторами интегрина v6, которые пригодны для лечения фиброза, такого как идиопатический фиброз легких (IPF) и неспецифическая интерстициальная пневмония (NSIP).This invention relates to compounds of formula (A) and formula (I) or salts thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. The compounds of formula (A), formula (I) and pharmaceutical compositions thereof are inhibitors of v6 integrin which are useful in the treatment of fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862690933P | 2018-06-27 | 2018-06-27 | |
| PCT/US2019/021243 WO2019173653A1 (en) | 2018-03-07 | 2019-03-07 | Amino acid compounds and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202092110A1 true EA202092110A1 (en) | 2021-02-15 |
Family
ID=74855473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202092110A EA202092110A1 (en) | 2018-06-27 | 2019-03-07 | AMINO ACID COMPOUNDS AND METHODS OF APPLICATION |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA202092110A1 (en) |
-
2019
- 2019-03-07 EA EA202092110A patent/EA202092110A1/en unknown
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