EA200400591A1 - СПОСОБ ВВЕДЕНИЯ ПЕПТИДА ТИМОЗИН α1 - Google Patents
СПОСОБ ВВЕДЕНИЯ ПЕПТИДА ТИМОЗИН α1Info
- Publication number
- EA200400591A1 EA200400591A1 EA200400591A EA200400591A EA200400591A1 EA 200400591 A1 EA200400591 A1 EA 200400591A1 EA 200400591 A EA200400591 A EA 200400591A EA 200400591 A EA200400591 A EA 200400591A EA 200400591 A1 EA200400591 A1 EA 200400591A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- administrating
- peptide
- peptide thymosin
- patient
- thymosin
- Prior art date
Links
- 108010078233 Thymalfasin Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 102400000800 Thymosin alpha-1 Human genes 0.000 abstract 2
- NZVYCXVTEHPMHE-ZSUJOUNUSA-N thymalfasin Chemical compound CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O NZVYCXVTEHPMHE-ZSUJOUNUSA-N 0.000 abstract 2
- 229960004231 thymalfasin Drugs 0.000 abstract 2
- 238000001802 infusion Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Пептид тимозин α(TA1) вводят пациенту, нуждающемуся в иммунной стимуляции таким образом, чтобы по сути непрерывно поддерживать иммуностимулирующее эффективное количество пептида TA1 у пациента. Способом введения может быть непрерывная инфузия.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33087401P | 2001-11-01 | 2001-11-01 | |
PCT/US2002/035093 WO2003037366A1 (en) | 2001-11-01 | 2002-11-01 | Method of administering a thymosin alpha 1 peptide |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200400591A1 true EA200400591A1 (ru) | 2004-10-28 |
EA008536B1 EA008536B1 (ru) | 2007-06-29 |
Family
ID=23291672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200400591A EA008536B1 (ru) | 2001-11-01 | 2002-11-01 | СПОСОБ ВВЕДЕНИЯ ПЕПТИДА ТИМОЗИНА α |
Country Status (19)
Country | Link |
---|---|
US (2) | US20050049191A1 (ru) |
EP (1) | EP1450850B1 (ru) |
JP (1) | JP2005511563A (ru) |
KR (1) | KR20050042229A (ru) |
CN (1) | CN1582163A (ru) |
AT (1) | ATE481980T1 (ru) |
AU (1) | AU2002363248B2 (ru) |
BR (1) | BR0213823A (ru) |
CA (1) | CA2464307A1 (ru) |
DE (1) | DE60237784D1 (ru) |
EA (1) | EA008536B1 (ru) |
ES (1) | ES2353379T3 (ru) |
IL (2) | IL161665A0 (ru) |
MX (1) | MXPA04004187A (ru) |
NO (1) | NO327101B1 (ru) |
NZ (1) | NZ532763A (ru) |
PL (1) | PL208388B1 (ru) |
UA (1) | UA80957C2 (ru) |
WO (1) | WO2003037366A1 (ru) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100501400C (zh) * | 2002-11-25 | 2009-06-17 | 希克龙制药公司 | 使用α胸腺素防护辐射损伤的方法 |
DK1613340T3 (da) | 2003-03-28 | 2010-08-30 | Sciclone Pharmaceuticals Inc | Behandling af aspergillus-infektioner med thymosin alfa 1 |
US8017129B2 (en) * | 2006-06-15 | 2011-09-13 | SciClone Pharmaceuticals International Ltd | Use of thymosin alpha 1 for preparing a medicament for the treatment of stage IV malignant melanoma |
US20080300166A1 (en) * | 2007-06-01 | 2008-12-04 | Sciclone Pharmaceuticals, Inc. | Treatment of Melanoma with Alpha Thymosin Peptides |
US20100317583A1 (en) * | 2007-12-14 | 2010-12-16 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa) |
US8716012B2 (en) | 2009-05-08 | 2014-05-06 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
WO2013134666A1 (en) * | 2012-03-08 | 2013-09-12 | Sciclone Pharmaceuticals, Inc. | Use of thymosin alpha for treatment of purulent rhinosinusitis |
US20130296223A1 (en) | 2012-03-30 | 2013-11-07 | Sciclone Pharmaceuticals, Inc. | Use of thymosin alpha for the treatment of sepsis |
SG11201702558VA (en) | 2014-10-21 | 2017-05-30 | Sciclone Pharmaceuticals Inc | Treatment of cancer with immune stimulators |
WO2016129005A1 (en) | 2015-02-09 | 2016-08-18 | Luigina Romani | Thymosin alpha 1 for use in treatment of cystic fibrosis |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447233A (en) * | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
