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DK66692D0 - En mammal cytokin, il-11 - Google Patents

En mammal cytokin, il-11

Info

Publication number
DK66692D0
DK66692D0 DK92666A DK66692A DK66692D0 DK 66692 D0 DK66692 D0 DK 66692D0 DK 92666 A DK92666 A DK 92666A DK 66692 A DK66692 A DK 66692A DK 66692 D0 DK66692 D0 DK 66692D0
Authority
DK
Denmark
Prior art keywords
cytokin
mammal
cells involved
stimulating
processes
Prior art date
Application number
DK92666A
Other languages
English (en)
Other versions
DK66692A (da
Inventor
Ya-Chung Yang
Frances K Bennett
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of DK66692D0 publication Critical patent/DK66692D0/da
Publication of DK66692A publication Critical patent/DK66692A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2073—IL-11
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5431—IL-11
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK066692A 1989-11-22 1992-05-21 En mammal cytokin, il-11 DK66692A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44110089A 1989-11-22 1989-11-22
US07/526,474 US5215895A (en) 1989-11-22 1990-05-21 Dna encoding a mammalian cytokine, interleukin-11
PCT/US1990/006803 WO1991007495A1 (en) 1989-11-22 1990-11-20 A mammalian cytokine, il-11

Publications (2)

Publication Number Publication Date
DK66692D0 true DK66692D0 (da) 1992-05-21
DK66692A DK66692A (da) 1992-07-22

Family

ID=27032674

Family Applications (2)

Application Number Title Priority Date Filing Date
DK90917548T DK0504177T3 (da) 1989-11-22 1990-11-20 IL-11, et pattedyrcytokin
DK066692A DK66692A (da) 1989-11-22 1992-05-21 En mammal cytokin, il-11

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK90917548T DK0504177T3 (da) 1989-11-22 1990-11-20 IL-11, et pattedyrcytokin

Country Status (13)

Country Link
US (4) US5215895A (da)
EP (1) EP0504177B1 (da)
JP (2) JP2688539B2 (da)
KR (1) KR970005050B1 (da)
AT (1) ATE199096T1 (da)
CA (1) CA2069428C (da)
DE (1) DE69033700T2 (da)
DK (2) DK0504177T3 (da)
ES (1) ES2156852T3 (da)
GR (1) GR3035627T3 (da)
HU (1) HU215233B (da)
MX (1) MX9203439A (da)
WO (1) WO1991007495A1 (da)

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US5215895A (en) * 1989-11-22 1993-06-01 Genetics Institute, Inc. Dna encoding a mammalian cytokine, interleukin-11
ATE167896T1 (de) * 1990-08-29 1998-07-15 Genetics Inst Aus mehreren domänen bestehende hämatopoese- stimulatoren
JP2752819B2 (ja) * 1990-11-08 1998-05-18 三共株式会社 新規サイトカイン
ATE238417T1 (de) 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US5460810A (en) * 1992-09-02 1995-10-24 Genetics Institute, Inc. Method for maintaining gut epithelial cells by treatment with a cytokine such as interleukin 11
US5602301A (en) * 1993-11-16 1997-02-11 Indiana University Foundation Non-human mammal having a graft and methods of delivering protein to myocardial tissue
KR100303810B1 (ko) * 1994-03-31 2001-12-01 스티븐 엠. 오드리 거핵구성장및분화를자극하기위한조성물및방법
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
US6270757B1 (en) * 1994-04-21 2001-08-07 Genetics Institute, Inc. Formulations for IL-11
US5582821A (en) * 1994-07-22 1996-12-10 Genetics Institute, Inc. Methods for treating bleeding disorders
US6274547B1 (en) 1996-06-14 2001-08-14 Genetics Institute, Inc. Methods comprising the use of human interleukin-11 receptor proteins
ATE342970T1 (de) 1994-12-22 2006-11-15 Genetics Inst Llc Verwendung eines menschlichen interleukin-11 rezeptors
US5760189A (en) * 1995-06-02 1998-06-02 Genetics Institute, Inc. Protein recovery & purification methods
US5824789A (en) * 1995-06-07 1998-10-20 Systemix, Inc. Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof
WO1996041607A2 (en) * 1995-06-09 1996-12-27 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising restrictin p/activin a and use thereof as antagonist of il-6 and/or il-11
US6887461B1 (en) * 1998-10-26 2005-05-03 Genetics Institute, Llc Method of using IL-11 for treating mucositis
US5679339A (en) * 1995-06-27 1997-10-21 Keith; James Method of using IL-11 for treating spondyloarthropies
US6540993B1 (en) 1995-06-27 2003-04-01 Wyeth Method of treating inflammatory bowel disease using a topical formulation of IL-11
US6126933A (en) * 1995-06-27 2000-10-03 Genetics Institute Methods of treating inflammatory bowel diseases by administering IL-11
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
EP0871472A4 (en) * 1995-10-27 2001-05-30 Amrad Operations Pty Ltd CYTOKINS AND THEIR USE IN TREATMENT AND / OR PREVENTION OF BREAST CANCER
KR100426286B1 (ko) * 1996-01-09 2004-06-30 주식회사 엘지생명과학 효모를이용한인간인터루킨-11의제조방법
AUPO439396A0 (en) 1996-12-24 1997-01-23 Walter And Eliza Hall Institute Of Medical Research, The A method of treatment and prophylaxis
ATE262919T1 (de) * 1998-01-23 2004-04-15 Inst Genetics Llc Verwendung von il-11 zur verstärkung der zellvermittelten immunität zur behandlung verschiedener viraler und parasitärer infektionen und krebs
CA2237915A1 (en) 1998-05-19 1999-11-19 Stephen Shaughnessy Osteoporosis treatment
US6265165B1 (en) * 1998-11-12 2001-07-24 The Regents Of The University Of California Methods for EST-specific full length cDNA cloning
AU3738300A (en) * 1999-03-11 2000-09-28 Genetics Institute Inc. Use of interleukin-11 to prevent immune-mediated cytotoxicity
US6953777B2 (en) * 1999-03-11 2005-10-11 Genetics Indtitute LLC Use of interleukin-11 to prevent immune-mediated cytotoxicity
WO2001007076A1 (en) * 1999-04-15 2001-02-01 Genetics Institute, Inc. Use of interleukin-11 to treat gastrointestinal disorders
US6274135B1 (en) * 1999-06-22 2001-08-14 Genetics Institute, Inc. Method of using IL-11 for inflammation associated with acute pancreatitis
BR0012429A (pt) * 1999-07-15 2002-09-17 Genetics Inst Fórmulações para il-11
WO2003049693A2 (en) * 2001-12-06 2003-06-19 Wyeth Method and composition for inducing weight loss
US6982080B2 (en) * 2002-03-15 2006-01-03 Wyeth Hydroxyethyl starch—containing polypeptide compositions
MXPA05002899A (es) * 2002-09-16 2005-05-27 Wyeth Corp Formulaciones de liberacion controlada para administracion oral de un agente terapeutico polipeptido y sus metodos de uso.
BRPI0413720A (pt) 2003-09-12 2006-10-17 Wyeth Corp bastões e pastas sólidas de fosfato de cálcio injetável para liberação de proteìnas osteogênicas
WO2005085283A1 (ja) * 2004-03-03 2005-09-15 Yamanouchi Pharmaceutical Co., Ltd. 修飾インターロイキン−１１及びそれを含有する医薬組成物
US20060166251A1 (en) * 2005-01-26 2006-07-27 Archambault Joanne M Use of sFRPs as markers of BMP activity
JP2009518418A (ja) * 2005-12-06 2009-05-07 ワイス インターロイキン１１組成物および使用法
US20080069796A1 (en) * 2006-07-31 2008-03-20 Kim Jong-Mook Low Dose Treatment with an Interleukin-11 Analog
WO2011151716A1 (en) 2010-06-04 2011-12-08 Lupin Limited Process for the purification of recombinant human il-11
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US9320777B2 (en) 2011-05-13 2016-04-26 Bolder Biotechnology, Inc. Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
EP3068866B1 (en) 2013-11-16 2018-04-25 Terumo BCT, Inc. Expanding cells in a bioreactor
EP3122866B1 (en) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11229683B2 (en) 2015-09-18 2022-01-25 Bolder Biotechnology, Inc. Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposure
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
EP3568410A4 (en) * 2017-01-16 2020-12-23 Nansha Biologics (Hong Kong) Limited SYSTEMS AND PROCESSES FOR THE PRODUCTION OF RECOMBINANT IL-11 IN YEAST
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
JP2024511064A (ja) 2021-03-23 2024-03-12 テルモ ビーシーティー、インコーポレーテッド 細胞捕獲及び増殖
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US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
US5215895A (en) * 1989-11-22 1993-06-01 Genetics Institute, Inc. Dna encoding a mammalian cytokine, interleukin-11
US5371193A (en) * 1990-05-21 1994-12-06 Genetics Institute, Inc. - Legal Affairs Mammalian cytokine, IL-11
JPH0571866A (ja) * 1991-09-17 1993-03-23 Matsushita Refrig Co Ltd 断熱箱体

Also Published As

Publication number Publication date
US5700664A (en) 1997-12-23
JP2783361B2 (ja) 1998-08-06
HU9201712D0 (en) 1992-09-28
JPH05504560A (ja) 1993-07-15
EP0504177B1 (en) 2001-02-07
US5854028A (en) 1998-12-29
DE69033700T2 (de) 2001-09-13
KR970005050B1 (ko) 1997-04-11
GR3035627T3 (en) 2001-06-29
HUT64595A (en) 1994-01-28
DK66692A (da) 1992-07-22
DK0504177T3 (da) 2001-04-02
HU215233B (hu) 1998-11-30
US5215895A (en) 1993-06-01
ATE199096T1 (de) 2001-02-15
ES2156852T3 (es) 2001-08-01
JPH104982A (ja) 1998-01-13
AU644389B2 (en) 1993-12-09
EP0504177A1 (en) 1992-09-23
AU6757890A (en) 1991-06-13
WO1991007495A1 (en) 1991-05-30
CA2069428C (en) 2001-07-31
US6066317A (en) 2000-05-23
CA2069428A1 (en) 1991-05-23
MX9203439A (es) 1992-08-01
JP2688539B2 (ja) 1997-12-10
KR920703819A (ko) 1992-12-18
DE69033700D1 (de) 2001-03-15

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