[go: up one dir, main page]

EA200400877A1 - 2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидиновые производные и их применение для лечения недержания мочи - Google Patents

2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидиновые производные и их применение для лечения недержания мочи

Info

Publication number
EA200400877A1
EA200400877A1 EA200400877A EA200400877A EA200400877A1 EA 200400877 A1 EA200400877 A1 EA 200400877A1 EA 200400877 A EA200400877 A EA 200400877A EA 200400877 A EA200400877 A EA 200400877A EA 200400877 A1 EA200400877 A1 EA 200400877A1
Authority
EA
Eurasian Patent Office
Prior art keywords
dialkoxifen
ilimino
galo
utilization
treatment
Prior art date
Application number
EA200400877A
Other languages
English (en)
Inventor
Франц Эссер
Паскаль Пузе
Наоки Ишигуро
Хисато Китагава
Икунобу Мураматсу
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг filed Critical Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Publication of EA200400877A1 publication Critical patent/EA200400877A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

В заявке описаны 2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидин, его таутомер 2'-гало-3',5'-диалкоксианилино-2-имидазолин и их фармацевтически приемлемые соли и применение этих соединений в составе фармацевтических композиций.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200400877A 2002-01-31 2002-12-16 2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидиновые производные и их применение для лечения недержания мочи EA200400877A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02002352A EP1333028A1 (en) 2002-01-31 2002-01-31 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
PCT/EP2002/014299 WO2003064398A1 (en) 2002-01-31 2002-12-16 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence

Publications (1)

Publication Number Publication Date
EA200400877A1 true EA200400877A1 (ru) 2005-02-24

Family

ID=8185397

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400877A EA200400877A1 (ru) 2002-01-31 2002-12-16 2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидиновые производные и их применение для лечения недержания мочи

Country Status (20)

Country Link
EP (2) EP1333028A1 (ru)
JP (1) JP2005516066A (ru)
KR (1) KR20040074134A (ru)
CN (1) CN1617857A (ru)
AR (1) AR038380A1 (ru)
BR (1) BR0215560A (ru)
CA (1) CA2474588A1 (ru)
EA (1) EA200400877A1 (ru)
EC (1) ECSP045210A (ru)
HR (1) HRP20040691A2 (ru)
HU (1) HUP0402654A2 (ru)
IL (1) IL162776A0 (ru)
MX (1) MXPA04007250A (ru)
NO (1) NO20043614L (ru)
PE (1) PE20030819A1 (ru)
PL (1) PL369826A1 (ru)
TW (1) TW200418462A (ru)
UY (1) UY27628A1 (ru)
WO (1) WO2003064398A1 (ru)
ZA (1) ZA200405173B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4168086B1 (ja) * 2008-04-16 2008-10-22 国立大学法人福井大学 イミダゾリン誘導体
CA2724293A1 (en) * 2008-05-13 2009-11-19 Allergan, Inc. Quinolynylmethylimidizoles as therapeutic agents
CA2724290A1 (en) * 2008-05-13 2009-11-19 Allergan, Inc. Naphthylmethylimidizoles for the treatment of stress urinary incontinence
US8063231B2 (en) * 2008-06-09 2011-11-22 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions
ES2665293T3 (es) * 2008-06-09 2018-04-25 Allergan, Inc. Compuesto para tratar estados con mediación alfa-adrenérgica
US9034910B2 (en) 2008-06-09 2015-05-19 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2220906A1 (de) * 1972-04-28 1973-11-15 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2259160A1 (de) * 1972-12-02 1974-06-06 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline, deren saeureadditionssalze und verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel
AT333749B (de) * 1974-07-03 1976-12-10 Chemie Linz Ag Verfahren zur herstellung von neuen 2-arylamino-2-imidazolinderivaten
MTP837B (en) * 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE3514351A1 (de) * 1985-04-20 1986-11-06 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte 2-(n-alkinyl-n-phenyl)amino)-imidazolinderivate, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
DE19740176C2 (de) * 1997-09-12 2000-04-06 Lemfoerder Metallwaren Ag Handschaltvorrichtung für ein Kraftfahrzeug

Also Published As

Publication number Publication date
BR0215560A (pt) 2004-12-21
NO20043614L (no) 2004-08-30
ZA200405173B (en) 2005-06-21
WO2003064398A1 (en) 2003-08-07
UY27628A1 (es) 2003-08-29
MXPA04007250A (es) 2004-10-29
HUP0402654A2 (hu) 2005-03-29
TW200418462A (en) 2004-10-01
CA2474588A1 (en) 2003-08-07
PL369826A1 (en) 2005-05-02
ECSP045210A (es) 2004-09-28
EP1333028A1 (en) 2003-08-06
AR038380A1 (es) 2005-01-12
CN1617857A (zh) 2005-05-18
HRP20040691A2 (en) 2004-12-31
JP2005516066A (ja) 2005-06-02
EP1472231A1 (en) 2004-11-03
IL162776A0 (en) 2005-11-20
PE20030819A1 (es) 2003-10-20
KR20040074134A (ko) 2004-08-21

Similar Documents

Publication Publication Date Title
EA200501009A1 (ru) Замещённые пирролопиразольные производные в качестве ингибиторов киназы
EA200100688A1 (ru) АЗОТСОДЕРЖАЩИЕ ГЕТЕРОБИЦИКЛЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ФАКТОРА Xa
EA200600928A1 (ru) Фармацевтически приемлемые соли хинолиноновых соединений с улучшенными фармацевтическими свойствами
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
BRPI0416692A (pt) inibidores heterocìclicos de mek e métodos de emprego destes
EA200200619A1 (ru) Непептидильные ингибиторы vla-4-зависимого связывания клеток, применяемые при лечении воспалительных, аутоимунных и респираторных заболеваний
EA200300248A1 (ru) Бициклопиразолы, активные в качестве ингибиторов киназы, способ их получения и включающие их фармацевтические композиции
ATE302775T1 (de) Carbolinderivate
SE0202463D0 (sv) Novel compounds
EA199800340A1 (ru) Производные пиримидина как антагонисты 5нт2с
MY137156A (en) Dual nk1/nk3 derivatives
SE9900961D0 (sv) Novel compounds
DE60112306D1 (de) Kondensierte pyrazindionderivate als pde5 inhibitore
ATE346067T1 (de) Carbolinderivate
SE0402762D0 (sv) Indazole sulphonamide derivatives
DE60121461D1 (de) Kondensierte pyridoindolderivate
ECSP055701A (es) Nuevos derivados de pirimidinamida y el uso de los mismos
ECSP055809A (es) Inhibidores 4-oxo-1-(3-fenil sustituido)-1,4-dihidro-1,8-naftiridina-3-carboxamida de la fosfodiesterasa-4
ATE359791T1 (de) Pyrimidin-2,4-dion-derivate als matrix- metalloproteinase-hemmer
SE9802208D0 (sv) Novel compounds
EA200200876A1 (ru) Алкилированные производные имидазопиридина
SE0302573D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
EA200400086A1 (ru) Новые производные оксазолидинонов в качестве антибактериальных агентов
PE20030061A1 (es) 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
EA200400530A1 (ru) Перекрестно-сшитые антибиотики "гликопептид-цефалоспорин"