US4444757A (en) * | 1981-11-16 | 1984-04-24 | Research Corporation | Use of thymosin as an anti-diabetes and anti-hypertensive disease agent |
TW224053B (ru) * | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
TW249754B (ru) * | 1993-10-26 | 1995-06-21 | Alpha I Biomedicals Inc | |
US5760000A (en) * | 1994-05-13 | 1998-06-02 | University Technologies International,Inc. | Inhibition of liver cancer by the use of GnRH and GnRH analogs |
US5888980A (en) * | 1994-06-30 | 1999-03-30 | Bio-Logic Research And Development Corporation | Compositions for enhancing immune function |
US5632983A (en) * | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
US5849596A (en) * | 1996-07-08 | 1998-12-15 | Food Industry Research And Development Institute | Process for determining the smoke content of edible oil |
AU2001277887B2 (en) * | 2000-07-14 | 2006-09-14 | Transform Pharmaceuticals, Inc. | System and method for optimizing tissue barrier transfer of compounds |
CA2427430A1 (en) * | 2000-11-02 | 2002-06-13 | Research Foundation Of City University Of New York | Methods for stimulating nervous system regeneration and repair by inhibition phosphodiesterase type 4 |
-
2002
- 2002-01-11 UA UA20040504064A patent/UA80957C2/uk unknown
- 2002-11-01 EA EA200400591A patent/EA008536B1/ru not_active IP Right Cessation
- 2002-11-01 NZ NZ532763A patent/NZ532763A/en not_active IP Right Cessation
- 2002-11-01 EP EP02802520A patent/EP1450850B1/en not_active Expired - Lifetime
- 2002-11-01 MX MXPA04004187A patent/MXPA04004187A/es active IP Right Grant
- 2002-11-01 ES ES02802520T patent/ES2353379T3/es not_active Expired - Lifetime
- 2002-11-01 DE DE60237784T patent/DE60237784D1/de not_active Expired - Lifetime
- 2002-11-01 AT AT02802520T patent/ATE481980T1/de not_active IP Right Cessation
- 2002-11-01 CN CNA02821871XA patent/CN1582163A/zh active Pending
- 2002-11-01 AU AU2002363248A patent/AU2002363248B2/en not_active Ceased
- 2002-11-01 US US10/493,848 patent/US20050049191A1/en not_active Abandoned
- 2002-11-01 BR BR0213823-9A patent/BR0213823A/pt not_active IP Right Cessation
- 2002-11-01 IL IL16166502A patent/IL161665A0/xx active IP Right Grant
- 2002-11-01 PL PL370430A patent/PL208388B1/pl not_active IP Right Cessation
- 2002-11-01 CA CA002464307A patent/CA2464307A1/en not_active Abandoned
- 2002-11-01 WO PCT/US2002/035093 patent/WO2003037366A1/en active Application Filing
- 2002-11-01 KR KR1020047006674A patent/KR20050042229A/ko not_active Ceased
- 2002-11-01 JP JP2003539708A patent/JP2005511563A/ja active Pending
-
2004
- 2004-04-29 IL IL161665A patent/IL161665A/en not_active IP Right Cessation
- 2004-05-21 NO NO20042100A patent/NO327101B1/no not_active IP Right Cessation
-
2010
- 2010-05-07 US US12/775,986 patent/US20100221274A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PL370430A1 (en) | 2005-05-30 |
US20050049191A1 (en) | 2005-03-03 |
ES2353379T3 (es) | 2011-03-01 |
PL208388B1 (pl) | 2011-04-29 |
BR0213823A (pt) | 2004-08-31 |
ATE481980T1 (de) | 2010-10-15 |
NO20042100D0 (no) | 2004-05-21 |
EP1450850A4 (en) | 2005-11-30 |
US20100221274A1 (en) | 2010-09-02 |
AU2002363248B2 (en) | 2007-11-22 |
WO2003037366A1 (en) | 2003-05-08 |
EP1450850A1 (en) | 2004-09-01 |
IL161665A0 (en) | 2004-09-27 |
MXPA04004187A (es) | 2004-07-08 |
DE60237784D1 (de) | 2010-11-04 |
CA2464307A1 (en) | 2003-05-08 |
EA008536B1 (ru) | 2007-06-29 |
NO327101B1 (no) | 2009-04-20 |
CN1582163A (zh) | 2005-02-16 |
IL161665A (en) | 2011-03-31 |
KR20050042229A (ko) | 2005-05-06 |
NZ532763A (en) | 2008-01-31 |
NO20042100L (no) | 2004-05-21 |
UA80957C2 (en) | 2007-11-26 |
JP2005511563A (ja) | 2005-04-28 |
EP1450850B1 (en) | 2010-09-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AZ BY KZ KG MD RU |