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EA200800886A1 - Способ получения 1-н-имидазо[4,5-с]пиридинов и их аналогов - Google Patents

Способ получения 1-н-имидазо[4,5-с]пиридинов и их аналогов

Info

Publication number
EA200800886A1
EA200800886A1 EA200800886A EA200800886A EA200800886A1 EA 200800886 A1 EA200800886 A1 EA 200800886A1 EA 200800886 A EA200800886 A EA 200800886A EA 200800886 A EA200800886 A EA 200800886A EA 200800886 A1 EA200800886 A1 EA 200800886A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compound
formula
imidazo
analogs
pyridine
Prior art date
Application number
EA200800886A
Other languages
English (en)
Other versions
EA014244B1 (ru
Inventor
Ларри Р. Крепски
Грегори Дж. Марсзалек
Соня С. Макки
Джон Ф. Герстер
Original Assignee
Коли Фармасьютикал Груп, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Коли Фармасьютикал Груп, Инк. filed Critical Коли Фармасьютикал Груп, Инк.
Publication of EA200800886A1 publication Critical patent/EA200800886A1/ru
Publication of EA014244B1 publication Critical patent/EA014244B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Описаны способы и промежуточные продукты для получения соединений формул (I и X). Способы включают способ получения соединения формулы (IV) и превращения соединения формулы IV в соединение формулы I, способ получения соединения формулы (VIII) и превращения соединения формулы VIII в соединение формулы I и способ получения соединения формулы (XI) и превращения соединения формулы XI в соединение формулы I.
EA200800886A 2005-09-23 2006-09-22 СПОСОБ ПОЛУЧЕНИЯ 1-Н-ИМИДАЗО[4,5-c]ПИРИДИНОВ И ИХ АНАЛОГОВ EA014244B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72017105P 2005-09-23 2005-09-23
US74350506P 2006-03-16 2006-03-16
PCT/US2006/037317 WO2007035935A1 (en) 2005-09-23 2006-09-22 METHOD FOR 1H-IMIDAZO[4,5-c]PYRIDINES AND ANALOGS THEREOF

Publications (2)

Publication Number Publication Date
EA200800886A1 true EA200800886A1 (ru) 2008-08-29
EA014244B1 EA014244B1 (ru) 2010-10-29

Family

ID=37889149

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800886A EA014244B1 (ru) 2005-09-23 2006-09-22 СПОСОБ ПОЛУЧЕНИЯ 1-Н-ИМИДАЗО[4,5-c]ПИРИДИНОВ И ИХ АНАЛОГОВ

Country Status (10)

Country Link
US (1) US20090240055A1 (ru)
EP (1) EP1937683A4 (ru)
JP (1) JP4551962B2 (ru)
KR (1) KR20080048551A (ru)
AU (1) AU2006292119A1 (ru)
BR (1) BRPI0616338A2 (ru)
CA (1) CA2623541A1 (ru)
EA (1) EA014244B1 (ru)
IL (1) IL190402A0 (ru)
WO (1) WO2007035935A1 (ru)

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Also Published As

Publication number Publication date
JP2009509971A (ja) 2009-03-12
BRPI0616338A2 (pt) 2011-06-14
IL190402A0 (en) 2008-11-03
WO2007035935A1 (en) 2007-03-29
AU2006292119A8 (en) 2008-05-29
KR20080048551A (ko) 2008-06-02
US20090240055A1 (en) 2009-09-24
JP4551962B2 (ja) 2010-09-29
EA014244B1 (ru) 2010-10-29
EP1937683A4 (en) 2010-08-25
EP1937683A1 (en) 2008-07-02
AU2006292119A1 (en) 2007-03-29
CA2623541A1 (en) 2007-03-29

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