DOP2003000797A - DOSAGE FORMS THAT INCLUDE A PTEC INHIBITOR AND A HMG-COA-REDUCTASA INHABITOR - Google Patents
DOSAGE FORMS THAT INCLUDE A PTEC INHIBITOR AND A HMG-COA-REDUCTASA INHABITORInfo
- Publication number
- DOP2003000797A DOP2003000797A DO2003000797A DO2003000797A DOP2003000797A DO P2003000797 A DOP2003000797 A DO P2003000797A DO 2003000797 A DO2003000797 A DO 2003000797A DO 2003000797 A DO2003000797 A DO 2003000797A DO P2003000797 A DOP2003000797 A DO P2003000797A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- hmg
- inhibitor
- coa
- inhabitor
- reductasa
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 4
- 239000003112 inhibitor Substances 0.000 title 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 3
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 abstract 1
- 229940125881 cholesteryl ester transfer protein inhibitor Drugs 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000007962 solid dispersion Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una forma de dosificacion comprende (1) una dispersion solida amorfa que comprende un inhibidor de la proteina de transferencia de osteres de colesterilo y un polimero acido potenciador de la concentracion, y (2) un inhibidor de la HMG-CoA-reductasa. La dispersion solida amorfa y el inhibidor de la HMG-CoA-reductasa se combinan en la forma de dosificacion de modo que la dispersion solida amorfa y el inhibidor de la HMG-CoA-reductasa estan sustancialmente separados entre si en la forma de dosificacion.A dosage form comprises (1) a solid amorphous dispersion comprising a cholesteryl ester transfer protein inhibitor and a concentration enhancing acid polymer, and (2) an HMG-CoA reductase inhibitor. The solid amorphous dispersion and the HMG-CoA reductase inhibitor are combined in the dosage form so that the amorphous solid dispersion and the HMG-CoA reductase inhibitor are substantially separated from each other in the dosage form.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DO2003000797A DOP2003000797A (en) | 2003-12-19 | 2003-12-19 | DOSAGE FORMS THAT INCLUDE A PTEC INHIBITOR AND A HMG-COA-REDUCTASA INHABITOR |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DO2003000797A DOP2003000797A (en) | 2003-12-19 | 2003-12-19 | DOSAGE FORMS THAT INCLUDE A PTEC INHIBITOR AND A HMG-COA-REDUCTASA INHABITOR |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2003000797A true DOP2003000797A (en) | 2004-10-30 |
Family
ID=44261282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2003000797A DOP2003000797A (en) | 2003-12-19 | 2003-12-19 | DOSAGE FORMS THAT INCLUDE A PTEC INHIBITOR AND A HMG-COA-REDUCTASA INHABITOR |
Country Status (1)
Country | Link |
---|---|
DO (1) | DOP2003000797A (en) |
-
2003
- 2003-12-19 DO DO2003000797A patent/DOP2003000797A/en unknown
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