DK79077A - Estere af androstadien-17-carboxylsyrer og fremgangsmade til fremstilling deraf - Google Patents

Estere af androstadien-17-carboxylsyrer og fremgangsmade til fremstilling deraf

Info

Publication number: DK79077A
Authority: DK; Denmark
Prior art keywords: androstadyen; esters; preparation; methods; carboxylic acids
Prior art date: 1976-02-24

Application number

DK79077A

Other languages

English (en)

Other versions

DK153493C (da

DK153493B (da

Inventor

J Kalvoda

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-02-24

Filing date

1977-02-23

Publication date

1977-08-25

1977-02-23 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1977-08-25 Publication of DK79077A publication Critical patent/DK79077A/da

1988-07-18 Publication of DK153493B publication Critical patent/DK153493B/da

1988-11-28 Application granted granted Critical

1988-11-28 Publication of DK153493C publication Critical patent/DK153493C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK079077A 1976-02-24 1977-02-23 Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden DK153493C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH225376A CH628355A5 (de)	1976-02-24	1976-02-24	Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
CH225376		1976-02-24

Publications (3)

Publication Number	Publication Date
DK79077A true DK79077A (da)	1977-08-25
DK153493B DK153493B (da)	1988-07-18
DK153493C DK153493C (da)	1988-11-28

Family

ID=4229445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK079077A DK153493C (da)	1976-02-24	1977-02-23	Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden

Country Status (26)

Country	Link
US (1)	US4285937A (da)
JP (1)	JPS52102264A (da)
AT (1)	AT361141B (da)
AU (1)	AU513559B2 (da)
BE (1)	BE851725A (da)
CA (1)	CA1084483A (da)
CH (4)	CH628355A5 (da)
CY (1)	CY1198A (da)
DD (1)	DD145918A5 (da)
DE (1)	DE2707336A1 (da)
DK (1)	DK153493C (da)
ES (5)	ES456134A1 (da)
FR (2)	FR2342302A1 (da)
GB (1)	GB1578243A (da)
HK (1)	HK57483A (da)
HU (1)	HU176762B (da)
IE (1)	IE45023B1 (da)
IL (2)	IL51519A (da)
KE (1)	KE3300A (da)
MX (1)	MX9203366A (da)
MY (1)	MY8500017A (da)
NL (1)	NL7701886A (da)
NZ (1)	NZ183418A (da)
SE (1)	SE436572B (da)
SG (1)	SG37383G (da)
ZA (1)	ZA771087B (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4188385A (en) *	1978-04-05	1980-02-12	Syntex (U.S.A.) Inc.	Thioetianic acid derivatives
PT69411A (en) *	1978-04-05	1979-04-01	Syntex Inc	4-halo etianic acids and derivatives thereof
US4198403A (en) *	1978-04-05	1980-04-15	Syntex (U.S.A.) Inc.	17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes
DE3024008C2 (de) *	1980-06-24	1982-04-15	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Herstellung von 17α-Hydroxy-etiocarbonsäuren
US4607028A (en) *	1983-08-18	1986-08-19	Ciba-Geigy Corporation	Novel carboxylic acid esters
SE8306370D0 (sv) *	1983-11-18	1983-11-18	Draco Ab	Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8501693D0 (sv) *	1985-04-04	1985-04-04	Draco Ab	Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
IL78144A0 (en) *	1985-04-04	1986-07-31	Draco Ab	Novel androstane-17beta-carboxylic acid esters
EP0477195A1 (en) *	1989-06-16	1992-04-01	The Upjohn Company	Suramin type compounds and angiostatic steroids to inhibit angiogenesis
US6596260B1 (en) *	1993-08-27	2003-07-22	Novartis Corporation	Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5646136A (en) *	1994-01-04	1997-07-08	Duke University	Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids
US5981517A (en) *	1996-05-09	1999-11-09	Soft Drugs, Inc.	Androstene derivatives
GB0015876D0 (en) *	2000-06-28	2000-08-23	Novartis Ag	Organic compounds
US6759398B2 (en)	2000-08-05	2004-07-06	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative
US6787532B2 (en) *	2000-08-05	2004-09-07	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivatives
GB0019172D0 (en) *	2000-08-05	2000-09-27	Glaxo Group Ltd	Novel compounds
US6777399B2 (en) *	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6750210B2 (en) *	2000-08-05	2004-06-15	Smithkline Beecham Corporation	Formulation containing novel anti-inflammatory androstane derivative
SK287576B6 (sk) *	2000-08-05	2011-03-04	Glaxo Group Limited	S-fluórmetylester kyseliny 6alfa, 9alfa-difluór-17alfa-[(2- furanylkarboxyl)oxy]-11beta-hydroxy-16alfa-metyl-3-oxo-androsta- 1,4-dién-17beta-karbotiovej, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom, jeho použitie a medziprodukty
US6777400B2 (en) *	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6858593B2 (en) *	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6858596B2 (en) *	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivative
UA77656C2 (en) *	2001-04-07	2007-01-15	Glaxo Group Ltd	S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
IL158222A0 (en) *	2001-04-30	2004-05-12	Glaxo Group Ltd	Anti-inflammatory 17. beta-carbothioate ester derivatives of androstane with a cyclic ester group in position 17. alpha
US20050175545A1 (en) *	2002-02-04	2005-08-11	Keith Biggadike	Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) *	2002-02-05	2002-03-20	Glaxo Wellcome Mfg Pte Ltd	Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en)	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
ATE369138T1 (de) *	2003-06-19	2007-08-15	Nicholas S Bodor	Verstärkung der aktivität und/oder wirkdauer von ausgewählten entzündungshemmenden steroiden
JP4893305B2 (ja) *	2003-06-19	2012-03-07	ボーダー、ニコラス・エス	局所又は他の局部投与用のソフト抗炎症性ステロイドの活性及び／又は作用持続性の増強
GB0507165D0 (en) *	2005-04-08	2005-05-18	Glaxo Group Ltd	Novel crystalline pharmaceutical product
WO2007045980A1 (en) *	2005-10-19	2007-04-26	Ranbaxy Laboratories Limited	Compositions of phosphodiesterase type iv inhibitors
US7687484B2 (en) *	2006-05-25	2010-03-30	Bodor Nicholas S	Transporter enhanced corticosteroid activity
US7691811B2 (en) *	2006-05-25	2010-04-06	Bodor Nicholas S	Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
GB0615108D0 (en) *	2006-07-28	2006-09-06	Glaxo Group Ltd	Novel formulations
US8227027B2 (en)	2007-12-07	2012-07-24	Presspart Gmbh & Co. Kg	Method for applying a polymer coating to an internal surface of a container
EP2111861A1 (en)	2008-04-21	2009-10-28	Ranbaxy Laboratories Limited	Compositions of phosphodiesterase type IV inhibitors
US8835410B2 (en)	2011-05-10	2014-09-16	Bodor Laboratories, Inc.	Treatment of eyelid dermatitis
CN111100176A (zh) *	2019-12-20	2020-05-05	重庆华邦胜凯制药有限公司	一种化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3636010A (en) *	1968-12-23	1972-01-18	Ciba Geigy Corp	Esters of steroid-17-carboxylic acids
GB1384372A (en) *	1971-01-20	1975-02-19	Glaxo Lab Ltd	Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) *	1972-07-19	1976-06-09	Glaxo Lab Ltd	17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) *	1974-08-30	1978-06-06	Glaxo Laboratories Limited	Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
GB1514476A (en) *	1974-08-30	1978-06-14	Glaxo Lab Ltd	Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates

1976
- 1976-02-24 CH CH225376A patent/CH628355A5/de not_active IP Right Cessation
1977
- 1977-02-18 CY CY1198A patent/CY1198A/xx unknown
- 1977-02-18 GB GB6955/77A patent/GB1578243A/en not_active Expired
- 1977-02-19 DE DE19772707336 patent/DE2707336A1/de active Granted
- 1977-02-22 DD DD77197502A patent/DD145918A5/de unknown
- 1977-02-22 IL IL51519A patent/IL51519A/xx unknown
- 1977-02-22 ES ES456134A patent/ES456134A1/es not_active Expired
- 1977-02-22 CA CA272,291A patent/CA1084483A/en not_active Expired
- 1977-02-22 NL NL7701886A patent/NL7701886A/xx unknown
- 1977-02-22 FR FR7705053A patent/FR2342302A1/fr active Granted
- 1977-02-23 BE BE175169A patent/BE851725A/xx not_active IP Right Cessation
- 1977-02-23 IE IE382/77A patent/IE45023B1/en not_active IP Right Cessation
- 1977-02-23 AT AT119477A patent/AT361141B/de not_active IP Right Cessation
- 1977-02-23 AU AU22572/77A patent/AU513559B2/en not_active Expired
- 1977-02-23 DK DK079077A patent/DK153493C/da not_active IP Right Cessation
- 1977-02-23 ZA ZA00771087A patent/ZA771087B/xx unknown
- 1977-02-23 SE SE7701999A patent/SE436572B/xx not_active IP Right Cessation
- 1977-02-23 HU HU77CI1720A patent/HU176762B/hu unknown
- 1977-02-23 NZ NZ183418A patent/NZ183418A/xx unknown
- 1977-02-24 JP JP1874377A patent/JPS52102264A/ja active Granted
1978
- 1978-01-27 FR FR7802324A patent/FR2369297A1/fr active Granted
- 1978-03-01 ES ES467433A patent/ES467433A1/es not_active Expired
- 1978-03-01 ES ES467434A patent/ES467434A1/es not_active Expired
- 1978-03-01 ES ES467430A patent/ES467430A1/es not_active Expired
- 1978-03-01 ES ES467432A patent/ES467432A1/es not_active Expired
1979
- 1979-10-30 US US06/089,677 patent/US4285937A/en not_active Expired - Lifetime
1980
- 1980-11-19 IL IL61512A patent/IL61512A0/xx unknown
1981
- 1981-06-11 CH CH383181A patent/CH629824A5/de not_active IP Right Cessation
- 1981-06-11 CH CH383381A patent/CH628641A5/de not_active IP Right Cessation
- 1981-06-11 CH CH383281A patent/CH628356A5/de not_active IP Right Cessation
1983
- 1983-06-23 KE KE3300A patent/KE3300A/xx unknown
- 1983-06-27 SG SG373/83A patent/SG37383G/en unknown
- 1983-11-17 HK HK574/83A patent/HK57483A/xx unknown
1985
- 1985-12-30 MY MY17/85A patent/MY8500017A/xx unknown
1992
- 1992-06-25 MX MX9203366A patent/MX9203366A/es unknown

Also Published As

Publication number	Publication date
KE3300A (en)	1983-08-05
SE7701999L (sv)	1977-08-25
FR2342302B1 (da)	1981-01-09
CY1198A (en)	1983-12-31
JPS52102264A (en)	1977-08-27
HK57483A (en)	1983-11-25
SE436572B (sv)	1985-01-07
ES467432A1 (es)	1979-08-16
ES456134A1 (es)	1978-05-01
FR2342302A1 (fr)	1977-09-23
FR2369297A1 (fr)	1978-05-26
AU2257277A (en)	1978-08-31
ATA119477A (de)	1980-07-15
DD145918A5 (de)	1981-01-14
ES467430A1 (es)	1979-08-16
US4285937A (en)	1981-08-25
DE2707336A1 (de)	1977-08-25
IE45023L (en)	1977-08-24
HU176762B (en)	1981-05-28
IL51519A0 (en)	1977-04-29
ES467434A1 (es)	1979-08-16
FR2369297B1 (da)	1981-03-06
NZ183418A (en)	1980-02-21
DK153493C (da)	1988-11-28
CH629824A5 (de)	1982-05-14
CH628641A5 (de)	1982-03-15
IL61512A0 (en)	1980-12-31
JPS6139959B2 (da)	1986-09-06
BE851725A (fr)	1977-08-23
CA1084483A (en)	1980-08-26
DK153493B (da)	1988-07-18
AT361141B (de)	1981-02-25
CH628356A5 (de)	1982-02-26
ES467433A1 (es)	1979-10-16
CH628355A5 (de)	1982-02-26
GB1578243A (en)	1980-11-05
ZA771087B (en)	1978-01-25
AU513559B2 (en)	1980-12-11
IE45023B1 (en)	1982-06-02
IL51519A (en)	1983-03-31
MY8500017A (en)	1985-12-31
NL7701886A (nl)	1977-08-26
SG37383G (en)	1984-02-17
DE2707336C2 (da)	1988-09-01
MX9203366A (es)	1992-09-01

Publication	Publication Date	Title
DK79077A (da)	1977-08-25	Estere af androstadien-17-carboxylsyrer og fremgangsmade til fremstilling deraf
DK248078A (da)	1978-12-04	Phatalaziner og fremgangsmaade til fremstilling deraf
DK137378A (da)	1978-10-01	Taeppe og fremgangsmaade til fremstilling deraf
DK454178A (da)	1979-04-13	Acylanilider og fremgangsmaade til fremstilling deraf
DK102177A (da)	1977-09-10	Aminoalkyl-heterocycliske forbindelser og fremgangsmade til fremstilling deraf
DK575776A (da)	1977-07-21	Fremgangsmade til fremstilling af estere og amider af pyrimido(4,5-b)quinolin-4-(3h)-on-2-carboxylsyrer
DK538277A (da)	1978-06-04	Derivater af thiazolidinacarboxylsyrer og dermed beslaegtede syrer
DK251677A (da)	1977-12-10	N-phosphonomethylen-monoaminoalkanmono- og-polyphosphonsyrer og n-phosphomethylendiaminoalkan-polyphosphonsyrer samt fremgangsmade til fremstilling deraf
DK335876A (da)	1977-01-25	3-oximer af d-17alfa-ethynyl-19-nortestosteronestere og fremgangsmade til fremstilling deraf
DK502977A (da)	1978-05-17	Antracyklinderivat og fremgangsmaade til fremstilling deraf
DK102278A (da)	1978-09-10	Fremgangsmaade til fremstilling af dihalogenvinyl-cyclopropancarboxylsyrer og deres estere
DK96177A (da)	1977-09-06	4-androsten-3-oner og fremgangsmade til fremstilling heraf
DK370277A (da)	1978-02-21	Didhydro-oxo-nikotinsyrer og fremgangsmaade til fremstilling deraf
DK121776A (da)	1976-09-23	Fremgangsmade til fremstilling af tricosen-(9) og heneicosen-(9)
DK12478A (da)	1978-07-13	Dithienylalkylaminer og fremgangsmaade til fremstilling deraf
DK413578A (da)	1979-03-22	Isoquinolinderivater og fremgangsmaade til fremstilling deraf
DK475878A (da)	1979-04-28	Estere af alfa-halogenerede alkoholer og fremgangsmaade til fremstilling deraf
DK240678A (da)	1978-12-02	Fremgangsmaade til fremstilling af di og trifluormethylaminosyrer
DK224279A (da)	1979-12-01	Polyjodbenzenderivater og fremgangsmaade til fremstilling deraf
DK352276A (da)	1977-02-06	Immunologiske adjuvanser og fremgangsmade til fremstilling deraf
DK142238C (da)	1981-02-23	Vinylthionophosphorsyreestere med insecticid og acaricid virkning
DK562177A (da)	1978-06-17	Estere af phenylethylaminer og fremgangsmaade til fremstilling heraf
DK218676A (da)	1976-11-20	Blandinger af polyforgrenede mono-carboxylsyrer og fremgangsmade til fremstilling heraf
DK213878A (da)	1978-11-17	17beta-hydroxy-4-androsten-3-on og fremgangsmaade til fremstilling heraf
DK348176A (da)	1977-02-10	Fremgangsmade til fremstilling af tverbindelige polymerisater og copolymerisater

Legal Events

Date	Code	Title
1988-07-04	AHS	Application shelved for other reasons than non-payment
1991-01-21	AHB	Application shelved due to non-payment
1997-04-01	PUP	Patent expired