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DK656889A - Azabicykliske derivater - Google Patents

Azabicykliske derivater Download PDF

Info

Publication number
DK656889A
DK656889A DK656889A DK656889A DK656889A DK 656889 A DK656889 A DK 656889A DK 656889 A DK656889 A DK 656889A DK 656889 A DK656889 A DK 656889A DK 656889 A DK656889 A DK 656889A
Authority
DK
Denmark
Prior art keywords
azabicyclic derivatives
azabicyclic
derivatives
dementia
prophylaxis
Prior art date
Application number
DK656889A
Other languages
English (en)
Other versions
DK656889D0 (da
Inventor
Michael Stewart Hadley
Paul Adrian Wyman
Barry Sidney Orlek
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK656889D0 publication Critical patent/DK656889D0/da
Publication of DK656889A publication Critical patent/DK656889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Photoreceptors In Electrophotography (AREA)
DK656889A 1988-12-23 1989-12-21 Azabicykliske derivater DK656889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888830226A GB8830226D0 (en) 1988-12-23 1988-12-23 Novel compounds

Publications (2)

Publication Number Publication Date
DK656889D0 DK656889D0 (da) 1989-12-21
DK656889A true DK656889A (da) 1990-06-24

Family

ID=10649157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK656889A DK656889A (da) 1988-12-23 1989-12-21 Azabicykliske derivater

Country Status (13)

Country Link
US (1) US5043342A (da)
EP (1) EP0375450B1 (da)
JP (1) JPH02215782A (da)
KR (1) KR900009638A (da)
AT (1) ATE122352T1 (da)
AU (1) AU620957B2 (da)
CA (1) CA2006436A1 (da)
DE (1) DE68922596T2 (da)
DK (1) DK656889A (da)
GB (1) GB8830226D0 (da)
NZ (1) NZ231970A (da)
PT (1) PT92668B (da)
ZA (1) ZA899821B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
KR100441404B1 (ko) * 2002-01-24 2004-07-23 한국과학기술연구원 신규한 알케닐 아자 두 고리 화합물 및 그 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
GB1053085A (da) * 1964-03-26
US3501471A (en) * 1966-09-21 1970-03-17 American Cyanamid Co Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
JPS6191185A (ja) * 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
US4599344A (en) * 1984-10-31 1986-07-08 Schering A.G. Quinuclidines and quinuclidinium salts as antiarrhythmic agents
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
DE3877470T2 (de) * 1987-09-10 1993-06-24 Merck Sharp & Dohme Oxazole und thiazole zur behandlung seniler demenz.
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use

Also Published As

Publication number Publication date
AU4706489A (en) 1990-06-28
US5043342A (en) 1991-08-27
DE68922596T2 (de) 1995-09-28
CA2006436A1 (en) 1990-06-23
AU620957B2 (en) 1992-02-27
PT92668A (pt) 1990-06-29
DE68922596D1 (de) 1995-06-14
JPH02215782A (ja) 1990-08-28
EP0375450B1 (en) 1995-05-10
KR900009638A (ko) 1990-07-05
DK656889D0 (da) 1989-12-21
NZ231970A (en) 1992-01-29
ATE122352T1 (de) 1995-05-15
GB8830226D0 (en) 1989-02-22
EP0375450A2 (en) 1990-06-27
ZA899821B (en) 1990-12-28
PT92668B (pt) 1995-09-12
EP0375450A3 (en) 1991-07-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment