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DK81579A - Phenoxyalkylcarbonsyrederivater fremgangsmaade til deres fremstilling samt laegemidler indeholdende disse forbindelser - Google Patents

Phenoxyalkylcarbonsyrederivater fremgangsmaade til deres fremstilling samt laegemidler indeholdende disse forbindelser

Info

Publication number
DK81579A
DK81579A DK81579A DK81579A DK81579A DK 81579 A DK81579 A DK 81579A DK 81579 A DK81579 A DK 81579A DK 81579 A DK81579 A DK 81579A DK 81579 A DK81579 A DK 81579A
Authority
DK
Denmark
Prior art keywords
phenoxyalcylcarbonic
procedures
compounds
preparation
acid derivatives
Prior art date
Application number
DK81579A
Other languages
English (en)
Other versions
DK164545C (da
DK164545B (da
Inventor
E C Witte
H P Wolff
M Thiel
K Stegmeier
E Roesch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK81579A publication Critical patent/DK81579A/da
Publication of DK164545B publication Critical patent/DK164545B/da
Application granted granted Critical
Publication of DK164545C publication Critical patent/DK164545C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK081579A 1978-03-04 1979-02-26 Analogifremgangsmaade til fremstilling af sulfonylamino- eller sulfonylaminoalkylphenoxyalkylcarbonsyrederivater eller fysiologisk uskadelige salte deraf DK164545C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2809377 1978-03-04
DE19782809377 DE2809377A1 (de) 1978-03-04 1978-03-04 Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
DK81579A true DK81579A (da) 1979-09-05
DK164545B DK164545B (da) 1992-07-13
DK164545C DK164545C (da) 1992-11-30

Family

ID=6033559

Family Applications (1)

Application Number Title Priority Date Filing Date
DK081579A DK164545C (da) 1978-03-04 1979-02-26 Analogifremgangsmaade til fremstilling af sulfonylamino- eller sulfonylaminoalkylphenoxyalkylcarbonsyrederivater eller fysiologisk uskadelige salte deraf

Country Status (20)

Country Link
US (1) US4258058A (da)
EP (1) EP0004011B1 (da)
JP (1) JPS54122250A (da)
AT (1) AT367745B (da)
AU (1) AU508419B2 (da)
CA (1) CA1136158A (da)
CS (3) CS208774B2 (da)
DD (1) DD142334A5 (da)
DE (2) DE2809377A1 (da)
DK (1) DK164545C (da)
ES (1) ES478228A1 (da)
FI (1) FI71305C (da)
HU (1) HU183085B (da)
IL (1) IL56734A0 (da)
NZ (1) NZ189776A (da)
PL (2) PL124924B1 (da)
PT (1) PT69295A (da)
SU (2) SU1052157A3 (da)
YU (2) YU42300B (da)
ZA (1) ZA79989B (da)

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DE3642105A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte aminomethyl-5,6,7,8-tetrahydronaphtyl-oxyessigsaeuren, neue zwischenprodukte, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
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US4752613A (en) * 1987-08-03 1988-06-21 E. R. Squibb & Sons, Inc. Sulphonamidothienylcarboxylic acid compounds
US4783473A (en) * 1987-09-02 1988-11-08 E. R. Squibb & Sons, Inc. Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use
US4931460A (en) * 1987-09-17 1990-06-05 E. R. Squibb & Sons, Inc. Post-ischemic myocardial dysfunction using thromboxane A2 antagonists
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JPH068275B2 (ja) * 1988-02-04 1994-02-02 田辺製薬株式会社 フェノキシ酢酸誘導体
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JPH01279826A (ja) * 1988-01-29 1989-11-10 Tanabe Seiyaku Co Ltd 血小板凝集抑制剤
US5066480A (en) * 1988-04-11 1991-11-19 E. R. Squibb & Sons, Inc. Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist
US4900723A (en) * 1988-04-29 1990-02-13 E. R. Squibb & Sons, Inc. Method of preventing or reducing venous thrombosis using a thromboxane A2 receptor antagonist in conjunction with heparin and combination
DE3819052A1 (de) * 1988-06-04 1989-12-07 Basf Ag Neue sulfonamid-derivate, ihre herstellung und verwendung
US4925873A (en) * 1988-09-01 1990-05-15 E. R. Squibb & Sons, Inc. Method of treating skin injuries using thromboxane A2 receptor antagonists
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5106991A (en) * 1989-06-02 1992-04-21 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US4975452A (en) * 1989-06-02 1990-12-04 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5025025A (en) * 1989-06-28 1991-06-18 Ciba-Geigy Corporation (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5264458A (en) * 1989-11-02 1993-11-23 Bayer Aktiengesellschaft Antithrombotic iso- and heterocyclic phenylsulphonamides
DE3942923A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeure-amide, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4006640A1 (de) * 1990-03-03 1991-09-05 Boehringer Mannheim Gmbh Phenylthioalkylcarbonsaeure-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4010536A1 (de) * 1990-04-02 1991-10-10 Boehringer Mannheim Gmbh Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure
US5189211A (en) * 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
DE4037174A1 (de) * 1990-11-22 1992-05-27 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE4041780A1 (de) * 1990-12-24 1992-06-25 Boehringer Mannheim Gmbh Neue amine, verfahren zu ihrer herstellung, sowie diese verbindungen enthaltende arzneimittel
JPH05125038A (ja) * 1991-03-07 1993-05-21 Tanabe Seiyaku Co Ltd フエノキシアルカン酸誘導体及びその製法
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
TW219358B (da) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
GB9220137D0 (en) * 1992-09-23 1992-11-04 Pfizer Ltd Therapeutic agents
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
AU2002234165A1 (en) 2000-11-03 2002-05-27 Tularik, Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
IL157540A0 (en) * 2001-02-28 2004-03-28 Univ Temple N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereof
EA008736B1 (ru) * 2002-02-28 2007-08-31 Темпл Юниверсити-Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Аминозамещенные (e)-2,6-диалкоксистирил-4-замещенные-бензилсульфоны для лечения пролиферативных расстройств
IL163608A0 (en) * 2002-02-28 2005-12-18 Univ Temple Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
FR2841550B1 (fr) * 2002-06-26 2007-05-04 Sederma Sa Nouvelles molecules derivees de la tyramine, leur mode de preparation, et leur utilisation seules ou associees dans des compositions cosmetiques ou dermopharmceutiques
US20060155269A1 (en) * 2005-01-12 2006-07-13 Prorhythm, Inc. Epicardial ablation using focused ultrasound
JP2007106697A (ja) * 2005-10-13 2007-04-26 Sederma Sa 新規なチラミン誘導体及びその製造方法、並びに該誘導体を含む化粧用組成物、若しくは皮膚用医薬組成物
US12161632B2 (en) 2014-05-16 2024-12-10 Cumberland Pharmaceuticals Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
EP3804717A1 (en) 2014-05-16 2021-04-14 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating systemic sclerosis or pulmonary arterial hypertension
BR112017027298A2 (pt) 2015-06-30 2018-09-04 Cumberland Pharmaceuticals, Inc. método de tratamento e/ou prevenção de drea ou asma em pacientes humanos; e método de prevenção, reversão ou tratamento de sintoma(s) de dessensibilização à aspirina em pacientes com drea
ES2955158T3 (es) 2016-05-11 2023-11-29 Cumberland Pharmaceuticals Inc Composiciones y métodos de tratamiento de la distrofia muscular con antagonistas del receptor de tromboxano-A2

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US3364249A (en) * 1964-01-30 1968-01-16 Merck & Co Inc N-carboxyalkyl-phenoxyalkanoic acid amide
US3402198A (en) * 1965-10-20 1968-09-17 William A. Bolhofer 2-(phenoxy), 2-(phenylthio) and 2-(anilino) substituted 2-alkylideneacetic acid derivatives
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US3629320A (en) * 1969-04-09 1971-12-21 Geigy Chem Corp 2-(4-halo- and 4-trifluoromethylphenylsulfonamido)phenylacetic acids and esters thereof
US3720709A (en) * 1969-12-16 1973-03-13 Merck & Co Inc Sulfonylphenoxyalkanoic acids
DE2149070C3 (de) * 1971-10-01 1978-03-23 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
DE2405622A1 (de) * 1974-02-06 1975-08-14 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben
DE2541342A1 (de) * 1975-09-17 1977-03-31 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben
US4112236A (en) * 1977-04-04 1978-09-05 Merck & Co., Inc. Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins

Also Published As

Publication number Publication date
DD142334A5 (de) 1980-06-18
ZA79989B (en) 1980-04-30
DK164545C (da) 1992-11-30
CA1136158A (en) 1982-11-23
NZ189776A (en) 1980-08-26
CS208776B2 (en) 1981-09-15
CS208774B2 (en) 1981-09-15
YU42300B (en) 1988-08-31
YU48179A (en) 1983-02-28
EP0004011B1 (de) 1981-04-01
EP0004011A1 (de) 1979-09-19
FI71305C (fi) 1986-12-19
ES478228A1 (es) 1979-05-16
PL223895A1 (da) 1981-05-22
HU183085B (en) 1984-04-28
AU508419B2 (en) 1980-03-20
AU4469379A (en) 1979-09-06
AT367745B (de) 1982-07-26
PL124924B1 (en) 1983-03-31
PT69295A (de) 1979-03-01
US4258058A (en) 1981-03-24
DK164545B (da) 1992-07-13
SU1052157A3 (ru) 1983-10-30
FI790727A (fi) 1979-09-05
DE2809377A1 (de) 1979-09-13
PL123364B1 (en) 1982-10-30
JPS54122250A (en) 1979-09-21
DE2960222D1 (en) 1981-04-23
JPS5735910B2 (da) 1982-07-31
PL213847A1 (da) 1980-12-01
IL56734A0 (en) 1979-05-31
FI71305B (fi) 1986-09-09
ATA161979A (de) 1981-12-15
CS208775B2 (en) 1981-09-15
YU98186A (en) 1986-10-31
SU1097194A3 (ru) 1984-06-07
YU42916B (en) 1988-12-31

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