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EA200000552A1 - Готовые препаративные формы, содержащие растворенный пароксетин - Google Patents

Готовые препаративные формы, содержащие растворенный пароксетин

Info

Publication number
EA200000552A1
EA200000552A1 EA200000552A EA200000552A EA200000552A1 EA 200000552 A1 EA200000552 A1 EA 200000552A1 EA 200000552 A EA200000552 A EA 200000552A EA 200000552 A EA200000552 A EA 200000552A EA 200000552 A1 EA200000552 A1 EA 200000552A1
Authority
EA
Eurasian Patent Office
Prior art keywords
paroxetine
solid
paroxetin
ready
forms containing
Prior art date
Application number
EA200000552A
Other languages
English (en)
Inventor
Ахмад Газави
Грэхам Стэнли Леонард
Original Assignee
Смитклайн Бичам Плс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смитклайн Бичам Плс filed Critical Смитклайн Бичам Плс
Publication of EA200000552A1 publication Critical patent/EA200000552A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Предложена готовая фармацевтическая препаративная форма пароксетина, в которой пароксетин находится в растворе в твердом, полутвердом или жидком носителе. Эти растворы использованы для заполнения капсул, или самоподдерживающиеся твердые растворы сформованы в твердые дозированные формы, такие как таблетки или пилюли. Предложены также новые жидкие готовые препаративные формы, в которых использован солюбилизирующий агент для растворения пароксетина в маслах и/или липидах, и способы предотвращения использования других форм пароксетина, превращающихся в полугидраты, путем применения безводного или гидрофобного носителя или наполнителя.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200000552A 1997-11-21 1998-11-18 Готовые препаративные формы, содержащие растворенный пароксетин EA200000552A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation
PCT/GB1998/003471 WO1999026625A1 (en) 1997-11-21 1998-11-18 Formulations comprising dissolved paroxetine

Publications (1)

Publication Number Publication Date
EA200000552A1 true EA200000552A1 (ru) 2000-10-30

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000552A EA200000552A1 (ru) 1997-11-21 1998-11-18 Готовые препаративные формы, содержащие растворенный пароксетин

Country Status (24)

Country Link
EP (1) EP1033986A1 (ru)
JP (1) JP2001523718A (ru)
KR (1) KR20010032320A (ru)
CN (1) CN1279608A (ru)
AP (1) AP2000001821A0 (ru)
AR (1) AR015485A1 (ru)
AU (1) AU1168099A (ru)
BG (1) BG104527A (ru)
BR (1) BR9814220A (ru)
CO (1) CO4970832A1 (ru)
DZ (1) DZ2658A1 (ru)
EA (1) EA200000552A1 (ru)
GB (1) GB9724544D0 (ru)
HU (1) HUP0100580A3 (ru)
IL (1) IL136106A0 (ru)
MA (1) MA24704A1 (ru)
NO (1) NO20002590L (ru)
OA (1) OA11385A (ru)
PE (1) PE20000381A1 (ru)
PL (1) PL340555A1 (ru)
SK (1) SK7342000A3 (ru)
TR (1) TR200001423T2 (ru)
WO (1) WO1999026625A1 (ru)
ZA (1) ZA9810637B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
JP4854115B2 (ja) 1999-03-12 2012-01-18 エイシカ ファーマシューティカルス リミテッド 無水パロキセチン用安定製剤形
US6984632B1 (en) 1999-07-01 2006-01-10 Italfarmaco S.P.A. Complexes of paroxetine, with cyclodextrins or cyclodextrin derivatives
DE19930454A1 (de) * 1999-07-02 2001-01-04 Knoll Ag Feste Paroxetin enthaltende Zubereitungen
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
ATE374602T1 (de) * 2001-12-21 2007-10-15 Supernus Pharmaceuticals Inc Orale kapselformulierung mit verbesserter physikalischer stabilität
SE0200475D0 (sv) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral farmaceutisk beredning
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
US20120322752A1 (en) * 2009-12-08 2012-12-20 Sung Kyun Lee SOLID DISPERSIONS CONTAINING 20-O-beta-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (zh) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 甲磺酸帕罗西汀胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996031197A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
ID23250A (id) * 1997-01-15 2000-03-30 Smithkline Beecham Plc Komposisi paroksetin

Also Published As

Publication number Publication date
EP1033986A1 (en) 2000-09-13
KR20010032320A (ko) 2001-04-16
AR015485A1 (es) 2001-05-02
NO20002590D0 (no) 2000-05-19
MA24704A1 (fr) 1999-07-01
IL136106A0 (en) 2001-05-20
PE20000381A1 (es) 2000-05-07
JP2001523718A (ja) 2001-11-27
CN1279608A (zh) 2001-01-10
HUP0100580A3 (en) 2002-05-28
SK7342000A3 (en) 2000-12-11
GB9724544D0 (en) 1998-01-21
AP2000001821A0 (en) 2000-06-30
WO1999026625A1 (en) 1999-06-03
CO4970832A1 (es) 2000-11-07
PL340555A1 (en) 2001-02-12
HUP0100580A2 (hu) 2002-04-29
OA11385A (en) 2004-01-27
BR9814220A (pt) 2001-12-26
DZ2658A1 (fr) 2003-03-22
AU1168099A (en) 1999-06-15
BG104527A (en) 2001-04-30
TR200001423T2 (tr) 2000-10-23
ZA9810637B (en) 2000-05-22
NO20002590L (no) 2000-07-19

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