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EA201791590A1 - Антитела к tau и их применение - Google Patents

Антитела к tau и их применение

Info

Publication number
EA201791590A1
EA201791590A1 EA201791590A EA201791590A EA201791590A1 EA 201791590 A1 EA201791590 A1 EA 201791590A1 EA 201791590 A EA201791590 A EA 201791590A EA 201791590 A EA201791590 A EA 201791590A EA 201791590 A1 EA201791590 A1 EA 201791590A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tau
antibodies
application
disease
pick
Prior art date
Application number
EA201791590A
Other languages
English (en)
Other versions
EA033433B1 (ru
Inventor
Альберто Альварадо
Дэвид Драйвер
Мансуо Лу Хаяши
Цзижун Лу
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA201791590A1 publication Critical patent/EA201791590A1/ru
Publication of EA033433B1 publication Critical patent/EA033433B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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Abstract

Моноклональные антитела к агрегату tau человека, композиции, содержащие такие антитела к tau, и способы применения таких антител к tau для лечения нейродегенеративных заболеваний, включая болезнь Альцгеймера, прогрессирующий надъядерный паралич и болезнь Пика.
EA201791590A 2015-02-26 2016-02-18 Антитела к tau и их применение EA033433B1 (ru)

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