EA038946B1 - Analgesic and anti-inflammatory ointment against mastitis - Google Patents

Abstract

The invention relates to medicine and concerns agents for the treatment of infected skin wounds, burns, mastitis, arthritis, bruises, hemorrhoid. The essence of the invention consists in that an analgesic and anti-inflammatory ointment for mastitis comprises an oil extract based on medicinal plants - stinging nettle herb, barberry roots, quinquelobate motherwort herb, peppermint leaves, valerian roots - taken in equal amount. Olive oil is used as an extractant at a ratio of 1:10. The ointment also contains a supernatant of lymph nodes of femoral part of small cattle, obtained by centrifugation of said mashed lymph nodes at 2500-3000 rpm with a solution of 1.5 g of sodium chloride, and softened medical paraffin at the following ratio of components: oil extract of medicinal plants - 100 g; supernatant of lymph nodes - 20 g; softened medical paraffin - 70 g.

Description

The invention relates to medicine and relates to agents for the treatment of infected skin wounds, burns, mastitis, arthritis, bruises, hemorrhoids.

Mastitis is a real problem for many breastfeeding women. Streptococcus, staphylococcus and other bacteria cause disease, the pathological activity of which results in inflammation in the tissues and ducts of the mammary gland. These microorganisms penetrate into the female breast either through cracks in the nipples, which are often formed during lactation, or through the milk ducts. It is worth noting that mastitis can develop not only in lactating women, but also in pregnant women, as well as in women who are not expecting a baby (treatment of mastitis with folk remedies is found on the site).

Mastitis can occur in both acute and chronic forms. A woman who contracted mastitis initially presents symptoms of the disease similar to those of lactostasis. The mammary gland is visibly thickened, the skin turns red. The woman suffers from severe pain, her temperature rises greatly, and chills are observed.

As mastitis progresses, the breast becomes larger in size, it hurts to touch the skin on the mammary gland, it becomes hot to the touch. An abscess can develop directly in the thickness of the mammary gland with mastitis. It is very difficult for a woman with mastitis to breastfeed her baby; pus and blood can often be found in her milk (fhttp: //medside.ru/mastif).

Pain occurs spontaneously or with pressure, captures the entire gland or is localized in the area of seals, varies from minor discomfort to significant pain on palpation, can be painful, single or multiple, detected in one gland or in both. In the early stages, the disease manifests itself in breast enlargement and tenderness.

Often, discharge from the nipples is serous in nature, sometimes they resemble colostrum, greenish and bloody discharge is found (ibid.).

Antiseptic agents are known in the form of ointments containing a fatty product and a natural product that have analgesic and healing properties. For example, Konkov's ointment containing a bee product dissolved in a fatty product with the addition of a 15% aqueous solution of an antiseptic, which is used as ethacridine (see Dostoevsky P.P., Kornienko P.F., Vovk D.M., etc. Directory of veterinary drugs. - M .: Kolos, 1986, pp. 89-90).

The disadvantage of this ointment is its slow healing effect.

A high effect of attraction of mastitis is achieved with the help of drug complexes: methicillin plus kanamycin or oxacillin plus kanamycin. If anaerobic microorganisms are found in milk during the study, then lincomycin, clindamycin are included in the therapy. erythromycin, metronidazole (found on the Mastitis Treatment website).

However, the proposed drug complexes reduce the immune system of the woman in labor, which can worsen the condition of the child during feeding.

The objective of the invention is to select the components of the dosage form to increase the effectiveness of therapy for inflammation of the mammary gland, combining antimicrobial agents, natural plant components, solvents with the necessary antimicrobial, analgesic and anti-inflammatory effects, as well as expanding the arsenal of drugs for the treatment of mastitis. The essence of the invention lies in the fact that the analgesic and anti-inflammatory ointment for mastitis contains an oil extract based on medicinal plants - herb of stinging nettle, barberry roots, motherwort herb, peppermint leaves, valerian roots, taken in equal amounts. Olive oil is used as an extractant at a ratio of 1:10. The ointment also contains a supernatant of the lymph nodes of the femoral part of small ruminants, obtained by centrifuging the crushed said lymph nodes at 2500-3000 rpm with a solution of 1.5 g of sodium chloride, and softened medical paraffin with the following ratio of components, g: oil extract of medicinal plants - one hundred ; supernatant fluid of lymph nodes - 20; softened medical paraffin - 70.

The essence of the proposed ointment lies in the fact that the presence of an antigen, which plays the role of an immunomodulator, together with other ingredients, in a short time, relieves pain, swelling, redness, and palpation eliminates the compaction of the mammary glands.

The presence in the composition of specially selected herbal biologically active components, each of which has its own biochemical and physiological channel of directed action on the metabolism in the body through the skin, provides a broad beneficial effect of the means by the type of synergy and duplication of the necessary properties.

Consider the composition and purpose of the proposed medicinal plants:

Stinging nettle herb contains urticin glycoside, chlorophyll, carotenoids, tannins, vitamin C, pantothenic acid, it is used as an anti-inflammatory, antimicrobial, antihypoxant, diuretic, hemostatic, expectorant, analgesic, sweating, reparative, tonic desensitizing agent. Assembled creates a powerful alkaline environment and is used as a blood purifier,

- 1 038946 antioxidant, sedative, analgesic, anti-edema and allergy remedy. Increases hemoglobin in the blood and the number of red blood cells.

The roots of barberry contain malic, citric, tartaric acids, choline-like substances, mineral salts, vitamins C and E, and the alkaloid berberine. It is used as an anti-inflammatory, antispasmodic, sedative, hemostatic, analgesic, enveloping antiallergic agent.

The herb of motherwort five-lobed contains the alkaloid leonurin, aninstachydrin, flavonoids (quinqueloside, rutin, quercitrin, etc.), saponins, tannins, organic acids, carotene, essential oil, bitter substances are used as anti-inflammatory, antispasmodic, hypotensive, vasodilatory, fortifying, anticonvulsant pain reliever, decongestant.

Peppermint leaves contain essential oils, carotene, ascorbic acid, vitamin P, phytoncides, tannins, etc. Used as an anti-inflammatory, antimicrobial, antispasmodic, vasodilator, antihypertensive, sedative, hemostatic, analgesic, enveloping agent.

Valerian roots contain essential oil, alcohol ester borneolam isovaleric acid, formic acid, acetic acid, butyric acid, myrtenol, pinene, camphene, terpipsol, limonene and other terpenoids. It is used as an antispasmodic, vasodilator, hypotensive, sedative, analgesic anticonvulsant, sedative, analgesic, antineoplastic agent.

The ointment is prepared as follows.

1000 g of olive oil is heated to 50 ° C, after which finely rubbed leaves and roots taken in equal amounts are added to it, brought to a temperature of 90 ° C, cooled and kept for 5-10 hours. In parallel, 20 g of lymph nodes are cleaned of blood, cut into pieces and knead on glass wool. A solution of 1.5 g of sodium chloride is added to the resulting supernatant, and the resulting suspension is centrifuged for 9-10 minutes at 2500-3000 rpm, then 100 g of the obtained oil extract of medicinal plants is taken and the supernatant with sodium chloride is added to it with constant stirring.

The resulting oil part is added in small portions to the softened medical paraffin (70 g), mixing well until a homogeneous soft ointment is obtained.

The resulting yellowish-greenish ointment with a pleasant odor is easily absorbed into the skin and is used in the form of compresses to spread on the surface of the inflamed part of the body. The composition has an analgesic, tonic, anti-inflammatory effect.

The course of treatment is 5-10 sessions. In acute diseases, the course of treatment is increased to 20 days, if necessary, the course is repeated 2-3 times a year.

During treatment, one must adhere to a diet: exclude any smoked meats, alcohol, sugary drinks.

You can eat fruits and vegetables rich in fiber, vitamins and minerals that affect the gastrointestinal tract, it is recommended to drink plenty of fluids.

Along with the treatment of mastitis, the proposed ointment can be applied to the first stage of mastopathy, and this composition also dissolves gouty bumps on the arms and legs.

The proposed tool was tested in maternity hospital No. 5, Baku city.

Example 1.

Patient Suleimanova Zemfira, 32 years old, a few days after the birth of the child, on the 4th day, sharp pains appeared, followed by redness and induration of the right breast. Simultaneously high temperature up to 39 ° C, at night with severe chills. By the morning - torrential sweat, a decrease in body temperature to 36.5 °. Sharp weakness increased. The proposed ointment was prescribed, which was rubbed into the right mammary gland with gentle movements, then covered with a sterile napkin. Within 1 hour, the redness disappeared, the pain subsided. The procedure was repeated once more and the milk was expressed. The next day, the procedure was repeated, while feeding the baby was painless and calm.

Example 2.

Patient S. Akhmedova, born in 1975, consulted a doctor about severe pain, breast enlargement and redness before the menstrual cycle. It was proposed to use the claimed ointment. The patient rubbed it with gentle movements for 10 days in the morning and evening. The pain, redness and enlargement of the breasts gradually disappeared. Subsequent menstruation passed without chest pain.

Along with this, on the right hand from the elbow to the palm there were many small and three large gouty bumps, two weeks after rubbing the proposed ointment several times a day, small bumps disappeared, and the large ones decreased in volume. The treatment continues.

Thus, the proposed ointment, used for mastitis, allows you to relieve pain and inflammation in a short time, does not cause side effects.

Claims (1)

- 2 038946 CLAIM Anesthetic and anti-inflammatory ointment for mastitis, containing an oil extract based on medicinal plants - herb stinging nettle, barberry roots, motherwort herb, peppermint leaves, valerian roots, taken in equal amounts, as an extractant - olive oil at a ratio of 1:10, the supernatant fluid of the lymph nodes of the femoral part of small ruminants, obtained by centrifuging the crushed specified lymph nodes at 2500-3000 rpm with a solution of 1.5 g of sodium chloride, and softened medical paraffin with the following ratio of components, g: oil extract of medicinal plants - 100; supernatant fluid of lymph nodes - 20; softened medical paraffin - 70.