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DK98692A - Monoklonalt antistof og fremgangsmaade til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og proeve for tumorcellefoelsomhed under anvendelse af det monoklonale antistof - Google Patents

Monoklonalt antistof og fremgangsmaade til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og proeve for tumorcellefoelsomhed under anvendelse af det monoklonale antistof Download PDF

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Publication number
DK98692A
DK98692A DK098692A DK98692A DK98692A DK 98692 A DK98692 A DK 98692A DK 098692 A DK098692 A DK 098692A DK 98692 A DK98692 A DK 98692A DK 98692 A DK98692 A DK 98692A
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DK
Denmark
Prior art keywords
monoclonal antibody
producing
tumor cell
cell sensitivity
sensitivity tests
Prior art date
Application number
DK098692A
Other languages
English (en)
Other versions
DK98692D0 (da
DK170423B1 (da
Inventor
Janet H Ransom
Richard P Mccabe
Martin V Haspel
Nicholas Pomato
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK98692D0 publication Critical patent/DK98692D0/da
Publication of DK98692A publication Critical patent/DK98692A/da
Application granted granted Critical
Publication of DK170423B1 publication Critical patent/DK170423B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK098692A 1984-04-13 1992-08-04 Monoklonalt antistof, der er specifikt for leukoregulincelleoverfladereceptorer, og fremgangsmåde til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og prøve for tumorcellefølsomhed under anvendelse af det monoklonale antistof DK170423B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60030384A 1984-04-13 1984-04-13
US60030384 1984-04-13

Publications (3)

Publication Number Publication Date
DK98692D0 DK98692D0 (da) 1992-08-04
DK98692A true DK98692A (da) 1992-08-04
DK170423B1 DK170423B1 (da) 1995-08-28

Family

ID=24403068

Family Applications (2)

Application Number Title Priority Date Filing Date
DK562285A DK170781B1 (da) 1984-04-13 1985-12-04 Human leukoregulin og biologisk aktive underenheder deraf, fremgangsmåde til fremstilling og til oprensning af human leukoregulin, biologisk aktivt materiale indeholdende human leukoregulin samt celle, som producerer human leukoregulin
DK098692A DK170423B1 (da) 1984-04-13 1992-08-04 Monoklonalt antistof, der er specifikt for leukoregulincelleoverfladereceptorer, og fremgangsmåde til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og prøve for tumorcellefølsomhed under anvendelse af det monoklonale antistof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK562285A DK170781B1 (da) 1984-04-13 1985-12-04 Human leukoregulin og biologisk aktive underenheder deraf, fremgangsmåde til fremstilling og til oprensning af human leukoregulin, biologisk aktivt materiale indeholdende human leukoregulin samt celle, som producerer human leukoregulin

Country Status (9)

Country Link
EP (1) EP0179127B1 (da)
JP (2) JP2562014B2 (da)
AT (1) ATE48617T1 (da)
AU (2) AU592529B2 (da)
DE (1) DE3574710D1 (da)
DK (2) DK170781B1 (da)
FI (1) FI85867C (da)
NO (1) NO170423C (da)
WO (1) WO1985004662A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU592529B2 (en) * 1984-04-13 1990-01-18 Litton Bionetics, Inc. Leukoregulin, an antitumor lymphokine, and its therapeutic uses
US5683688A (en) * 1984-05-31 1997-11-04 Genentech, Inc. Unglycosylated recombinant human lymphotoxin polypeptides and compositions
US6087166A (en) 1997-07-03 2000-07-11 Basf Aktiengesellschaft Transcriptional activators with graded transactivation potential
JP2009543544A (ja) 2006-05-15 2009-12-10 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法
WO2012156535A1 (en) 2011-05-19 2012-11-22 Fundación Progreso Y Salud Highly inducible dual-promoter lentiviral tet-on system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394448A (en) * 1978-02-24 1983-07-19 Szoka Jr Francis C Method of inserting DNA into living cells
US4403035A (en) * 1981-06-19 1983-09-06 Regents Of The University Of Minnesota In vitro DNA-Protein viral assembly and gene cloning system
DE3138230A1 (de) * 1981-09-25 1983-04-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verfahren zur gewinnung von makrophagen- aktivierungsfaktor (maf)
JPS6011889B2 (ja) * 1981-10-28 1985-03-28 電気化学工業株式会社 継代可能なリンホカイン産生ヒトｔ細胞融合株及びその取得方法
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
ZA834976B (en) * 1982-07-30 1984-08-29 Genentech Inc Human lymphotoxin
EP0135797A3 (de) * 1983-08-30 1987-11-11 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung von Lymphotoxin und von Lymphotoxin-mRNA
AU592529B2 (en) * 1984-04-13 1990-01-18 Litton Bionetics, Inc. Leukoregulin, an antitumor lymphokine, and its therapeutic uses

Also Published As

Publication number Publication date
AU4234185A (en) 1985-11-01
JP2562014B2 (ja) 1996-12-11
NO170423B (no) 1992-07-06
NO170423C (no) 1992-10-14
FI85867B (fi) 1992-02-28
EP0179127A1 (en) 1986-04-30
DK98692D0 (da) 1992-08-04
EP0179127A4 (en) 1986-08-21
DE3574710D1 (de) 1990-01-18
AU5365390A (en) 1990-09-20
WO1985004662A1 (en) 1985-10-24
AU592529B2 (en) 1990-01-18
DK170423B1 (da) 1995-08-28
JPH06253832A (ja) 1994-09-13
DK562285A (da) 1985-12-04
FI854803A0 (fi) 1985-12-04
FI85867C (fi) 1992-06-10
FI854803A (fi) 1985-12-04
ATE48617T1 (de) 1989-12-15
NO854994L (no) 1985-12-12
AU641386B2 (en) 1993-09-23
JP2564245B2 (ja) 1996-12-18
DK170781B1 (da) 1996-01-15
DK562285D0 (da) 1985-12-04
JPS61501853A (ja) 1986-08-28
EP0179127B1 (en) 1989-12-13

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed