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EA200500126A1 - COMPOSITIONS AND METHODS OF TREATMENT OF SEXUAL DYSFUNCTION IN WOMEN - Google Patents

COMPOSITIONS AND METHODS OF TREATMENT OF SEXUAL DYSFUNCTION IN WOMEN

Info

Publication number
EA200500126A1
EA200500126A1 EA200500126A EA200500126A EA200500126A1 EA 200500126 A1 EA200500126 A1 EA 200500126A1 EA 200500126 A EA200500126 A EA 200500126A EA 200500126 A EA200500126 A EA 200500126A EA 200500126 A1 EA200500126 A1 EA 200500126A1
Authority
EA
Eurasian Patent Office
Prior art keywords
women
treatment
sexual dysfunction
methods
compositions
Prior art date
Application number
EA200500126A
Other languages
Russian (ru)
Other versions
EA008720B1 (en
Inventor
Джеймс Л. Йигер
Надир Буюктимкин
Сервет Буюктимкин
Мингки Лу
Й. Джозеф Мо
Original Assignee
Нексмед (Холдингс), Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/208,965 external-priority patent/US6486207B2/en
Priority claimed from US10/188,554 external-priority patent/US6825234B2/en
Application filed by Нексмед (Холдингс), Инк. filed Critical Нексмед (Холдингс), Инк.
Publication of EA200500126A1 publication Critical patent/EA200500126A1/en
Publication of EA008720B1 publication Critical patent/EA008720B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение обеспечивает композиции и способы, подходящие для лечения сексуальной дисфункции у женщин и, в частности, расстройства сексуального возбуждения у женщин. В одном варианте воплощения изобретение обеспечивает полутвердую композицию, подходящую для местного нанесения, включающую эффективное количество вазоактивного простагландина, усилитель пенетрации, полимерный загуститель, липофильный компонент и кислотную буферную систему.Международная заявка была опубликована вместе с отчетом о международном поиске.The invention provides compositions and methods suitable for the treatment of sexual dysfunction in women and, in particular, disorders of sexual arousal in women. In one embodiment, the invention provides a semi-solid composition suitable for topical application, comprising an effective amount of vasoactive prostaglandin, a penetration enhancer, a polymeric thickener, a lipophilic component, and an acid buffer system. The international application was published along with an international search report.

EA200500126A 1998-12-10 2003-07-02 Use of a prostaglandin-based composition for amelioration of human female sexual dysfunction EA008720B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/208,965 US6486207B2 (en) 1998-12-10 1998-12-10 Compositions and methods for amelioration of human female sexual dysfunction
US10/188,554 US6825234B2 (en) 1998-12-10 2002-07-02 Compositions and methods for amelioration of human female sexual dysfunction
PCT/US2003/020779 WO2004004689A1 (en) 2002-07-02 2003-07-02 Compositions and methods for amelioration of human female sexual dysfunction

Publications (2)

Publication Number Publication Date
EA200500126A1 true EA200500126A1 (en) 2005-06-30
EA008720B1 EA008720B1 (en) 2007-06-29

Family

ID=33554763

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500126A EA008720B1 (en) 1998-12-10 2003-07-02 Use of a prostaglandin-based composition for amelioration of human female sexual dysfunction

Country Status (1)

Country Link
EA (1) EA008720B1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6414028B1 (en) * 1997-11-05 2002-07-02 Nexmed Holdings, Inc. Topical compositions containing prostaglandin E1
US6046244A (en) * 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
US6486207B2 (en) * 1998-12-10 2002-11-26 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US6323241B1 (en) * 2000-01-10 2001-11-27 Nexmed (Holdings) Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
US6693135B2 (en) * 2000-01-10 2004-02-17 Nexmed (Holdings) Incorporated Prostaglandin compositions and methods of treatment for male erectile dysfunction

Also Published As

Publication number Publication date
EA008720B1 (en) 2007-06-29

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): AM AZ BY KZ MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ MD TJ TM RU