DK673788A - Immobiliseret interleukin-2 og interleukin-2 med carboxy-terminal forlaengelse - Google Patents

Immobiliseret interleukin-2 og interleukin-2 med carboxy-terminal forlaengelse

Info

Publication number: DK673788A
Authority: DK; Denmark
Prior art keywords: interleukin; immobilized; carboxy terminal; terminal extension; extension
Prior art date: 1987-12-04

Application number

DK673788A

Other languages

English (en)

Other versions

DK673788D0 (da

Inventor

Yuan Lin De Vries

Richard John Robb

Paul Simon

Charles Thayer White

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-04

Filing date

1988-12-02

Publication date

1989-06-05

1988-12-02 Application filed by Du Pont filed Critical Du Pont

1988-12-02 Publication of DK673788D0 publication Critical patent/DK673788D0/da

1989-06-05 Publication of DK673788A publication Critical patent/DK673788A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
Cell Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Wood Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Developmental Biology & Embryology (AREA)
General Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK673788A 1987-12-04 1988-12-02 Immobiliseret interleukin-2 og interleukin-2 med carboxy-terminal forlaengelse DK673788A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12893187A	1987-12-04	1987-12-04

Publications (2)

Publication Number	Publication Date
DK673788D0 DK673788D0 (da)	1988-12-02
DK673788A true DK673788A (da)	1989-06-05

Family

ID=22437677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK673788A DK673788A (da)	1987-12-04	1988-12-02	Immobiliseret interleukin-2 og interleukin-2 med carboxy-terminal forlaengelse

Country Status (11)

Country	Link
EP (1)	EP0319012A3 (da)
JP (1)	JPH02300A (da)
KR (1)	KR890009978A (da)
AU (1)	AU2635088A (da)
DK (1)	DK673788A (da)
FI (1)	FI885628A (da)
HU (1)	HUT50506A (da)
IL (1)	IL88565A0 (da)
NO (1)	NO885389L (da)
PT (1)	PT89121A (da)
ZA (1)	ZA888978B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5229272A (en) *	1989-04-25	1993-07-20	Igen, Inc.	Catalytic antibody components
EP0460101A4 (en) *	1989-02-24	1992-04-15	Immunotherapeutics, Inc.	Immobilized cytokines
US5547839A (en)	1989-06-07	1996-08-20	Affymax Technologies N.V.	Sequencing of surface immobilized polymers utilizing microflourescence detection
US5143854A (en) *	1989-06-07	1992-09-01	Affymax Technologies N.V.	Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
EP0406857B1 (en) *	1989-07-07	1995-05-24	Takeda Chemical Industries, Ltd.	Proteins and production thereof
FR2653020B1 (fr) *	1989-10-17	1993-03-26	Roussel Uclaf	Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour la preparation de compositions pharmaceutiques destinees au traitement des leucemies.
AU657910B2 (en) *	1990-07-05	1995-03-30	Akzo N.V.	Receptor directed-toxin conjugates
FR2666898A1 (fr) *	1990-09-18	1992-03-20	Toledano Jacques	Dispositif et procede de dosage rapide de recepteurs membranaires ou de leurs ligands.
US6072039A (en) *	1991-04-19	2000-06-06	Rohm And Haas Company	Hybrid polypeptide comparing a biotinylated avidin binding polypeptide fused to a polypeptide of interest
US5635597A (en) *	1994-05-27	1997-06-03	Affymax Technologies, N.V.	Peptides that bind IL-2 receptors
FR2764988B1 (fr) *	1997-06-20	1999-07-23	Bio Merieux	Compose conjugue, reactif et kit le contenant, et utilisations dans un procede de fixation d'un materiel biologique
CA2693296C (en)	1997-12-08	2013-09-10	Merck Patent Gmbh	Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
SK782002A3 (en)	1999-07-21	2003-08-05	Lexigen Pharm Corp	FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
RU2263118C2 (ru)	1999-08-09	2005-10-27	Лексиген Фармасьютикэлс Корп.	Комплексы антител с несколькими цитокинами
CA2399832C (en)	2000-02-11	2011-09-20	Stephen D. Gillies	Enhancing the circulating half-life of antibody-based fusion proteins
EP1366067B1 (en)	2001-03-07	2012-09-26	Merck Patent GmbH	Expression technology for proteins containing a hybrid isotype antibody moiety
WO2002079415A2 (en)	2001-03-30	2002-10-10	Lexigen Pharmaceuticals Corp.	Reducing the immunogenicity of fusion proteins
CN100503639C (zh)	2001-05-03	2009-06-24	默克专利有限公司	重组肿瘤特异性抗体及其应用
FR2832508A1 (fr) *	2001-11-21	2003-05-23	Bio Merieux	Procede d'obtention d'une phase de capture et d'une phase de detection d'un materiel biologique cible et utilisation dans des tests elisa
EP2354791A1 (en)	2001-12-04	2011-08-10	Merck Patent GmbH	Immunocytokines with modulated selectivity
AU2003298187B2 (en)	2002-12-17	2010-09-16	Merck Patent Gmbh	Humanized antibody (H14.18) of the mouse 14.18 antibody binding to GD2 and its fusion with IL-2
PT2573166T (pt)	2004-02-26	2016-07-07	Immunovative Therapies Ltd	Métodos para preparar células-t para terapia celular
US7592431B2 (en) *	2004-02-26	2009-09-22	Immunovative Therapies, Ltd.	Biodegradable T-cell Activation device
CN100391726C (zh) *	2006-04-28	2008-06-04	江阴市万事达液压机械有限公司	缸体破碎机
KR20120093002A (ko) *	2011-02-14	2012-08-22	(주)에이티젠	Ｎｋ 세포의 활성 측정을 이용한 암 진단 방법 및 진단 키트
AU2012250794B2 (en)	2011-05-03	2015-11-05	Immunovative Therapies, Ltd.	Methods for handling biological drugs containing living cells
AU2012250807A1 (en)	2011-05-03	2013-12-12	Immunovative Therapies, Ltd.	Induction of IL-12 using immunotherapy
JP2021533183A (ja) *	2018-07-13	2021-12-02	アイエル−２アールエックスインコーポレイテッド	がんおよび免疫障害を治療するための化合物、組成物、方法および使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1985000817A1 (en) *	1983-08-10	1985-02-28	Amgen	Microbial expression of interleukin ii
US4703004A (en) *	1984-01-24	1987-10-27	Immunex Corporation	Synthesis of protein with an identification peptide
JPS6153300A (ja) *	1984-08-23	1986-03-17	Takeda Chem Ind Ltd	固定化インタ−ロイキン−２
JPS61277628A (ja) *	1985-06-04	1986-12-08	Asahi Chem Ind Co Ltd	癌治療用白血球刺激材

1988
- 1988-11-30 ZA ZA888978A patent/ZA888978B/xx unknown
- 1988-11-30 AU AU26350/88A patent/AU2635088A/en not_active Abandoned
- 1988-11-30 PT PT89121A patent/PT89121A/pt not_active Application Discontinuation
- 1988-12-02 EP EP88120114A patent/EP0319012A3/en not_active Withdrawn
- 1988-12-02 JP JP63304265A patent/JPH02300A/ja active Pending
- 1988-12-02 FI FI885628A patent/FI885628A/fi not_active Application Discontinuation
- 1988-12-02 DK DK673788A patent/DK673788A/da not_active Application Discontinuation
- 1988-12-02 HU HU886164A patent/HUT50506A/hu unknown
- 1988-12-02 NO NO88885389A patent/NO885389L/no unknown
- 1988-12-02 IL IL88565A patent/IL88565A0/xx unknown
- 1988-12-03 KR KR1019880016106A patent/KR890009978A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL88565A0 (en)	1989-07-31
FI885628A (fi)	1989-06-05
NO885389L (no)	1989-06-05
ZA888978B (en)	1990-07-25
EP0319012A3 (en)	1990-05-16
FI885628A0 (fi)	1988-12-02
JPH02300A (ja)	1990-01-05
KR890009978A (ko)	1989-08-05
AU2635088A (en)	1989-06-08
EP0319012A2 (en)	1989-06-07
HUT50506A (en)	1990-02-28
NO885389D0 (no)	1988-12-02
PT89121A (pt)	1989-12-29
DK673788D0 (da)	1988-12-02

Publication	Publication Date	Title
DK673788A (da)	1989-06-05	Immobiliseret interleukin-2 og interleukin-2 med carboxy-terminal forlaengelse
DK399387D0 (da)	1987-07-31	Immobiliseret lipase og dennes anvendelse
DK80591A (da)	1991-04-30	Retningsboreapparat og fremgangsmaade
NO864590D0 (no)	1986-11-18	Kryogensk og ultrasonisk skalpell.
DK291186A (da)	1986-12-21	Antianafylaktiske og antibronchospastiske n-benzhydryldiazacykloalkylalkananilider
NO870065D0 (no)	1987-01-07	Piezoelektrisk belastningshus og fremgangsmaate.
NO883082D0 (no)	1988-07-08	Substituerte alkenkarboksylsyreamider og derivater.
DK450688A (da)	1989-02-13	Konditioneringsmidler og fremstilling deraf
DK413187D0 (da)	1987-08-07	Semicarbazoner og thiosemicarbazoner
DK451786A (da)	1987-03-24	Transglucosidase, fremstilling og anvendelse deraf
DK196088D0 (da)	1988-04-11	Rekombinant htlv-iii protein og anvendelse deraf
NO862343D0 (no)	1986-06-11	Elektrolysoer med diafragma-elektrode-sandwichanordning og herfor egnet montasje-innretning.
DK402888D0 (da)	1988-07-19	Antistoffer mod c5a og anvendelse deraf
DK521182A (da)	1983-05-27	Elektrisk kontakt med snapvirkende aktivator og udloeselige holde-organer
NO863469D0 (no)	1986-08-29	Herbicid og fremgangsmaate for anvendelse derav.
DK479989A (da)	1989-09-29	Carbonhydridemulsion og anvendelse deraf
DK363786D0 (da)	1986-07-30	Hydroquinoliner og anvendelse deraf
KR890012869U (ko)	1989-08-08	단관 및 엘보우 취부용 바이스
DK90087D0 (da)	1987-02-23	Stillads og stilladsbuk dertil
IL86486A0 (en)	1988-11-15	Avian interleukin-2
DK631987A (da)	1989-06-02	Daasemultipakning og multipakningsindretning
DK577388D0 (da)	1988-10-17	Humant interleukin -3 og muteiner deraf
DK684187D0 (da)	1987-12-23	Flecainidderivat og anvendelse deraf
KR890009912U (ko)	1989-05-31	리드-프레임 터미날과 세라믹 조립 장치
DK175187A (da)	1988-09-20	Kombineret afbryder og komponentholder

Legal Events

Date	Code	Title	Description
1993-08-30	AHB	Application shelved due to non-payment