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DOP2015000245A - Derivados de 3-acetilamino-1 (fenil-heteroaril-aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos - Google Patents

Derivados de 3-acetilamino-1 (fenil-heteroaril-aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos

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Publication number
DOP2015000245A
DOP2015000245A DO2015000245A DO2015000245A DOP2015000245A DO P2015000245 A DOP2015000245 A DO P2015000245A DO 2015000245 A DO2015000245 A DO 2015000245A DO 2015000245 A DO2015000245 A DO 2015000245A DO P2015000245 A DOP2015000245 A DO P2015000245A
Authority
DO
Dominican Republic
Prior art keywords
heteroaril
phenyl
aminocarbonil
acetyllamin
carbonylamine
Prior art date
Application number
DO2015000245A
Other languages
English (en)
Inventor
Eckhard Bender
Kai Thede
William J Scott
Ludwig Zorn
Ningshu Liu
Ursula Mönning
Stefan Golz
Andrea Hägebarth
Philip Lineau
Florian Puehler
Dirk Schneider
Manfred Möwes
Daniel Basting
Franziska Siegel
Anja Richter
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of DOP2015000245A publication Critical patent/DOP2015000245A/es

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
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Abstract

LA PRESENTE INVENCIÓN SE RELACIONA CON N-(FENIL-HETEROARIL)-3-ACETILAMINO-BENZAMIDAS SUSTITUIDAS Y N-[3-(ACETILAMINO)FENIL]-FENIL-HETEROARIL-CARBOXAMIDAS DE FÓRMULA GENERAL (I) COMO SE DESCRIBE Y SE DEFINE EN LA PRESENTE, CON MÉTODOS DE PREPARACIÓN DE DICHOS COMPUESTOS, CON COMPUESTOS INTERMEDIARIOS ÚTILES PARA PREPARAR DICHOS COMPUESTOS, CON COMPOSICIONES FARMACÉUTICAS Y COMBINACIONES QUE COMPRENDEN DICHOS COMPUESTOS Y CON EL USO DE DICHOS COMPUESTOS PARA LA ELABORACIÓN DE UNA COMPOSICIÓN FARMACÉUTICA PARA EL TRATAMIENTO O PROFILAXIS DE UNA ENFERMEDAD.
DO2015000245A 2013-03-20 2015-09-18 Derivados de 3-acetilamino-1 (fenil-heteroaril-aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos DOP2015000245A (es)

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