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EA201691866A1 - Проникающие в опухоль лимфоциты для адоптивной клеточной терапии - Google Patents

Проникающие в опухоль лимфоциты для адоптивной клеточной терапии

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Publication number
EA201691866A1
EA201691866A1 EA201691866A EA201691866A EA201691866A1 EA 201691866 A1 EA201691866 A1 EA 201691866A1 EA 201691866 A EA201691866 A EA 201691866A EA 201691866 A EA201691866 A EA 201691866A EA 201691866 A1 EA201691866 A1 EA 201691866A1
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Eurasian Patent Office
Prior art keywords
cell therapy
lymphocytes
permitting
tumor
methods
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EA201691866A
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English (en)
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EA036386B1 (ru
Inventor
Амод А. Сарнейк
Шари Пайлон-Томас
Марк Маклафлин
Хао ЛЮ
Original Assignee
Х. Ли Моффитт Кэнсер Сентер Энд Рисёч Инститьют, Инк.
Юнивёрсити Оф Саус Флорида
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Application filed by Х. Ли Моффитт Кэнсер Сентер Энд Рисёч Инститьют, Инк., Юнивёрсити Оф Саус Флорида filed Critical Х. Ли Моффитт Кэнсер Сентер Энд Рисёч Инститьют, Инк.
Publication of EA201691866A1 publication Critical patent/EA201691866A1/ru
Publication of EA036386B1 publication Critical patent/EA036386B1/ru

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Abstract

В заявке описываются композиции и способы наращивания проникающих в опухоль лимфоцитов ex vivo с целью их применения при адоптивной клеточной терапии (АКТ). Также описываются композиции и способы идентификации агента для наращивания проникающих в опухоль лимфоцитов ex vivo с целью их применения при АКТ. Также в изобретении предлагаются способы лечения рака с применением проникающих в опухоль лимфоцитов, нарощенных с помощью описанных в настоящем документе способов.
EA201691866A 2014-03-20 2015-03-20 Проникающие в опухоль лимфоциты для адоптивной клеточной терапии EA036386B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461955970P 2014-03-20 2014-03-20
US201461973002P 2014-03-31 2014-03-31
PCT/US2015/021759 WO2015143328A1 (en) 2014-03-20 2015-03-20 Tumor-infiltrating lymphocytes for adoptive cell therapy

Publications (2)

Publication Number Publication Date
EA201691866A1 true EA201691866A1 (ru) 2017-01-30
EA036386B1 EA036386B1 (ru) 2020-11-03

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EA201691866A EA036386B1 (ru) 2014-03-20 2015-03-20 Проникающие в опухоль лимфоциты для адоптивной клеточной терапии

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US (3) US20170081635A1 (ru)
EP (2) EP3698850A1 (ru)
JP (4) JP2017511375A (ru)
KR (3) KR20160146713A (ru)
CN (2) CN112080467A (ru)
AU (3) AU2015231041B2 (ru)
CA (1) CA2943389C (ru)
EA (1) EA036386B1 (ru)
ES (1) ES2776407T3 (ru)
MX (2) MX374472B (ru)
WO (1) WO2015143328A1 (ru)

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EP3119477A4 (en) 2018-03-07
EP3119477A1 (en) 2017-01-25
CA2943389C (en) 2023-10-31
EP3698850A1 (en) 2020-08-26
AU2015231041B2 (en) 2020-07-16
AU2015231041A1 (en) 2016-11-03
KR20250004905A (ko) 2025-01-08
JP2023123877A (ja) 2023-09-05
CN106659913A (zh) 2017-05-10
JP2017511375A (ja) 2017-04-20
MX374472B (es) 2025-03-06
US20220282215A1 (en) 2022-09-08
EA036386B1 (ru) 2020-11-03
AU2023200308A1 (en) 2023-03-02
US12291724B2 (en) 2025-05-06
US11518980B2 (en) 2022-12-06
AU2020256412A1 (en) 2020-11-26
KR20230085225A (ko) 2023-06-13
ES2776407T3 (es) 2020-07-30
JP2025041755A (ja) 2025-03-26
EP3119477B1 (en) 2020-01-01
NZ762786A (en) 2024-05-31
US20190177693A1 (en) 2019-06-13
MX2020005634A (es) 2020-08-20
BR112016021370A2 (pt) 2017-08-15
WO2015143328A1 (en) 2015-09-24
US20170081635A1 (en) 2017-03-23
CA2943389A1 (en) 2015-09-24
MX2016012176A (es) 2017-04-13
KR20160146713A (ko) 2016-12-21
JP2020182477A (ja) 2020-11-12
CN112080467A (zh) 2020-12-15
BR112016021370A8 (pt) 2021-07-20

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