EA201991340A1 - Способы индуцирования иммунологической толерантности к факторам свертывания крови - Google Patents
Способы индуцирования иммунологической толерантности к факторам свертывания кровиInfo
- Publication number
- EA201991340A1 EA201991340A1 EA201991340A EA201991340A EA201991340A1 EA 201991340 A1 EA201991340 A1 EA 201991340A1 EA 201991340 A EA201991340 A EA 201991340A EA 201991340 A EA201991340 A EA 201991340A EA 201991340 A1 EA201991340 A1 EA 201991340A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- blood
- coaging
- factors
- methods
- immunological tolerance
- Prior art date
Links
- 230000001900 immune effect Effects 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 abstract 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 abstract 1
- 239000003114 blood coagulation factor Substances 0.000 abstract 1
- 229940019700 blood coagulation factors Drugs 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
В настоящем изобретении предусмотрены способы индуцирования иммунологической толерантности у человека, включающие введение человеку эффективного количества композиции или химерного белка, содержащих фактор свертывания крови и Fc-область.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762582829P | 2017-11-07 | 2017-11-07 | |
| PCT/US2017/064323 WO2018102760A1 (en) | 2016-12-02 | 2017-12-01 | Methods of inducing immune tolerance to clotting factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201991340A1 true EA201991340A1 (ru) | 2019-11-29 |
Family
ID=68653614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201991340A EA201991340A1 (ru) | 2017-11-07 | 2017-12-01 | Способы индуцирования иммунологической толерантности к факторам свертывания крови |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA201991340A1 (ru) |
-
2017
- 2017-12-01 EA EA201991340A patent/EA201991340A1/ru unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2023015185A (es) | Degradadores de proteinas y usos de los mismos. | |
| GEP20217326B (en) | Constructs having a sirp-alpha domain or variant thereof | |
| MX2021006017A (es) | Polipeptidos de folistatina y sus usos. | |
| EP4421094A3 (en) | Targeted therapeutic agents and uses thereof | |
| PH12019502763A1 (en) | Anti-human papillomavirus (hpv) antigen-binding proteins and methods of use thereof | |
| EA201792573A1 (ru) | Триспецифические связанные белки и способы их применения | |
| EA201792221A1 (ru) | Антитела против сортилина и способы их применения | |
| EA201890145A1 (ru) | Антитела к фактору xi и способы их применения | |
| EA201791775A1 (ru) | Цистеиновая протеаза | |
| EA201890453A1 (ru) | Анти-angptl8 антитела и их применение | |
| EA201991207A1 (ru) | Новые агонисты tnfr и их применение | |
| UA118029C2 (uk) | Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування | |
| EA201790273A1 (ru) | Флагеллиновые композиции и их применение | |
| EA201690159A1 (ru) | Способы и композиции для лечения рака | |
| EA202190138A1 (ru) | Анти-sirp-бета1 антитела и способы их использования | |
| WO2016061504A3 (en) | Recombinant antibodies that recongnize the c-terminal domains of ebola virus nucleoprotein | |
| EA201790336A1 (ru) | Антитела к ангиопоэтинподобному белку 4 и способы применения | |
| MX2020007628A (es) | Composiciones y metodos de uso. | |
| EA202092085A1 (ru) | ТЕРАПЕВТИЧЕСКИЕ АНТИТЕЛА ПРОТИВ sPLA2-GIB И ИХ ПРИМЕНЕНИЕ | |
| NZ754971A (en) | Methods of treating hemophilic arthropathy using chimeric clotting factors | |
| ECSP20083339A (es) | Proteínas inmunodominantes y fragmentos en esclerosis múltiple | |
| TW201613977A (en) | Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use | |
| MX2019006446A (es) | Métodos para inducir tolerancia inmunológica a factores de coagulación. | |
| EA202191758A1 (ru) | Пептиды для лечения и профилактики диабета и связанных с ним заболеваний | |
| EA202191058A1 (ru) | Антитела против муцина-16 и способы их применения |