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EA201070193A1 - Лечение детских опухолей - Google Patents

Лечение детских опухолей

Info

Publication number
EA201070193A1
EA201070193A1 EA201070193A EA201070193A EA201070193A1 EA 201070193 A1 EA201070193 A1 EA 201070193A1 EA 201070193 A EA201070193 A EA 201070193A EA 201070193 A EA201070193 A EA 201070193A EA 201070193 A1 EA201070193 A1 EA 201070193A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tumors
children
treatment
pnet
neuroblastomas
Prior art date
Application number
EA201070193A
Other languages
English (en)
Other versions
EA015933B1 (ru
Inventor
Клаудио Пизано
Лоредана Веши
Паоло Карминати
Original Assignee
Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. filed Critical Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.
Publication of EA201070193A1 publication Critical patent/EA201070193A1/ru
Publication of EA015933B1 publication Critical patent/EA015933B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

В изобретении раскрыт подкласс производных камптотецина, применимых для получения лекарственного средства, предназначенного для лечения опухолей у детей, например рабдомиосаркомы, примитивных нейроэктодермальных опухолей (PNET) и нейробластомы.
EA201070193A 2007-08-01 2008-07-03 Лечение детских опухолей EA015933B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07113603 2007-08-01
PCT/EP2008/058601 WO2009015981A2 (en) 2007-08-01 2008-07-03 Treatment of pediatric tumors

Publications (2)

Publication Number Publication Date
EA201070193A1 true EA201070193A1 (ru) 2010-06-30
EA015933B1 EA015933B1 (ru) 2011-12-30

Family

ID=38799381

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070193A EA015933B1 (ru) 2007-08-01 2008-07-03 Лечение детских опухолей

Country Status (11)

Country Link
US (1) US8829021B2 (ru)
EP (1) EP2182951A2 (ru)
JP (2) JP5765937B2 (ru)
KR (1) KR20100051837A (ru)
CN (1) CN101784277A (ru)
BR (1) BRPI0815051A2 (ru)
CA (1) CA2694389C (ru)
EA (1) EA015933B1 (ru)
MX (1) MX2010001084A (ru)
SG (1) SG183010A1 (ru)
WO (1) WO2009015981A2 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014070767A1 (en) 2012-10-29 2014-05-08 Arizona Board Of Regents On Behalf Of University Of Arizona Predictive markers for polyamine inhibitor cancer therapies
CA2952771A1 (en) 2014-06-18 2015-12-23 Arizona Board Of Regents On Behalf Of The University Of Arizona Carcinoma diagnosis and treatment based on odc1 genotype
JP2018507910A (ja) * 2015-02-12 2018-03-22 ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ジ・ユニバーシティ・オブ・アリゾナ 神経芽細胞腫を治療する方法
BR112018008651A2 (pt) 2015-10-30 2018-10-30 Cancer Prevention Pharmaceuticals Inc formulação de combinação de dose fixa de eflornitina e sulindaco
JP2022532766A (ja) 2019-05-17 2022-07-19 キャンサー プリベンション ファーマシューティカルズ,インコーポレイテッド 家族性腺腫性ポリポーシスを処置するための方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1044977E (pt) * 1999-03-09 2002-09-30 Sigma Tau Ind Farmaceuti Derivados de camptotecina com actividade antitumoral
SI1962850T1 (sl) 2005-12-21 2012-06-29 Sigma Tau Ind Farmaceuti Zdravljenje tumorjev, odpornih proti zdravilom
WO2008098701A1 (en) 2007-02-13 2008-08-21 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Broad-spectrum anti-cancer treatment based on iminocamptothecin derivatives

Also Published As

Publication number Publication date
WO2009015981A2 (en) 2009-02-05
SG183010A1 (en) 2012-08-30
CA2694389A1 (en) 2009-02-05
US8829021B2 (en) 2014-09-09
KR20100051837A (ko) 2010-05-18
WO2009015981A3 (en) 2009-09-03
AU2008282024A1 (en) 2009-02-05
EA015933B1 (ru) 2011-12-30
MX2010001084A (es) 2010-03-25
JP2014111653A (ja) 2014-06-19
JP2010534699A (ja) 2010-11-11
CN101784277A (zh) 2010-07-21
CA2694389C (en) 2016-01-19
US20100197718A1 (en) 2010-08-05
BRPI0815051A2 (pt) 2015-02-10
JP5765937B2 (ja) 2015-08-19
EP2182951A2 (en) 2010-05-12

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU