DK671588A - Bisphenylalkylpiperazinderivater og fremgangsmaade til fremstilling deraf - Google Patents

Bisphenylalkylpiperazinderivater og fremgangsmaade til fremstilling deraf

Info

Publication number: DK671588A
Authority: DK; Denmark
Prior art keywords: hydrogen; lower alkyl; different; halogen; image
Prior art date: 1987-04-02

Application number

DK671588A

Other languages

English (en)

Other versions

DK161313C (da

DK161313B (da

DK671588D0 (da

Inventor

Tomas Fex

Knut Gunnar Olsson

Aina Lisbeth Abramo

Erik Gunnar Christensson

Torbjoern Erik Lundstedt

Original Assignee

Leo Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-02

Filing date

1988-12-01

Publication date

1988-12-01

1988-12-01 Application filed by Leo Ab filed Critical Leo Ab

1988-12-01 Publication of DK671588D0 publication Critical patent/DK671588D0/da

1988-12-01 Publication of DK671588A publication Critical patent/DK671588A/da

1991-06-24 Publication of DK161313B publication Critical patent/DK161313B/da

1991-12-30 Application granted granted Critical

1991-12-30 Publication of DK161313C publication Critical patent/DK161313C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK671588A 1987-04-02 1988-12-01 4-(bis-fluorphenylbutyl)-1-(pyridyl- eller pyrimidinyl)-piperazin- eller -1,4-diazabicycloheptanforbindelser, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende disse samt anvendelse af forbindelserne DK161313C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8701375A SE8701375D0 (sv)	1987-04-02	1987-04-02	Novel pyridyl- and pyrimidyl derivatives
SE8701375		1987-04-02
SE8800144		1988-01-18
PCT/SE1988/000144 WO1988007528A1 (en)	1987-04-02	1988-03-25	Bisphenylalkylpiperazine derivatives, a method of their preparation and a pharmaceutical preparation

Publications (4)

Publication Number	Publication Date
DK671588D0 DK671588D0 (da)	1988-12-01
DK671588A true DK671588A (da)	1988-12-01
DK161313B DK161313B (da)	1991-06-24
DK161313C DK161313C (da)	1991-12-30

Family

ID=20368077

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK671588A DK161313C (da)	1987-04-02	1988-12-01	4-(bis-fluorphenylbutyl)-1-(pyridyl- eller pyrimidinyl)-piperazin- eller -1,4-diazabicycloheptanforbindelser, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende disse samt anvendelse af forbindelserne

Country Status (18)

Country	Link
US (1)	US4937245A (da)
EP (1)	EP0308476B1 (da)
JP (1)	JPH0819104B2 (da)
KR (1)	KR920003062B1 (da)
AT (1)	ATE85334T1 (da)
AU (1)	AU611147B2 (da)
CA (1)	CA1321997C (da)
DE (1)	DE3878111T2 (da)
DK (1)	DK161313C (da)
ES (1)	ES2006619A6 (da)
FI (1)	FI92320C (da)
HU (1)	HU201051B (da)
IE (1)	IE61165B1 (da)
IL (1)	IL85932A (da)
NO (1)	NO172640C (da)
NZ (1)	NZ224005A (da)
SE (1)	SE8701375D0 (da)
WO (1)	WO1988007528A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8701375D0 (sv) *	1987-04-02	1987-04-02	Leo Ab	Novel pyridyl- and pyrimidyl derivatives
US5219855A (en) *	1988-01-29	1993-06-15	Mitsubishi Kasei Corporation	Anxiolytic drug
JP2664238B2 (ja) *	1989-03-01	1997-10-15	日清製粉株式会社	ニコチン酸またはそのエステル誘導体
US4994460A (en) *	1989-06-01	1991-02-19	Bristol-Myers Squibb Co.	Agents for treatment of brain ischemia
SE9201239D0 (sv) *	1992-04-21	1992-04-21	Kabi Pharmacia Ab	Agents for treating substance abuse disorders
EP0580465A1 (fr) *	1992-06-25	1994-01-26	Sanofi	Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
SE9201956D0 (sv) *	1992-06-25	1992-06-25	Kabi Pharmacia Ab	Novel nicotinicacid esters
JPH0665203A (ja) *	1992-06-25	1994-03-08	Elf Sanofi	ピペラジンのヘテロ環誘導体
SE9202265D0 (sv) *	1992-07-31	1992-07-31	Kabi Pharmacia Ab	Novel- pyridyl and pyrimidylpiperazine derivatives
BR9813279B1 (pt)	1997-10-27	2010-11-16		derivado de homopiperazina, composição farmacêutica, e, uso do derivado de homopiperazina.
US6632823B1 (en) *	1997-12-22	2003-10-14	Merck & Co., Inc.	Substituted pyridine compounds useful as modulators of acetylcholine receptors
KR20020005662A (ko)	1999-04-09	2002-01-17	기따자또 이찌로	질소함유 복소환화합물 및 벤즈아미드화합물 및 그 것을함유해서 되는 의약

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2958694A (en) *	1959-06-22	1960-11-01	Janssen Paul Adriaan Jan	1-(aroylalkyl)-4-(2'-pyridyl) piperazines
US2979508A (en) *	1959-10-12	1961-04-11	Paul A J Janssen	Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
US2985657A (en) *	1959-10-12	1961-05-23	Paul A J Janssen	1-(aroylalkyl)-4-heterocyclylpiperazines
JPS6081167A (ja) *	1983-10-11	1985-05-09	Sumitomo Chem Co Ltd	フエニルアセトン誘導体およびその製造法
US4605655A (en) *	1984-03-06	1986-08-12	Bristol-Myers Company	Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
JPS6175A (ja) *	1984-03-06	1986-01-06	ブリストル−マイア−ズ　コムパニ−	神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
GB8603120D0 (en) *	1986-02-07	1986-03-12	Pfizer Ltd	Anti-dysrhythmia agents
JPS63146872A (ja) *	1986-07-08	1988-06-18	Yoshitomi Pharmaceut Ind Ltd	ピリミジニルピペラジン化合物
US4766215A (en) *	1987-02-27	1988-08-23	American Home Products Corporation	Histamine H1 -receptor antagonists
SE8701375D0 (sv) *	1987-04-02	1987-04-02	Leo Ab	Novel pyridyl- and pyrimidyl derivatives

1987
- 1987-04-02 SE SE8701375A patent/SE8701375D0/xx unknown
1988
- 1988-03-23 IE IE86988A patent/IE61165B1/en not_active IP Right Cessation
- 1988-03-24 NZ NZ224005A patent/NZ224005A/en unknown
- 1988-03-25 HU HU882510A patent/HU201051B/hu not_active IP Right Cessation
- 1988-03-25 WO PCT/SE1988/000144 patent/WO1988007528A1/en active IP Right Grant
- 1988-03-25 DE DE8888903427T patent/DE3878111T2/de not_active Expired - Fee Related
- 1988-03-25 AU AU15796/88A patent/AU611147B2/en not_active Ceased
- 1988-03-25 AT AT88903427T patent/ATE85334T1/de not_active IP Right Cessation
- 1988-03-25 JP JP63503107A patent/JPH0819104B2/ja not_active Expired - Fee Related
- 1988-03-25 US US07/282,130 patent/US4937245A/en not_active Expired - Lifetime
- 1988-03-25 EP EP88903427A patent/EP0308476B1/en not_active Expired - Lifetime
- 1988-03-30 IL IL85932A patent/IL85932A/xx not_active IP Right Cessation
- 1988-03-30 ES ES8800998A patent/ES2006619A6/es not_active Expired
- 1988-03-31 CA CA000563050A patent/CA1321997C/en not_active Expired - Fee Related
- 1988-04-02 KR KR1019880003734A patent/KR920003062B1/ko not_active IP Right Cessation
- 1988-11-30 FI FI885560A patent/FI92320C/fi not_active IP Right Cessation
- 1988-12-01 DK DK671588A patent/DK161313C/da not_active IP Right Cessation
- 1988-12-02 NO NO885386A patent/NO172640C/no unknown

Also Published As

Publication number	Publication date
HUT50325A (en)	1990-01-29
DE3878111T2 (de)	1993-07-01
ATE85334T1 (de)	1993-02-15
WO1988007528A1 (en)	1988-10-06
DK161313C (da)	1991-12-30
HU201051B (en)	1990-09-28
ES2006619A6 (es)	1989-05-01
KR920003062B1 (ko)	1992-04-13
AU1579688A (en)	1988-11-02
JPH01502832A (ja)	1989-09-28
DK161313B (da)	1991-06-24
IE61165B1 (en)	1994-10-05
KR880012586A (ko)	1988-11-28
FI92320B (fi)	1994-07-15
NO172640C (no)	1993-08-18
IL85932A0 (en)	1988-09-30
AU611147B2 (en)	1991-06-06
FI92320C (fi)	1994-10-25
IL85932A (en)	1993-05-13
US4937245A (en)	1990-06-26
FI885560A0 (fi)	1988-11-30
JPH0819104B2 (ja)	1996-02-28
NO885386L (no)	1988-12-02
DK671588D0 (da)	1988-12-01
EP0308476B1 (en)	1993-02-03
NO885386D0 (no)	1988-12-02
NZ224005A (en)	1991-03-26
SE8701375D0 (sv)	1987-04-02
IE880869L (en)	1988-10-02
CA1321997C (en)	1993-09-07
NO172640B (no)	1993-05-10
EP0308476A1 (en)	1989-03-29
DE3878111D1 (de)	1993-03-18
FI885560A (fi)	1988-11-30

Publication	Publication Date	Title
DK148392D0 (da)	1992-12-09	Heterocykliske forbindelser
DK671588A (da)	1988-12-01	Bisphenylalkylpiperazinderivater og fremgangsmaade til fremstilling deraf
ES8706165A1 (es)	1987-06-01	Un procedimiento para la preparacion de derivados de androstendiona 4-sustituida.
NO163855C (no)	1990-08-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive arylcyklobutylalkylaminer.
NO179707C (no)	1996-12-04	Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer
DK380680A (da)	1981-03-08	Fremgangsmaade til fremstilling af substituerede oxirancarboxylsyrer
ATE22891T1 (de)	1986-11-15	Pyrimidinonderivate und diese enthaltende pharmazeutische zusammensetzungen.
ES466366A1 (es)	1978-10-01	Un procedimiento para preparar derivados de metasulfonamido-benzamida.
DK118287A (da)	1987-09-09	Heteroaryloxy-beta-carbolinderivater, deres fremstilling og deres anvendelse som laegemiddel
DK156655C (da)	1990-02-05	Pyridazinoner, fremgangsmaade til fremstilling deraf, anvendelse deraf og medikamenter indeholdende pyridazinoner
ATE107301T1 (de)	1994-07-15	Carbonsäurederivate.
DK188183D0 (da)	1983-04-27	Thiomethylpyridinderivater, fremgangsmade til deres fremstilling og laegemidler indeholdende disse forbindelser
DK160184D0 (da)	1984-03-20	Bis-(piperazinyl-eller homopiperazinyl)-alkaner og syreadditionssalte deraf,fremgangsmaade til deres fremstilling samt deres anvendelse
NO864665D0 (no)	1986-11-21	Nye basisk substituerte pyridinforbindelser, fremgangsmaate til deres fremstilling, legemiddel inneholdende dem, og deres anvendelse.
DK447284A (da)	1984-11-20	Aminoderivater af 2-(n-(2,2,5,5-tetramethyl-3-pyrrolin-3-carbonyl)),deres fremstilling og anvendelse
ES464013A1 (es)	1978-07-16	Procedimiento para preparar derivados sustituidos de orto- fenilendiamina.
ES8308546A1 (es)	1983-05-01	Procedimiento para la obtencion de derivados de diaril-imidazol.
DK165878C (da)	1993-06-21	3-substituerede-5-aminoalkyl-beta-carbolinderivater og fremgangsmaade til deres fremstilling
DK553482A (da)	1983-06-15	Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider
DK608586D0 (da)	1986-12-17	Polysubstituerede pyridin-1-oxider og fysiologisk aktive salte deraf, deres fremstilling og anvendelse som laegemidler
DK104488A (da)	1988-08-28	Acetamider afledt af 2,3-dihydro-3-phenyl-2-benzofuranon, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
NO960017L (no)	1996-07-05	Nye pseudopeptider med trifluormetylsubstituert 2-azabicyklooktan

Legal Events

Date	Code	Title	Description
2006-10-30	PBP	Patent lapsed	Country of ref document: DK